Effect of adenosine-5'-triphosphate-3'-diphosphate and related nucleoside polyphosphates on the spore germination of Streptomyces galilaeus.

Abstract:

:Exogenous addition of adenosine- and guanosine 5'-(di- and tri) phosphate 3'-diphosphate (pppApp, ppApp, pppGpp and ppGpp) at the concentration of 0.5 mM inhibits spore germination of Streptomyces galilaeus ATCC 31133. This reversible inhibitory effect appeared to be at the transcriptional level, and also depends on the phase of spore germination; pppApp inhibited more strongly RNA synthesis in the period of the germ tube emergence than the early stage of germination. No inhibitory effect was observed with normal purine and pyrimidine nucleosides, nucleotides, pApp, pGpp, cyclic AMP and pyrophosphoric acid at the concentration of 0.1 - 1.0 mM.

journal_name

Arch Microbiol

journal_title

Archives of microbiology

authors

Hamagishi Y,Tone H,Oki T,Inui T

doi

10.1007/BF00446889

subject

Has Abstract

pub_date

1980-04-01 00:00:00

pages

285-9

issue

3

eissn

0302-8933

issn

1432-072X

journal_volume

125

pub_type

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