Abstract:
:Three pH electrodes in clinical use were examined--(1) antimony electrode with remote reference electrode (Synectics 0011), (2) glass electrode with remote reference electrode (Microelectrodes Inc. MI 506) and (3) combined glass electrode with integral reference electrode (Radiometer GK2801C). In vitro studies showed that both glass electrodes were similar and superior to the antimony electrode with respect to response time, drift, and sensitivity. The effect of the siting of the reference electrode on the recorded pH was examined in five human volunteers. The pH reading using a remote skin reference electrode was higher by a mean of 0.3 pH units (range 0.0-0.6) in the stomach, lower by 0.65 pH units (0.5-0.8) in the duodenum and lower by 0.3 pH units (0.0-0.6) in the oesophagus than that simultaneously obtained with an intraluminal reference electrode. Buccal reference electrodes gave similar readings to skin. Combined reference and glass pH electrodes are recommended for 24-hour ambulatory pH monitoring.
journal_name
Gutjournal_title
Gutauthors
McLauchlan G,Rawlings JM,Lucas ML,McCloy RF,Crean GP,McColl KEdoi
10.1136/gut.28.8.935subject
Has Abstractpub_date
1987-08-01 00:00:00pages
935-9issue
8eissn
0017-5749issn
1468-3288journal_volume
28pub_type
杂志文章相关文献
GUT文献大全abstract:BACKGROUND AND AIMS:Although peroxisome proliferator activated receptor gamma (PPARgamma) agonists have been implicated in differentiation and growth inhibition of cancer cells, the potential therapeutic and chemopreventive effects on gastric cancer are poorly defined. We examined the in vitro and in vivo effects of PP...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.2003.021105
更新日期:2004-03-01 00:00:00
abstract::Escherichia coli strains isolated from patients with Crohn's disease (CD) with chronic ileal lesions (n=14), early endoscopic recurrent lesions (n=20), without endoscopic recurrence (n=7), and controls (n=21) were compared by ribotyping. The dendrogram generated by 50 ribotype profile analysis revealed a large cluster...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.48.3.320
更新日期:2001-03-01 00:00:00
abstract::Diverticulitis affects the right side of the colon more commonly than the left side in the Far East. A consecutive series of 35 patients (mean age 44 years) with right sided diverticulitis seen at this hospital is presented. All had localised pain in the right iliac fossa but systemic upset was uncommon. All but one w...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.33.4.547
更新日期:1992-04-01 00:00:00
abstract::Rosetting techniques were used to estimate T and B cell subpopulations in the peripheral blood in patients with treated and untreated adult coeliac disease and in control subjects. In patients with untreated coeliac disease, T cell numbers were significantly lower than in controls or treated patients, although there w...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.19.10.892
更新日期:1978-10-01 00:00:00
abstract::Gastric antral vascular ectasia ('water melon stomach') is a poorly documented cause of occult upper gastrointestinal blood loss. We describe a case which emphasises the clinical and pathological difficulties that can be encountered in making this elusive diagnosis. ...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.32.8.954
更新日期:1991-08-01 00:00:00
abstract::Management strategies for reflux disease are very different from those for dyspepsia and so differentiating between patients with "true" dyspepsia and those whose primary symptom is heartburn is a key step in their management. This separation has become more clear during the last decade as insights into reflux disease...
journal_title:Gut
pub_type: 杂志文章,评审
doi:10.1136/gut.50.suppl_4.iv17
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Data on genetic susceptibility to sporadic gastric carcinoma have been published at a growing pace, but to date no comprehensive overview and quantitative summary has been available. METHODS:We conducted a systematic review and meta-analysis of the evidence on the association between DNA variation and risk ...
