Synthesis and properties of amphiphilic networks. 1: the effect of hydration and polymer composition on the adhesion of immunoglobulin-G to poly(laurylmethacrylate-stat-glycerolmonomethacrylate-stat-ethylene-gly col-dimethacrylate) networks.

abstract：:A procedure for preparing homogeneous chitosan gels by in situ molybdate cross-linking is described. The gels are obtained by dispersing solid MoO3 in a buffered chitosan solution and the polymer is cross-linked by formation of heavily negatively charged molybdate polyoxyanions. The resulting ionic gels are very trans...

journal_title：Biomaterials

authors： Draget KI,Vårum KM,Moen E,Gynnild H,Smidsrød O

更新日期：1992-01-01 00:00:00

abstract：:By use of scanning electron microscopy (SEM), together with energy dispersive chemical analysis, a study has been made of the comparison of an in vitro method of assessing interface reactions between bone and ceramic implants with the naturally occurring changes seen in the rat ear model. Interface reactions between b...

journal_title：Biomaterials

authors： Williams KR,Blayney AW,Frootko NJ,Ashton BA

更新日期：1985-07-01 00:00:00

abstract：:In order to evaluate degradation kinetics and biocompatibility of a resorbable poly(D,L-lactic acid) (PDLLA) plug for total cemented hip prostheses, an experimental in vitro and in vivo study was carried out. Degradation rate studies were performed in Ringer solution and after in vivo plug implantation in the femoral ...

journal_title：Biomaterials

authors： Giardino R,Fini M,Aldini NN,Giavaresi G,Rocca M,Orienti L,de Lollis A,Fambri L

更新日期：1997-07-01 00:00:00

abstract：:The necessity of information about the inner microscopical features of low absorbing materials is one of the most important goals in the structural research field. So far, non destructive analysis have been performed using contact radiography giving the scope for great advances in the production and application of new...

journal_title：Biomaterials

authors： Baruchel J,Lodini A,Romanzetti S,Rustichelli F,Scrivani A

更新日期：2001-06-01 00:00:00

abstract：:Biodegradable and pH-sensitive hydrogels containing azoaromatic moieties were synthesized from the same polymeric precursors by two synthetic methods, namely a polymer-polymer reaction and cross-linking of polymeric precursors. The effect of the synthetic route employed and the detailed network structure on in vitro d...

journal_title：Biomaterials

authors： Ghandehari H,Kopecková P,Kopecek J

更新日期：1997-06-01 00:00:00

abstract：:This study aimed to assess the biocompatibility of two cordierite ceramics (DF and Cord 1014), with similar chemical composition and different porosity, as a potential support for cell growth in a continuous-flow, solid-bed reactor. The Chinese hamster ovary (CHO) cell line transfected with HBV-DHFR recombinant plasmi...

journal_title：Biomaterials

authors： Orlandi L,Solmi R,Krajewski A,Bearzatto A,Biagini G,Ciccopiedi E,Ravaglioli A

更新日期：1997-07-01 00:00:00

abstract：:Human stem cells are vulnerable to unfavorable conditions, and their transportation relies on costly and inconvenient cryopreservation. We report here that human mesenchymal stem cells (MSC) in spheroids survived ambient conditions (AC) many days longer than in monolayer. Under AC, the viability of MSC in spheroids re...

journal_title：Biomaterials

authors： Jiang B,Yan L,Miao Z,Li E,Wong KH,Xu RH

更新日期：2017-07-01 00:00:00

abstract：:The effect of surface characteristics on the interaction of sterically stabilized polystyrene particles with mouse peritoneal macrophages was studied using a range of poloxamers and poloxamine as coating agents. The coated particles were characterized in terms of thickness of coating layer, surface charge and critical...

journal_title：Biomaterials

authors： Illum L,Jacobsen LO,Müller RH,Mak E,Davis SS

更新日期：1987-03-01 00:00:00

abstract：:Particle-associated periprosthetic osteolysis remains a major issue in joint replacement. Ongoing bone loss resulting from wear particle-induced inflammation is accompanied by continued attempts at bone repair. Previously we showed that mesenchymal stem cells (MSCs) are recruited systemically to bone exposed to contin...

journal_title：Biomaterials

authors： Gibon E,Yao Z,Rao AJ,Zwingenberger S,Batke B,Valladares R,Smith RL,Biswal S,Gambhir SS,Goodman SB

更新日期：2012-05-01 00:00:00

abstract：:Effects of squalane-dissolved fullerene-C60 (Sql-fullerene) on macrophage activation and adipose conversion with oxidative stress were studied using an inflammatory adipose-tissue equivalent (ATE) and OP9 mouse stromal preadipocyte-U937 lymphoma cell co-culture systems. Differentiation of OP9 cells was initiated by in...

