A sequential 3D bioprinting and orthogonal bioconjugation approach for precision tissue engineering.

abstract：:Polydimethylsiloxanes exhibit hydrophobic behaviour and poor wettability. These features impose some problems with the clinical performance of the material when used for the construction of intraoral and extraoral facial prostheses. Surface active agents were added to modify the surface energy of the polydimethylsilox...

journal_title：Biomaterials

authors： Polyzois GL,Winter RW,Stafford GD

更新日期：1991-01-01 00:00:00

abstract：:Poor fixation of bone replacement implants, e.g. the artificial hip, in implantation sites with inferior bone quality and quantity may be overcome by the use of implants coated with a cultured living bone equivalent. In this study, we tested, respectively, amorphous carbonated apatite (CA)- and crystalline octacalcium...

journal_title：Biomaterials

authors： Dekker RJ,de Bruijn JD,Stigter M,Barrere F,Layrolle P,van Blitterswijk CA

更新日期：2005-09-01 00:00:00

abstract：:To broaden the clinical application of cartilage regenerative medicine, we should develop an implant-type tissue-engineered cartilage with firmness and 3-D structure. For that, we attempted to use a porous biodegradable polymer scaffold in the combination with atelocollagen hydrogel, and optimized the structure and co...

journal_title：Biomaterials

authors： Tanaka Y,Yamaoka H,Nishizawa S,Nagata S,Ogasawara T,Asawa Y,Fujihara Y,Takato T,Hoshi K

更新日期：2010-06-01 00:00:00

abstract：:Chemotherapeutic agents often cause severe side effects because they produce a similar cytotoxicity in both cancerous and healthy cells. In this study, a rational strategy was implemented to take advantage of a combination of both tumor microenvironment-sensitive polypeptides (TMSP) and folate to create a more selecti...

journal_title：Biomaterials

authors： Gao W,Xiang B,Meng TT,Liu F,Qi XR

更新日期：2013-05-01 00:00:00

abstract：:Animal models have been used extensively to investigate the biology of fracture healing and spinal fusion. The goal of each spinal fusion model is to try and reproduce the correct sequence of events during osseous healing in humans. Animal models allow us the capability of dialing in fusion rates and fusion parameters...

journal_title：Biomaterials

authors： Khan SN,Lane JM

更新日期：2004-04-01 00:00:00

abstract：:Recent advances in biomaterial surface engineering have shown that surface biomechanical, spatial and topographical properties can elicit control over fundamental biological processes such as cell shape, proliferation, differentiation and apoptosis. Along these lines, we have very recently shown that the self-assembly...

journal_title：Biomaterials

authors： George PA,Quinn K,Cooper-White JJ

更新日期：2010-02-01 00:00:00

abstract：:Chitosan (CHT)/poly(ɛ-caprolactone) (PCL) blend 3D fiber-mesh scaffolds were studied as possible support structures for articular cartilage tissue (ACT) repair. Micro-fibers were obtained by wet-spinning of three different polymeric solutions: 100:0 (100CHT), 75:25 (75CHT) and 50:50 (50CHT) wt.% CHT/PCL, using a commo...

journal_title：Biomaterials

authors： Neves SC,Moreira Teixeira LS,Moroni L,Reis RL,Van Blitterswijk CA,Alves NM,Karperien M,Mano JF

更新日期：2011-02-01 00:00:00

abstract：:Decellularized native extracellular matrix (ECM) biomaterials are widely used in tissue engineering and have reached clinical application as biomesh implants. To enhance their regenerative properties and postimplantation performance, ECM biomaterials could be functionalized via immobilization of bioactive molecules. T...

journal_title：Biomaterials

authors： Ren X,Evangelista-Leite D,Wu T,Rajab TK,Moser PT,Kitano K,Economopoulos KP,Gorman DE,Bloom JP,Tan JJ,Gilpin SE,Zhou H,Mathisen DJ,Ott HC

更新日期：2018-11-01 00:00:00

abstract：:Understanding how engineered tissue scaffold architecture affects cell morphology, metabolism, phenotypic expression, as well as predicting material mechanical behavior has recently received increased attention. In the present study, an image-based analysis approach that provides an automated tool to characterize engi...

journal_title：Biomaterials

authors： D'Amore A,Stella JA,Wagner WR,Sacks MS

更新日期：2010-07-01 00:00:00

abstract：:Polydispersed poly(L-lactic acid) (PLLA) membranes comprised of blends of monodispersed PLLA of weight average molecular weight of 82,500 and 7600 were fabricated to investigate the effect of polydispersity on degradation characteristics. The PLLA blends exhibited large spherulites of high molecular weight chains embe...

