Recognition by peptide mapping of three different structural groups of outer membrane protein YOP-1 of Yersinia enterocolitica and Yersinia pseudotuberculosis.

abstract：:The new QuantiFERON-TB Gold Plus employs modified peptides optimized to elicit an IFNγ response from CD8+ cytotoxic T lymphocytes in addition to CD4+ T cells. With a view to improve the difficult identification of TB cases, we assessed the combination of two specific immunological markers comprising IFNγ secretion and...

journal_title：Medical microbiology and immunology

authors： Sauzullo I,Mengoni F,Mascia C,Pavone P,Savelloni G,Massetti AP,Lichtner M,Vullo V,Mastroianni CM

更新日期：2019-04-01 00:00:00

abstract：:Six colonies producing antibodies were obtained by fusing mouse myeloma SP2-O cells with spleen cells from mice immunized with cytomegalovirus Davis strain. Among 88 surviving clones, 29 produced antibodies detectable by immunofluorescence on infected MRC5 cells and 2 others produced neutralizing antibodies against a ...

journal_title：Medical microbiology and immunology

authors： Chardonnet Y,Léry X,Revillard JP

更新日期：1983-01-01 00:00:00

abstract：:Tests were made on 169 sera from children up to 10 years of age for rotavirus antibodies by indirect immunofluorescence and complement fixation tests. The simian strain SA 11 served as a substitute antigen for the human rotavirus. Furthermore, the SA 11 complement-fixing antigen was compared with a commercial antigen ...

journal_title：Medical microbiology and immunology

authors： Brade L,Schmidt WA

更新日期：1979-03-13 00:00:00

abstract：:Industrial and academic needs for innovation and fundamental research are essential and not widely different. Depending on the industrial setting, research and development (R&D) activities may be more focused on the developmental aspects given the need to ultimately sell useful products. However, one of the biggest di...

journal_title：Medical microbiology and immunology

authors： van Belkum A,Pelegrin AC,Datar R,Goyal M,Palmieri M,Mirande C,Chalansonnet V,Orenga S

更新日期：2020-06-01 00:00:00

abstract：:A sentinel surveillance system of the public health service for acute respiratory diseases (ARD), especially influenza, has been realized in the Free State of Saxony of Germany for 25 years. The epidemiological sentinel is based on weekly registration of morbidity and mathematical-statistical calculations. For a micro...

journal_title：Medical microbiology and immunology

authors： Bigl S,Briem I,Drechsler R,Kluge D,Müller L,Nowotnik G

更新日期：2002-12-01 00:00:00

abstract：:The presence of Borna disease virus (BDV)-specific RNA was traced by the reverse transcriptase-polymerase chain reaction in conjunctival fluid, nasal secretions and saliva of horses which were seropositive but did not have any history of clinical Borna disease. Positive reactions encompassed sequences encoding the p24...

journal_title：Medical microbiology and immunology

authors： Richt JA,Herzog S,Haberzettl K,Rott R

更新日期：1993-12-01 00:00:00

abstract：:To characterize the role of specific lymphocyte subsets in Chlamydia trachomatis infection, we established a murine model using the mouse pneumonitis agent (MoPn) of C. trachomatis and C.B-17 scid/scid (SCID) mice which lack functional B and T cells. After intraperitoneal inoculation with the bacteria, SCID mice devel...

journal_title：Medical microbiology and immunology

authors： Thoma-Uszynski S,Simnacher U,Marre R,Essig A

更新日期：1998-10-01 00:00:00

abstract：:A new way of measuring indirect immunofluorescence (IIF) of microscopic bacterial slide preparations by videocamera and an image processing system is presented. This method is compared with the conventional method of reading the slides by eye. The advantages of this new approach are objective reading, greater accuracy...

journal_title：Medical microbiology and immunology

authors： Apperloo-Renkema HZ,Wilkinson MH,Oenema DG,van der Waaij D

更新日期：1991-01-01 00:00:00

abstract：:Epidemiological studies in Mecklenburg-Vorpommern have shown a high prevalence of Borrelia burgdorferi-infected ticks. A total of 17 B. burgdorferi sensu lato strains were isolated from ticks and investigated by Western blots (immunoblot) with eight monoclonal anti-bodies against different epitopes of the outer surfac...

journal_title：Medical microbiology and immunology

authors： Lottmann H,Wilske B,Herrmann H

更新日期：1996-02-01 00:00:00

abstract：:We evaluated the long-term effects of the single oral administration of a new CXCR4 antagonist, KRH-3955, on elevation of white blood cell (WBC), neutrophil and lymphocyte counts in normal cynomolgus monkeys. In the monkeys treated with 0, 2, 20, 200 mg/kg of the compound, WBC, neutrophil and lymphocyte counts increas...