journal_title：Biomaterials

authors： Xiao L,Aoshima H,Saitoh Y,Miwa N

更新日期：2010-08-01 00:00:00

abstract：:Although transplantation of pancreatic islets is a promising approach for treatment of type 1 diabetes mellitus, the engraftment efficiency of these islets is limited by host immune responses. Extensive efforts have been made to immunoisolate these islets by introducing barriers on the islet surface. To date, these ba...

journal_title：Biomaterials

authors： Izadi Z,Hajizadeh-Saffar E,Hadjati J,Habibi-Anbouhi M,Ghanian MH,Sadeghi-Abandansari H,Ashtiani MK,Samsonchi Z,Raoufi M,Moazenchi M,Izadi M,Nejad ASSH,Namdari H,Tahamtani Y,Ostad SN,Akbari-Javar H,Baharvand H

更新日期：2018-11-01 00:00:00

abstract：:Increasing knowledge about molecular mechanisms of endogenous RNA interference (RNAi) and small interfering RNAs (siRNAs) has been incorporated into innovative nucleic acid medicines for treatment of diseases such as cancers. Although RNAi and siRNA have the potential to become powerful therapeutic drugs, their delive...

journal_title：Biomaterials

authors： Kesharwani P,Gajbhiye V,Jain NK

更新日期：2012-10-01 00:00:00

abstract：:It has been demonstrated that using cultured chondrocytes that have been seeded onto various biomatrices can enhance the quality of the articular cartilage repair tissue. As tissue-engineering becomes increasingly more complex there is a need to understand how a specific biomaterial may influence gene expression. In t...

journal_title：Biomaterials

authors： Saldanha V,Grande DA

更新日期：2000-12-01 00:00:00

abstract：:This paper completes the model of biodegradation for biodegradable polymers that was previously developed by Wang et al. (Wang Y, Pan J, Han X, Sinka, Ding L. A phenomenological model for the degradation of biodegradable polymers. Biomaterials 2008;29:3393-401). Crystallisation during biodegradation was not considered...

journal_title：Biomaterials

authors： Han X,Pan J

更新日期：2009-01-01 00:00:00

abstract：:Hypoxia, as an inevitable characteristic of solid tumors, has been regarded as a noticeably causative factor to therapeutic resistance and metastatic variants. Exploring novel theranostics to realize the accurate diagnosis of hypoxia and the simultaneous implementation of effective therapy is a promising prospect for ...

journal_title：Biomaterials

authors： Song R,Zhang M,Liu Y,Cui Z,Zhang H,Tang Z,Chen X,Wu H,Yao Z,He M,Bu W

更新日期：2018-08-01 00:00:00

abstract：:Layered double hydroxide (LDH) nanoparticles are attractive as potential drug vectors for the targeting not only of tissues, but also of intracellular organelles, and particularly the acidic endolysosomes created after cell endocytosis. The purpose of this study was to investigate the ability of LDH nanoparticles desi...

journal_title：Biomaterials

authors： Li A,Qin L,Zhu D,Zhu R,Sun J,Wang S

更新日期：2010-02-01 00:00:00

abstract：:The development of synthetic hydrogels analogs for the extracellular matrix has proven a useful and important tool to study the role of specific signals on biological outcomes in vitro and to serve as scaffolds for tissue repair. Although the importance of physical properties (e.g. microstructure and stiffness) in the...

journal_title：Biomaterials

authors： Darling NJ,Hung YS,Sharma S,Segura T

更新日期：2016-09-01 00:00:00

abstract：:The adsorption of chondroitin-4-sulphate (C4S) and heparin onto titanium has been studied in the absence and presence of bovine serum albumin (BSA). Isotherm data (0.02 M calcium acetate, pH 6.8) have shown that BSA in solution and BSA-coated titanium result in decreased adsorption for both C4S and heparin. For the BS...

journal_title：Biomaterials

authors： Hughes Wassell DT,Embery G

更新日期：1997-08-01 00:00:00

abstract：:A biodegradable microvessel scaffold comprised of distinct parenchymal and vascular compartments separated by a permeable membrane interface was conceptualized, fabricated, cellularized, and implanted. The device was designed with perfusable microfluidic channels on the order of 100 μm to mimic small blood vessels, an...

journal_title：Biomaterials

authors： Ye X,Lu L,Kolewe ME,Park H,Larson BL,Kim ES,Freed LE

更新日期：2013-12-01 00:00:00

abstract：:This study designs a pH-sensitive nanoparticle carrier of methotrexate (MTX) and combretastatin A4 (CA4) based on pullulan for the combination therapy against hepatocellular carcinoma (HCC). Briefly, N-urocanyl pullulan (URPA) with the degree of substitution (DS) of 5.2% was synthesized and then conjugated with MTX to...

