Opening the Black Box: a motivation for the assessment of mediation.

abstract：BACKGROUND:Trisomy 18 (Edwards' syndrome, T18) is the second most common trisomy in man. We describe 118 children with regular T18 who were ascertained clinically and cytogenetically in the Kuwait Medical Genetics Centre during 1980-1997. METHODS:Ascertainment of T18 cases was performed shortly after birth. Chromosoma...

journal_title：International journal of epidemiology

authors： Naguib KK,Al-Awadi SA,Moussa MA,Bastaki L,Gouda S,Redha MA,Mustafa F,Tayel SM,Abulhassan SA,Murthy DS

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Evaluation of acquired immunodeficiency syndrome (AIDS) prevention strategies requires an on-going follow up of the frequency of human immunodeficiency virus (HIV-1) infection. The aim of this study was to examine the trends in prevalence and incidence of HIV-1 infection among injecting drug users (IDU) duri...

journal_title：International journal of epidemiology

authors： Hernández-Aguado I,Aviño MJ,Pérez-Hoyos S,González-Aracil J,Ruiz-Pérez I,Torrella A,García de la Hera M,Belda F,Fernández E,Santos C,Trullen J,Fenosa A

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:This study evaluated whether food insecurity and obesity were associated in a population sample in Trinidad. METHODS:A sample was drawn of 15 clusters of households, in north central Trinidad. Resident adults were enumerated. A questionnaire was administered including the short form Household Food Security ...

journal_title：International journal of epidemiology

authors： Gulliford MC,Mahabir D,Rocke B

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The aims of this study were to examine the prevalence of drug use, and how morbidity, use of health services, self-evaluated health, demographic pattern and lifestyle characteristics influence drug use in a general population. METHODS:The study was carried out in the municipality of Tromsø, Norway. A sample...

journal_title：International journal of epidemiology

authors： Eggen AE

更新日期：1994-12-01 00:00:00

abstract：:Data from the Stockholm Health of the Population Study in 1984 (n = 6217) show small differences in mean alcohol consumption and in the prevalence of high consumers in various socioeconomic and educational categories of both sexes. Among young people mean consumption was higher in those who had low formal education, e...

journal_title：International journal of epidemiology

authors： Romelsjö A

更新日期：1989-12-01 00:00:00

abstract：Background:We previously showed that low-dose computed tomography (LDCT) screening in asbestos-exposed workers is effective in detecting lung cancer (LC) at an early stage. Here, we evaluate whether LDCT screening could reduce mortality from LC in such a high-risk population. Methods:Within a cohort of 2433 asbestos-e...

journal_title：International journal of epidemiology

authors： Barbone F,Barbiero F,Belvedere O,Rosolen V,Giangreco M,Zanin T,Pisa FE,Meduri S,Follador A,Grossi F,Fasola G

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:There is considerable interest in estimating the causal effect of a range of maternal environmental exposures on offspring health-related outcomes. Previous attempts to do this using Mendelian randomization methodologies have been hampered by the paucity of epidemiological cohorts with large numbers of genot...

journal_title：International journal of epidemiology

authors： Evans DM,Moen GH,Hwang LD,Lawlor DA,Warrington NM

更新日期：2019-06-01 00:00:00

abstract：:The effects of household exposure to cigarette smoke on hospitalization and incidence of respiratory illness were examined among 2227 children at Chang-Ning District, Shanghai Municipality, People's Republic of China. The passive smoking quantity was estimated by total daily cigarette consumption of family members and...

journal_title：International journal of epidemiology

authors： Chen Y,Li WX,Yu SZ,Qian WH

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Several studies have been conducted to estimate the population prevalence of hypertension, or its diagnosis and treatment. There is no multinationally comparable information on the prevalence of hypercholesterolaemia, or its diagnosis and treatment, since individual studies are often not directly comparable....

journal_title：International journal of epidemiology

authors： Tolonen H,Keil U,Ferrario M,Evans A,WHO MONICA Project.

