Different Developmental Pattern of Brain Activities in ADHD: A Study of Resting-State fMRI.

abstract：:The neonatal brain appears to be selectively vulnerable to oxidative stress. Several potential mechanisms associated with altered reactive oxygen species metabolism would explain the increased susceptibility. They include increased accumulation of hydrogen peroxide with subsequent neurotoxicity. This enhanced neurotox...

journal_title：Developmental neuroscience

authors： Ferriero DM

更新日期：2001-01-01 00:00:00

abstract：:Several studies have shown that exogenous gangliosides can stimulate neurite outgrowth (in vitro), accelerate peripheral nerve regeneration (in vivo) and facilitate CNS recovery after lesioning. Experiments were designed to assess the effects of ganglioside administration on neonatal development. Rat neonates received...

journal_title：Developmental neuroscience

authors： Karpiak SE,Vilim F,Mahadik SP

更新日期：1983-01-01 00:00:00

abstract：:Recent studies have shown a protection from cerebral hypoxic-ischemic (HI) brain damage in the immature rat following a prior systemic hypoxic exposure when compared with those not exposed previously. To investigate the mechanism(s) of hypoxic preconditioning, brain glycogen and high-energy phosphate reserves were mea...

journal_title：Developmental neuroscience

authors： Brucklacher RM,Vannucci RC,Vannucci SJ

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Therapeutic hypothermia provides incomplete neuroprotection for neonatal hypoxic-ischemic encephalopathy (HIE). We examined whether hemodynamic goals that support autoregulation are associated with decreased brain injury and whether these relationships are affected by birth asphyxia or vary by anatomic regio...

journal_title：Developmental neuroscience

authors： Lee JK,Poretti A,Perin J,Huisman TAGM,Parkinson C,Chavez-Valdez R,O'Connor M,Reyes M,Armstrong J,Jennings JM,Gilmore MM,Koehler RC,Northington FJ,Tekes A

更新日期：2017-01-01 00:00:00

abstract：:In the development of an integrated approach to study metabolic compartmentation and regulation in brain, we have emphasized the importance, versatility, and need to exploit the recent methodological advances in (1) NMR spectroscopy, (2) primary cultures of neurons and glial cells, and (3) subcellular fractionation (e...

journal_title：Developmental neuroscience

authors： Lai JC,Behar KL

更新日期：1993-01-01 00:00:00

abstract：:We studied the developmental changes of soluble and membrane-bound protein kinases (EC 2.7.1.37) in rat brain and found that the elution profiles from a DEAE-cellulose column by NaCl of adenosine-3':5'-monophosphate (cyclic AMP) dependent protein kinase from cytosol were not significantly different in newborn (0.19 M ...

journal_title：Developmental neuroscience

authors： Kinnier WJ,Chikvaidze V,Hollenbeck RA,Chuang DM,Costa E

更新日期：1979-01-01 00:00:00

abstract：:The effect of undernutrition on the activity of glutamate decarboxylase (GAD) and choline acetyltransferase (ChAc) (markers for the GABA-ergic and the cholinergic transmitter system, respectively) was studied in various parts of the rat brain at the age of 10, 15 and 21 days, and at day 54 following 33 days of rehabil...

journal_title：Developmental neuroscience

authors： Patel AJ,del Vecchio M,Atkinson DJ

更新日期：1978-01-01 00:00:00

abstract：:It has been demonstrated that postweaning social isolation alters dendritic development in the medial prefrontal cortex (mPFC) of the rat. In addition, (-)-deprenyl, a monoamine oxidase B (MAO-B) inhibitor, promotes dendritic growth in prefrontocortical pyramidal cells. This study examined whether prefrontocortical de...

journal_title：Developmental neuroscience

authors： Pascual R,Zamora-León SP

更新日期：2007-01-01 00:00:00

abstract：:Evidence from retroviral marking techniques and immortalized cell lines indicates that multipotential stem cells exist in many areas of the developing central nervous system. However, the factors that influence the commitment of these stem cells into distinct neuronal or glial lineages are not known. We have created a...

journal_title：Developmental neuroscience

authors： Marone M,Quiñones-Jenab V,Meiners S,Nowakowski RS,Ho SY,Geller HM

更新日期：1995-01-01 00:00:00

abstract：:Oligodendrocytes from the shiverer mutant mouse are missing most of the myelin basic protein (Mbp) gene. In axon-free cultures, they produce membrane sheets with abnormally assembled microtubule and actin-based structures. This suggests that an Mbp gene product may have an important role in regulating the organization...

