Inhibitory effects of fetal calf serum on proliferation of chick neuroblasts in culture.

abstract：:α-Synuclein is one of the most abundant proteins in presynaptic terminals. Normal expression of α-synuclein is essential for neuronal survival and it prevents the initiation of apoptosis in neurons through covalent cross-linking of cytochrome c released from mitochondria. Exocytosis of α-synuclein occurs with neuronal...

journal_title：Developmental neuroscience

authors： Su E,Bell MJ,Wisniewski SR,Adelson PD,Janesko-Feldman KL,Salonia R,Clark RS,Kochanek PM,Kagan VE,Bayır H

更新日期：2010-01-01 00:00:00

abstract：:The cerebromicrovasculature of immature mice ranging in age from 1-24 days after birth was studied by electron microscopy. A micromanipulator apparatus enabled us to facilitate direction of a needle cannula and injection into leg veins or hearts with horseradish peroxidase (HRP) or ferritin (anionic and cationic) trac...

journal_title：Developmental neuroscience

authors： Lossinsky AS,Vorbrodt AW,Wisniewski HM

更新日期：1986-01-01 00:00:00

abstract：:It has been hypothesized that changes in striatal-mediated dopamine modulation during adolescence may increase the risk for initiating substance abuse as a result of its fundamental role in arbitrating reward sensitivity and motivation during learning and decision making. However, substance abuse during adolescence ma...

journal_title：Developmental neuroscience

authors： Churchwell JC,Carey PD,Ferrett HL,Stein DJ,Yurgelun-Todd DA

更新日期：2012-01-01 00:00:00

abstract：:In the presence of nerve growth factor (NGF) PC12 pheochromocytoma cells develop properties of sympathetic neurons and extend long microtubule-containing neurites. PC12 cell microtubule protein was isolated using an assembly and disassembly procedure, either directly from an unlabeled cell extract or by copolymerizati...

journal_title：Developmental neuroscience

authors： Richter-Landsberg C,Landreth GE,Shooter EM

更新日期：1983-01-01 00:00:00

abstract：:The incidence of stroke in children is 2.4 per 100,000 person-years and results in long-term motor and cognitive disability. In ischemic stroke, white matter (WM) is frequently injured, but is relatively understudied compared to grey matter injury. Previous research suggests that the cellular response to WM ischemic i...

journal_title：Developmental neuroscience

authors： Dingman AL,Rodgers KM,Dietz RM,Hickey SP,Frazier AP,Clevenger AC,Yonchek JC,Traystman RJ,Macklin WB,Herson PS

更新日期：2019-03-12 00:00:00

abstract：:Prenatal stress has been associated with detrimental outcomes of pregnancy, including altered brain development leading to behavioural pathologies. The neurosteroid allopregnanolone has been implicated in mediating some of these adverse outcomes following prenatal stress due to its potent inhibitory and anxiolytic eff...

journal_title：Developmental neuroscience

authors： Bennett GA,Palliser HK,Shaw JC,Walker D,Hirst JJ

更新日期：2015-01-01 00:00:00

abstract：:The lipids of white matter and peripheral nerve from mutant mice with known myelin deficiencies were analyzed by one- and two-dimensional high-performance thin-layer chromatography and quantitated by densitometry. In optic nerve, the mutants jp/Y, jpmsd/Y, qk/qk, shi/shi and shimld/shimld, which have severe central ne...

journal_title：Developmental neuroscience

authors： Ganser AL,Kerner AL,Brown BJ,Davisson MT,Kirschner DA

更新日期：1988-01-01 00:00:00

abstract：:In this study we have examined the susceptibility of the mitochondrial respiratory chain of astrocytes and astrocytes depleted of glutathione to peroxynitrite exposure. Astrocytes, as reported previously by us, appeared resistant to the actions of peroxynitrite. In contrast, depletion (-94%) of astrocytic glutathione ...

journal_title：Developmental neuroscience

authors： Barker JE,Bolaños JP,Land JM,Clark JB,Heales SJ

更新日期：1996-01-01 00:00:00

abstract：:This study analyzed the role of dopamine D1 and D2 receptors in methylphenidate (MPH) conditioned place preference (CPP) in adolescent male and female rats, in addition to the role of these receptors in the effects of MPH on brain-derived neurotrophic factor (BDNF) in the dorsal striatum and nucleus accumbens. Using a...

journal_title：Developmental neuroscience

authors： Cummins ED,Griffin SB,Duty CM,Peterson DJ,Burgess KC,Brown RW

更新日期：2014-01-01 00:00:00

abstract：:Excitotoxicity plays a key role during insults to the developing brain such as neonatal encephalopathy, stroke, and encephalopathy of prematurity. Such insults affect many thousands of infants each year. Excitotoxicity causes frank lesions due to cell death and gliosis and disturbs normal developmental process, leadin...

