Abstract:
:One hundred consecutive patients with histologically confirmed colorectal cancer and an equal number of age- and sex-matched orthopaedic patients as hospital controls were interviewed about demographic, socioeconomic, biometric and medical variables. Cholecystectomy was significantly more frequent among cases than controls, but there was no side-predilection of the post-cholecystectomy tumours. The frequency of bowel evacuation was significantly higher among cases, particularly those with rectal cancer, an observation which appears contradictory to the 'prolonged bowel transit time--high colorectal cancer risk' hypothesis. No significant differences were found between cases and controls with respect to socioeconomic status, height and weight, smoking habits, use of laxatives and (for females) parity, age at first pregnancy, and age at menopause; however, cases appeared to be younger at menarche.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Papadimitriou C,Day N,Tzonou A,Gerovassilis F,Manousos O,Trichopoulos Ddoi
10.1093/ije/13.2.155subject
Has Abstractpub_date
1984-06-01 00:00:00pages
155-9issue
2eissn
0300-5771issn
1464-3685journal_volume
13pub_type
杂志文章abstract::Recent criticism of epidemiologic methods has focused on the limitations of 'black box' epidemiology, a pejorative label given to the simple identification of exposure-disease relationships. The assessment of mediation is an important tool for addressing this criticism. By using mediation analysis to open the black bo...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyn372
更新日期:2009-06-01 00:00:00
abstract::Maps of 14 cancer types in China appear to show distinctive geographical distributions, but principal components analysis reveals that they share an underlying pattern which reflects variations in urbanization. Differences in risk factors between rural and urban areas, the process of disease transition and geographica...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/15.2.268
更新日期:1986-06-01 00:00:00
abstract::Thyroid status is known to have an important bearing on the ability of a woman to conceive, and to bring a normal infant to term. Thyroid status has changed in a number of previously iodine deficient countries as a result of recent iodization programmes. In this study, examination has been made of changes in the rates...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/8.2.137
更新日期:1979-06-01 00:00:00
abstract::To examine whether chlorination of drinking water was associated with cancer of the digestive or other organs, an ecological epidemiological study using nationwide incidence data from the Cancer Registry of Norway was carried out. On two geographical levels (counties and municipalities), both for men and women, chlori...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/21.1.6
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:Complicated HIV transmission dynamics make it unclear how to design and interpret results from community-randomized controlled trials (CRCT) of interventions to prevent infection. METHODS:Mathematical modelling was used to investigate the effectiveness of interventions to prevent HIV transmission aimed at h...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dym232
更新日期:2008-02-01 00:00:00
abstract::This paper discusses the application of Popper's philosophy to epidemiological research, examining in particular the problems of replication without risk of refutation, of mistaking statistical sophistication for deductive inference, and of dealing with causality at a general level. An example is given of a Popperian ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/4.3.159
更新日期:1975-09-01 00:00:00
abstract::Coronary heart disease (CHD) is regarded as a disease of developed 'western' societies. Within developed societies, however, CHD is typically a disease of the less affluent socioeconomic classes. This has not always been the case. Forty years ago. CHD was reported to be more common among the upper social classes. In N...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.2.393
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:Child mortality estimates in Beirut are presented for the late 1970s and the mid 1980s, and changes in socio-religious differentials of mortality across time are investigated. METHODS:Baseline information was obtained from maternity registries in Beirut in 1984 and 1991. Age of mother, number of children ev...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/26.1.110
更新日期:1997-02-01 00:00:00
abstract::Aetiology confronts two distinct issues: the determinants of individual cases, and the determinants of incidence rate. If exposure to a necessary agent is homogeneous within a population, then case/control and cohort methods will fail to detect it: they will only identify markers of susceptibility. The corresponding s...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/14.1.32
更新日期:1985-03-01 00:00:00
abstract::Geographical variations in the declining rates of ischaemic heart disease (IHD) mortality may provide clues about various environmental risk factors responsible as a mass influence on the population IHD rate. The rate of IHD decline in 18 of 21 NJ counties was 2 to 45% less than the USA national rate of decline. The o...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.1.26
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:The Italian Longitudinal Study on Aging (ILSA) evaluates the rates of diabetes, cardiovascular and neurological disorders in a random sample of 5632 Italians aged 65-84 years. METHODS:The ILSA has two components: a first screening phase administered to all participants, that includes a personal interview, p...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/26.5.995
更新日期:1997-10-01 00:00:00
abstract::A study was made in five rural districts of Kwara State, Nigeria to assess the possible use of 'leopard skin' (Ls) as a rapid diagnostic technique for estimating the endemicity of African onchocerciasis. The findings revealed that there is a positive association between the percentage of subjects with skin microfilari...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/16.4.590
更新日期:1987-12-01 00:00:00
abstract:BACKGROUND:Sexual behaviour data are crucial for understanding the spread of sexually transmitted diseases (STD). Over a period (1987-1992) in which the HIV epidemic increased public awareness of safe sexual practices, we describe predictors of condom use, changes in condom use over time, and the estimated effects of t...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/24.4.813
更新日期:1995-08-01 00:00:00
abstract:BACKGROUND:Studies suggest that increased levels of physical activity might decrease the risk of prostate cancer. We ascertained lifetime measures of activity in a population-based case-control study of prostate cancer in Shanghai, China to investigate physical activity in a population where the incidence of prostate c...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/30.2.341
