Bilateral consequences of chronic unilateral deafferentation in the auditory system of the cricket Gryllus bimaculatus.

abstract：:Insulin binding was measured on crude mitochondrial or plasma membranes prepared from different rat brain regions during postnatal development. In the cerebral cortex and brainstem, insulin binding decreased 60-70% between birth and the adult period. In the cerebellum, insulin binding doubled in the first 10 postnatal...

journal_title：Developmental neuroscience

authors： Marks JL,Eastman CJ

更新日期：1990-01-01 00:00:00

abstract：:In this study, the proliferative activity of cultured chick neuroblasts exposed to high or low concentrations of fetal calf serum (FCS) was investigated. Different experimental evidences showed that the first 2-3 days of culture correspond to a period of neuronal proliferation in our culture conditions, whereas contam...

journal_title：Developmental neuroscience

authors： Barakat I,Labourdette G,Sensenbrenner M

更新日期：1983-01-01 00:00:00

abstract：:A study was made on the development of cortical synapses in the gracile nucleus of rats using degeneration methods. A total of 46 animals, 1 adult and 45 neonates whose ages varied from 1 to 7 days, had the right somatosensory motor cortex destroyed. The survival period varied from 1 to 30 days. Identification of axon...

journal_title：Developmental neuroscience

authors： Chimelli L,Bello AR,Scaravilli F

更新日期：1994-01-01 00:00:00

abstract：:Cultures of rat oligodendrocytes were used to test the possible role of the cerebellar soluble lectin (CSL) in myelin formation. Immunocytochemistry at the ultrastructural level showed that the lectin is present in the cytoplasm of the perikaryon of cultured oligodendrocytes and also on the plasma membrane of the cell...

journal_title：Developmental neuroscience

authors： Kuchler S,Fressinaud C,Sarlieve LL,Vincendon G,Zanetta JP

更新日期：1988-01-01 00:00:00

abstract：:The L-type calcium channel activator +/-Bay K 8644 has recently been shown to provoke self-injurious biting in young mice. Since the serotonergic systems have been implicated in the expression of self-injurious behavior in both humans and animals, the present studies tested whether drugs influencing serotonin systems ...

journal_title：Developmental neuroscience

authors： Kasim S,Egami K,Jinnah HA

更新日期：2002-01-01 00:00:00

abstract：:The development of the chick bulbar cardiac ganglia has been studied ultrastructurally from the 3rd day of incubation to hatching. For descriptive purposes, their development has been divided into three phases. The first phase includes migration and aggregation of undifferentiated neuroblasts, stages 21-26 (day 3.5-5)...

journal_title：Developmental neuroscience

authors： Kirby ML,Weidman TA,McKenzie JW

更新日期：1980-01-01 00:00:00

abstract：:We have previously shown that a single intracranial injection of apotransferrin (aTf) in neonatal rats produces an accelerated mylinogenesis and increases the expression of certain myelin proteins such as myelin basic protein (MBP). In the present work, we studied the effects of aTf upon oligodendrocyte progenitor cel...

journal_title：Developmental neuroscience

authors： Paez PM,Marta CB,Moreno MB,Soto EF,Pasquini JM

更新日期：2002-01-01 00:00:00

abstract：:Early developmental processes, such as metabolic programming, can provide cues to an organism, which allow it to make modifications that are predicted to be beneficial for survival. Similarly, social play has a multifaceted role in promoting survival and fitness of animals. Play is a complex behavior that is greatly i...

journal_title：Developmental neuroscience

authors： Hehar H,Ma I,Mychasiuk R

更新日期：2016-01-01 00:00:00

abstract：:Early research in the Vannucci laboratory prior to 1981 focused largely on brain energy metabolism in the developing rat. At that time, there was no experimental model to study the effects of perinatal hypoxia-ischemia in the rodent, despite the tremendous need to investigate the pathophysiology of perinatal asphyxial...

journal_title：Developmental neuroscience

authors： Vannucci RC,Vannucci SJ

更新日期：2005-03-01 00:00:00

abstract：:To define the effects of neurotrophins on oligodendrocytes, we monitored NGF, BDNF and NT-3 actions on basal forebrain (BF) and cortical populations. NGF, BDNF and NT-3 applied to BF oligodendrocytes elicited increases in expression of myelin basic protein (MBP) and enhanced the numbers of MBP+ cells, without affectin...