更新日期：2005-02-01 00:00:00

abstract：:In September 1665, an outbreak of plague occurred in Eyam, a small village 10 miles west of Sheffield, in an isolated valley of Derbyshire. Eighty per cent of the population died during the 14 months of the epidemic, a greater proportion than any other community in England. When plague threatened to cause panic and de...

journal_title：International journal of epidemiology

authors： Coleman MP

更新日期：1986-09-01 00:00:00

abstract：:Serial blood specimens from Rh-negative pregnant women sent to laboratory for Rh antibody testing were stored and used for influenza investigations. The study period covered three epidemics, each caused by a different variant of influenza A (H3N2) virus. The relationship between pre-epidemic haemagglutination inhibiti...

journal_title：International journal of epidemiology

authors： Pyhälä R,Aho K

更新日期：1975-06-01 00:00:00

abstract：:Operational research (OR) analysis provides information and systems to support decision making. In health care there are examples of OR being used to support decisions surrounding both the organization of health services and the treatment of individual patients. However, its uptake is currently low in spite of the inc...

journal_title：International journal of epidemiology

authors： Beech R

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Epidemiology in Latin America, as in the rest of the world, has been developed for the purpose of contributing towards understanding the causes and determinants of the phenomena of health and disease in specific contexts. However, in that continent it has specific characteristics. METHODS:The paper explores...

journal_title：International journal of epidemiology

authors： Barreto ML

更新日期：2004-10-01 00:00:00

abstract：Background:Interventions to mitigate fuel poverty and particularly energy efficiency façade retrofitting (EEFR) have demonstrated positive impacts on health but the impacts of EEFR interventions on cold-related mortality have not been studied in depth. We evaluated the impact of EEFR interventions in Barcelona on the a...

journal_title：International journal of epidemiology

authors： Peralta A,Camprubí L,Rodríguez-Sanz M,Basagaña X,Borrell C,Marí-Dell'Olmo M

更新日期：2017-08-01 00:00:00

abstract：:Aetiology confronts two distinct issues: the determinants of individual cases, and the determinants of incidence rate. If exposure to a necessary agent is homogeneous within a population, then case/control and cohort methods will fail to detect it: they will only identify markers of susceptibility. The corresponding s...

journal_title：International journal of epidemiology

authors： Rose G

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:The excess risk of fatal and non-fatal cerebrovascular disease in people from low socioeconomic positions is only partially explained by conventional cerebrovascular risk factors. This has led to the suggestion that poor psychosocial work environments provide important additional explanatory power. However, ...

journal_title：International journal of epidemiology

authors： Kivimäki M,Gimeno D,Ferrie JE,Batty GD,Oksanen T,Jokela M,Virtanen M,Salo P,Akbaraly TN,Elovainio M,Pentti J,Vahtera J

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Not every leprosy patient is equally effective in transmitting Mycobacterium leprae. We studied the spatial distribution of infection (using seropositivity as a marker) in the population to identify which disease characteristics of leprosy patients are important in transmission. METHODS:Clinical data and bl...

journal_title：International journal of epidemiology

authors： Bakker MI,Hatta M,Kwenang A,Faber WR,van Beers SM,Klatser PR,Oskam L

更新日期：2004-12-01 00:00:00

abstract：:To investigate the possible association between Alzheimer's disease and late maternal age at index birth, we conducted a collaborative re-analysis of existing case-control data sets. Of the 11 studies participating in the EURODEM project, four were included in the analyses regarding maternal age. In all four studies, ...

journal_title：International journal of epidemiology

authors： Rocca WA,van Duijn CM,Clayton D,Chandra V,Fratiglioni L,Graves AB,Heyman A,Jorm AF,Kokmen E,Kondo K

更新日期：1991-01-01 00:00:00

abstract：:Examinations of 'healthy' men in Helsinki and in rural west and east Finland in 1956 included estimation of total cholesterol and that in the HDL and beta fractions separated by electrophoresis. Vital status to the end of 1980 has been ascertained for all but eight of the 526 men aged 35-61 and for all but two of 261 ...

journal_title：International journal of epidemiology

authors： Keys A,Karvonen MJ,Punsar S,Menotti A,Fidanza F,Farchi G

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:The stability of mammalian serum and urine in large metabolomic investigations is essential for accurate, valid and reproducible studies. The stability of mammalian serum and urine, either processed immediately by freezing at -80 degrees C or stored at 4 degrees C for 24 h before being frozen, was compared i...

