Synthesis and tumour cell uptake studies of gadolinium(III)-phosphonium complexes.

abstract：:Cardiac energy metabolism must cope with early postnatal changes in tissue oxygen tensions, hemodynamics, and cell proliferation to sustain development. Here, we tested the hypothesis that proliferating neonatal cardiomyocytes are dependent on high oxidative energy metabolism. We show that energy-related gene expressi...

journal_title：Scientific reports

authors： de Carvalho AETS,Bassaneze V,Forni MF,Keusseyan AA,Kowaltowski AJ,Krieger JE

更新日期：2017-11-13 00:00:00

abstract：:Time-series metabolomics studies can provide insight into the dynamics of disease development and facilitate the discovery of prospective biomarkers. To improve the performance of early risk identification, a new strategy for analyzing time-series data based on dynamic networks (ATSD-DN) in a systematic time dimension...

journal_title：Scientific reports

authors： Huang X,Zeng J,Zhou L,Hu C,Yin P,Lin X

更新日期：2016-08-31 00:00:00

abstract：:Ionotropic glutamate receptors (iGluRs) are responsible for most of the fast excitatory communication between neurons in our brain. The GluD2 receptor is a puzzling member of the iGluR family: It is involved in synaptic plasticity, plays a role in human diseases, e.g. ataxia, binds glycine and D-serine with low affini...

journal_title：Scientific reports

authors： Tapken D,Steffensen TB,Leth R,Kristensen LB,Gerbola A,Gajhede M,Jørgensen FS,Olsen L,Kastrup JS

更新日期：2017-04-07 00:00:00

abstract：:Pavlovské vrchy Hills represent a distinctive elevation near the Czech-Austrian border where the active, dormant and relict landslides cover 12% of the area. Here we focused on the chronology of landsliding in this area using geological, archaeological and historical evidence. The earliest records of landsliding were ...

journal_title：Scientific reports

authors： Bíl M,Krejčí O,Dolák L,Krejčí V,Martínek J,Svoboda J

更新日期：2020-01-22 00:00:00

abstract：:This study aimed to optimize the applicability of an immunoliposome-based immunomagnetic concentration and separation assay to facilitate rapid detection of Cronobacter sakazakii in powdered infant formula (PIF). To determine the detection limit, specificity, and pre-enrichment incubation time (0, 4, 6, and 8 h), assa...

journal_title：Scientific reports

authors： Shukla S,Lee G,Song X,Park JH,Cho H,Lee EJ,Kim M

更新日期：2016-10-10 00:00:00

abstract：:Recent paleoclimatic studies suggest that changes in the tropical rainbelt across the Atlantic Ocean during the past two millennia are linked to a latitudinal shift of the Intertropical Convergence Zone (ITCZ) driven by the Northern Hemisphere (NH) climate. However, little is known regarding other potential drivers th...

journal_title：Scientific reports

authors： Utida G,Cruz FW,Etourneau J,Bouloubassi I,Schefuß E,Vuille M,Novello VF,Prado LF,Sifeddine A,Klein V,Zular A,Viana JCC,Turcq B

更新日期：2019-02-08 00:00:00

abstract：:The use of lithium (Li) metal anodes has been reconsidered because of the necessity for a higher energy density in secondary batteries. However, Li metal anodes suffer from 'dead' Li formation and surface deactivation which consequently form a porous layer of redundant Li aggregates. In this work, a fibrous metal felt...

journal_title：Scientific reports

authors： Lee H,Song J,Kim YJ,Park JK,Kim HT

更新日期：2016-08-03 00:00:00

abstract：:Evaluation of the effect of different parameters for designing a non-viral vector in gene delivery systems has great importance. In this manner, 2D crystals, precisely layered double hydroxides, have attracted the attention of scientists due to their significant adjustability and low-toxicity and low-cost preparation ...

journal_title：Scientific reports

authors： Rabiee N,Bagherzadeh M,Ghadiri AM,Salehi G,Fatahi Y,Dinarvand R

更新日期：2020-11-26 00:00:00

abstract：:Various techniques are commonly used to produce nano-crystalline NiAl2O4 materials; however, their practical applications in the microwave region remain very limited. In this work, flexible substrates for metamaterials containing two different concentrations of NiAl2O4 (labelled Ni36 and Ni42) have been synthesised us...

journal_title：Scientific reports

authors： Rahman MA,Ahamed E,Faruque MRI,Islam MT

更新日期：2018-10-08 00:00:00

abstract：:Accumulating evidence has indicated that immune regulatory cells are involved in the establishment of tumoral immune evasion. However, the role of regulatory B cells (Bregs) in this remains unclear. Here, we identified a role for Bregs in immune evasion in gastric cancer (GC) patients. The frequency of peripheral Breg...

