The absence of a human thymus lymphocyte antigen (HTLA) on basophils and mast cells.

abstract：:Autologous and allogeneic mixed lymphocyte cultures (AMC and MLC) were assayed for blastogenesis, generation of cytotoxic potential, and the effect of interferon (IFN-alpha) on these features. The cells of the mixed cultures lysed K562, Daudi, and autologous and allogeneic phytohaemagglutinin blasts. Stimulator-specif...

journal_title：Scandinavian journal of immunology

authors： Argov S,Klein E

更新日期：1983-03-01 00:00:00

abstract：:To further investigate the interaction between human mononuclear leucocytes [peripheral blood mononuclear cells (PBMC)] and enterocytes, the effect of a confluent layer of differentiated CACO-2 cells on cytokine kinetics during challenge with bacteria in a compartmentalized coculture model was investigated. Nonpathoge...

journal_title：Scandinavian journal of immunology

authors： Parlesak A,Haller D,Brinz S,Baeuerlein A,Bode C

更新日期：2004-11-01 00:00:00

abstract：:A marked prozone effect was observed in indirect immunofluorescence (IFL) with rabbit antisera against rat renal proximal tubular epithelial brush border (BB) antigens: anti-BB antibodies were not detectable if used in high concentrations but were readily demonstrated if sufficiently diluted. The prozone effect occurr...

journal_title：Scandinavian journal of immunology

authors： Linder E,Miettinen A

更新日期：1976-01-01 00:00:00

abstract：:Cytokines produced by tumour and immune cells may play a significant role in a modulation of immune cells response against tumour. We investigated an ability of peripheral blood mononuclear cells (PBMC) of patients with early and advanced stages of ovarian cancer and from non-cancer patients to produce various cytokin...

journal_title：Scandinavian journal of immunology

authors： Nowak M,Klink M,Glowacka E,Sulowska Z,Kulig A,Szpakowski M,Szyllo K,Tchorzewski H

更新日期：2010-02-01 00:00:00

abstract：:Previous work from our laboratory demonstrated that a synthetic heptapeptide (Ch7: RGSDIAG), corresponding to a conserved sequence of human immunodeficiency virus (HIV) core protein p24 (amino acids 232- 238), was able to specifically abrogate antigen-induced responses in cultures of normal human peripheral blood mono...

journal_title：Scandinavian journal of immunology

authors： Giacomini E,Chersi A,Giordani L,Luzzati AL

更新日期：2000-02-01 00:00:00

abstract：:The effect of trypsin on mouse spleen cells and enriched B cells, added alone or together with lipopolysaccharide (LPS), was investigated. With trypsin, proliferation in serum free spleen cell cultures was 2-6 times greater than the background using cells from LPS responder strains, and 2-4 times the background with c...

journal_title：Scandinavian journal of immunology

authors： Cardell S,Möller G

更新日期：1989-02-01 00:00:00

abstract：:We have depleted lymphocyte subsets in PVG and AO rats with MoAbs 3.2.3 (against NKR-P1 on NK and NK/T cells) and OX-8 (against CD8 on CTL and NK cells), and examined the effect on the killing of YAC-1 target cells in vitro and the effect on the acute rejection of small allogeneic lymphocytes in vivo (allogeneic lymph...

journal_title：Scandinavian journal of immunology

authors： Løvik G,Vaage JT,Rolstad B,Naper C

更新日期：2001-10-01 00:00:00

abstract：:Here we analyse the ability of soluble immune complexes (IC) prepared with cationized antibodies to induce cytotoxic responses mediated by neutrophils. While cationized IC induced high levels of cytotoxicity, control IC induced very low levels of response. Inhibition of cytotoxicity by catalase but not by three haemen...

journal_title：Scandinavian journal of immunology

authors： Geffner JR,Trevani AS,Malchiodi E,Serebrinsky GP,Isturiz MA

更新日期：1993-02-01 00:00:00

abstract：:Chronic inflammatory synovitis is characterized by both lymphocytic infiltrates and persistent polymorph exudates. Activated polymorphs release reactive oxygen species (ROS) during inflammation, but the contribution that these make to the lymphocyte abnormalities associated with RA has been little studied. We therefor...

journal_title：Scandinavian journal of immunology

authors： Allan IM,Lunec J,Salmon M,Bacon PA

更新日期：1987-07-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4) participates in innate immunity by detecting lipopolysaccharides (LPS) of Gram-negative bacterial cell walls. TLR4 macrophage expression in mice is modulated by LPS. This fact constitutes, at least partially, the molecular basis for LPS tolerance. Very recently, the effect of interferon-gam...

journal_title：Scandinavian journal of immunology

authors： Moreno C,Merino J,Vázquez B,Ramírez N,Echeverría A,Pastor F,Sánchez-Ibarrola A