journal_title：International journal of epidemiology

authors： Dunn WB,Broadhurst D,Ellis DI,Brown M,Halsall A,O'Hagan S,Spasic I,Tseng A,Kell DB

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Sexual behaviour data are crucial for understanding the spread of sexually transmitted diseases (STD). Over a period (1987-1992) in which the HIV epidemic increased public awareness of safe sexual practices, we describe predictors of condom use, changes in condom use over time, and the estimated effects of t...

journal_title：International journal of epidemiology

authors： Stigum H,Magnus P,Veierød M,Bakketeig LS

更新日期：1995-08-01 00:00:00

abstract：:In tropical Africa, parasitic and infective diseases remain the predominant causes of mortality and morbidity, and health and epidemiological services are poorly developed. Experience elsewhere has shown the value of surveillance in the control of communicable diseases and this paper contains a brief review of the use...

journal_title：International journal of epidemiology

authors： Lucas AO

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:The protective effect of a vaccine following an outbreak is often measured by the vaccine efficacy statistic, namely one minus the ratio of attack rates in vaccinees and non-vaccinees. This quantity is not an adequate measure of the population-level benefits of the vaccine. METHODS:We discuss two measures o...

journal_title：International journal of epidemiology

authors： Haber M,Watelet L,Halloran ME

更新日期：1995-12-01 00:00:00

abstract：:The reliability of casual blood pressures for reflecting blood pressure status and predicting cardiovascular sequelae of hypertension was examined in the Framingham cohort of 5209 men and women followed for 18 years. Blood pressures were more variable in persons with higher levels. After controlling for pressure level...

journal_title：International journal of epidemiology

authors： Gordon T,Sorlie P,Kannel WB

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Predictions of primary liver cancer (PLC) incidence rates and case numbers are critical to understand and plan for PLC disease burden. METHODS:Data on PLC incidence rates and case numbers from 1990 to 2017 were retrieved from the Global Burden of Disease database. The estimated average percentage change (EA...

journal_title：International journal of epidemiology

authors： Liu Z,Xu K,Jiang Y,Cai N,Fan J,Mao X,Suo C,Jin L,Zhang T,Chen X

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND:The increased odds of stomach cancer among subjects with blood type A have been reported in epidemiological studies. AIM:To study the relation of family history of gastric cancer and ABO blood type with precancerous gastric lesions in a high-risk area for stomach cancer. Subjects and setting We examined 340...

journal_title：International journal of epidemiology

authors： You WC,Ma JL,Liu W,Gail MH,Chang YS,Zhang L,Hu YR,Fraumeni JF Jr,Xu GW

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Recent studies suggest that small newborns who present rapid postnatal growth may have an increased risk of chronic diseases in adulthood. On the other hand, it is widely assumed that catch-up growth is desirable for low birthweight children, but the literature on this subject is limited. METHODS:Population...

journal_title：International journal of epidemiology

authors： Victora CG,Barros FC,Horta BL,Martorell R

更新日期：2001-12-01 00:00:00

abstract：:Management of medical services necessitates decisions regarding the possibly ineffective treatment programmes, hospitals and (even) individual practitioners. Although rigorous evaluations of effectiveness can only be achieved by randomized trials there has been, in recent years, much increase in audit (or peer review)...

journal_title：International journal of epidemiology

authors： West RR,Willis JD

更新日期：1983-12-01 00:00:00

abstract：:In this study, we derive national estimates of the prevalence of children's exposure to parental smoking in West Germany. The estimates are based on a national health survey conducted in 1987 and refer to those parents living in the same household as the child. Estimated prevalences of maternal smoking range from 18.9...

journal_title：International journal of epidemiology

authors： Brenner H,Mielck A

更新日期：1993-10-01 00:00:00

abstract：:Estimating the number of people in hidden populations is needed for public health research, yet available methods produce highly variable and uncertain results. The Anchored Multiplier calculator uses a Bayesian framework to synthesize multiple population size estimates to generate a consensus estimate. Users submit p...

journal_title：International journal of epidemiology

authors： Wesson PD,McFarland W,Qin CC,Mirzazadeh A

更新日期：2019-12-01 00:00:00