journal_title:Gut
pub_type: 杂志文章,meta分析,评审
doi:10.1136/gutjnl-2015-309168
更新日期:2015-08-01 00:00:00
abstract::The influence of carbenoxolone on the synthesis of glycoproteins in the surface mucous cells and the production of new cells in the rat gastric mucosa was studied by means of a vascular perfusion system. The rate of incorporation of tritiated galactose, glucosamine, serine, and sulphate in surface mucous cells, studie...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.22.10.782
更新日期:1981-10-01 00:00:00
abstract::The effect of the unconjugated bile acids, cholic, deoxycholic, chenodeoxycholic, and ursodeoxycholic acids, and of the conjugated bile acid taurocholic acid on the mucosal-to-serosal transport and tissue uptake of the naturally occurring folate derivative, 5-methyltetrahydrofolate (5-CH3H4PteGlu) was examined in ever...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.25.12.1376
更新日期:1984-12-01 00:00:00
abstract::A histochemical study of conjugated and total bilirubin was made on liver biopsies of 150 patients. Three types of cholestasis were defined: type I, characterized by the presence of intracellular pigment granules in the hepatocytes; type II, showing intracellular granules and extracellular thrombi (this group may be s...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.11.6.516
更新日期:1970-06-01 00:00:00
abstract:BACKGROUND:The efficacy of a levofloxacin-based regimen as the first-line treatment and a clarithromycin-based regimen as the second-line treatment for Helicobacter pylori infection remains unknown. The aim of this study was to assess the eradication rates of these two regimens using different administration sequences....
journal_title:Gut
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/gut.2009.198309
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:The colonic inner mucus layer protects us from pathogens and commensal-induced inflammation, and has been shown to be defective in active UC. The aim of this study was to determine the underlying compositional alterations, their molecular background and potential contribution to UC pathogenesis. DESIGN:In th...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2018-317571
更新日期:2019-12-01 00:00:00
abstract::We have reviewed the outcome of all patients undergoing their first intestinal resection for Crohn's disease at this hospital between 1970 and 1987. Recurrence rates, defined by recurrent intestinal symptoms and radiological confirmation of mucosal disease, were calculated using survival analysis. Age, sex, anatomical...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.32.5.491
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVE:Chronic HBV infection affects more than 250 million people worldwide and remains a global healthcare problem in part because we lack curative treatment. Sustained viral control requires HBV-specific T cells, but these become functionally impaired in chronic infection. Clinical evidence indicates that function...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2018-316644
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:The mechanisms of aspirin induced gastroduodenal injury are not fully understood. Aspirin induces the release of reactive oxygen metabolites in animal models, which may contribute to mucosal injury. AIMS:To investigate the effects of aspirin administered with placebo or antioxidants on gastric mucosal react...
journal_title:Gut
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/gut.38.4.518
更新日期:1996-04-01 00:00:00
abstract::The value of four tests to detect occult alimentary blood loss has been compared in normal subjects, in patients with and without alimentary disease, and in patients with congestive heart failure, and the sensitivities of these tests have been compared using suspensions of blood alone and blood in faeces. The Occultes...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.2.1.75
更新日期:1961-03-01 00:00:00
abstract:BACKGROUND:Autoantibodies against transglutaminase 2 (TG2) are thought to be responsible for the endomysial (EMA), reticulin (ARA), and jejunal antibody (JEA) tissue binding of serum samples from coeliac patients but the exclusive role of TG2 in these staining patterns has not yet been established. AIMS:To evaluate wh...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.52.2.199
更新日期:2003-02-01 00:00:00
abstract::The cholesteryl-14C-octanoate breath test was used to monitor the intraluminal enzymatic activity of pancreatin preparations in six patients with severe pancreatic insufficiency. Conventional enzyme replacement, with cimetidine as an adjunct, was compared to supplementation with enteric coated microspheres. In healthy...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.31.11.1324
更新日期:1990-11-01 00:00:00
abstract:BACKGROUND:This is a consensus developed by a group of expert endoscopists aiming to standardise the preparation, process and endoscopic procedural steps for diagnosis of early upper gastrointestinal (GI) cancers. METHOD:The Delphi method was used to develop consensus statements through identification of clinical ques...