journal_title：Developmental neuroscience

authors： Dyer CA,Phillbotte T,Wolf MK,Billings-Gagliardi S

更新日期：1997-01-01 00:00:00

abstract：:Adult GM2 gangliosidosis is a rare autosomal recessive disease with widely varying neurological and psychiatric manifestations. It is caused by marked deficiency, but not total absence, of beta-hexosaminidase (Hex) A, due to a single base change in the alpha-subunit gene of Hex, resulting in a substitution of Ser for ...

journal_title：Developmental neuroscience

authors： Navon R

更新日期：1991-01-01 00:00:00

abstract：:We investigated the effects of perinatal hypoxia-ischemia (HI) on brain injury and neurological functional outcome at postnatal day (P)30 through P90. HI was induced by exposing P9 mice to 8% O(2) for 55 min using the Vannucci HI model. Following HI, mice were treated with either vehicle control or Na(+)/H(+) exchange...

journal_title：Developmental neuroscience

authors： Cengiz P,Uluc K,Kendigelen P,Akture E,Hutchinson E,Song C,Zhang L,Lee J,Budoff GE,Meyerand E,Sun D,Ferrazzano P

更新日期：2011-01-01 00:00:00

abstract：:The kinetics and sodium-dependence of gamma-aminobutyric acid (GABA), hypotaurine and taurine uptake were analyzed in cerebral slices prepared from mice of different postnatal ages. The maximal velocities of transport (V) and the Km constants for the high-affinity uptake all decreased with age, whereas the development...

journal_title：Developmental neuroscience

authors： Oja SS,Kontro P

更新日期：1983-01-01 00:00:00

abstract：:Systemic creatine (Cr) supplementation increases brain phosphocreatine (PCr) and prevents hypoxic seizures in 15-day-old rabbits. Between 5 and 30 days of age during normal development, rabbit gray matter mitochondrial creatine kinase (Mi-CK) increases 400% while cytosolic CK (BB-CK) increases 60%. In white matter, bo...

journal_title：Developmental neuroscience

authors： Kekelidze T,Khait I,Togliatti A,Holtzman D

更新日期：2000-09-01 00:00:00

abstract：:Metabolism of glutamate and glutamine in cultured mouse cerebral cortical astrocytes has been investigated using either radioactively labelled (14C) amino acids or 13C-labelled amino acids combined with NMR spectroscopy of cell extracts and lyophilyzed incubation media. Using [U-13C]glutamate it has been shown that in...

journal_title：Developmental neuroscience

authors： Schousboe A,Westergaard N,Sonnewald U,Petersen SB,Huang R,Peng L,Hertz L

更新日期：1993-01-01 00:00:00

abstract：:Adrenoleukodystrophy (ALD) is an X-linked recessive disorder that affects mainly the nervous system white matter and the adrenal cortex. It is associated with an abnormal accumulation of saturated very long chain fatty acids and can be diagnosed by demonstrating an excess of these substances in plasma or red cells. Ou...

journal_title：Developmental neuroscience

authors： Moser HW,Moser AB,Naidu S,Bergin A

更新日期：1991-01-01 00:00:00

abstract：:Maternal infection during pregnancy increases the risk of neurobehavioral problems in offspring. Evidence from rodent models indicates that the maternal immune response to infection can alter fetal brain development, particularly in the hippocampus. However, information on the effects of maternal viral infection on fe...

journal_title：Developmental neuroscience

authors： Antonson AM,Balakrishnan B,Radlowski EC,Petr G,Johnson RW

更新日期：2018-01-01 00:00:00

abstract：:L-Ornithine decarboxylase (ODC), the rate-limiting enzyme of polyamine biosynthesis and thus a unique marker of the proliferation and maturation processes, has been localized by means of immunohistochemistry in the human central nervous system. The enzyme protein has not only been found in the developing nervous syste...

journal_title：Developmental neuroscience

authors： Müller M,Pajunen AE,Järvinen M,Poeggel G,Bernstein HG

更新日期：1993-01-01 00:00:00

abstract：:Early developmental treatment of rats with 3,4-methylenedioxymethamphetamine (MDMA) was previously found to cause an abnormal pattern of forebrain serotonergic axon density in adulthood consisting of a cortical hypoinnervation and a striatal hyperinnervation. The present study tested the hypothesis that this reorganiz...

journal_title：Developmental neuroscience

authors： Piper BJ,Farelli JD,Meyer JS

更新日期：2009-01-01 00:00:00

abstract：:Nogo is a member of the reticulon family. Our understanding of the physiological functions of the Nogo-A protein has grown over the last few years, and this molecule is now recognized as one of the most important axonal regrowth inhibitors present in central nervous system (CNS) myelin. Nogo-A plays other important ro...

