Different fate of antibodies to surface IgM and IgD in germinal centre cell-associated lymphomas.

abstract：:Inflammatory DCM (iDCM) may be related to autoimmune processes. An immunoadsorption (IA) has been reported to improve cardiac hemodynamics. The benefit of IA is probably related to the removal of autoantibodies. A recent study suggests additional effects of IA on the T cell-mediated immune reactions, especially on reg...

journal_title：Scandinavian journal of immunology

authors： Bulut D,Creutzenberg G,Mügge A

更新日期：2013-01-01 00:00:00

abstract：:The effect of trypsin on mouse spleen cells and enriched B cells, added alone or together with lipopolysaccharide (LPS), was investigated. With trypsin, proliferation in serum free spleen cell cultures was 2-6 times greater than the background using cells from LPS responder strains, and 2-4 times the background with c...

journal_title：Scandinavian journal of immunology

authors： Cardell S,Möller G

更新日期：1989-02-01 00:00:00

abstract：:Immunoglobulin-secreting cells (ISC) in the peripheral blood of healthy individuals and in the bone marrow, peripheral blood, or plasmacytomas of patients with multiple myeloma were enumerated by a protein-A plaque-forming cell assay after treatment with anti-Ia antibody and complement. Rabbit anti-human B-cell antise...

journal_title：Scandinavian journal of immunology

authors： Nagai K,Nagai T,Takatsuki K,Uchino H

更新日期：1982-06-01 00:00:00

abstract：:T cells from immune guinea-pigs produce clusters in vitro with macrophages pulsed with soluble protein antigens. The formation of clusters is antigen-specific. Time-lapse cinephotomicrography was used to study the sequence of events leading to cluster formation and the kinetics of already formed clusters. The central ...

journal_title：Scandinavian journal of immunology

authors： Petri J,Braendstrup O,Werdelin O

更新日期：1979-01-01 00:00:00

abstract：:The enhancement of the lytic capacity of mouse splenic 'natural killer' (NK) cells by interferon has been studied in vitro as a model for NK cell differentiation from inactive immediate precursors. We show that the increased cytotoxicity is a function of interferon concentration, and that two stages in the NK cell dif...

journal_title：Scandinavian journal of immunology

authors： Senik A,Kolb JP,Orn A,Gidlund M

更新日期：1980-01-01 00:00:00

abstract：:The in vitro anti-trinitrophenyl (TNP) response induced by TNP-lipopolysaccharide (TNP-LPs) in mouse spleen cells was eliminated by passage through Sephadex G10 columns. Conditioned medium obtained from peritoneal macrophages restored the response, indicating the supportive role of such cells in the response. Converse...

journal_title：Scandinavian journal of immunology

authors： Martinez-Alonso C,Bernabe RR,Diaz-Espada F

更新日期：1980-01-01 00:00:00

abstract：:Chromosomally marked cells from the 7-day intraembryonic mesenchyme were transplanted into 14-day-old irradiated chick embryos. At the age of 6 weeks donor-derived T and B lymphocytes were shown to be present in the thymus, spleen and bone marrow, indicating that cells in the 7-day intraembryonic mesenchyme are capabl...

journal_title：Scandinavian journal of immunology

authors： Lassila O,Eskola J,Toivanen P,Dieterlen-Lièvre F

更新日期：1980-01-01 00:00:00

abstract：:Rheumatoid arthritis synovial fluid (RA-SF) contains a distinct biological activity that selectively induces IgG2b production in LPS-activated murine B blasts. This IgG2b inducing factor (IgG2bIF) acts directly on purified LPS-activated B blasts from normal and Bruton's tyrosine kinase-defective CBA/N mice. In order t...

journal_title：Scandinavian journal of immunology

authors： Lettesjö H,Ridderstad A,Möller E

更新日期：1997-01-01 00:00:00

abstract：:Gαq, the alpha subunit of Gq, a member of the Gq/11 sub-family, was reported to inhibit phosphatidylinositol-3-Kinase (PI3K) activation and prevent the activation of Akt. Previous studies demonstrated that mice losing Gαq in their immune system could spontaneously develop inflammatory arthritis. In this study, we show...

journal_title：Scandinavian journal of immunology

authors： Wang Y,Li Y,He Y,Sun Y,Sun W,Xie Q,Yin G,Du Y,Wang L,Shi G

更新日期：2012-02-01 00:00:00

abstract：:Using rocket immunoelectrophoresis and indirect haemagglutination tests, antibodies to nicotinic acetylcholine receptor (n-AChR) from Torpedo marmorata were detected in sera from rabbits with experimental myasthenia but not in sera from patients with myasthenia gravis or in rabbit antisera to a partly purified skeleta...

