Effects of perinatal thyroxine and/or corticosterone treatment on the ontogenesis of hypothalamic and mesencephalic norepinephrine and dopamine content.

abstract：:In the presence of nerve growth factor (NGF) PC12 pheochromocytoma cells develop properties of sympathetic neurons and extend long microtubule-containing neurites. PC12 cell microtubule protein was isolated using an assembly and disassembly procedure, either directly from an unlabeled cell extract or by copolymerizati...

journal_title：Developmental neuroscience

authors： Richter-Landsberg C,Landreth GE,Shooter EM

更新日期：1983-01-01 00:00:00

abstract：:Our previous studies of H218, a sphingosine 1-phosphate (S1P) receptor and a member of the G-protein-coupled receptor superfamily, suggest that it may participate in mammalian nervous system development. Thus, brain levels of H218 mRNA are higher during early neurogenesis than postnatally. In addition, embryonic H218 ...

journal_title：Developmental neuroscience

authors： MacLennan AJ,Devlin BK,Marks L,Gaskin AA,Neitzel KL,Lee N

更新日期：2000-01-01 00:00:00

abstract：:Central nervous system (CNS) stem cells require epidermal growth factor (EGF) to survive and express glial-specific proteins (GSPs) under its influence. EGF and its receptor (EGF-R) therefore are involved in gliogenesis. We hypothesize that EGF selectively modulates GSP expression in pluripotential CNS cells and this ...

journal_title：Developmental neuroscience

authors： Shen YM,Meltzer H,Saljooque F,U HS

更新日期：2001-01-01 00:00:00

abstract：:A glia-derived neurite-promoting factor has been purified from medium conditioned by C6 rat glioma cells. It induces neurite outgrowth in cultured mouse neuroblastoma cells and inhibits granule cell migration in explants of mouse cerebellum. This factor is a potent serine protease inhibitor which has recently been sho...

journal_title：Developmental neuroscience

authors： Zurn AD,Nick H,Monard D

更新日期：1988-01-01 00:00:00

abstract：:The distribution of the noradrenergic system within the rat cerebellar cortex following low-level X-irradiation was studied using tyrosine hydroxylase immunocytochemistry. X-Irradiation treatments consisted of 1, 3, or 5 successive daily dose beginning on postnatal day 1. When studied 24 h after the last exposure, a d...

journal_title：Developmental neuroscience

authors： Kunkler PE,Anderson WJ

更新日期：1994-01-01 00:00:00

abstract：:Although multipotent progenitor cells capable of generating neurons, astrocytes and oligodendrocytes are present within the germinal zones of the brain throughout embryonic, postnatal and adult life, the different neural cell types are generated within discrete temporospatial developmental windows. This might suggest ...

journal_title：Developmental neuroscience

authors： Mehler MF,Mabie PC,Zhu G,Gokhan S,Kessler JA

更新日期：2000-01-01 00:00:00

abstract：:Apoptosis contributes greatly to the morphological and biochemical features of cell death after neonatal cerebral hypoxia-ischemia (HI), making this mode of cell death a promising therapeutic target. We previously showed that 10 mg/kg of the caspase inhibitor Q-VD-OPh at the onset of and immediately after HI on postna...

journal_title：Developmental neuroscience

authors： Han W,Sun Y,Wang X,Zhu C,Blomgren K

更新日期：2014-01-01 00:00:00

abstract：:In some cells, the development of voltage-gated channels requires synaptic input, while in others it does not. Here we investigate whether the sodium and potassium currents in the skeletal muscle of zebrafish sofa potato (sop(-/-)) mutants develop normally. Zebrafish sop(-/-) mutants do not express nicotinic acetylcho...

journal_title：Developmental neuroscience

authors： Coutts CA,Cunningham ME,Ali DW

更新日期：2009-01-01 00:00:00

abstract：:Three experimental approaches were used to examine the maturation of N-methyl-D-aspartate (NMDA) receptors in the neostriatum and compare their developmental profile to that of the non-NMDA receptors [alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and kainate (KA)]. The first, and least conventional ...

journal_title：Developmental neuroscience

authors： Colwell CS,Cepeda C,Crawford C,Levine MS

更新日期：1998-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) have been reported to affect neural stem cell self-renewal and therefore may be important for normal development and may influence neurodegenerative processes when ROS activity is elevated. To determine if increasing production of superoxide, via activation of NADPH oxidase (Nox), increas...