journal_title：Biomaterials

authors： Wang Y,Chen H,Liu Y,Wu J,Zhou P,Wang Y,Li R,Yang X,Zhang N

更新日期：2013-09-01 00:00:00

abstract：:Two types of isoelastic endosseous dental implants were produced and their functionality was tested. One type consisted of a porous sintered TiTa30 alloy, the other had a special surface structure consisting of titanium wire loops. Their mechanical properties were optimized by the production parameter (sintering and d...

journal_title：Biomaterials

authors： Breme J,Biehl V,Schulte W,d'Hoedt B,Donath K

更新日期：1993-10-01 00:00:00

abstract：:Bacterial infection has been a threat to human health, and so early diagnosis and treatment of bacterial infection is an urgent problem that needs to be solved. In this work, a multifunctional theranostic selenium nanoplatform (Se@PEP-Ru NPs) with early imaging diagnosis and efficient treatment of bacterial infections...

journal_title：Biomaterials

authors： Huang N,Chen X,Zhu X,Xu M,Liu J

更新日期：2017-10-01 00:00:00

abstract：:The long-term behaviour of cellulose sponge implants, 10 x 10 x 5 mm in size, and tissue reactions in and around them were examined in the subcutaneous tissue of the rat from 1 to 60 weeks after implantation. The cellulose sponge used was filled up with connective tissue 4 to 8 weeks after implantation. Histologically...

journal_title：Biomaterials

authors： Märtson M,Viljanto J,Hurme T,Laippala P,Saukko P

更新日期：1999-11-01 00:00:00

abstract：:Polyethylene terephthalate (PET), ethylene-vinyl alcohol copolymer (EVOH) and Nylon 6 in plate form were treated with silane-coupling agents, a titanium alkoxide-alcohol solution and a hot HCl solution to form a thin crystalline titanium oxide layer. When placed in a simulated body fluid with ion concentrations nearly...

journal_title：Biomaterials

authors： Balas F,Kawashita M,Nakamura T,Kokubo T

更新日期：2006-03-01 00:00:00

abstract：:We genetically introduced the Fc-binding peptide (FcBP) into the loop of a self-assembled protein cage, ferritin, constituting four-fold symmetry at the surface to use it as a modular delivery nanoplatform. FcBP-presenting ferritin (FcBP-ferritin) formed very stable non-covalent complexes with both human and rabbit Ig...

journal_title：Biomaterials

authors： Kang HJ,Kang YJ,Lee YM,Shin HH,Chung SJ,Kang S

更新日期：2012-07-01 00:00:00

abstract：:Recent advances in 3D bioprinting have transformed the tissue engineering landscape by enabling the controlled placement of cells, biomaterials, and bioactive agents for the biofabrication of living tissues and organs. However, the application of 3D bioprinting is limited by the availability of cytocompatible and prin...

journal_title：Biomaterials

authors： Yu C,Miller KL,Schimelman J,Wang P,Zhu W,Ma X,Tang M,You S,Lakshmipathy D,He F,Chen S

更新日期：2020-11-01 00:00:00

abstract：:Synthetic small interfering RNA (siRNA) is a class of therapeutic entities that allow for specific silencing of target genes via RNA interference (RNAi) and comprise an enormous clinical potential for a variety of diseases, including cancer. However, efficient tissue-specific delivery of siRNA remains the major limita...

journal_title：Biomaterials

authors： Lee DJ,Kessel E,Edinger D,He D,Klein PM,Voith von Voithenberg L,Lamb DC,Lächelt U,Lehto T,Wagner E

更新日期：2016-01-01 00:00:00

abstract：:Electrical polarization and depolarization processes of the 45S5 type bioactive glass (BG) was studied by a thermally stimulated depolarization current (TSDC) and an complex impedance measurements. The depolarization processes were found to consist of three processes, which were observed as three peaks, P1, P2 and P3,...

journal_title：Biomaterials

authors： Obata A,Nakamura S,Yamashita K

更新日期：2004-09-01 00:00:00

abstract：:Achieving and maintaining safe and reliable lineage specific differentiation of stem cells is important for clinical translation of tissue engineering strategies. In an effort to circumvent the multitude of problems arising from the usage of growth factors and growth factor delivery systems, we have explored the use o...

journal_title：Biomaterials

authors： Huang CC,Narayanan R,Alapati S,Ravindran S

更新日期：2016-12-01 00:00:00

abstract：:In this work, therapeutic magnetic micro carriers (TMMC) guided in real time by a magnetic resonance imaging (MRI) system are proposed as a mean to improve drug delivery to tumor sites. MRI steering constraints and physiological parameters for the chemoembolization of liver tumors were taken into account to design mag...

journal_title：Biomaterials

authors： Pouponneau P,Leroux JC,Martel S

更新日期：2009-10-01 00:00:00