journal_title：Developmental neuroscience

authors： Blaise BJ,Schwendimann L,Chhor V,Degos V,Hodson MP,Dallmann G,Keller M,Gressens P,Fleiss B

更新日期：2017-01-01 00:00:00

abstract：:To define the effects of neurotrophins on oligodendrocytes, we monitored NGF, BDNF and NT-3 actions on basal forebrain (BF) and cortical populations. NGF, BDNF and NT-3 applied to BF oligodendrocytes elicited increases in expression of myelin basic protein (MBP) and enhanced the numbers of MBP+ cells, without affectin...

journal_title：Developmental neuroscience

authors： Du Y,Fischer TZ,Lee LN,Lercher LD,Dreyfus CF

更新日期：2003-03-01 00:00:00

abstract：:This study investigated the time of expression of two endothelial cell adhesion molecules, ICAM-1/CD54 and PECAM-1/CD31 in the developing postpartum mouse blood-brain barrier (BBB). Immunoultrastructural studies demonstrated that both adhesion molecules are initially expressed primarily on the luminal endothelial cell...

journal_title：Developmental neuroscience

authors： Lossinsky AS,Wisniewski HM

更新日期：1998-01-01 00:00:00

abstract：:We have previously shown that a single intracranial injection of apotransferrin (aTf) in neonatal rats produces an accelerated mylinogenesis and increases the expression of certain myelin proteins such as myelin basic protein (MBP). In the present work, we studied the effects of aTf upon oligodendrocyte progenitor cel...

journal_title：Developmental neuroscience

authors： Paez PM,Marta CB,Moreno MB,Soto EF,Pasquini JM

更新日期：2002-01-01 00:00:00

abstract：:The development of the chick bulbar cardiac ganglia has been studied ultrastructurally from the 3rd day of incubation to hatching. For descriptive purposes, their development has been divided into three phases. The first phase includes migration and aggregation of undifferentiated neuroblasts, stages 21-26 (day 3.5-5)...

journal_title：Developmental neuroscience

authors： Kirby ML,Weidman TA,McKenzie JW

更新日期：1980-01-01 00:00:00

abstract：:Early developmental treatment of rats with 3,4-methylenedioxymethamphetamine (MDMA) was previously found to cause an abnormal pattern of forebrain serotonergic axon density in adulthood consisting of a cortical hypoinnervation and a striatal hyperinnervation. The present study tested the hypothesis that this reorganiz...

journal_title：Developmental neuroscience

authors： Piper BJ,Farelli JD,Meyer JS

更新日期：2009-01-01 00:00:00

abstract：:Proper eye formation depends on specific interactions between neural and ectodermal tissues coupled with temporally distinct gene expression and a regulated sequence of signaling events. The homeobox gene Pax6 is vitally important to the entire process of eye development in both vertebrates and invertebrates. Pax6 exp...

journal_title：Developmental neuroscience

authors： Reza HM,Yasuda K

更新日期：2004-01-01 00:00:00

abstract：:Cerebral metabolism is known to be highly dependent upon glucose utilisation. In the neonate, severe hypoglycaemia is now recognized to be associated with subsequent adverse neurodevelopment and in extremis glial and neuronal cell death. However, the level at which hypoglycaemia becomes clinically important is not wel...

journal_title：Developmental neuroscience

authors： Land JM

更新日期：1994-01-01 00:00:00

abstract：:Myelin-associated oligodendrocytic basic protein (MOBP) and myelin basic protein (MBP) share many structural similarities. MOBP is synthesised by mature oligodendrocytes and localised at the major dense line (MDL), suggesting a role in the myelin compaction process. The shiverer mouse, a deletion mutant of the myelin ...

journal_title：Developmental neuroscience

authors： Montague P,Kirkham D,McCallion AS,Davies RW,Kennedy PG,Klugmann M,Nave K,Griffiths IR

更新日期：1999-01-01 00:00:00

abstract：:The L-type calcium channel activator +/-Bay K 8644 has recently been shown to provoke self-injurious biting in young mice. Since the serotonergic systems have been implicated in the expression of self-injurious behavior in both humans and animals, the present studies tested whether drugs influencing serotonin systems ...

journal_title：Developmental neuroscience

authors： Kasim S,Egami K,Jinnah HA

更新日期：2002-01-01 00:00:00

abstract：:Systemic creatine (Cr) supplementation increases brain phosphocreatine (PCr) and prevents hypoxic seizures in 15-day-old rabbits. Between 5 and 30 days of age during normal development, rabbit gray matter mitochondrial creatine kinase (Mi-CK) increases 400% while cytosolic CK (BB-CK) increases 60%. In white matter, bo...

