Formation of bone-like apatite on organic polymers treated with a silane-coupling agent and a titania solution.

abstract：:Dacron velour is often used to anchor a percutaneous device, like the catheter used in peritoneal dialysis. However, exit-site infections complicate this method of dialysis and are supposed to be related to the design of the catheter. In animal experiments, a percutaneous device provided with a titanium fibre mesh to ...

journal_title：Biomaterials

authors： Paquay YC,de Ruijter JE,van der Waerden JP,Jansen JA

更新日期：1996-06-01 00:00:00

abstract：:In this work, the in vitro interaction of cerebellar granule neurons prepared from 7-day-old Wistar rats and poly ethylene-co-vinyl alcohol (EVAL) membranes was investigated. Cells were cultured in smooth and particulate EVAL membranes for up to 7 days. Particulate membranes were prepared by using 1-octanol to precipi...

journal_title：Biomaterials

authors： Young TH,Lin CW,Cheng LP,Hsieh CC

更新日期：2001-07-01 00:00:00

abstract：:Platelet-derived growth factor BB (PDGF-BB) was an important inductive factor during wound healing, but the lack of efficient delivery system limited its clinical application. Here, a peptide of seven amino acids was firstly utilized to engineer PDGF-BB to construct a collagen-targeting system. This peptide functioned...

journal_title：Biomaterials

authors： Lin H,Chen B,Sun W,Zhao W,Zhao Y,Dai J

更新日期：2006-11-01 00:00:00

abstract：:A glucose biosensor was fabricated with loading of glucose oxidase (GOx) into a new organic-inorganic hybrid nanocomposite. The preparation involves formation of silica network into a Nafion (perfluorosulfonate ionomer) and subsequent loading of polyaniline grafted multiwalled carbon nanotubes (MWNT-g-PANI) onto Nafio...

journal_title：Biomaterials

authors： Gopalan AI,Lee KP,Ragupathy D,Lee SH,Lee JW

更新日期：2009-10-01 00:00:00

abstract：:Hydrogels are frequently employed as medical device biomaterials due to their advantageous biological properties, e.g. resistance to infection and encrustation, biocompatibility; however, their poor mechanical properties generally limit the scope of application to coatings of medical devices. To address this limitatio...

journal_title：Biomaterials

authors： Jones DS,McLaughlin DW,McCoy CP,Gorman SP

更新日期：2005-05-01 00:00:00

abstract：:Cutaneous melanoma is an increasingly common and potentially lethal malignancy of melanocytes, the melanin producing cells normally located in the basal layer of the skin epidermis. Despite major advances in cancer chemotherapeutics and immunotherapy, the success in treating metastatic melanoma remains poor. The notio...

journal_title：Biomaterials

authors： Chandrasekaran S,DeLouise LA

更新日期：2011-12-01 00:00:00

abstract：:We have developed a family of synthetic biodegradable polymers that are composed of structural units endogenous to the human metabolism, designated poly(polyol sebacate) (PPS) polymers. Material properties of PPS polymers can be tuned by altering the polyol monomer and reacting stiochiometric ratio of sebacic acid. Th...

journal_title：Biomaterials

authors： Bruggeman JP,de Bruin BJ,Bettinger CJ,Langer R

更新日期：2008-12-01 00:00:00

abstract：:Cell attachment, proliferation and differentiation on different materials depend largely on the surface properties of the materials. This study sheds light on the mechanism by which the modulation of the chemical composition of calcium silicate cements with different Si/Ca molar ratios could produce different cell res...

journal_title：Biomaterials

authors： Shie MY,Ding SJ

更新日期：2013-09-01 00:00:00

abstract：:The clinical usefulness of brain machine interfaces that employ penetrating silicon microelectrode arrays is limited by inconsistent performance at chronic time points. While it is widely believed that elements of the foreign body response (FBR) contribute to inconsistent single unit recording performance, the relatio...

journal_title：Biomaterials

authors： Nolta NF,Christensen MB,Crane PD,Skousen JL,Tresco PA

更新日期：2015-01-01 00:00:00

abstract：:Silica nanoparticles (SiO2-NPs) has been extensively exploited in biomedical fields and mostly designed to enter the circulatory system, however, few studies focused on the potential adverse effects of SiO2-NPs exposure on the blood-brain barrier (BBB) that serves as a critical barrier between the central nervous syst...

journal_title：Biomaterials

authors： Liu X,Sui B,Sun J

更新日期：2017-03-01 00:00:00

abstract：:Targeting delivery system has been widely used in packaging drugs for medical therapies attributed to its high efficiency and efficacy. A Traditional Chinese Medicine (TCM) formula consisting of Herba Epimedii has previously been shown to effectively treat postmenopausal osteoporosis. We have subsequently found that i...