journal_title：Developmental neuroscience

authors： Du Y,Fischer TZ,Lee LN,Lercher LD,Dreyfus CF

更新日期：2003-03-01 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs) originate in multiple restricted regions of the developing central nervous system (CNS). Here, we focus on morphological changes of oligodendrocyte lineage cells and their cellular dynamics including cell motility and proliferation. Morphological studies with molecular markers fo...

journal_title：Developmental neuroscience

authors： Ono K,Kagawa T,Tsumori T,Yokota S,Yasui Y

更新日期：2001-01-01 00:00:00

abstract：:NeuroD is a basic helix-loop-helix (bHLH) transcription factor cloned from a two hybrid screen designed to search for new bHLH proteins. In our previous studies, we showed that NeuroD could convert Xenopus ectoderm into fully differentiated neurons and that it could prematurely differentiate neural precursor cells in ...

journal_title：Developmental neuroscience

authors： Lee JE

更新日期：1997-01-01 00:00:00

abstract：:Plexin is a type I membrane protein which was identified in Xenopus nervous system by hybridoma technique. Molecular cloning studies demonstrated that the extracellular segment of the plexin protein possesses three internal repeats of cysteine cluster which are homologous to the cysteine-rich domain of the c-met proto...

journal_title：Developmental neuroscience

authors： Fujisawa H,Ohta K,Kameyama T,Murakami Y

更新日期：1997-01-01 00:00:00

abstract：:Myelin-associated oligodendrocytic basic protein (MOBP) and myelin basic protein (MBP) share many structural similarities. MOBP is synthesised by mature oligodendrocytes and localised at the major dense line (MDL), suggesting a role in the myelin compaction process. The shiverer mouse, a deletion mutant of the myelin ...

journal_title：Developmental neuroscience

authors： Montague P,Kirkham D,McCallion AS,Davies RW,Kennedy PG,Klugmann M,Nave K,Griffiths IR

更新日期：1999-01-01 00:00:00

abstract：:The fine structure of pituicytes was investigated between 15 days of fetal life and 120 days postnatum. Prior to the penetration of neurosecretory axons into the neural lobe a uniform population of undifferentiated pituicytes is presented. Coincidental with the first appearance of neurosecretory axons in the neural lo...

journal_title：Developmental neuroscience

authors： Dellmann HD,Sikora K

更新日期：1981-01-01 00:00:00

abstract：:Stromal-derived factor 1 (SDF-1), a known chemoattractant, and its receptor CXCR4 are widely expressed in the developing and adult cerebral cortex. Recent studies have highlighted potential roles for SDF-1 during early cortical development. In view of the current findings, our histological analysis has revealed a dist...

journal_title：Developmental neuroscience

authors： Liapi A,Pritchett J,Jones O,Fujii N,Parnavelas JG,Nadarajah B

更新日期：2008-01-01 00:00:00

abstract：:Rabbit central (CNS) and peripheral nervous system (PNS) myelin, as well as nonmyelinating pig oligodendrocytes in culture, were extracted at 0-4 degrees C with the nonionic detergent Triton X-114. The solubilized proteins were partitioned into the detergent-rich and detergent-depleted (aqueous) phases that form upon ...

journal_title：Developmental neuroscience

authors： Bürgisser P,Matthieu JM

更新日期：1989-01-01 00:00:00

abstract：:We have previously shown that lipopolysaccharide (LPS) sensitizes the immature rat brain to subsequent hypoxic-ischemic (HI) injury; however, the underlying mechanisms remain unclear. In this study, we examined the role of glucose in the sensitizing effects of LPS and lipoteichoic acid (LTA) in combination with HI in ...

journal_title：Developmental neuroscience

authors： Eklind S,Arvidsson P,Hagberg H,Mallard C

更新日期：2004-01-01 00:00:00

abstract：:Cerebral metabolism is known to be highly dependent upon glucose utilisation. In the neonate, severe hypoglycaemia is now recognized to be associated with subsequent adverse neurodevelopment and in extremis glial and neuronal cell death. However, the level at which hypoglycaemia becomes clinically important is not wel...

journal_title：Developmental neuroscience

authors： Land JM

更新日期：1994-01-01 00:00:00

abstract：:Primary cultures of cerebellum from 5-day-old rats indicated that proliferating neuroblasts synthesize and release nerve growth factor (NGF). Since NGF promotes DNA synthesis in these cells, our findings demonstrate that the early developing cerebellum is a suitable physiological model for studying the autocrine mitog...

journal_title：Developmental neuroscience

authors： Charrasse S,Jehan F,Confort C,Brachet P,Clos J

更新日期：1992-01-01 00:00:00

abstract：:We investigated the effects of perinatal hypoxia-ischemia (HI) on brain injury and neurological functional outcome at postnatal day (P)30 through P90. HI was induced by exposing P9 mice to 8% O(2) for 55 min using the Vannucci HI model. Following HI, mice were treated with either vehicle control or Na(+)/H(+) exchange...

