Effect of a CCR1 receptor antagonist on systemic trafficking of MSCs and polyethylene particle-associated bone loss.

abstract：:Patients regularly taking non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin (IND) have a risk of small intestinal injuries. In this study, we have developed an oral nanotherapeutics by using a redox nanoparticle (RNP(O)), which is prepared by self-assembly of an amphiphilic block copolymer that posse...

journal_title：Biomaterials

authors： Sha S,Vong LB,Chonpathompikunlert P,Yoshitomi T,Matsui H,Nagasaki Y

更新日期：2013-11-01 00:00:00

abstract：:Reactive diluents such as triethyleneglycol-dimethacrylate (TEGDMA) have been widely used with bisphenol-A-glycidyl-dimethacrylate (Bis-GMA) to achieve restorative resins with appropriate viscosity and higher conversion. However, additional water sorption and polymerization shrinkage were also introduced. The aim of t...

journal_title：Biomaterials

authors： Lu H,Stansbury JW,Nie J,Berchtold KA,Bowman CN

更新日期：2005-04-01 00:00:00

abstract：:Periosteal derived bovine osteoblast-like cells migrated in culture onto an ionomeric cement. Cell cultures were maintained for 4 weeks and used to study the in vitro behaviour of cells on the ionomeric bone cement (IC). The cells produced bone matrix proteins (osteocalcin, bone sialoprotein II) and were osteoblast-li...

journal_title：Biomaterials

authors： Meyer U,Szulczewski DH,Barckhaus RH,Atkinson M,Jones DB

更新日期：1993-10-01 00:00:00

abstract：:Targeting delivery system has been widely used in packaging drugs for medical therapies attributed to its high efficiency and efficacy. A Traditional Chinese Medicine (TCM) formula consisting of Herba Epimedii has previously been shown to effectively treat postmenopausal osteoporosis. We have subsequently found that i...

journal_title：Biomaterials

authors： Huang L,Wang X,Cao H,Li L,Chow DH,Tian L,Wu H,Zhang J,Wang N,Zheng L,Yao X,Yang Z,Qin L

更新日期：2018-11-01 00:00:00

abstract：:Well-characterised human osteoblastic bone marrow cell cultures are a useful in vitro tool to analyse bone tissue/biomaterials interactions. In this work, human bone marrow was cultured in experimental conditions described to favour osteoblastic differentiation and, serially passaged cells were cultured in two widely ...

journal_title：Biomaterials

authors： Coelho MJ,Cabral AT,Fernande MH

更新日期：2000-06-01 00:00:00

abstract：:Here, we demonstrated dimethyldioctadecylammonium bromide (DODAB), a cationic lipid, bilayer coated Au nanoparticles (AuNPs) could efficiently deliver two types of plasmid DNA into human embryonic kidney cells (HEK 293) in the presence of serum. The transfection efficiency of AuNPs was about five times higher than tha...

journal_title：Biomaterials

authors： Li P,Li D,Zhang L,Li G,Wang E

更新日期：2008-09-01 00:00:00

abstract：:The ability to manipulate and control the surface properties, without altering the substrate properties, is of crucial importance in the designing of biomedical materials. In this work, surface-initiated atom transfer radical polymerization (ATRP) is employed to tailor the functionality of polycaprolactone (PCL) film ...

journal_title：Biomaterials

authors： Xu FJ,Wang ZH,Yang WT

更新日期：2010-04-01 00:00:00

abstract：:3D printing is known as a cost-effective technique that shows huge potential in fabrication of graft substitutes for bone tissue regeneration. However, the tradeoff between 3D printability, mechanical strength and bioactivity of the printed materials (i.e., inks) remains a challenge. In this work, we present a novel p...

journal_title：Biomaterials

authors： Yang Y,Zhang Q,Xu T,Zhang H,Zhang M,Lu L,Hao Y,Fuh JH,Zhao X

更新日期：2020-12-01 00:00:00

abstract：:Previously we demonstrated the ability of ethyl glycinato substituted polyphosphazenes to neutralize the acidic degradation products and control the degradation rate of poly(lactic acid-glycolic acid) (PLAGA) by blending. In this study, blends of high strength poly[(50% ethyl alanato) (50% p-phenyl phenoxy) phosphazen...

journal_title：Biomaterials

authors： Deng M,Nair LS,Nukavarapu SP,Kumbar SG,Jiang T,Krogman NR,Singh A,Allcock HR,Laurencin CT

更新日期：2008-01-01 00:00:00

abstract：:Sodium alginate hydrogel, stabilized with gelatin, is a suitable, biologically inert matrix that can be used for encapsulating and 3D bioprinting of bone-related SaOS-2 cells. However, the cells, embedded in this matrix, remain in a non-proliferating state. Here we show that addition of an overlay onto the bioprinted ...

