Expression of nogo-a is decreased with increasing gestational age in the human fetal brain.

abstract：:Neurotoxicological studies have indicated that L-glutamate exhibits more pronounced effects on the preoptic area (POA) neurons of male rats than on those of females in the neonatal period. However, no information has previously been available as to whether or not such sexual dimorphism also exists for the effects of g...

journal_title：Developmental neuroscience

authors： Hsu C,Hsieh YL,Ho ML,Hsu HK,Yu JY

更新日期：2001-01-01 00:00:00

abstract：:In the development of an integrated approach to study metabolic compartmentation and regulation in brain, we have emphasized the importance, versatility, and need to exploit the recent methodological advances in (1) NMR spectroscopy, (2) primary cultures of neurons and glial cells, and (3) subcellular fractionation (e...

journal_title：Developmental neuroscience

authors： Lai JC,Behar KL

更新日期：1993-01-01 00:00:00

abstract：:This study analyzed the role of dopamine D1 and D2 receptors in methylphenidate (MPH) conditioned place preference (CPP) in adolescent male and female rats, in addition to the role of these receptors in the effects of MPH on brain-derived neurotrophic factor (BDNF) in the dorsal striatum and nucleus accumbens. Using a...

journal_title：Developmental neuroscience

authors： Cummins ED,Griffin SB,Duty CM,Peterson DJ,Burgess KC,Brown RW

更新日期：2014-01-01 00:00:00

abstract：:We studied the developmental changes of soluble and membrane-bound protein kinases (EC 2.7.1.37) in rat brain and found that the elution profiles from a DEAE-cellulose column by NaCl of adenosine-3':5'-monophosphate (cyclic AMP) dependent protein kinase from cytosol were not significantly different in newborn (0.19 M ...

journal_title：Developmental neuroscience

authors： Kinnier WJ,Chikvaidze V,Hollenbeck RA,Chuang DM,Costa E

更新日期：1979-01-01 00:00:00

abstract：:Oligodendrocytes from the shiverer mutant mouse are missing most of the myelin basic protein (Mbp) gene. In axon-free cultures, they produce membrane sheets with abnormally assembled microtubule and actin-based structures. This suggests that an Mbp gene product may have an important role in regulating the organization...

journal_title：Developmental neuroscience

authors： Dyer CA,Phillbotte T,Wolf MK,Billings-Gagliardi S

更新日期：1997-01-01 00:00:00

abstract：:We have previously reported that a developmental axon-sparing striatal injury induced by hypoxia-ischemia results in a diminished adult number of substantia nigra (SN) tyrosine hydroxylase (TH)-positive neurons, in the absence of direct nigral injury. To examine the specific role of striatal injury, we made selective ...

journal_title：Developmental neuroscience

authors： Macaya A,Burke RE

更新日期：1992-01-01 00:00:00

abstract：:Preadolescent animals display protracted hormonal stress responses mediated by the hypothalamic-pituitary-adrenal (HPA) axis compared to adults. Though the mechanisms that underlie this shift in stress reactivity are unknown, reduced glucocorticoid-dependent negative feedback on the HPA axis has been posited to contri...

journal_title：Developmental neuroscience

authors： Dziedzic N,Ho A,Adabi B,Foilb AR,Romeo RD

更新日期：2014-01-01 00:00:00

abstract：:We have shown that the developmentally regulated appearance of the two myelin-associated glycoprotein (MAG) polypeptides in normal mouse brain myelin does not reflect the developmental pattern of differential splicing of primary gene transcripts as determined earlier by RNase protection assays. Contrary to expectation...

journal_title：Developmental neuroscience

authors： Braun PE,Horvàth E,Edwards AM

更新日期：1990-01-01 00:00:00

abstract：:A leading hypothesis of the cause of neuronal death in Huntington's disease (HD) is excitotoxicity, in which subpopulations of striatal neurons are hypersensitive to glutamate release due to changes in postsynaptic N-methyl-D-aspartate receptors (NMDARs). In the present study we used RT-PCR methods on single cells and...

journal_title：Developmental neuroscience

authors： Ali NJ,Levine MS

更新日期：2006-01-01 00:00:00

abstract：:Myelinogenesis in different brain parts of trout was studied comparatively by means of histochemistry and biochemistry. A more detailed approach, including ultrastructural analysis, to characterize this important differentiation process, particularly in the optic tectum, revealed a good correlation between the structu...