journal_title:Gut
pub_type: 共识发展会议,杂志文章
doi:10.1136/gutjnl-2018-317111
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:Thiopurines are widely used as maintenance therapy in inflammatory bowel disease (IBD) but the evidence base for their use is sparse and their role increasingly questioned. Using the largest series reported to date, we assessed the long-term effectiveness of thiopurines in ulcerative colitis (UC) and Crohn's ...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2019-320185
更新日期:2020-10-01 00:00:00
abstract::The effect of 28 days' continuous administration of oral indomethacin on gastroduodenal morphology, gastric mucosal blood flow, and gastric mucosal prostaglandin E2 (PGE2) metabolism in man was studied to define further the mechanisms of mucosal injury induced by indomethacin. Indomethacin caused acute gastroduodenal ...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.33.2.164
更新日期:1992-02-01 00:00:00
abstract::This study confirms previous reports that satisfactory gastric acid secretory responses to intravenous administration of histamine, carbachol, and gastrin can be obtained. Bilateral castration of the male rats significantly reduced acid gastric secretory responses to carbachol but not to histamine. Overiectomized rats...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.11.8.641
更新日期:1970-08-01 00:00:00
abstract::Quantitative and qualitative disturbances in faecal flora suggest a role for enteric bacteria and their products in the pathogenesis of inflammatory bowel disease (IBD). This study investigated the hypothesis that systemically circulating endotoxins are of pathogenic significance in IBD by measuring antibody, cytokine...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.36.6.897
更新日期:1995-06-01 00:00:00
abstract::Fourteen apparently healthy patients with ileostomies were found to be depleted of total exchangeable sodium and potassium, but had normal serum electrolyte concentrations and normal extracellular fluid and total body water volumes. The low exchangeable sodium and potassiums were thus primarily due to depletion of the...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.19.6.563
更新日期:1978-06-01 00:00:00
abstract::Several methods for the preparation of cell suspensions from human gastrointestinal mucosa were investigated. Satisfactory suspensions were obtained by incubating tissue fragments in a solution of collagenase and hyaluronidase overnight at 4 degrees C followed by 30 minutes at 37 degrees C. The resulting suspension co...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.19.10.898
更新日期:1978-10-01 00:00:00
abstract::The epithelial-mesenchymal interface of the intestinal mucosa obviously plays an important role in supporting the mucosal architecture. Its significance for the process of migration and differentiation of the epithelial cells remains to be resolved. It consists of a basement membrane, the anchoring zone and the subepi...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.28.suppl.143
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVES:National guidelines for the management of irritable bowel syndrome (IBS) recommend that psychological therapies should be considered, but their relative efficacy is unknown, because there have been few head-to-head trials. We performed a systematic review and network meta-analysis to try to resolve this unce...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gutjnl-2020-321191
更新日期:2020-08-01 00:00:00
abstract::In a study of low dose interferon alfa-2b in 587 patients expected to show a good response to treatment, 76-87% patients in different countries had alanine amino-transferase activities returned to normal after four months' treatment, 49-72% were negative for hepatitis B virus (HBV)-DNA, 51-66% were negative for hepati...
journal_title:Gut
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1136/gut.34.2_suppl.s99
更新日期:1993-01-01 00:00:00
abstract::The effect of a new complex oligosaccharide exhibiting potent inhibitory action on alpha-glucoside hydrolases on intestinal absorption of sucrose in man was tested by constant in vivo perfusion of the jejunum. At concentrations of 4.65 or 15.5 X 10(-6)M the alpha-glucosidehydrolase inhibitor (alpha-GHI) markedly inhib...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.20.9.750
更新日期:1979-09-01 00:00:00
abstract::Three methods for dispensing nutritional solutions are compared in 48 patients with gastrointestinal diseases on intravenous nutrition during 3582 days. The protocol for intravenous nutrition applied by the nursing team and the solutions used were the same in the three groups. In group A standard bottles were used, wh...
journal_title:Gut
pub_type: 杂志文章
doi:10.1136/gut.23.4.297
更新日期:1982-04-01 00:00:00