Role of polymers in improving the results of stenting in coronary arteries.

abstract：:The development of biohybrid organs (BHO) will benefit from improved membranes regarding transport and cell contacting properties. Here we describe in a first study the development and testing of membranes made of polyacrylonitrile (PAN) and polysulfone (PSU) for the immobilisation of kidney epithelial cells. Comparat...

journal_title：Biomaterials

authors： Fey-Lamprecht F,Groth T,Albrecht W,Paul D,Gross U

更新日期：2000-01-01 00:00:00

abstract：:Breast cancer cells (BCC) and macrophages are known to interact via epidermal growth factor (EGF) produced by macrophages and colony stimulating factor-1 (CSF-1) produced by BCC. Despite contradictory findings, this interaction is perceived as a paracrine loop. Further, the underlying mechanism of interaction remains ...

journal_title：Biomaterials

authors： Onal S,Turker-Burhan M,Bati-Ayaz G,Yanik H,Pesen-Okvur D

更新日期：2021-01-01 00:00:00

abstract：:Brain tissue inflammatory responses, including neuronal loss and gliosis at the neural electrode/tissue interface, limit the recording stability and longevity of neural probes. The neural adhesion molecule L1 specifically promotes neurite outgrowth and neuronal survival. In this study, we covalently immobilized L1 on ...

journal_title：Biomaterials

authors： Azemi E,Lagenaur CF,Cui XT

更新日期：2011-01-01 00:00:00

abstract：:Although a variety of nanoparticles (NPs) functionalized with amphotericin B, an antifungal agent widely used in the clinic, have been studied in the last years their cytotoxicity profile remains elusive. Here we show that human endothelial cells take up high amounts of silica nanoparticles (SNPs) conjugated with amph...

journal_title：Biomaterials

authors： Paulo CS,Lino MM,Matos AA,Ferreira LS

更新日期：2013-07-01 00:00:00

abstract：:Human stem cells are vulnerable to unfavorable conditions, and their transportation relies on costly and inconvenient cryopreservation. We report here that human mesenchymal stem cells (MSC) in spheroids survived ambient conditions (AC) many days longer than in monolayer. Under AC, the viability of MSC in spheroids re...

journal_title：Biomaterials

authors： Jiang B,Yan L,Miao Z,Li E,Wong KH,Xu RH

更新日期：2017-07-01 00:00:00

abstract：:Titanium (Ti) osseointegration is critical for the success of dental and orthopedic implants. Previous studies have shown that surface roughness at the micro- and submicro-scales promotes osseointegration by enhancing osteoblast differentiation and local factor production. Only relatively recently have the effects of ...

journal_title：Biomaterials

authors： Gittens RA,McLachlan T,Olivares-Navarrete R,Cai Y,Berner S,Tannenbaum R,Schwartz Z,Sandhage KH,Boyan BD

更新日期：2011-05-01 00:00:00

abstract：:A poly(urethane urea) (PUU) synthesized from 2,4-toluene diisocyanate (TDI) and polyethylene glycol (PEG) with ethylenediamine (ED) as the chain extender was rendered radiopaque by attaching 3,4,5-triiodobenzoic acid (TIB) onto the polymer backbone. The radiopaque polyurethane obtained was characterized by infra red (...

journal_title：Biomaterials

authors： James NR,Jayakrishnan A

更新日期：2007-07-01 00:00:00

abstract：:Periprosthetic tissues observed at sites of loose total joint implants exhibit abundant macrophages, lymphocytes, fibroblasts and particulate debris. Macrophages phagocytose orthopaedic debris and release proinflammatory cytokines, chemokines, matrix metalloproteinases and other substances. In addition, other cell typ...

journal_title：Biomaterials

authors： Trindade MC,Lind M,Sun D,Schurman DJ,Goodman SB,Smith RL

更新日期：2001-02-01 00:00:00

abstract：:The development of electrospun ultrafine fibres from biodegradable and biocompatible polymers has created exciting opportunities for biomedical applications. Fibre meshes with high surface area, suitable porosity and stiffness have been produced. Despite desirable structural and topographical properties, for most synt...

journal_title：Biomaterials

authors： Duque Sánchez L,Brack N,Postma A,Pigram PJ,Meagher L

更新日期：2016-11-01 00:00:00

abstract：:Surface plasmon resonance (SPR) sensing has long been used to study biomolecular binding events and their kinetics in a label-free way. This approach has recently been extended to SPR microscopy, which is an ideal tool for probing large microarrays of biomolecules for their binding interactions with various partners a...

journal_title：Biomaterials

authors： Campbell CT,Kim G

更新日期：2007-05-01 00:00:00

abstract：:A two-layer hydroxyapatite (HA)/HA+TiO(2) bond coat composite coating (HTH coating) on titanium was fabricated by plasma spraying. The HA+TiO(2) bond coat (HTBC) consists of 50 vol% HA and 50 vol% TiO(2) (HT). The microstructural characterization of the HTH coatings before and after heat treatment was conducted by usi...