journal_title：Scientific reports

authors： Murakami Y,Saito H,Shimizu S,Kono Y,Shishido Y,Miyatani K,Matsunaga T,Fukumoto Y,Ashida K,Sakabe T,Nakayama Y,Fujiwara Y

更新日期：2019-09-11 00:00:00

abstract：:Little is known about the feeding behavior of hematophagous insects that require plant sugar to complete their life cycles. We studied plant feeding of Lutzomyia longipalpis sand flies, known vectors of Leishmania infantum/chagasi parasites, in a Brazilian city endemic with visceral leishmaniasis. The DNA barcode tech...

journal_title：Scientific reports

authors： Lima LHGM,Mesquita MR,Skrip L,de Souza Freitas MT,Silva VC,Kirstein OD,Abassi I,Warburg A,Balbino VQ,Costa CHN

更新日期：2016-07-20 00:00:00

abstract：:RNA-binding proteins are key regulators of post-transcriptional processes such as alternative splicing and mRNA stabilization. Rbm24 acts as a regulator of alternative splicing in heart and skeletal muscle, and is essential for sarcomere assembly. Homozygous inactivation of Rbm24 in mice disrupts cardiac development a...

journal_title：Scientific reports

authors： de Groot NE,van den Hoogenhof MMG,Najafi A,van der Made I,van der Velden J,Beqqali A,Pinto YM,Creemers EE

更新日期：2020-05-06 00:00:00

abstract：:The non-invasive high-resolution spatial mapping of cell metabolism within tissues could provide substantial advancements in assessing the efficacy of stem cell therapy and understanding tissue development. Here, using two-photon excited fluorescence microscopy, we elucidate the relationships among endogenous cell flu...

journal_title：Scientific reports

authors： Quinn KP,Sridharan GV,Hayden RS,Kaplan DL,Lee K,Georgakoudi I

更新日期：2013-12-05 00:00:00

abstract：:Antimicrobial resistance is rapidly expanding, in a large part due to mobile genetic elements. We screened 94 fecal fluoroquinolone-resistant Escherichia coli isolates from Nigeria for six plasmid-mediated quinolone resistance (PMQR) genes. Sixteen isolates harbored at least one of the PMQR genes and four were positiv...

journal_title：Scientific reports

authors： Monárrez R,Braun M,Coburn-Flynn O,Botelho J,Odetoyin BW,Otero-Vera JI,Quartey NKE,Peixe L,Aboderin AO,Okeke IN

更新日期：2019-12-23 00:00:00

abstract：:Optical clearing methods can facilitate deep optical imaging in biological tissue by reducing light scattering and this has enabled accurate three-dimensional signal visualization and quantification of complex biological structures. Unfortunately, existing optical clearing approaches present a compromise between maxim...

journal_title：Scientific reports

authors： Chen L,Li G,Li Y,Li Y,Zhu H,Tang L,French P,McGinty J,Ruan S

更新日期：2017-09-22 00:00:00

abstract：:The fluorination of p-type metal phthalocyanines produces n-type semiconductors, allowing the design of organic electronic circuits that contain inexpensive heterojunctions made from chemically and thermally stable p- and n-type organic semiconductors. For the evaluation of close to intrinsic transport properties, hig...

journal_title：Scientific reports

authors： Jiang H,Ye J,Hu P,Wei F,Du K,Wang N,Ba T,Feng S,Kloc C

更新日期：2014-12-19 00:00:00

abstract：:Antibiotics are unable to remove biofilms from surgical implants. This high antibiotic tolerance is related to bacterial persisters, a sub-population of bacteria phenotypically tolerant to antibiotics secondary to a reduced metabolic state. WLBU2 is an engineered cationic amphipathic peptide designed to maximize antim...

journal_title：Scientific reports

authors： Mandell JB,Deslouches B,Montelaro RC,Shanks RMQ,Doi Y,Urish KL

更新日期：2017-12-22 00:00:00

abstract：:From biomarkers to drug carriers, Extracellular Vesicles (EVs) are being used successfully in numerous applications. However, while the subject has been steadily rising in popularity, current methods of isolating EVs are lagging behind, incapable of isolating EVs at a high enough quantity or quality while also requiri...

journal_title：Scientific reports

authors： Kırbaş OK,Bozkurt BT,Asutay AB,Mat B,Ozdemir B,Öztürkoğlu D,Ölmez H,İşlek Z,Şahin F,Taşlı PN