journal_title：Medical microbiology and immunology

authors： Nakasone T,Kumakura S,Yamamoto M,Murakami T,Yamamoto N

更新日期：2013-04-01 00:00:00

abstract：:A total of 603 serum samples obtained from 12 different patient and control groups, including potentially cross-reactive sera, were tested for the presence of antibodies against Kaposi's sarcoma-associated herpesvirus (KSHV, HHV-8). The assays used were an inhouse immunofluorescence test (IFT) employing latent KSHV an...

journal_title：Medical microbiology and immunology

authors： Preiser W,Szép NI,Lang D,Doerr HW,Rabenau HF

更新日期：2001-12-01 00:00:00

abstract：:The development in rabbits of antibodies against common thermolabile Escherichia coli surface antigens - and against O and K antigens - was investigated. Three strains, E3b (O75:K95:H5), E56b (O8:K27:H-), and H61 (O45:K1:H10), and five rabbits per strain were used. Immunization was carried out by routine procedures us...

journal_title：Medical microbiology and immunology

authors： Orskov F,Larsen JC,Orskov I

更新日期：1981-01-01 00:00:00

abstract：:NFR nude (nu/nu) and euthymic (+/nu) littermates were infected with coxsackievirus B3 (CBV-3) and assayed for virus persistence in the heart, pancreas and spleen, for development of myocarditis and for antibody production. The virus grew to higher titer and persisted longer in hearts of nu/nu mice. In both types of mi...

journal_title：Medical microbiology and immunology

authors： Schnurr DP,Schmidt NJ

更新日期：1984-01-01 00:00:00

abstract：:The fatal inhalation infection caused by Bacillus anthracis results from a complex pathogenic cycle involving release of toxins by bacteria that germinate from spores. Currently available vaccines against anthrax consist of protective antigen (PA), one of the anthrax toxin components. However, these PA-based vaccines ...

journal_title：Medical microbiology and immunology

authors： Sinha K,Bhatnagar R

更新日期：2013-04-01 00:00:00

abstract：:The pathogenesis of Staphylococcus aureus from local infection to systemic dissemination involves a range of virulence factors including structural and secreted products. Among various control mechanisms, small noncoding RNAs are involved in the regulation of multiple pathogenicity factors in S. aureus. The sRNA SprX ...

journal_title：Medical microbiology and immunology

authors： Kathirvel M,Buchad H,Nair M

更新日期：2016-12-01 00:00:00

abstract：:This is a summary of the recent work on some glycosidases of sand flies and their Leishmania parasites. Glycosidases catalyze the hydrolysis of complex sugar subunits of polysaccharides into simple sugars. Leishmania major parasites secrete chitinase and N-acetylglucosaminase, which enables them to survive in the gut ...

journal_title：Medical microbiology and immunology

authors： Jacobson RL,Schlein Y,Eisenberger CL

更新日期：2001-11-01 00:00:00

abstract：:Burkholderia pseudomallei, a gram-negative intracellular bacterium, is a causative agent of melioidosis. The bacterium has been shown to induce the innate immune response, particularly pro-inflammatory cytokine production in several of both mouse and human cell types. In the present study, we investigate host immune r...

journal_title：Medical microbiology and immunology

authors： Kulsantiwong P,Pudla M,Boondit J,Wikraiphat C,Dunachie SJ,Chantratita N,Utaisincharoen P

更新日期：2016-06-01 00:00:00

abstract：:Virus-induced antigens were isolated from MDV and HVT-infected cells by salt extraction with 3M KCl and purified by Con.A chromatography and isoelectric focusing. Electrophoretic analysis of 35S-methionine, 3H-fucose and 32P-orthophosphate labeled antigens revealed 7 different polypeptides, two of them containing labe...

journal_title：Medical microbiology and immunology

authors： Kaaden OR

更新日期：1977-10-07 00:00:00

abstract：:The purpose of this study was to characterize antigenic determinants on structural polypeptides of human immunodeficiency virus type 2 (HIV-2ben). Therefore, three HIV-2-specific monoclonal antibodies (mAbs) against the p24 core protein (gag) and one mAb against the gp130 envelope glycoprotein (env) were produced. In ...

journal_title：Medical microbiology and immunology

authors： Faisst AC,Otteken A,Nick S,Hunsmann G

更新日期：1993-07-01 00:00:00

abstract：:Oral candidiasis (OC) is a frequent oral manifestation of HIV infection, is a marker disease and occurs as a pseudomembranous, erythematous or rarely hyperplastic variant; angular cheilitis is also seen. Candida albicans is frequently isolated but other species such as C. krusei and C. dublienensis are emerging. Resis...