journal_title：Biomaterials

authors： Huang L,Wang X,Cao H,Li L,Chow DH,Tian L,Wu H,Zhang J,Wang N,Zheng L,Yao X,Yang Z,Qin L

更新日期：2018-11-01 00:00:00

abstract：:Poly(epsilon-caprolactone) (PCL) was dissolved in four solvent systems, chloroform, tetrahydrofuran, acetone and ethyl acetate, and cast onto glass Petri dishes. The surface properties of the resulting films were investigated. The extent to which their properties were determined by the solvent used in each case was qu...

journal_title：Biomaterials

authors： Tang ZG,Black RA,Curran JM,Hunt JA,Rhodes NP,Williams DF

更新日期：2004-08-01 00:00:00

abstract：:We design a class of imprinted hybrid microgels that can optically monitor glucose levels with high sensitivity and selectivity in complex media at physiological pH, acting like a "glucose-indicator". Such imprinted hybrid microgels were made of Ag nanoparticles (NPs) in situ immobilized in molecularly imprinted gluco...

journal_title：Biomaterials

authors： Wu W,Shen J,Li Y,Zhu H,Banerjee P,Zhou S

更新日期：2012-10-01 00:00:00

abstract：:Combined treatment using nonviral agent-mediated enzyme/prodrug therapy and immunotherapy had been proposed as a powerful alternative method of cancer therapy. The present study was aimed to evaluate the cytotoxicity in vitro and the therapeutic efficacy in vivo when the cytosine deaminase/5-fluorocytosine (CD/5-FC) a...

journal_title：Biomaterials

authors： Liang B,He ML,Chan CY,Chen YC,Li XP,Li Y,Zheng D,Lin MC,Kung HF,Shuai XT,Peng Y

更新日期：2009-08-01 00:00:00

abstract：:Ultrasound imaging is a widely used imaging technique. The use of contrast agents has become an indispensible part of clinical ultrasound imaging, and molecular imaging via ultrasound has recently attracted significant attention. We recently reported that "Bubble liposomes" (BLs) encapsulating US imaging gas liposomes...

journal_title：Biomaterials

authors： Negishi Y,Hamano N,Tsunoda Y,Oda Y,Choijamts B,Endo-Takahashi Y,Omata D,Suzuki R,Maruyama K,Nomizu M,Emoto M,Aramaki Y

更新日期：2013-01-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) hold great promise as a cell source for regenerative medicine yet its culture, maintenance of pluripotency and induction of differentiation remain challenging. Conversely, graphene (G) and graphene oxide (GO) have captured tremendous interests in the fields of materials science, ...

journal_title：Biomaterials

authors： Chen GY,Pang DW,Hwang SM,Tuan HY,Hu YC

更新日期：2012-01-01 00:00:00

abstract：:Percutaneous implants are commonly associated with several problems, and different failure modes have been described. Infections constitute one serious complication which may lead to the removal of the implant. In contrast to infections around polymer implants, infections around skin-penetrating titanium implants anch...

journal_title：Biomaterials

authors： Holgers KM,Ljungh A

更新日期：1999-07-01 00:00:00

abstract：:The design of synthetic polymers may affect structural features of inflammatory cells, for example the expression of endogenous sugar receptor molecules like lectins in macrophages and foreign body giant multinucleate cells. This characteristic was studied histochemically by use of biotinylated (neo)glycoproteins. The...

journal_title：Biomaterials

authors： Smetana K Jr,Gabius HJ,Vacík J,Jelínková M,Lukás J

更新日期：1995-10-01 00:00:00

abstract：:The thermally responsive cholesteryl end-capped poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) and cholesteryl grafted poly[N-isopropylacrylamide-co-N-(hydroxymethyl) acrylamide] amphiphilic polymers were synthesized and utilized to encapsulate cyclosporin A (CyA) and indomethacin (IND) within core-shell nanopa...

journal_title：Biomaterials

authors： Chaw CS,Chooi KW,Liu XM,Tan CW,Wang L,Yang YY

更新日期：2004-08-01 00:00:00

abstract：:We have shown that nanoparticles (NPs) conjugated to trans-activating transcriptor (TAT) peptide bypass the efflux action of P-glycoprotein and increase the transport of the encapsulated ritonavir, a protease inhibitor (PI), across the blood-brain-barrier (BBB) to the central nervous system (CNS). A steady increase in...

journal_title：Biomaterials

authors： Rao KS,Reddy MK,Horning JL,Labhasetwar V

更新日期：2008-11-01 00:00:00

abstract：:This article is a review of recent developments of polymer-related stents mainly employed in the coronary arteries, including polymer-coated stents, biostable stents and biodegradable stents. Polymer paving is covered as well. The problems with the stents currently investigated and the development of new stents are di...