journal_title：Developmental neuroscience

authors： Cengiz P,Uluc K,Kendigelen P,Akture E,Hutchinson E,Song C,Zhang L,Lee J,Budoff GE,Meyerand E,Sun D,Ferrazzano P

更新日期：2011-01-01 00:00:00

abstract：:In cultured glial cells from chick embryonic brain, both influx and efflux of 42K+ and 22Na+ are dependent on the external Ca++ and concentration ([Ca++]0) between 2 and 0.1 mM although intracellular concentrations of K+ ([K+]i) and Na+ ([Na+]i) do not change. Only a reduction of [Ca++]0 below 0.1 mM results in both a...

journal_title：Developmental neuroscience

authors： Latzkovits L,Rimanóczy A,Juhász A,Torday C,Sensenbrenner M

更新日期：1982-01-01 00:00:00

abstract：:The myelin-associated glycoprotein (MAG) in primary cultures of oligodendrocytes is subject to phosphorylation in the absence of neurons. The positive response of this phosphorylation to vanadate suggests that one of the modified sites in MAG is phosphotyrosine. We found that phosphorylation was enhanced by brief trea...

journal_title：Developmental neuroscience

authors： Bambrick LL,Braun PE

更新日期：1991-01-01 00:00:00

abstract：:Neurite outgrowth is dependent on the presence in neurites of assembled microtubules which consist of polymerized tubulin to which microtubule-associated proteins (MAPs) are bound. This study adds to previous evidence of the similarity between the high molecular weight MAPs, MAP1X, MAP1B and MAP5, and explains the dif...

journal_title：Developmental neuroscience

authors： Harrison L,Cheetham ME,Calvert RA

更新日期：1993-01-01 00:00:00

abstract：:We have shown that the developmentally regulated appearance of the two myelin-associated glycoprotein (MAG) polypeptides in normal mouse brain myelin does not reflect the developmental pattern of differential splicing of primary gene transcripts as determined earlier by RNase protection assays. Contrary to expectation...

journal_title：Developmental neuroscience

authors： Braun PE,Horvàth E,Edwards AM

更新日期：1990-01-01 00:00:00

abstract：:Adult GM2 gangliosidosis is a rare autosomal recessive disease with widely varying neurological and psychiatric manifestations. It is caused by marked deficiency, but not total absence, of beta-hexosaminidase (Hex) A, due to a single base change in the alpha-subunit gene of Hex, resulting in a substitution of Ser for ...

journal_title：Developmental neuroscience

authors： Navon R

更新日期：1991-01-01 00:00:00

abstract：:Birth asphyxia can result in sensory impairment, learning and memory deficits without gross brain injury and severe motor deficits. We developed a model of birth asphyxia resulting in mild neurological injury and cognitive impairment using a long-gestation species with precocial fetal development. Spiny mice (Acomys c...

journal_title：Developmental neuroscience

authors： Hutton LC,Ratnayake U,Shields A,Walker DW

更新日期：2009-01-01 00:00:00

abstract：:Developmental expression of neutral monoglycosylceramides (MGCs) has been examined in rat brain from embryonic day 15 (E15) to postnatal day 30 (P30) and adulthood. To this point, glucosylceramide (GlcCer) is the only MGC that has been characterized in embryonic brain. Galactosylceramide (GalCer) appears at P1, increa...

journal_title：Developmental neuroscience

authors： Dasgupta S,Everhart MB,Bhat NR,Hogan EL

更新日期：1997-01-01 00:00:00

abstract：:Cortex cerebri pieces from fetal donors were homologously and bilaterally grafted to the anterior eye chamber of adult albino rats. After intraocular maturation, presence of an external glial membrane, glial membranes surrounding blood vessels and cortical astrocytes was demonstrated using antisera raised against glia...

journal_title：Developmental neuroscience

authors： Björklund H,Dahl D

更新日期：1982-01-01 00:00:00

abstract：:A leading hypothesis of the cause of neuronal death in Huntington's disease (HD) is excitotoxicity, in which subpopulations of striatal neurons are hypersensitive to glutamate release due to changes in postsynaptic N-methyl-D-aspartate receptors (NMDARs). In the present study we used RT-PCR methods on single cells and...

journal_title：Developmental neuroscience

authors： Ali NJ,Levine MS

更新日期：2006-01-01 00:00:00