journal_title：Developmental neuroscience

authors： Kekelidze T,Khait I,Togliatti A,Holtzman D

更新日期：2000-09-01 00:00:00

abstract：:In vertebrate species, the neuropeptide oxytocin (OT) has been implicated in neural and behavioral development. Although several OT-like peptides have been characterized in invertebrate species, the ontogenesis of the OT-like system has not yet been described in these species. Thus, the aim of the present study was to...

journal_title：Developmental neuroscience

authors： Bardou I,Maubert E,Leprince J,Chichery R,Dallérac G,Vaudry H,Agin V

更新日期：2010-03-01 00:00:00

abstract：:There are distinct symptoms for attention deficit hyperactivity disorder (ADHD) at different ages. To explore the developmental mechanism of ADHD from childhood to adolescence, patients from different age groups with ADHD drawn from a large dataset should be investigated. In this study, we hypothesized that there are ...

journal_title：Developmental neuroscience

authors： Tang C,Wei Y,Zhao J,Nie J

更新日期：2018-01-01 00:00:00

abstract：:Rabbit central (CNS) and peripheral nervous system (PNS) myelin, as well as nonmyelinating pig oligodendrocytes in culture, were extracted at 0-4 degrees C with the nonionic detergent Triton X-114. The solubilized proteins were partitioned into the detergent-rich and detergent-depleted (aqueous) phases that form upon ...

journal_title：Developmental neuroscience

authors： Bürgisser P,Matthieu JM

更新日期：1989-01-01 00:00:00

abstract：:The hippocampal formation is a multicomponent region of the medial temporal lobe preferentially involved in declarative and relational memory processing. Behavioral studies have suggested a protracted functional maturation of these structures in primates, and postnatal developmental abnormalities in the hippocampal fo...

journal_title：Developmental neuroscience

authors： Lavenex P,Banta Lavenex P,Amaral DG

更新日期：2007-01-01 00:00:00

abstract：:Neonatal stroke leads to mortality and severe morbidity, but there is no effective treatment currently available. Erythropoietin (EPO) has been shown to promote cytoprotection and neurogenesis and decrease subventricular zone morphologic changes following brain injury. The long-term cellular response to EPO has not be...

journal_title：Developmental neuroscience

authors： Gonzalez FF,McQuillen P,Mu D,Chang Y,Wendland M,Vexler Z,Ferriero DM

更新日期：2007-01-01 00:00:00

abstract：:Hypoxic-ischemic brain injury is a leading cause of neurodevelopmental morbidities in preterm and full-term infants. Blood-brain barrier dysfunction represents an important component of perinatal hypoxic-ischemic brain injury. The extracellular matrix (ECM) is a vital component of the blood-brain barrier. Matrix metal...

journal_title：Developmental neuroscience

authors： Chen X,Patra A,Sadowska GB,Stonestreet BS

更新日期：2018-01-01 00:00:00

abstract：:We report on the effects of etiology and age on the linguistic outcomes in a large pediatric hemispherectomy population. Four populations were considered separately: cortical dysplasia (multilobar involvement), Rasmussen's encephalitis, infarction as a primary etiology and, fourth, children who failed to develop langu...

journal_title：Developmental neuroscience

authors： Curtiss S,de Bode S

更新日期：1999-11-01 00:00:00

abstract：:Prior studies suggest that non-canonical proteolipid protein (PLP) gene expression occurs during development in non-myelinating neurons as well as myelinating oligodendroglia in mammalian brain. To assess this possibility in neostriatum, a region of uncertain PLP gene expression in neurons, morphological and electroph...

journal_title：Developmental neuroscience

authors： Fulton D,Paez P,Spreur V,Handley V,Colwell CS,Campagnoni A,Fisher R

更新日期：2011-01-01 00:00:00

abstract：:Developing neurons synthesize substantial quantities of membrane phospholipids in producing new synapses. We investigated the effects of maternal uridine (as uridine-5'-monophosphate) and docosahexaenoic acid supplementation on pups' brain phospholipids, synaptic proteins and dendritic spine densities. Dams consumed n...

journal_title：Developmental neuroscience

authors： Cansev M,Marzloff G,Sakamoto T,Ulus IH,Wurtman RJ

更新日期：2009-01-01 00:00:00

abstract：:Developmental changes in gangliosides in the course of neurite outgrowth were examined in dissociated fetal rat cerebral neurons in culture. About a 2-fold increase in ganglioside levels was seen with the progression of neurite formation for up to 24 h in predominantly neuronal cultures. Ganglioside patterns appeared ...

journal_title：Developmental neuroscience

authors： Ogiso M,Ohta M,Harada Y,Hirano S

更新日期：1992-01-01 00:00:00