更新日期：2004-06-01 00:00:00

abstract：:T cell immunoglobulin and mucin domain-3 (Tim-3), an immune checkpoint molecule, plays critical roles in maintaining innate immune homeostasis; however, the mechanisms underlying these roles remain to be determined. Here, we determined that Tim-3 controls glycolysis in macrophages and thus contributes to phenotype shi...

journal_title：Scandinavian journal of immunology

authors： Zhang J,Hou C,Dou S,Li G,Wang Z,Liu Y,Zhang Y,Wang R,Shen B,Han G

更新日期：2021-02-01 00:00:00

abstract：:Development of type-II collagen (CII)-induced arthritis (CIA) is dependent on a T-cell mediated activation of autoreactive B cells. However, it is still unclear if B cells can present CII to T cells. To investigate the role of B cells as antigen-presenting cells (APCs) for CII, we purified B cells from lymph nodes of ...

journal_title：Scandinavian journal of immunology

authors： Holmdahl M,Vestberg M,Holmdahl R

更新日期：2002-04-01 00:00:00

abstract：:In a previous report the authors demonstrated that acute graft-versus-host disease (GVHD) was associated with pathologic amounts of tumour necrosis factor alpha (TNF-alpha) and the appearance of lipopolysaccharide (LPS) in the blood of GVH reactive mice just prior to death. In this study the authors have investigated ...

journal_title：Scandinavian journal of immunology

authors： Price KS,Nestel FP,Lapp WS

更新日期：1997-03-01 00:00:00

abstract：:Transgenic techniques in inbred mouse strains are powerful tools to investigate the specific roles of genes in biological pathways and disease models. However, there is increasing concern over the influence of a variable genetic background in such experiments. To date there have been few investigations of the immunolo...

journal_title：Scandinavian journal of immunology

authors： Johansson AC,Vestberg M,Holmdahl R

更新日期：2000-07-01 00:00:00

abstract：:In this study, we discuss the use of glycopeptides containing tumour-associated carbohydrate antigens (TACA) as preventive vaccines for carcinomas. The results of our recent studies suggest that CD8(+) cytotoxic T cells are capable of recognizing small TACA in a conventional class I MHC-restricted fashion. TACA-specif...

journal_title：Scandinavian journal of immunology

authors： Franco A

更新日期：2005-05-01 00:00:00

abstract：:Interleukin-1 (IL-1) production by the human monocyte-like cloned cell line CM-SM has been investigated as a function of the state of cell differentiation. CM-SM cells were induced to differentiate along the monocyte-macrophage lineage by bacterial lipopolysaccharides (LPS) or by 12-O-tetradecanoyl-phorbol-13-acetate ...

journal_title：Scandinavian journal of immunology

authors： Revoltella RP,Butler RH,Musiani P,Piantelli M,Ranelletti FO

更新日期：1985-01-01 00:00:00

abstract：:In this review, we summarize and discuss some key findings from the study of naturally occurring autoantibodies. The B-cell compartment of the immune system appears to recognize almost all endogenous and environmental antigens. This ability is accomplished principally through autopolyreactive humoral and cellular immu...

journal_title：Scandinavian journal of immunology

authors： Avrameas S

更新日期：2016-04-01 00:00:00

abstract：:The aim of the present study was to present further evidence of the specific reactivity of an anti-C3 receptor serum (AC3RS), to demonstrate membrane-bound C3 receptors by using this AC3RS in different serological an immunohistological methods, and to investigate the relationship between membrane-bound C3 receptors an...

journal_title：Scandinavian journal of immunology

authors： Stein H,Gerdes J,Tolksdorf G,Klatt U

更新日期：1981-01-01 00:00:00

abstract：:This study describes Leishmania antigen-induced activation of lymphocytes isolated from Kenyan donors, previously treated for visceral leishmaniasis, and from Danish and Kenyan controls. Peripheral blood mononuclear cells (PBMC) from cured Kala-Azar patients proliferated and produced Interferon-gamma in vitro in respo...

journal_title：Scandinavian journal of immunology

authors： Kemp M,Theander TG,Handman E,Hey AS,Kurtzhals JA,Hviid L,Sørensen AL,Were JO,Koech DK,Kharazmi A

更新日期：1991-02-01 00:00:00

abstract：:Administration of cyclophosphamide (Cy: 150 mg/kg i.p.) to rats 48 h before immunization with a T-dependent antigen (ovalbumin) resulted in a striking absolute eosinophilia in blood, bone marrow, and secondary lymphoid organs after 10 to 14 days. This eosinophilia was preceded by a significant increase in the W3/25+/O...

journal_title：Scandinavian journal of immunology

authors： Mathie IH,Sewell HF,Thomson AW

更新日期：1987-10-01 00:00:00

abstract：:The binding of a 34-kDa (mol. wt.) acylpoly(1,3)galactoside (APG) extracted from a membrane proteoglycan of Klebsiella pneumoniae to human blood leucocytes was investigated. APG is made of a long poly(1,3)galactose chain, a core-like region and a lipid moiety which comprises two glucosamine residues bound to a phospha...