journal_title：Biomaterials

authors： Neufurth M,Wang X,Schröder HC,Feng Q,Diehl-Seifert B,Ziebart T,Steffen R,Wang S,Müller WEG

更新日期：2014-10-01 00:00:00

abstract：:Primary canine oral mucosal epithelial cells were cultured on temperature-responsive dishes and cell culture inserts to fabricate transplantable epithelial cell sheets. When 3T3 feeder layers and fetal bovine serum were eliminated from dish culture, the harvested cell sheets became significantly more fragile. In contr...

journal_title：Biomaterials

authors： Murakami D,Yamato M,Nishida K,Ohki T,Takagi R,Yang J,Namiki H,Okano T

更新日期：2006-11-01 00:00:00

abstract：:Liposome is one of the most commonly used drug delivery systems in the world, due to its excellent biocompatibility, satisfactory ability in controlling drug release, and passive targeting capability. However, some drawbacks limit the application of liposomes in clinical, such as problems in transporting, storing, and...

journal_title：Biomaterials

authors： Cheng R,Liu L,Xiang Y,Lu Y,Deng L,Zhang H,Santos HA,Cui W

更新日期：2020-02-01 00:00:00

abstract：:Riboflavin (Rf) and its metabolic analogs flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are essential for normal cellular growth and function. Their intracellular transport is regulated by the riboflavin carrier protein (RCP), which has been shown to be over-expressed by metabolically active cancer...

journal_title：Biomaterials

authors： Jayapaul J,Arns S,Lederle W,Lammers T,Comba P,Gätjens J,Kiessling F

更新日期：2012-12-01 00:00:00

abstract：:Brushite (dicalcium phosphate dihydrate, DCPD, CaHPO4 x 2H2O) was deposited electrolytically from calcium dihydrogen phosphate solution with and without potassium chloride (KCl) as a supporting electrolyte. The kinetics of brushite transformation to hydroxyapatite (HA, Ca5(PO4)3OH) in the presence of calcium and prote...

journal_title：Biomaterials

authors： Kumar M,Xie J,Chittur K,Riley C

更新日期：1999-08-01 00:00:00

abstract：:Periprosthetic tissues observed at sites of loose total joint implants exhibit abundant macrophages, lymphocytes, fibroblasts and particulate debris. Macrophages phagocytose orthopaedic debris and release proinflammatory cytokines, chemokines, matrix metalloproteinases and other substances. In addition, other cell typ...

journal_title：Biomaterials

authors： Trindade MC,Lind M,Sun D,Schurman DJ,Goodman SB,Smith RL

更新日期：2001-02-01 00:00:00

abstract：:Previous in vivo studies have shown a limited potential for vertical bone regeneration using osteoconductive scaffolds alone. In the present study, we investigated whether the association of adipose-derived adult stem cells (ASCs) with anorganic bovine bone (ABB) scaffold improved bone formation and implant osseointeg...

journal_title：Biomaterials

authors： Pieri F,Lucarelli E,Corinaldesi G,Aldini NN,Fini M,Parrilli A,Dozza B,Donati D,Marchetti C

更新日期：2010-05-01 00:00:00

abstract：:Two types of isoelastic endosseous dental implants were produced and their functionality was tested. One type consisted of a porous sintered TiTa30 alloy, the other had a special surface structure consisting of titanium wire loops. Their mechanical properties were optimized by the production parameter (sintering and d...

journal_title：Biomaterials

authors： Breme J,Biehl V,Schulte W,d'Hoedt B,Donath K

更新日期：1993-10-01 00:00:00

abstract：:Matrix systems used to study complex three-dimensional (3D) cellular processes like mammary epithelial tissue morphogenesis and tumorigenesis ex vivo often require ill-defined biological components, which lead to poor reproducibility and a lack of control over physical parameters. In this study, a well-defined, tunabl...

journal_title：Biomaterials

authors： Nowak M,Freudenberg U,Tsurkan MV,Werner C,Levental KR

更新日期：2017-01-01 00:00:00

abstract：OBJECT:Allogenic human fascia lata used in neurosurgery, as dura mater substitute, can be associated with a risk of viral and bacterial transmission. Chemical and physical procedures, developed to inactivate virus and bacteria, have been applied to fascia lata. The aim of this study consists in the evaluation of the bi...

journal_title：Biomaterials

authors： Dufrane D,Cornu O,Delloye C,Schneider YJ

更新日期：2002-07-01 00:00:00

abstract：:Two kinds of micelles containing Rhodamine B were prepared by a solvent evaporation method. One (Lac-f-micelles: lactose-free micelles) was from a Rhodamine-containing copolymer, poly(ethylene glycol)-b-poly(l-lactide-co-2,2-dihydroxylmethyl-propylene carbonate/Rhodamine) [PEG(5000)-b-P(LA(4000)-co-DHP(600)/Rhodamine)...