journal_title：Biomaterials

authors： Peng T,Gibula P,Yao KD,Goosen MF

更新日期：1996-04-01 00:00:00

abstract：:Site specific targeting remains elusive for gene and stem cell therapies in the cardiovascular field. One promising option involves use of devices that deliver larger and more sustained cell/gene payloads to specific disease sites using the versatility of percutaneous vascular access technology. Smooth muscle cells (S...

journal_title：Biomaterials

authors： Kumar AH,Martin K,Doyle B,Huang CL,Pillai GK,Ali MT,Skelding KA,Wang S,Gleeson BM,Jahangeer S,Ritman EL,Russell SJ,Caplice NM

更新日期：2014-10-01 00:00:00

abstract：:A major cross-cutting problem for glioma therapy is the poor extravasation and penetration of the payload drug in target glioma parenchyma. Here, to overcome these obstacles, a tumor vessel recognizing and tumor penetrating system is developed by functionalizating the poly (ethyleneglycol)-poly (L-lactic-co-glycolic a...

journal_title：Biomaterials

authors： Kang T,Gao X,Hu Q,Jiang D,Feng X,Zhang X,Song Q,Yao L,Huang M,Jiang X,Pang Z,Chen H,Chen J

更新日期：2014-05-01 00:00:00

abstract：:Nanodiamond application in biotechnological and medical fields is nowadays in continuous progress. In fact, biocompatibility, reduced dimensions and high surface chemical interaction are specific features that make nanodiamonds perfect intracellular carriers of bioactive compounds. By confocal microscopy, we confirmed...

journal_title：Biomaterials

authors： Gismondi A,Reina G,Orlanducci S,Mizzoni F,Gay S,Terranova ML,Canini A

更新日期：2015-01-01 00:00:00

abstract：:To investigate the role that the micro/nano-environment plays on the differentiation pathway of bone marrow stromal cells (BMSCs) into osteoblasts, we employed a 2D substrate coated with turnip yellow mosaic virus (TYMV) particles. TYMV is a non-enveloped icosahedral plant virus which has an average diameter 28 nm and...

journal_title：Biomaterials

authors： Kaur G,Valarmathi MT,Potts JD,Wang Q

更新日期：2008-10-01 00:00:00

abstract：:In order to evaluate degradation kinetics and biocompatibility of a resorbable poly(D,L-lactic acid) (PDLLA) plug for total cemented hip prostheses, an experimental in vitro and in vivo study was carried out. Degradation rate studies were performed in Ringer solution and after in vivo plug implantation in the femoral ...

journal_title：Biomaterials

authors： Giardino R,Fini M,Aldini NN,Giavaresi G,Rocca M,Orienti L,de Lollis A,Fambri L

更新日期：1997-07-01 00:00:00

abstract：:Small-diameter vascular grafts made of biomedical polytetrafluoroethylene (PTFE) suffer from the poor long-term patency rate originating from thrombosis and intimal hyperplasia, which can be ascribed to the insufficient endothelialization and chronic inflammation of the materials. Hence, bio-functionalization of PTFE ...

journal_title：Biomaterials

authors： Gao A,Hang R,Li W,Zhang W,Li P,Wang G,Bai L,Yu XF,Wang H,Tong L,Chu PK

更新日期：2017-09-01 00:00:00

abstract：:A silicone-based prepolymer was used as the major component for the fabrication of novel ocular devices. Gentamicin sulphate was used as a probe drug, due to its high aqueous solubility and widespread application. Mechanical properties of films containing the drug before and after gamma sterilization and exposure to h...

journal_title：Biomaterials

authors： Bawa R,Nandu M

更新日期：1990-11-01 00:00:00

abstract：:Chondrocytes isolated from human foetal epiphyseal cartilage were seeded dynamically into polyglycolic acid (PGA) scaffolds and cultured in recirculation column bioreactors to produce tissue-engineered cartilage. Several culture techniques with the potential to provide endogenous growth factors and other conditions be...

journal_title：Biomaterials

authors： Mahmoudifar N,Doran PM

更新日期：2005-12-01 00:00:00

abstract：:Tissue engineering and regenerative medicine technologies offer promising therapies for both medicine and dentistry. Our long-term goal is to create functional biomimetic tooth buds for eventual tooth replacement in humans. Here, our objective was to create a biomimetic 3D tooth bud model consisting of dental epitheli...

journal_title：Biomaterials

authors： Monteiro N,Smith EE,Angstadt S,Zhang W,Khademhosseini A,Yelick PC

更新日期：2016-11-01 00:00:00