journal_title：Scandinavian journal of immunology

authors： Aarli JA,Mattsson C,Heilbronn E

更新日期：1975-01-01 00:00:00

abstract：:Oral vaccination with the combined B subunit/whole cell cholera vaccine generates antitoxin memory cells that could be isolated from peripheral blood for at least 1 year after immunization. These memory cells were triggered by antigen in vitro to produce antitoxin in the presence of autologous T cells and monocytes. A...

journal_title：Scandinavian journal of immunology

authors： Lycke N,Hellström U,Holmgren J

更新日期：1987-08-01 00:00:00

abstract：:The human serum amyloid A (SAA) gene family consists of two acute phase genes, SAA1 and SAA2; a pseudogene, SAA3 and a fourth gene, SAA4. The existence of SAA4 was first described in this laboratory. Subsequently, Sack & Talbot isolated a clone, designated GSAA4, which had homology to SAA3. The clone was described as ...

journal_title：Scandinavian journal of immunology

authors： Watson G,Faulkes DJ,Woo P

更新日期：1994-08-01 00:00:00

abstract：:Here we analyse the ability of soluble immune complexes (IC) prepared with cationized antibodies to induce cytotoxic responses mediated by neutrophils. While cationized IC induced high levels of cytotoxicity, control IC induced very low levels of response. Inhibition of cytotoxicity by catalase but not by three haemen...

journal_title：Scandinavian journal of immunology

authors： Geffner JR,Trevani AS,Malchiodi E,Serebrinsky GP,Isturiz MA

更新日期：1993-02-01 00:00:00

abstract：:Analysis of seven variable-diversity-joining (VDJ) gene rearrangements in B splenocytes from a 125-day-old bovine foetus revealed an extensive heavy-chain complementarity-determining region 3 (CDR3H) length variation (9-56 codons). Indeed, the global CDR3H size spectratyping of foetal VDJ rearrangements substantiated ...

journal_title：Scandinavian journal of immunology

authors： Saini SS,Kaushik A

更新日期：2002-02-01 00:00:00

abstract：:During immunological rejection of the transplanted heart, cytotoxic T lymphocytes (CTL) infiltrate the myocardium and by damaging the myocytes contribute to loss of function. To address one important aspect of heart transplant rejection, we investigated in guinea pig ventricular myocytes how CTL-derived lytic granules...

journal_title：Scandinavian journal of immunology

authors： Binah O,Kline R,Berke G,Hoffman B

更新日期：1993-01-01 00:00:00

abstract：:There is convincing evidence that certain combinations of alleles within the human leucocyte antigen (HLA) complex, particularly within HLA-DQ, are associated with either resistance or susceptibility to insulin-dependent diabetes mellitus (IDDM). A previous study conducted on a large, well-defined group of patients de...

journal_title：Scandinavian journal of immunology

authors： Baisch JM,Capra JD

更新日期：1992-08-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) preparations have been shown to suppress lymphocyte proliferation in vitro. This study aimed to investigate the effects of an IVIG produced by fractionation/DEAE-Sephadex adsorption on lymphocyte proliferation in vitro, with particular reference to contributions of the stabilizing age...

journal_title：Scandinavian journal of immunology

authors： Alder LB,Morgan LA,Spickett GP

更新日期：1996-12-01 00:00:00

abstract：:Macrophages altered by various Th2-associated and anti-inflammatory mediators--including IL-4 and IL-13 [inducing alternatively activated macrophages (AAMs)], IL-10 and TGF-β--were generically termed M2. However, markers that discriminate between AAMs and other M2 remain scarce. We previously described E-cadherin as a...

journal_title：Scandinavian journal of immunology

authors： Van den Bossche J,Laoui D,Morias Y,Movahedi K,Raes G,De Baetselier P,Van Ginderachter JA

更新日期：2012-06-01 00:00:00

abstract：:The immune system produces specific antibodies (Ab) against any antigens (Ag) of exogenous and endogenous origins with a diverse repertoire of V-region specificities. The primary V-region repertoire is created by the rearrangement of immunoglobulin (Ig) V-region, D- and J-segments with the insertion of N- and P-sequen...

journal_title：Scandinavian journal of immunology

authors： Sakaguchi N,Maeda K,Kuwahara K

更新日期：2011-06-01 00:00:00

abstract：:BTK and ITK are cytoplasmic tyrosine kinases of crucial importance for B and T cell development, with loss-of-function mutations causing X-linked agammaglobulinemia and susceptibility to severe, frequently lethal, Epstein-Barr virus infection, respectively. Over the last few years, considerable efforts have been made ...

journal_title：Scandinavian journal of immunology

authors： Vargas L,Hamasy A,Nore BF,Smith CI

更新日期：2013-08-01 00:00:00

abstract：:Bacterial DNA differs from mammalian DNA by the presence of unmethylated cytosine-phosphate-guanosine (CpG) motifs. The immunostimulatory properties of a DNA vaccine have been suspected to be associated with these motifs. The aim of this study was to assess the inactivation of the immunostimulatory potential of a plas...