journal_title：Biomaterials

authors： Lu YP,Li MS,Li ST,Wang ZG,Zhu RF

更新日期：2004-08-01 00:00:00

abstract：:High sensitivity at ultra-high field (UHF) and sufficient potential to penetrate the brain are the most desirable characteristics in the development of contrast agents (CAs) for magnetic resonance imaging (MRI). However, incorporating such qualities into a single nanocarrier is challenging. Herein, we report a new str...

journal_title：Biomaterials

authors： Kim HK,Baek AR,Choi G,Lee JJ,Yang JU,Jung H,Lee T,Kim D,Kim M,Cho A,Lee GH,Chang Y

更新日期：2020-06-01 00:00:00

abstract：:Bioactive glasses are potentially useful as bone defect fillers, and vascular endothelial growth factor (VEGF) has demonstrated benefit in bone regeneration as well. We hypothesized that the specific combination of prolonged localized VEGF presentation from a matrix coated with a bioactive glass may enhance bone regen...

journal_title：Biomaterials

authors： Leach JK,Kaigler D,Wang Z,Krebsbach PH,Mooney DJ

更新日期：2006-06-01 00:00:00

abstract：:Fracture toughness and hardness properties of CaO-P2O5 glass-reinforced hydroxyapatite composites have been assessed using indentation techniques and results calculated according to Laugier and Evans' equations. Both properties showed to be dependent upon several microstructural characteristics, namely residual porosi...

journal_title：Biomaterials

authors： Lopes MA,Monteiro FJ,Santos JD

更新日期：1999-11-01 00:00:00

abstract：:The aim of this study was to evaluate the bacterial adherence to biodegradable self-reinforced polyglycolic acid (SR-PGA) and self-reinforced poly-DL-lactic acid (SR-PLA 96) spiral stents in vitro. They are used as temporary urethral stents in urology. Gold-plated metal wire, polyurethane and latex were used as contro...

journal_title：Biomaterials

authors： Pétas A,Vuopio-Varkila J,Siitonen A,Välimaa T,Talja M,Taari K

更新日期：1998-04-01 00:00:00

abstract：:Poly(ether-ether-ketone) (PEEK) has been used as a load bearing orthopaedic implant material with clinical success. All of the orthopaedic applications contain stress concentrations (notches) in their design; however, little work has been done to examine the fatigue behavior of PEEK in the presence of a notch. This wo...

journal_title：Biomaterials

authors： Sobieraj MC,Murphy JE,Brinkman JG,Kurtz SM,Rimnac CM

更新日期：2010-12-01 00:00:00

abstract：:Biocompatibility and tissue regenerating capacity are essential characteristics in the design of collagenous biomaterials for tissue engineering. Attachment of glycosaminoglycans (GAGs) to collagen may add to these characteristics by creating an appropriate micro-environment. In this study, porous type I collagen matr...

journal_title：Biomaterials

authors： Pieper JS,van Wachem PB,van Luyn MJA,Brouwer LA,Hafmans T,Veerkamp JH,van Kuppevelt TH

更新日期：2000-08-01 00:00:00

abstract：:Implantation of a medical implant within the body inevitably triggers a host inflammatory response that negatively impacts its function and longevity. Nevertheless, the degree and severity of this response may be reduced by selecting appropriate materials, implant geometry, surface topography and surface treatment. He...

journal_title：Biomaterials

authors： Li J,Chu MK,Gordijo CR,Abbasi AZ,Chen K,Adissu HA,Löhn M,Giacca A,Plettenburg O,Wu XY

更新日期：2015-04-01 00:00:00

abstract：:A major role of respiratory mucus is to trap inhaled particles, including pathogens and environmental particulates, to limit body exposure. Despite the tremendous health implications, how particle size and surface chemistry affect mobility in respiratory mucus from humans without lung disease is not known. We prepared...

journal_title：Biomaterials

authors： Schuster BS,Suk JS,Woodworth GF,Hanes J

更新日期：2013-04-01 00:00:00

abstract：OBJECT:Allogenic human fascia lata used in neurosurgery, as dura mater substitute, can be associated with a risk of viral and bacterial transmission. Chemical and physical procedures, developed to inactivate virus and bacteria, have been applied to fascia lata. The aim of this study consists in the evaluation of the bi...

journal_title：Biomaterials

authors： Dufrane D,Cornu O,Delloye C,Schneider YJ

更新日期：2002-07-01 00:00:00

abstract：:Mesenchymal stromal cells (hMSCs) are advancing into the clinic but the therapeutic efficacy of hMSCs faces the problem of donor variability. In bone tissue engineering, no reliable markers have been identified which are able to predict the bone-forming capacity of hMSCs prior to implantation. To this end, we isolated...