journal_title：Developmental neuroscience

authors： Jeserich G

更新日期：1981-01-01 00:00:00

abstract：:Stromal-derived factor 1 (SDF-1), a known chemoattractant, and its receptor CXCR4 are widely expressed in the developing and adult cerebral cortex. Recent studies have highlighted potential roles for SDF-1 during early cortical development. In view of the current findings, our histological analysis has revealed a dist...

journal_title：Developmental neuroscience

authors： Liapi A,Pritchett J,Jones O,Fujii N,Parnavelas JG,Nadarajah B

更新日期：2008-01-01 00:00:00

abstract：:Cortex cerebri pieces from fetal donors were homologously and bilaterally grafted to the anterior eye chamber of adult albino rats. After intraocular maturation, presence of an external glial membrane, glial membranes surrounding blood vessels and cortical astrocytes was demonstrated using antisera raised against glia...

journal_title：Developmental neuroscience

authors： Björklund H,Dahl D

更新日期：1982-01-01 00:00:00

abstract：:Adrenoleukodystrophy (ALD) is an X-linked recessive disorder that affects mainly the nervous system white matter and the adrenal cortex. It is associated with an abnormal accumulation of saturated very long chain fatty acids and can be diagnosed by demonstrating an excess of these substances in plasma or red cells. Ou...

journal_title：Developmental neuroscience

authors： Moser HW,Moser AB,Naidu S,Bergin A

更新日期：1991-01-01 00:00:00

abstract：:The fine structure of pituicytes was investigated between 15 days of fetal life and 120 days postnatum. Prior to the penetration of neurosecretory axons into the neural lobe a uniform population of undifferentiated pituicytes is presented. Coincidental with the first appearance of neurosecretory axons in the neural lo...

journal_title：Developmental neuroscience

authors： Dellmann HD,Sikora K

更新日期：1981-01-01 00:00:00

abstract：:Maternal inflammation has been linked to neurodevelopmental and neuropsychiatric disorders such as cerebral palsy, schizophrenia, and autism. We had previously shown that intrauterine inflammation resulted in a decrease in serotonin, one of the tryptophan metabolites, and a decrease in serotonin fibers in the sensory ...

journal_title：Developmental neuroscience

authors： Williams M,Zhang Z,Nance E,Drewes JL,Lesniak WG,Singh S,Chugani DC,Rangaramanujam K,Graham DR,Kannan S

更新日期：2017-01-01 00:00:00

abstract：:In this study we have examined the susceptibility of the mitochondrial respiratory chain of astrocytes and astrocytes depleted of glutathione to peroxynitrite exposure. Astrocytes, as reported previously by us, appeared resistant to the actions of peroxynitrite. In contrast, depletion (-94%) of astrocytic glutathione ...

journal_title：Developmental neuroscience

authors： Barker JE,Bolaños JP,Land JM,Clark JB,Heales SJ

更新日期：1996-01-01 00:00:00

abstract：:Early developmental processes, such as metabolic programming, can provide cues to an organism, which allow it to make modifications that are predicted to be beneficial for survival. Similarly, social play has a multifaceted role in promoting survival and fitness of animals. Play is a complex behavior that is greatly i...

journal_title：Developmental neuroscience

authors： Hehar H,Ma I,Mychasiuk R

更新日期：2016-01-01 00:00:00

abstract：:The myelin-associated glycoprotein (MAG) in primary cultures of oligodendrocytes is subject to phosphorylation in the absence of neurons. The positive response of this phosphorylation to vanadate suggests that one of the modified sites in MAG is phosphotyrosine. We found that phosphorylation was enhanced by brief trea...

journal_title：Developmental neuroscience

authors： Bambrick LL,Braun PE

更新日期：1991-01-01 00:00:00

abstract：:Neurite outgrowth is dependent on the presence in neurites of assembled microtubules which consist of polymerized tubulin to which microtubule-associated proteins (MAPs) are bound. This study adds to previous evidence of the similarity between the high molecular weight MAPs, MAP1X, MAP1B and MAP5, and explains the dif...

journal_title：Developmental neuroscience

authors： Harrison L,Cheetham ME,Calvert RA

更新日期：1993-01-01 00:00:00

abstract：:Insulin binding was measured on crude mitochondrial or plasma membranes prepared from different rat brain regions during postnatal development. In the cerebral cortex and brainstem, insulin binding decreased 60-70% between birth and the adult period. In the cerebellum, insulin binding doubled in the first 10 postnatal...

journal_title：Developmental neuroscience

authors： Marks JL,Eastman CJ

更新日期：1990-01-01 00:00:00

abstract：:The development of the chick bulbar cardiac ganglia has been studied ultrastructurally from the 3rd day of incubation to hatching. For descriptive purposes, their development has been divided into three phases. The first phase includes migration and aggregation of undifferentiated neuroblasts, stages 21-26 (day 3.5-5)...

