Abstract:
:Gelatin and dextran were blended and crosslinked to form enzymatically degradable interpenetrating polymeric networks (IPNs) as materials for degradable implants. Several crosslinking methods were investigated including treatment with glyceraldehyde, thermal hardening, and chelation of dextran by divalent metal cations. IPNs were characterized by an equilibrium swelling method. Gelatin/dextran IPNs were stable at 25 degrees C and reached peak volume equilibrium swelling ratios up to 17 and peak weight swelling ratios up to 15. When swollen at 37 degrees C, the gels dissolved denoting that a network had been formed by physical and not chemical crosslinks.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Kosmala JD,Henthorn DB,Brannon-Peppas Ldoi
10.1016/s0142-9612(00)00057-0keywords:
subject
Has Abstractpub_date
2000-10-01 00:00:00pages
2019-23issue
20eissn
0142-9612issn
1878-5905pii
S0142-9612(00)00057-0journal_volume
21pub_type
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