journal_title：Biomaterials

authors： von Recum HA,Cleek RL,Eskin SG,Mikos AG

更新日期：1995-04-01 00:00:00

abstract：:Driven by the clinical need for a strong tissue adhesive with elastomeric material properties, a departure from legacy crosslinking chemistries was sought as a multipurpose platform for tissue mending. A fresh approach to bonding wet substrates has yielded a synthetic biomaterial that overcomes the drawbacks of free-r...

journal_title：Biomaterials

authors： Djordjevic I,Pokholenko O,Shah AH,Wicaksono G,Blancafort L,Hanna JV,Page SJ,Nanda HS,Ong CB,Chung SR,Chin AYH,McGrouther D,Choudhury MM,Li F,Teo JS,Lee LS,Steele TWJ

更新日期：2020-11-01 00:00:00

abstract：:Hydrogels produced from self-assembling peptides and peptide derivatives are being investigated as synthetic extracellular matrices for defined cell culture substrates and scaffolds for regenerative medicine. In many cases, however, they are less stiff than the tissues and extracellular matrices they are intended to m...

journal_title：Biomaterials

authors： Jung JP,Jones JL,Cronier SA,Collier JH

更新日期：2008-05-01 00:00:00

abstract：:It is estimated that 4 to 5 million people are currently co-infected with Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV). HIV/HCV co-infection is associated with unique health risks including increased hepatotoxicity of antiretrovirals, accelerated progression of HCV and liver diseases. The standard in...

journal_title：Biomaterials

authors： Zhang J,Mulvenon A,Makarov E,Wagoner J,Knibbe J,Kim JO,Osna N,Bronich TK,Poluektova LY

更新日期：2013-05-01 00:00:00

abstract：:A novel low-pressure radio-frequency plasma treatment protocol was developed to achieve the effective through-thickness surface modification of large porous poly (D,L-lactide) (PDLLA) polymer scaffolds using air or water: ammonia plasma treatments. Polymer films were modified as controls. Scanning electron micrographs...

journal_title：Biomaterials

authors： Safinia L,Datan N,Höhse M,Mantalaris A,Bismarck A

更新日期：2005-12-01 00:00:00

abstract：:Space experimentation of cardiomyocyte differentiation from human induced pluripotent stem cells offers an exciting opportunity to explore the potential of these cells for disease modeling, drug discovery and regenerative medicine. Previous studies on the International Space Station were done with 2D non-cryopreserved...

journal_title：Biomaterials

authors： Rampoldi A,Jha R,Fite J,Boland G,Xu C

更新日期：2021-01-11 00:00:00

abstract：:Membranes based on mechanically supported poly(vinyl alcohol) (PVA) hydrogels with mesh-size asymmetry were developed for potential application in biohybrid artificial organs. The pores of cellulose ester microfiltration membranes were impregnated with a PVA solution, which was lightly crosslinked with glutaraldehyde ...

journal_title：Biomaterials

authors： Dai WS,Barbari TA

更新日期：2000-07-01 00:00:00

abstract：:Poly(ε-caprolactone)-b-Poly(N-vinylpyrrolidone) (PCL-b-PVP) copolymers with different PVP block length were synthesized by xanthate-mediated reverse addition fragment transfer polymerization (RAFT) and the xanthate chain transfer agent on chain end was readily translated to hydroxy or aldehyde for conjugating various ...

journal_title：Biomaterials

authors： Zhu Z,Xie C,Liu Q,Zhen X,Zheng X,Wu W,Li R,Ding Y,Jiang X,Liu B

更新日期：2011-12-01 00:00:00

abstract：:A-B-type block copolymers, consisting of polystyrene (PST) or poly(methyl methacrylate) (PMMA) forming segment (A) and poly(gamma-benzyl L-glutamate) (P[Glu(OBzl)]) segment (B), were synthesized and the thrombus formation on these block copolymer films was investigated in relation to the adsorption of plasma proteins ...

journal_title：Biomaterials

authors： Mori A,Ito Y,Sisido M,Imanishi Y

更新日期：1986-09-01 00:00:00

abstract：:ROCK activity increases due to ECM rigidity in the tumor microenvironment and promotes a malignant phenotype via actomyosin contractility. Invasive migration is facilitated by actin-rich adhesive protrusions known as invadopodia that degrade the ECM. Invadopodia activity is dependent on matrix rigidity and contractile...

journal_title：Biomaterials

authors： Jerrell RJ,Parekh A

更新日期：2016-04-01 00:00:00

abstract：:Characterization of complex adsorbed protein films is a critical aspect of biomaterials science, particularly in understanding the in vivo response to biomaterials. The surface analysis techniques electron spectroscopy for chemical analysis (ESCA) and time-of-flight secondary ion mass spectrometry (ToF-SIMS) are parti...