journal_title：Developmental neuroscience

authors： Kirby ML,Weidman TA,McKenzie JW

更新日期：1980-01-01 00:00:00

abstract：:Developmental expression of neutral monoglycosylceramides (MGCs) has been examined in rat brain from embryonic day 15 (E15) to postnatal day 30 (P30) and adulthood. To this point, glucosylceramide (GlcCer) is the only MGC that has been characterized in embryonic brain. Galactosylceramide (GalCer) appears at P1, increa...

journal_title：Developmental neuroscience

authors： Dasgupta S,Everhart MB,Bhat NR,Hogan EL

更新日期：1997-01-01 00:00:00

abstract：:Rats were exposed to mild hyperoxia and hypoxia by the administration of oxygen/air and nitrogen/air mixtures through plastic tubing held close to their snouts for periods of 3 min. Changes in tissue oxygen were monitored at an implanted carbon paste electrode; local cerebral blood flow (rCBF) at an implanted platinum...

journal_title：Developmental neuroscience

authors： Lowry JP,Demestre M,Fillenz M

更新日期：1998-01-01 00:00:00

abstract：:The auditory system of the cricket has the unusual ability to respond to deafferentation by compensatory growth and synapse formation. Auditory interneurons such as ascending neuron 2 (AN-2) in the cricket Gryllus bimaculatus possess a dendritic arbor that normally grows up to, but not over, the midline of the prothor...

journal_title：Developmental neuroscience

authors： Horch HW,Sheldon E,Cutting CC,Williams CR,Riker DM,Peckler HR,Sangal RB

更新日期：2011-01-01 00:00:00

abstract：:This study investigated the time of expression of two endothelial cell adhesion molecules, ICAM-1/CD54 and PECAM-1/CD31 in the developing postpartum mouse blood-brain barrier (BBB). Immunoultrastructural studies demonstrated that both adhesion molecules are initially expressed primarily on the luminal endothelial cell...

journal_title：Developmental neuroscience

authors： Lossinsky AS,Wisniewski HM

更新日期：1998-01-01 00:00:00

abstract：:The distal segments of the crush-injured and permanently transected sciatic nerve provide models to study Schwann cell activity in the presence and absence of Schwann cell-axonal contact, respectively. We examined the quantity and quality of transcript coding for the myelin-associated glycoprotein (MAG) over a 3-week ...

journal_title：Developmental neuroscience

authors： Gupta SK,Poduslo JF,Dunn R,Roder J,Mezei C

更新日期：1990-01-01 00:00:00

abstract：:Myelin-associated oligodendrocytic basic protein (MOBP) and myelin basic protein (MBP) share many structural similarities. MOBP is synthesised by mature oligodendrocytes and localised at the major dense line (MDL), suggesting a role in the myelin compaction process. The shiverer mouse, a deletion mutant of the myelin ...

journal_title：Developmental neuroscience

authors： Montague P,Kirkham D,McCallion AS,Davies RW,Kennedy PG,Klugmann M,Nave K,Griffiths IR

更新日期：1999-01-01 00:00:00

abstract：:Cultures of rat oligodendrocytes were used to test the possible role of the cerebellar soluble lectin (CSL) in myelin formation. Immunocytochemistry at the ultrastructural level showed that the lectin is present in the cytoplasm of the perikaryon of cultured oligodendrocytes and also on the plasma membrane of the cell...

journal_title：Developmental neuroscience

authors： Kuchler S,Fressinaud C,Sarlieve LL,Vincendon G,Zanetta JP

更新日期：1988-01-01 00:00:00

abstract：:Adult neuronal ceroid lipofuscinosis (NCL), also called Kufs' disease, is clinically distinct from the other NCLs. It is a rare condition which is difficult to diagnose. More than 50% of the reported cases of Kufs' disease are not adult NCL and correspond very likely to a heterogeneous spectrum of lipidoses. Various c...

journal_title：Developmental neuroscience

authors： Martin JJ

更新日期：1991-01-01 00:00:00

abstract：:Nitric oxide (NO) is a recently recognized messenger molecule that has been shown to possess pleiotropic properties, including vasodilation, neurotransmission, cytotoxicity and antimicrobial activity. Constitutive and inducible forms of NO synthase (NOS) have been identified. Activation of cNOS releases relatively low...

journal_title：Developmental neuroscience

authors： Brosnan CF,Battistini L,Raine CS,Dickson DW,Casadevall A,Lee SC

更新日期：1994-01-01 00:00:00