Abstract:
:Lysine-vasopressin (LVP) at different concentrations (2 ng, 200 pg) was injected into the lateral ventricle and cisterna magna. The effect on hypothalamic self-stimulation was studied in rats. LVP (2 ng) decreased the self-stimulation rate after intracerebroventricular and cisternal application. Injection of 200 pg LVP diminished the self-stimulation rate after cisternal administration only. The findings suggest that the site of peptide administration is of decisive importance to vasopressin-induced effects. Both biochemical factors and the interaction between behaviour and vegetative nervous system should be taken into consideration when interpreting changes in self-stimulation as induced by vasopressin applied to the CSF space.
journal_name
Neuropeptidesjournal_title
Neuropeptidesauthors
Günther O,Schwarzberg Hdoi
10.1016/s0143-4179(87)90119-3subject
Has Abstractpub_date
1987-11-01 00:00:00pages
361-7issue
4eissn
0143-4179issn
1532-2785pii
S0143-4179(87)90119-3journal_volume
10pub_type
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