Abstract：
:The ability of different calcium phosphate to activate the complement system is studied by crossed immunoelectrophoresis demonstrating conversion of C3 to C3b. Complement consumption is determined by a haemolytic assay CH50. Hydroxyapatite powders after sintering induce a significant conversion of C3 and reduction of CH50 value. However the complement system is not activated by sintered tricalciumphosphate (beta-whitlockite). This is not related to the adsorption behaviour; it depends neither on chemical composition nor on crystal lattice. It is argued that C3 conversion is not triggered by the convertase of the classical pathway.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Klein CP,de Groot K,van Kamp Gdoi
10.1016/0142-9612(83)90007-8subject
Has Abstractpub_date
1983-07-01 00:00:00pages
181-4issue
3eissn
0142-9612issn
1878-5905pii
0142-9612(83)90007-8journal_volume
4pub_type
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