journal_title：Developmental neuroscience

authors： Haybaeck J,Llenos IC,Dulay RJ,Bettermann K,Miller CL,Wälchli T,Frei K,Virgintino D,Rizzi M,Weis S

更新日期：2012-01-01 00:00:00

abstract：:The norepinephrine content of hypothalamus in vehicle-treated control rats gradually increases between days 16 and 45 of life. Norepinephrine contents of the hypothalamus and mesencephalon of the thyroxine-treated (10 microgram/g b.w., s.c., days 8-10) animals also increase between days 16 and 21. Mesencephalic and hy...

journal_title：Developmental neuroscience

authors： Lengvári I,Branch BJ,Taylor AN

更新日期：1980-01-01 00:00:00

abstract：:We have used whole-cell and single-channel recording techniques to investigate the electrophysiological properties of cultured ovine oligodendrocytes (OLGs). Our studies have led to the following conclusions. (1) Cultured mature OLGs express a variety of voltage-dependent K+ conductances including an outward current t...

journal_title：Developmental neuroscience

authors： Soliven B,Szuchet S,Arnason BG,Nelson DJ

更新日期：1989-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) have been reported to affect neural stem cell self-renewal and therefore may be important for normal development and may influence neurodegenerative processes when ROS activity is elevated. To determine if increasing production of superoxide, via activation of NADPH oxidase (Nox), increas...

journal_title：Developmental neuroscience

authors： Topchiy E,Panzhinskiy E,Griffin WS,Barger SW,Das M,Zawada WM

更新日期：2013-01-01 00:00:00

abstract：:Insulin binding was measured on crude mitochondrial or plasma membranes prepared from different rat brain regions during postnatal development. In the cerebral cortex and brainstem, insulin binding decreased 60-70% between birth and the adult period. In the cerebellum, insulin binding doubled in the first 10 postnatal...

journal_title：Developmental neuroscience

authors： Marks JL,Eastman CJ

更新日期：1990-01-01 00:00:00

abstract：:Schizophrenia is a chronic and debilitating mental illness characterized by a broad range of abnormal behaviors, including delusions and hallucinations, impaired cognitive function, as well as mood disturbances and social withdrawal. Due to the heterogeneous nature of the disease, the causes of schizophrenia are very ...

journal_title：Developmental neuroscience

authors： Chew LJ,Fusar-Poli P,Schmitz T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Neonatal hypoxic-ischemic (HI) encephalopathy occurs in 1-4 per 1,000 live term births and can cause devastating neurodevelopmental disabilities. Currently, therapeutic hypothermia (TH) is the only treatment with proven efficacy. Since TH is associated with decreased cerebral metabolism and cerebral blood fl...

journal_title：Developmental neuroscience

authors： Buckley EM,Patel SD,Miller BF,Franceschini MA,Vannucci SJ

更新日期：2015-01-01 00:00:00

abstract：:It has been hypothesized that changes in striatal-mediated dopamine modulation during adolescence may increase the risk for initiating substance abuse as a result of its fundamental role in arbitrating reward sensitivity and motivation during learning and decision making. However, substance abuse during adolescence ma...

journal_title：Developmental neuroscience

authors： Churchwell JC,Carey PD,Ferrett HL,Stein DJ,Yurgelun-Todd DA

更新日期：2012-01-01 00:00:00

abstract：:We have previously shown that a single intracranial injection of apotransferrin (aTf) in neonatal rats produces an accelerated mylinogenesis and increases the expression of certain myelin proteins such as myelin basic protein (MBP). In the present work, we studied the effects of aTf upon oligodendrocyte progenitor cel...

journal_title：Developmental neuroscience

authors： Paez PM,Marta CB,Moreno MB,Soto EF,Pasquini JM

更新日期：2002-01-01 00:00:00

abstract：:The spontaneously immortalized S16 Schwann cell line expresses higher levels of myelin-associated glycoprotein (MAG) and PO glycoprotein and their messenger RNAs when grown at high density than at low density [Sasagasako et al: J Neurochem 1996;66:1432-1439]. This up-regulation of myelin protein expression at high den...

journal_title：Developmental neuroscience

authors： Sasagasako N,Ohno M,Quarles RH

更新日期：1999-01-01 00:00:00

abstract：:Prenatal cocaine exposure results in behavioral abnormalities throughout development in rats, but little is known regarding the biological mechanisms underlying these abnormalities. Pregnant rats received subcutaneous twice-daily injections (1 ml/kg) of normal saline or 15 mg/kg of cocaine hydrochloride throughout ges...

journal_title：Developmental neuroscience

authors： Johns JM,Lubin DA,Lieberman JA,Lauder JM

更新日期：2002-01-01 00:00:00