journal_title：Developmental neuroscience

authors： Topchiy E,Panzhinskiy E,Griffin WS,Barger SW,Das M,Zawada WM

更新日期：2013-01-01 00:00:00

abstract：:Choline acetyltransferase (ChAT), the biosynthetic enzyme for acetylcholine metabolism, is expressed in a human cholinergic neuroblastoma cell line; MC-IXC. We demonstrate that ChAT activity is regulated in this cell line by cell density. It is believed that the mechanism of stimulation of enzyme activity involves cel...

journal_title：Developmental neuroscience

authors： Casper D,Davies P

更新日期：1988-01-01 00:00:00

abstract：:The spontaneously immortalized S16 Schwann cell line expresses higher levels of myelin-associated glycoprotein (MAG) and PO glycoprotein and their messenger RNAs when grown at high density than at low density [Sasagasako et al: J Neurochem 1996;66:1432-1439]. This up-regulation of myelin protein expression at high den...

journal_title：Developmental neuroscience

authors： Sasagasako N,Ohno M,Quarles RH

更新日期：1999-01-01 00:00:00

abstract：:Nitric oxide may serve as a retrograde messenger to refine or stabilize synapses in the developing nervous system. Whether this action is dependent upon glutamate and the N-methyl-D-aspartate receptor is not yet established. We have used the patch-cluster system in the intermediate gray layer (IGL) of the rat superior...

journal_title：Developmental neuroscience

authors： Mize RR,Scheiner CA,Salvatore MF,Cork RJ

更新日期：1997-01-01 00:00:00

abstract：:In vertebrate species, the neuropeptide oxytocin (OT) has been implicated in neural and behavioral development. Although several OT-like peptides have been characterized in invertebrate species, the ontogenesis of the OT-like system has not yet been described in these species. Thus, the aim of the present study was to...

journal_title：Developmental neuroscience

authors： Bardou I,Maubert E,Leprince J,Chichery R,Dallérac G,Vaudry H,Agin V

更新日期：2010-03-01 00:00:00

abstract：:The proximodistal axonal transport of choline acetyltransferase (ChAc) has been studied in the chick sciatic nerve in the absence of any experimental manipulation. The phenomenon utilized by us is a physiological transient fall in the activity of ChAc. This fall occurs in most areas of the chick central nervous system...

journal_title：Developmental neuroscience

authors： Giacobini G,Cannas M,Panattoni GL,Filogamo G

更新日期：1979-01-01 00:00:00

abstract：:Maternal inflammation has been linked to neurodevelopmental and neuropsychiatric disorders such as cerebral palsy, schizophrenia, and autism. We had previously shown that intrauterine inflammation resulted in a decrease in serotonin, one of the tryptophan metabolites, and a decrease in serotonin fibers in the sensory ...

journal_title：Developmental neuroscience

authors： Williams M,Zhang Z,Nance E,Drewes JL,Lesniak WG,Singh S,Chugani DC,Rangaramanujam K,Graham DR,Kannan S

更新日期：2017-01-01 00:00:00

abstract：:Early research in the Vannucci laboratory prior to 1981 focused largely on brain energy metabolism in the developing rat. At that time, there was no experimental model to study the effects of perinatal hypoxia-ischemia in the rodent, despite the tremendous need to investigate the pathophysiology of perinatal asphyxial...

journal_title：Developmental neuroscience

authors： Vannucci RC,Vannucci SJ

更新日期：2005-03-01 00:00:00

abstract：:It has been demonstrated that postweaning social isolation alters dendritic development in the medial prefrontal cortex (mPFC) of the rat. In addition, (-)-deprenyl, a monoamine oxidase B (MAO-B) inhibitor, promotes dendritic growth in prefrontocortical pyramidal cells. This study examined whether prefrontocortical de...

journal_title：Developmental neuroscience

authors： Pascual R,Zamora-León SP

更新日期：2007-01-01 00:00:00

abstract：:Previous studies have demonstrated that exposure to ethanol during development delays the rate at which axons in certain central nervous system tracts acquire myelin. This delay appears to be related to an alteration in oligodendrocyte function and not to an aberrancy in axon size or number. The present study was desi...

journal_title：Developmental neuroscience

authors： McNeill DL,Shew RL,Papka RE

更新日期：1991-01-01 00:00:00

abstract：:Using Western blot and immunocytochemistry to detect protein, and in situ hybridization and Northern blot to detect RNA, we studied the expression of Na,K-ATPase subunit isoforms in cultured astrocytes and oligodendrocytes in vitro, and in glial cells in the brain. We found that astrocytes in culture express alpha 1 a...