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:We examined the effect of a large reduction in the price of alcohol that occurred in Finland in 2004 on alcohol-related and all-cause mortality, and mortality due to cardiovascular diseases (CVDs) from which alcohol-attributable cases were excluded. METHODS:Time series intervention analysis modelling was ap...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyp336
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Smoking increases the risk of squamous-cell carcinoma of the cervix, but it is not clear whether smoking increases the risk of acquisition or persistence of human papillomavirus (HPV) infection. METHODS:Information on smoking was collected from 10 areas in four continents among population-based, age-stratif...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyn033
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Short stature has been associated with an increased risk of coronary heart disease (CHD), although the reason for the association remains unclear. Data on the relation between stature and stroke is more limited. We examined the association between stature and CHD as well as between stature and stroke in men ...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ije/27.6.970
更新日期:1998-12-01 00:00:00
abstract::Geoffrey Rose's 1985 paper, Sick individuals and sick populations, continues to spark debate and discussion. Since this original publication, there have been two notable challenges to Rose's population strategy of prevention. First, identification of high-risk individuals has improved considerably in accuracy, which s...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyp315
更新日期:2010-04-01 00:00:00
abstract::The proportional relationships of the four numbers in a 2 x 2 table can be displayed using two types of box graphs. In one approach, a 'unitary square' is first divided according to the denominator proportions of the two groups formed in a cohort or case-control study, and then re-divided according to the numerator pr...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/17.1.222
更新日期:1988-03-01 00:00:00
abstract:BACKGROUND:Data from several studies indicate that children of mothers who smoked during pregnancy may be at a risk of overweight compared with children of non-smoking mothers. The size of this relation, however, is unclear, as is the age at which it becomes detectable. METHODS:Prospective data for 34 866 children enr...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyi218
更新日期:2006-02-01 00:00:00
abstract::The CARTaGENE (CaG) study is both a population-based biobank and the largest ongoing prospective health study of men and women in Quebec. In population-based cohorts, participants are not recruited for a particular disease but represent a random selection among the population, minimizing the need to correct for bias i...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dys160
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:A recent monograph by the International Agency for Research on Cancer (IARC) has identified indoor air pollution from coal usage as a known human carcinogen, while that from biomass as a probable human carcinogen. Although as much as 74% of the Indian population relies on solid fuels for cooking, very little...
journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
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更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:The objective of this study is to measure the association between protein-energy malnutrition (PEM) in children and their mothers' mental health, in a low income area in the city of Embú, São Paulo, Brazil. METHODS:A case-control study was performed. Cases were 60 moderately and severely malnourished childr...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/25.1.128
更新日期:1996-02-01 00:00:00
abstract::Specificity of association between putative risk factor and disease under study is important to inference on causality. Nevertheless many studies investigate mortality of a single disease without comparison with a control. Age-standardized proportional mortality ratios make single disease studies into case-control stu...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/20.4.984
更新日期:1991-12-01 00:00:00
abstract:BACKGROUND:Syndromes for which no physical or pathological changes can be found tend to be researched and managed in isolation although hypotheses suggest that they may be one entity. The objectives of our study were to investigate the co-occurrence, in the general population, of syndromes that are frequently unexplain...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyi265
更新日期:2006-04-01 00:00:00
abstract::Mortalities from selected causes from 1973 to 1982 among Koreans, Chinese, and Americans residing in Japan were compared with those of Japanese. In the Korean population, besides the well-documented excess in mortalities from liver cancer, lung cancer, liver cirrhosis and male tuberculosis, a rather prominent elevatio...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/16.3.415
更新日期:1987-09-01 00:00:00
abstract:BACKGROUND:Under-5 mortality is unacceptably high in many countries, the burden of which is mainly borne by the poor. Whereas country characteristics are known to influence under-5 mortality, it is unknown whether these have a different impact on the poor and the rich. We aimed to describe how the association between u...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyi190
更新日期:2005-12-01 00:00:00
abstract::In this paper dot maps are used as an epidemiological tool to describe the spatial patterns of cases, non-cases and some relevant risk factors associated with the occurrence of Schistosoma mansoni infection in an urban environment. The study was carried out in Santo Antonio de Jesus, a town in north-east Brazil with a...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/22.4.731
更新日期:1993-08-01 00:00:00
abstract:BACKGROUND:Although cigarette smoking is considered to be the most important cause of lung cancer, smoking behaviour cannot fully explain the epidemiological characteristics of lung cancer in Taiwanese women, who rarely smoke but contract lung cancer relatively often. There are other causes of lung cancer that have pro...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/26.1.24
更新日期:1997-02-01 00:00:00
abstract:Background:To assess the worldwide variation of amyotrophic lateral sclerosis (ALS) incidence, we performed a systematic review and meta-analysis of population-based data published to date. Methods:We reviewed Medline and Embase up to June 2015 and included all population-based studies of newly diagnosed ALS cases, us...
journal_title:International journal of epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1093/ije/dyw061
更新日期:2017-02-01 00:00:00