journal_title：Scandinavian journal of immunology

authors： Hmama Z,Kouassi E,Panaye G,Delassan S,Normier G,Binz H,Revillard JP

更新日期：1992-07-01 00:00:00

abstract：:In all of four human germinal centre cell-associated B lymphomas carrying sIgM + sIgD F(ab')2 fragments of rabbit antibodies to human mu-chain were accumulated intracellularly, whereas the accumulation of antibodies to delta-chain was considerably less abundant. The accumulation of antibodies to light chain was interm...

journal_title：Scandinavian journal of immunology

authors： Ruud E,Beiske K,Drack A,Steen HB,Godal T

更新日期：1984-05-01 00:00:00

abstract：:Chromosomally marked cells from the 7-day intraembryonic mesenchyme were transplanted into 14-day-old irradiated chick embryos. At the age of 6 weeks donor-derived T and B lymphocytes were shown to be present in the thymus, spleen and bone marrow, indicating that cells in the 7-day intraembryonic mesenchyme are capabl...

journal_title：Scandinavian journal of immunology

authors： Lassila O,Eskola J,Toivanen P,Dieterlen-Lièvre F

更新日期：1980-01-01 00:00:00

abstract：:Previously reported experiments suggested that an esterase or a protease, or both, might participate in the expression of human leukocyte migration inhibitory factor (LIF). To clarify this further, a wide variety of simple ester were tested for the ability to protect LIF against inactivation by the serine esterase inh...

journal_title：Scandinavian journal of immunology

authors： Bendtzen K

更新日期：1977-01-01 00:00:00

abstract：:Ficolin-2 (L-ficolin), derived from the FCN2 gene, is an innate immunity pattern recognition molecule found in human serum in which inter-individual variation in serum appears to be under genetic control. To validate and extend this finding, we developed a sandwich ELISA for detection of human Ficolin-2 in serum sampl...

journal_title：Scandinavian journal of immunology

authors： Munthe-Fog L,Hummelshøj T,Hansen BE,Koch C,Madsen HO,Skjødt K,Garred P

更新日期：2007-04-01 00:00:00

abstract：:Leukaemic blood lymphocytes from a patient in the terminal stage of chronic lymphocytic leukaemia (CLL) according to the Kiel classification were stimulated by lipopolysaccharide from Escherichia coli. During progression to blast transformation, stimulated cells lost receptors for mouse erythrocytes (MRBC), accumulate...

journal_title：Scandinavian journal of immunology

authors： Robèrt KH,Juliusson G,Biberfeld P

更新日期：1983-05-01 00:00:00

abstract：:Human CD26 has dipeptidyl peptidase-4 (DPP IV) enzyme activity and binds to adenosine deaminase (ADA). CD26 is costimulatory for lymphocytes and has a circulating soluble form (sCD26). DPP IV enzyme inhibition is a new successful type 2 diabetes therapy. We examined whether the ADA binding and catalytic functions of s...

journal_title：Scandinavian journal of immunology

authors： Yu DM,Slaitini L,Gysbers V,Riekhoff AG,Kähne T,Knott HM,De Meester I,Abbott CA,McCaughan GW,Gorrell MD

更新日期：2011-02-01 00:00:00

abstract：:Granulomatous lymphomatosis is an Epstein-Barr virus (EBV)-driven B cell proliferation associated with an exuberant CD4(+) T cell reaction with usually histopathological pictures of angiocentrism. So far, the characteristics of CD4(+) T cells in granulomatous lymphomatosis and the mechanism leading to their expansion ...

journal_title：Scandinavian journal of immunology

authors： Cervera P,Guihot A,Gorochov G,Lassoued K,Coppo P

更新日期：2015-12-01 00:00:00

abstract：:The reactivity of rabbit anti-HLA-DR antigen antibodies with cells in normal and rheumatoid synovial tissue was investigated by indirect immunofluorescence on frozen sections of tissue. The antibodies reacted with a significant proportion of the synovial lining cells of both normal and rheumatoid synovial tissue, with...

journal_title：Scandinavian journal of immunology

authors： Klareskog L,Forsum U,Malmnäs Tjernlund UK,Kabelitz D,Wigren A

更新日期：1981-08-01 00:00:00

abstract：:Guinea pig alpha 1-microglobulin (alpha 1-m) was found to exert mitogenic effects on guinea pig lymphocytes, i.e. peritoneal exudate lymphocytes (PEL) or T lymphocytes from regional or mesenteric lymph nodes (LNL). On the other hand, spleen T lymphocytes did not respond to alpha 1-m. Stimulation of LNL required the pr...

journal_title：Scandinavian journal of immunology

authors： Lögdberg L,Akerström B,Shevach EM

更新日期：1986-11-01 00:00:00