journal_title：Biomaterials

authors： Mentink A,Hulsman M,Groen N,Licht R,Dechering KJ,van der Stok J,Alves HA,Dhert WJ,van Someren EP,Reinders MJ,van Blitterswijk CA,de Boer J

更新日期：2013-06-01 00:00:00

abstract：:A novel technique has been developed for microstructural studies of bone. The spatial organizations of the mineral and collagen fibres in bone have been a matter of discussion for some time, with numerous diverse observations arising from various preparative techniques. In this latest investigation details of the mine...

journal_title：Biomaterials

authors： Green M,Isaac DH,Jenkins GM

更新日期：1985-05-01 00:00:00

abstract：:The in vivo evaluation, in New Zealand rabbits, of a SiO(2)-P(2)O(5)-CaO sol-gel glass and a SiO(2)-P(2)O(5)-CaO-MgO glass-ceramic, both bioactive in Kokubo's simulated body fluid (SBF), is presented. Bone defects, performed in the lateral aspect of distal right femoral epiphysis, 5mm in diameter and 4mm in depth, wer...

journal_title：Biomaterials

authors： Gil-Albarova J,Garrido-Lahiguera R,Salinas AJ,Román J,Bueno-Lozano AL,Gil-Albarova R,Vallet-Regí M

更新日期：2004-08-01 00:00:00

abstract：:Single-stranded oligonucleotide-conjugated lipids (ssDNA-PEG-lipids) that associate with the cell membrane confer to the cell an artificial adhesive capability via sequence-specific hybridization to complementary oligonucleotides, forming bonds of double stranded oligonucleotides (dsDNA). Such artificial tethers permi...

journal_title：Biomaterials

authors： Hoffecker IT,Takemoto N,Arima Y,Iwata H

更新日期：2015-01-01 00:00:00

abstract：:Metronomic chemotherapy, which is defined as a low-dose and frequent administration of cytotoxic drugs without drug-free breaks, has been recently emerged as an alternative to traditional MTD therapy and has shown therapeutic benefit in breast cancer patients in numbers of clinical studies. Unlike MTD, metronomic chem...

journal_title：Biomaterials

authors： Chung SW,Kim GC,Kweon S,Lee H,Choi JU,Mahmud F,Chang HW,Kim JW,Son WC,Kim SY,Byun Y

更新日期：2018-11-01 00:00:00

abstract：:Combined treatment using nonviral agent-mediated enzyme/prodrug therapy and immunotherapy had been proposed as a powerful alternative method of cancer therapy. The present study was aimed to evaluate the cytotoxicity in vitro and the therapeutic efficacy in vivo when the cytosine deaminase/5-fluorocytosine (CD/5-FC) a...

journal_title：Biomaterials

authors： Liang B,He ML,Chan CY,Chen YC,Li XP,Li Y,Zheng D,Lin MC,Kung HF,Shuai XT,Peng Y

更新日期：2009-08-01 00:00:00

abstract：:Most urgent health problems are related to a blood vessel formation failure. The use of stem cells from different sources or species for both in vitro and in vivo engineering of endothelium does not necessarily imply their direct commitment towards a vascular phenotype. In the present study, we used human amniotic flu...

journal_title：Biomaterials

authors： Mirabella T,Cilli M,Carlone S,Cancedda R,Gentili C

更新日期：2011-05-01 00:00:00

abstract：:Hydrogels, microgels and nanogels have emerged as versatile and viable platforms for sustained protein release, targeted drug delivery, and tissue engineering due to excellent biocompatibility, a microporous structure with tunable porosity and pore size, and dimensions spanning from human organs, cells to viruses. In ...

journal_title：Biomaterials

authors： Jiang Y,Chen J,Deng C,Suuronen EJ,Zhong Z

更新日期：2014-06-01 00:00:00

abstract：:Heparin-conjugated electrospun poly(ε-caprolactone) (PCL)/gelatin scaffolds were developed to provide controlled release of platelet-derived growth factor-BB (PDGF-BB) and allow prolonged bioactivity of this molecule. A mixture of PCL and gelatin was electrospun into three different morphologies. Next, heparin molecul...

journal_title：Biomaterials

authors： Lee J,Yoo JJ,Atala A,Lee SJ

更新日期：2012-10-01 00:00:00

abstract：:The objective of this study was to investigate the effect of repeated applications of a neutral NaF solution on the surface roughness of four conventional glass ionomer cements (GIC) (ChemFil Superior encapsulated, Fuji Cap II, Ketac-Fil and Hi Dense), three resin-modified (RM-) GIC (Fuji II LC encapsulated, Photac-Fi...

journal_title：Biomaterials

authors： De Witte AM,De Maeyer EA,Verbeeck RM

更新日期：2003-05-01 00:00:00