journal_title：Biomaterials

authors： Wagner MS,Horbett TA,Castner DG

更新日期：2003-05-01 00:00:00

abstract：:A variety of bioactive composites have been investigated over the last two decades as substitute materials for diseased or damaged tissues in the human body. In this paper, the rationale and strategy of developing these composites are given. Major factors influencing the production and performance of bioactive composi...

journal_title：Biomaterials

authors： Wang M

更新日期：2003-06-01 00:00:00

abstract：:The influence of processing-introduced flaws and heat treatment on the strength degradation of the dental core material has recently been observed. However, there are insufficient studies which investigate the role of grinding, grinding orientation, sandblasting, polishing and heat treatment on the strength of In-Cera...

journal_title：Biomaterials

authors： Guazzato M,Albakry M,Quach L,Swain MV

更新日期：2004-05-01 00:00:00

abstract：:Pancreatic cancer has the worst prognosis of all cancers due to disease aggressiveness and paucity of early detection platforms. We developed biomaterial scaffolds that recruit metastatic tumor cells and reflect the immune dysregulation of native metastatic sites. While this platform has shown promise in orthotopic br...

journal_title：Biomaterials

authors： Bushnell GG,Orbach SM,Ma JA,Crawford HC,Wicha MS,Jeruss JS,Shea LD

更新日期：2020-12-23 00:00:00

abstract：:Implantable monolithic and reservoir-like water-swellable drainage devices were developed for the subconjunctival sustained release of 5-fluorouracil (5-FU) in glaucoma-filtering surgery. A water-swellable matrix was formed of a copolymer of 2-hydroxyethyl methacrylate (HEMA) with different amounts of ethylene glycol ...

journal_title：Biomaterials

authors： Gökce M,Akata RF,Kiremitçi-Gümüşderelioğlu M

更新日期：1996-05-01 00:00:00

abstract：:Porous scaffolds for skin tissue engineering were fabricated by freeze-drying the mixture of collagen and chitosan solutions. Glutaraldehyde (GA) was used to treat the scaffolds to improve their biostability. Confocal laser scanning microscopy observation confirmed the even distribution of these two constituent materi...

journal_title：Biomaterials

authors： Ma L,Gao C,Mao Z,Zhou J,Shen J,Hu X,Han C

更新日期：2003-11-01 00:00:00

abstract：:To avoid the overheating effect of excitation light and improve the efficacy of photodynamic therapy (PDT) of upconversion nanoplatform, a novel nanoprobe based on 808 nm-excited upconversion nanocomposites (T-UCNPs@Ce6@mSiO2) with low heating effect and deep penetration has been successfully constructed for targeted ...

journal_title：Biomaterials

authors： Zeng L,Pan Y,Zou R,Zhang J,Tian Y,Teng Z,Wang S,Ren W,Xiao X,Zhang J,Zhang L,Li A,Lu G,Wu A

更新日期：2016-10-01 00:00:00

abstract：:Arterial catheterization is one of the most frequently performed inpatient diagnostic and therapeutic procedures in the development countries. Complications may occur after any catheterization from inadequate hemostasis, particularly in the setting of aggressive anticoagulation. This study suggests that microcrystalli...

journal_title：Biomaterials

authors： Hoekstra A,Struszczyk H,Kivekäs O

更新日期：1998-08-01 00:00:00

abstract：:The purpose of this study is to analyze the roles of two non-invasive techniques, bone scintigraphy and resonance frequency analysis (RFA), in the osseointegration assessment. Sixty implants with sandblasted/acid-etched (SA) or machined (MA) surface were placed into the distal femur condyles of 30 rabbits. At 1, 2, 4,...

journal_title：Biomaterials

authors： Zhou Y,Jiang T,Qian M,Zhang X,Wang J,Shi B,Xia H,Cheng X,Wang Y

更新日期：2008-02-01 00:00:00

abstract：:The purpose of this article is to examine the effects of tricaprin on the physical characteristics and in vitro release of etoposide from poly (lactic-co-glycolic acid) microspheres. The microspheres were synthesized through the use of a single-emulsion solvent-extraction procedure. Samples from each batch of microsph...

journal_title：Biomaterials

authors： Schaefer MJ,Singh J

更新日期：2002-08-01 00:00:00

abstract：:Retinal pigment epithelial (RPE) cellular morphology and function are vital to the health of the retina. In age-related macular degeneration, RPE dysfunction and changes in Bruch's membrane occur. Thus, a potential cure is a dual-layer biomimetic transplant consisting of a layer of healthy RPE cells cultured on a supp...

journal_title：Biomaterials

authors： Lee CJ,Fishman HA,Bent SF

更新日期：2007-04-01 00:00:00