Abstract:
:Because of the close anatomical association between the ventricles, the volume of one ventricle can directly affect the volume and pressure within the other ventricle. To study the mechanical coupling between the ventricles, we modeled the right and left ventricles as a two-compartment model with right wall (Crw), septal (Cs), and left wall (Clw) compliances. Based on the balances of forces across the septum, four equations were obtained to predict the transfer of pressure (P) and volume (V) information from one ventricle to another. The validity of the theoretical analysis was tested first in a physical model and then in a post-mortem heart preparation. The standard errors of estimate comparing the predicted to measured values were low for both the physical model and the post-mortem heart data. All values were significantly related (P less than 0.05) with r greater than 0.89. The results show excellent correlation between predicted and measured values. This model provides a better understanding of ventricular interdependence and may help to predict effects of hypertrophy and/or myocardial ischemia on ventricular interdependence.
journal_name
Basic Res Cardioljournal_title
Basic research in cardiologyauthors
Santamore WP,Shaffer T,Hughes Ddoi
10.1007/BF01907759subject
Has Abstractpub_date
1986-09-01 00:00:00pages
529-38issue
5eissn
0300-8428issn
1435-1803journal_volume
81pub_type
杂志文章abstract::Implicit in attempts to characterize and purify biologically active factors is the premise that the bioassay system employed will show a progressive increase in the response as the concentration of the responsible factor increases. We employed the hamster cheek pouch to assay the neovascularization potential of growth...
journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/BF01907406
更新日期:1986-05-01 00:00:00
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journal_title:Basic research in cardiology
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更新日期:1998-04-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
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journal_title:Basic research in cardiology
pub_type: 杂志文章,评审
doi:10.1007/s003950050201
更新日期:1998-01-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/s00395-017-0626-1
更新日期:2017-07-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/BF01908204
更新日期:1989-09-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章,评审
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更新日期:1998-01-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/s003950050181
更新日期:2000-06-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/s00395-016-0538-5
更新日期:2016-03-01 00:00:00
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doi:10.1007/s00395-004-0482-7
更新日期:2004-09-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/BF01908059
更新日期:1981-11-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/BF02650875
更新日期:1989-07-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章,评审
doi:10.1007/978-3-642-72477-0_5
更新日期:1992-01-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/978-3-662-11289-2_25
更新日期:1987-01-01 00:00:00
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doi:10.1007/s00395-019-0743-0
更新日期:2019-08-06 00:00:00
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更新日期:2010-03-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/BF01907422
更新日期:1986-01-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/s00395-016-0592-z
更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2001-07-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
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更新日期:1998-01-01 00:00:00
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更新日期:2003-11-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00395-017-0619-0
更新日期:2017-05-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/BF01906525
更新日期:1978-09-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/BF02190601
更新日期:1991-05-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/BF00788873
更新日期:1993-11-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章,评审
doi:10.1007/s003950170062
更新日期:2001-04-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/BF02023598
更新日期:1977-07-01 00:00:00
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journal_title:Basic research in cardiology
pub_type: 杂志文章
doi:10.1007/s00395-004-0498-4
更新日期:2005-01-01 00:00:00