Abstract:
:Turkey is seeing a steady rise in rates of HIV infection in the country. The number of individuals with HIV/AIDS was greater than 7000 in 2014 according to data released by the Ministry of Health, and heterosexual contacts were reported to be the main transmission routes. Istanbul has the highest number of reported cases of HIV infection. The aim of the study was to determine the prevalence of HIV-1 drug resistance in 50 heterosexual patients from Istanbul. The most prevalent subtype was found to be subtype B (56.2 %). Resistance-associated mutations were found in 14 patients with 6/14 patients being therapy-experienced and 8/14 therapy naive at the time point of analysis. With increasing number of patients who require treatment and the rapid up-scaling of the antiretroviral therapy in Turkey, HIV-1 drug resistance testing is recommended before starting treatment in order to achieve better clinical outcomes.
journal_name
Med Microbiol Immunoljournal_title
Medical microbiology and immunologyauthors
Köksal MO,Beka H,Lübke N,Verheyen J,Eraksoy H,Cagatay A,Kaiser R,Akgül B,Agacfidan Adoi
10.1007/s00430-015-0419-9subject
Has Abstractpub_date
2015-08-01 00:00:00pages
551-5issue
4eissn
0300-8584issn
1432-1831journal_volume
204pub_type
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