journal_title：Medical microbiology and immunology

authors： Reichart PA

更新日期：2003-08-01 00:00:00

abstract：:Adaptation of Borrelia burgdorferi in the vector and vertebrate host is mediated by mechanisms that regulate differential expression of outer surface lipoproteins (Osps). In this study, real time PCR was applied to quantify tissue-specific expression of four linear plasmid (lp54)-encoded (ospA, zs7.a36, zs7.a66 zs7.a6...

journal_title：Medical microbiology and immunology

authors： Lederer S,Brenner C,Stehle T,Gern L,Wallich R,Simon MM

更新日期：2005-01-01 00:00:00

abstract：:Several lines of evidence suggest a viral infection as the initiating event for the development of myocarditis (MC). Especially enteroviruses like coxsackie B3 virus have been shown to induce MC in humans and strains of MC-prone mice after an infection. The further course of the disease is, however, determined not onl...

journal_title：Medical microbiology and immunology

authors： Schwimmbeck PL,Bigalke B,Schulze K,Pauschinger M,Kühl U,Schultheiss HP

更新日期：2004-05-01 00:00:00

abstract：:Influenza remains an important threat for human health, despite the extensive study of influenza viruses and the production of effective vaccines. In contrast to virus genetics determinants, host genetic factors with clinical impact remained unexplored until recently. The association between three single nucleotide po...

journal_title：Medical microbiology and immunology

authors： Chatzopoulou F,Gioula G,Kioumis I,Chatzidimitriou D,Exindari M

更新日期：2019-10-01 00:00:00

abstract：:Cytotoxic effects of a leukocidin from Fusobacterium necrophorum were demonstrated on bovine hepatic cells. The cytotoxic response was dose-dependent and could be inhibited by homologous antiserum. Scanning electron microscopy revealed damaged hepatic cell surface. These findings indicated a pathogenic role of the leu...

journal_title：Medical microbiology and immunology

authors： Ishii T,Kanoe M,Inoue T,Kai K,Blobel H

更新日期：1988-01-01 00:00:00

abstract：:Recently we demonstrated that lack of mecA transcription was responsible for the decreased methicillin resistance phenotype of strongly slime-negative Staphylococcus epidermidis phase variants [Mempel M, Feucht H, Ziehbuhr W, Endres M, Laufs R, Grüter L (1994) Antimicrob Agents Chemother 38: 1251-1255]. In the present...

journal_title：Medical microbiology and immunology

authors： Mempel M,Müller E,Hoffmann R,Feucht H,Laufs R,Grüter L

更新日期：1995-10-01 00:00:00

abstract：:9 antigen distribution and sensitivity to the bactericidal effect of normal human serum were determined in 485 Proteus strains isolated from urine, blood, wounds, and feces. Of all strains, 62% could be grouped according to 25 0 antigens. The most frequent one, 0 3, appeared in 13% of all the strains. In blood culture...

journal_title：Medical microbiology and immunology

authors： Larsson P,Olling S

更新日期：1977-07-18 00:00:00

abstract：:The endogenous danger signal bradykinin was recently found implicated in the development of immunity against parasites via dendritic cells. We here report an essential role of the B(2) (B(2)R) bradykinin receptor in the early immune response against Listeria infection. Mice deficient in B(2)R (B(2)R(-/-) mice) were sh...

journal_title：Medical microbiology and immunology

authors： Kaman WE,Wolterink AF,Bader M,Boele LC,van der Kleij D

更新日期：2009-02-01 00:00:00

abstract：:Gangliosides are known to influence cell growth and differentiation. The neolacto series ganglioside IV3NeuAc-nLc4 (2-->3-sialosylparagloboside) is present in members of the monocyte/granulocyte lineage, but is not found in cells that belong to the lymphocyte lineage. In this study we demonstrated that IV3NeuAc-nLc4 i...

journal_title：Medical microbiology and immunology

authors： Schaade L,Kleines M,Walter R,Thomssen R,Ritter K

更新日期：1999-08-01 00:00:00

abstract：:We have studied the incidence of enterotoxigenic and enteropathogenic Escherichia coli strains associated with infant diarrhoeal disease in Galicia (North-west Spain). During a period of 9 months we isolated heat-labile enterotoxin-positive strains in 2.1% of children with diarrhoea examined, whereas the production of...

journal_title：Medical microbiology and immunology

authors： Blanco J,González EA,Bernárdez I,Varela BR

更新日期：1983-01-01 00:00:00

abstract：:As enteroviruses are mainly transmitted by the fecal-oral route, this study was initiated to investigate the nature of the binding of enteroviruses to human skin. Using poliovirus 1, Mahoney, we investigated the overall effectiveness of soap and water hand-washing of 1 and 5 min duration. The virus-skin interaction wa...

journal_title：Medical microbiology and immunology

authors： Schürmann W,Eggers HJ

更新日期：1985-01-01 00:00:00