journal_title：Scandinavian journal of immunology

authors： Cornélie S,Poulain-Godefroy O,Lund C,Vendeville C,Ban E,Capron M,Riveau G

更新日期：2004-02-01 00:00:00

abstract：:Thalidomide is well documented to be an effective treatment for erythema nodosum leprosum (ENL) occurring in lepromatous leprosy. To be beneficial, thalidomide must interfere with one or more of the several essential steps in the pathogenesis of this syndrome, which is presumed to be a clinical manifestation of an Art...

journal_title：Scandinavian journal of immunology

authors： Shannon EJ,Miranda RO,Morales MJ,Hastings RC

更新日期：1981-01-01 00:00:00

abstract：:Leukaemic blood lymphocytes from a patient in the terminal stage of chronic lymphocytic leukaemia (CLL) according to the Kiel classification were stimulated by lipopolysaccharide from Escherichia coli. During progression to blast transformation, stimulated cells lost receptors for mouse erythrocytes (MRBC), accumulate...

journal_title：Scandinavian journal of immunology

authors： Robèrt KH,Juliusson G,Biberfeld P

更新日期：1983-05-01 00:00:00

abstract：:The predominant selection of CRI-A-bearing antibodies during the anti-arsonate (ARS) response of A/J mice has been used as a model to analyse the mechanism involved in the process of clonal selection and establishment of predominance. In order to assess the importance of the affinity and adaptability of CRI-A clones i...

journal_title：Scandinavian journal of immunology

authors： Gaya A,Alsinet E,Freixas M,Vives J

更新日期：1988-09-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection is a risk factor for thrombotic microangiopathy (TMA). We sought whether a severe deficiency in ADAMTS13, the enzyme specifically involved in the cleavage of von Willebrand factor, was associated with specific presenting features and outcome in HIV-associated TMA. In this p...

journal_title：Scandinavian journal of immunology

authors： Malak S,Wolf M,Millot GA,Mariotte E,Veyradier A,Meynard JL,Korach JM,Malot S,Bussel A,Azoulay E,Boulanger E,Galicier L,Devaux E,Eschwège V,Gallien S,Adrie C,Schlemmer B,Rondeau E,Coppo P,Réseau d'Etude des Microangi

更新日期：2008-09-01 00:00:00

abstract：:In vitro lymphocyte stimulation was performed on peripheral blood lymphocytes from 48 leprosy patients, 15 healthy contacts of leprosy patients, and 16 normal controls who lived in a leprosy-free area and who had not been exposed to leprosy. Tuberculin PPD and an antigen fraction. MLW 1, prepared from M. leprae, were ...

journal_title：Scandinavian journal of immunology

authors： Closs O,Reitan LJ,Negassi K,Harboe M,Belehu A

更新日期：1982-08-01 00:00:00

abstract：:Approximately 70% of kidney transplant recipients are non-responders to conventional hepatitis B virus (HBV) vaccines. We examined whether Fendrix™, an HBV vaccine containing 3-O-desacyl-4'-monophosphoryl lipid A (MPL) as adjuvant, could induce HBV immunity in these patients and compared their vaccination efficacy wit...

journal_title：Scandinavian journal of immunology

authors： Lindemann M,Zaslavskaya M,Fiedler M,Wilde B,Heinemann FM,Heinold A,Horn PA,Witzke O

更新日期：2017-01-01 00:00:00

abstract：:Fenugreek is a legume mostly used as a spice in Indian-style cooking. Although it has been used since ancient times, its allergenicity has only been reported in the last two decades. It poses special problems as an emerging and often hidden allergen. Fenugreek exposure may have serious implications also for individual...

journal_title：Scandinavian journal of immunology

authors： Vinje NE,Namork E,Løvik M

更新日期：2011-10-01 00:00:00

abstract：:Understanding the specificity of antibody response to Neisseria meningitidis serogroup B (Men B) is a key requirement for the development of an effective vaccine. This study was designed to investigate the antigen specificity of murine IgG1 and IgG2b antibodies induced by different primary immunization schedules and t...

journal_title：Scandinavian journal of immunology

authors： Silva Junior FC,Gioia CA,Oliveira JM,Cruz SC,Frasch CE,Milagres LG

更新日期：2007-01-01 00:00:00

abstract：:Non-specific antibody production usually accompanies the T-cell-regulated B-cell response. In this paper the mechanisms involved in non-MHC-restricted T-B-cell interaction were studied. As previously shown for NK cells, activated B cells induce IFN-gamma and TNF alpha production in non-MHC-restricted cytotoxic T lymph...

journal_title：Scandinavian journal of immunology

authors： Becker JC,Dummer R,Von Wussow P,Burg G,Schmidt RE

更新日期：1992-08-01 00:00:00