journal_title：Developmental neuroscience

authors： Fink D,Knapp PE,Mata M

更新日期：1996-01-01 00:00:00

abstract：:Early developmental treatment of rats with 3,4-methylenedioxymethamphetamine (MDMA) was previously found to cause an abnormal pattern of forebrain serotonergic axon density in adulthood consisting of a cortical hypoinnervation and a striatal hyperinnervation. The present study tested the hypothesis that this reorganiz...

journal_title：Developmental neuroscience

authors： Piper BJ,Farelli JD,Meyer JS

更新日期：2009-01-01 00:00:00

abstract：:While extracellular signals play a major role in brain neurogenesis, little is known about the cell cycle machinery underlying mitogen stimulation of precursor proliferation. Current models suggest that the D cyclins function as primary sensors of extracellular mitogens. Here we define the mechanisms by which basic fi...

journal_title：Developmental neuroscience

authors： Li B,DiCicco-Bloom E

更新日期：2004-03-01 00:00:00

abstract：:Rabbit central (CNS) and peripheral nervous system (PNS) myelin, as well as nonmyelinating pig oligodendrocytes in culture, were extracted at 0-4 degrees C with the nonionic detergent Triton X-114. The solubilized proteins were partitioned into the detergent-rich and detergent-depleted (aqueous) phases that form upon ...

journal_title：Developmental neuroscience

authors： Bürgisser P,Matthieu JM

更新日期：1989-01-01 00:00:00

abstract：:When cells from the cerebellum of late-gestation rats were grown at low density (50-100 cells/mm2) in a three-dimensional culture system, they rapidly expressed morphological and electrophysiological properties of neurons. Growth and differentiation of the population of solitary neurons as a whole was statistically as...

journal_title：Developmental neuroscience

authors： Coates PW,Fermini B,Strahlendorf JC,Strahlendorf HK

更新日期：1992-01-01 00:00:00

abstract：:The hippocampal formation is a multicomponent region of the medial temporal lobe preferentially involved in declarative and relational memory processing. Behavioral studies have suggested a protracted functional maturation of these structures in primates, and postnatal developmental abnormalities in the hippocampal fo...

journal_title：Developmental neuroscience

authors： Lavenex P,Banta Lavenex P,Amaral DG

更新日期：2007-01-01 00:00:00

abstract：:Radiotherapy is an effective treatment strategy in the treatment of brain tumors, but it is also a major cause of long-term complications, especially in survivors of pediatric brain tumors. Cognitive decline caused by cranial radiotherapy is thought, at least partly, to depend on injury to stem and progenitor cells in...

journal_title：Developmental neuroscience

authors： Roughton K,Andreasson U,Blomgren K,Kalm M

更新日期：2013-01-01 00:00:00

abstract：:Myelinogenesis in different brain parts of trout was studied comparatively by means of histochemistry and biochemistry. A more detailed approach, including ultrastructural analysis, to characterize this important differentiation process, particularly in the optic tectum, revealed a good correlation between the structu...

journal_title：Developmental neuroscience

authors： Jeserich G

更新日期：1981-01-01 00:00:00

abstract：:Steroid hormones have profound effects on vertebrate behaviors. Yet, in most cases we can neither identify the neurons responsible for particular behaviors nor how steroids alter their excitability. Electric fish emit sexually dimorphic electric organ discharges (EODs) the waveform of which may be altered by steroid t...

journal_title：Developmental neuroscience

authors： Zakon HH

更新日期：1996-01-01 00:00:00

abstract：:Developmental expression of neutral monoglycosylceramides (MGCs) has been examined in rat brain from embryonic day 15 (E15) to postnatal day 30 (P30) and adulthood. To this point, glucosylceramide (GlcCer) is the only MGC that has been characterized in embryonic brain. Galactosylceramide (GalCer) appears at P1, increa...

journal_title：Developmental neuroscience

authors： Dasgupta S,Everhart MB,Bhat NR,Hogan EL

更新日期：1997-01-01 00:00:00

abstract：:The postnatal developmental expression and the distribution of the glutamate transporters (GLAST, GLT-1 and EAAC1) were analyzed in rat vestibular nuclei (VN), at birth and during the following 4 weeks. Analyses were performed using reverse transcriptase-polymerase chain reaction and immunoblotting of GLAST, GLT-1 and...

journal_title：Developmental neuroscience

authors： Devau G,Plachez C,Puyal J,Pierrot N,Ventéo S,Raymond J

更新日期：2003-09-01 00:00:00