journal_title：Biomaterials

authors： Ma P,Liu S,Huang Y,Chen X,Zhang L,Jing X

更新日期：2010-03-01 00:00:00

abstract：:A practical method of photocrosslinking high molecular weight poly(trimethylene carbonate)(PTMC) is presented. Flexible, elastomeric and biodegradable networks could be readily prepared by UV irradiating PTMC films containing pentaerythritol triacrylate (PETA) and a photoinitiator. The network characteristics, mechani...

journal_title：Biomaterials

authors： Bat E,Kothman BH,Higuera GA,van Blitterswijk CA,Feijen J,Grijpma DW

更新日期：2010-11-01 00:00:00

abstract：:Radiolabeled nanomaterials, especially those with ultra-small structures, have been the research focus in recent years, and thus may open up new prospects for clinical diseases theranostics. Herein, fluorinated Pd nanosheets labeled with Gd or radionuclides are developed as multimodal platforms for tumor theranostics....

journal_title：Biomaterials

authors： Guo Z,Chen M,Peng C,Mo S,Shi C,Fu G,Wen X,Zhuang R,Su X,Liu T,Zheng N,Zhang X

更新日期：2018-10-01 00:00:00

abstract：:Bioceramic coatings, created by the high velocity oxy-fuel combustion spraying of hydroxyapatite (HA) powders onto commercially pure titanium, were characterized in order to determine whether this relatively new coating process can be successfully applied to bioceramic coatings of orthopaedic and dental implants. Four...

journal_title：Biomaterials

authors： Haman JD,Lucas LC,Crawmer D

更新日期：1995-02-01 00:00:00

abstract：:Most part of pH- and temperature-sensitive microspheres used for the controlled delivery of drugs are not biodegradable. Therefore, the aim of this work is to prepare pH- and temperature-sensitive microspheres from biodegradable and biocompatible natural polymers. Pullulan microspheres were prepared by suspension cros...

journal_title：Biomaterials

authors： Fundueanu G,Constantin M,Ascenzi P

更新日期：2008-06-01 00:00:00

abstract：:Specific molecularly imprinted polymers (MIPs) for the drug reserpine (RES) using methacrylic acid (MAA) as the functional monomer were developed and characterised for the first time in this study. Evaluation of the various polymers by binding assays indicated that the optimum ratio of functional monomer to template w...

journal_title：Biomaterials

authors： Shi X,Wu A,Qu G,Li R,Zhang D

更新日期：2007-09-01 00:00:00

abstract：:Although PEGylated liposome-based drug delivery systems hold great promising applications for cancer therapy due to their prolonged blood circulation time, PEGylation significantly reduces their cellular uptake, which markedly impairs the in vivo tumor retention and antitumor efficiency of drug-loaded liposomes. Most ...

journal_title：Biomaterials

authors： Li Y,Liu R,Yang J,Shi Y,Ma G,Zhang Z,Zhang X

更新日期：2015-02-01 00:00:00

abstract：:The aim of this study was to identify and quantify potential regional and directional variations in the quasistatic uniaxial mechanical properties of the passive urinary bladder wall. Overall, the lower body and trigone regions demonstrated the highest degree of directional anisotropy, whereas the ventral region demon...

journal_title：Biomaterials

authors： Korossis S,Bolland F,Southgate J,Ingham E,Fisher J

更新日期：2009-01-01 00:00:00

abstract：:Porous biomaterials designed to support cellular infiltration and tissue formation play a critical role in implant fixation and engineered tissue repair. The purpose of this Leading Opinion Paper is to advocate the use of high resolution 3D imaging techniques as a tool to quantify extracellular matrix formation and va...

journal_title：Biomaterials

authors： Guldberg RE,Duvall CL,Peister A,Oest ME,Lin AS,Palmer AW,Levenston ME

更新日期：2008-10-01 00:00:00

abstract：:To investigate the roles of composition and characteristics of titanium surface oxides in cellular behaviour of osteoblasts, the surface oxides of titanium were modified in composition and topography by anodic oxidation in two kinds of electrolytes, (a) 0.2 M H(3)PO(4), and (b) 0.03 M calcium glycerophosphate (Ca-GP) ...

journal_title：Biomaterials

authors： Zhu X,Chen J,Scheideler L,Reichl R,Geis-Gerstorfer J

更新日期：2004-08-01 00:00:00

abstract：:The calcination and natural sintering of calcium deficient hydroxyapatite powders Ca(10-x)(PO4)(6-x)(HPO4)x(OH)(2-x) (with 0 < or = x < or = 1) were studied. For temperature below 700 degrees C, particle coalescence occurs without densification. The particle coalescence is associated with a reduction of the specific s...

journal_title：Biomaterials

authors： Raynaud S,Champion E,Bernache-Assollant D

更新日期：2002-02-01 00:00:00