更新日期：2019-12-16 00:00:00

abstract：:This study examined the performance and photo-bias stability of double-channel ZnSnO/InZnO (ZTO/IZO) thin-film transistors. The field-effect mobility (μFE) and photo-bias stability of the double-channel device were improved by increasing the thickness of the front IZO film (t(int)) compared to the single-ZTO-channel d...

journal_title：Scientific reports

authors： Jung HY,Kang Y,Hwang AY,Lee CK,Han S,Kim DH,Bae JU,Shin WS,Jeong JK

更新日期：2014-01-20 00:00:00

abstract：:Tumor tissue mutational burden (TMB) has emerged as a promising predictive biomarker for immune checkpoint therapy. Measuring TMB from circulating tumor DNA (ctDNA) found in plasma is attractive in tissue-constrained indications. We compared the performance of two plasma-based commercial TMB assays including the effec...

journal_title：Scientific reports

authors： Qiu P,Poehlein CH,Marton MJ,Laterza OF,Levitan D

更新日期：2019-01-14 00:00:00

abstract：:Mitochondria increase in number by the fission of existing mitochondria. Mitochondrial fission is needed to provide mitochondria to daughter cells during cell division. In Arabidopsis thaliana, four kinds of genes have been reported to be involved in mitochondrial fission. Two of them, DRP3 (dynamin-related protein3) ...

journal_title：Scientific reports

authors： Nagaoka N,Yamashita A,Kurisu R,Watari Y,Ishizuna F,Tsutsumi N,Ishizaki K,Kohchi T,Arimura SI

更新日期：2017-07-04 00:00:00

abstract：:Many deltas are likely undergoing net erosion because of rapid decreases in riverine sediment supply and rising global sea levels. However, detecting erosion in subaqueous deltas is usually difficult because of the lack of bathymetric data. In this study, by comparing bathymetric data between 1981 and 2012 and surfici...

journal_title：Scientific reports

authors： Luo XX,Yang SL,Wang RS,Zhang CY,Li P

更新日期：2017-02-01 00:00:00

abstract：:Macroautophagy, the degradation of cytoplasmic content by lysosomal fusion, is an evolutionary conserved process promoting homeostasis and intracellular defence. Macroautophagy is initiated primarily by a complex containing ULK1 or ULK2 (two paralogs of the yeast Atg1 protein). To understand the differences between UL...

journal_title：Scientific reports

authors： Demeter A,Romero-Mulero MC,Csabai L,Ölbei M,Sudhakar P,Haerty W,Korcsmáros T

更新日期：2020-07-02 00:00:00

abstract：:CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events such as signaling, adherence and host parasite interactions. In this study we examined the role of...

journal_title：Scientific reports

authors： Alisson-Silva F,Mantuano NR,Lopes AL,Vasconcelos-Dos-Santos A,Vale AM,Costa MM,Cannon JL,Oliveira AC,Todeschini AR

更新日期：2019-06-13 00:00:00

abstract：:A fundamental question in biology is how cell populations evolve into different subtypes based on homogeneous processes at the single cell level. Here we show that population bimodality can emerge even when biological processes are homogenous at the cell level and the environment is kept constant. Our model is based o...

journal_title：Scientific reports

authors： Fernandez-de-Cossio-Diaz J,Mulet R,Vazquez A

更新日期：2019-06-28 00:00:00

abstract：:Newly synthesized mitochondrial precursor proteins have to become unfolded to cross the mitochondrial membranes. This unfolding is achieved primarily by mitochondrial Hsp70 (mtHsp70) for presequence-containing precursor proteins. However, the membrane potential across the inner membrane (ΔΨ) could also contribute to u...

journal_title：Scientific reports

authors： Sato TK,Kawano S,Endo T

更新日期：2019-05-21 00:00:00

abstract：:We used Mendelian randomization to estimate the causal effects of the liver enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyltransferase (GGT), on diabetes and cardiovascular disease, using genetic variants predicting these liver enzymes at genome wide significance applied to exten...

journal_title：Scientific reports

authors： Liu J,Au Yeung SL,Lin SL,Leung GM,Schooling CM

更新日期：2016-12-20 00:00:00

abstract：:Episodic memories are long lasting and full of detail, yet imperfect and malleable. We quantitatively evaluated recollection of short audiovisual segments from movies as a proxy to real-life memory formation in 161 subjects at 15 minutes up to a year after encoding. Memories were reproducible within and across individ...

journal_title：Scientific reports

authors： Tang H,Singer J,Ison MJ,Pivazyan G,Romaine M,Frias R,Meller E,Boulin A,Carroll J,Perron V,Dowcett S,Arellano M,Kreiman G

更新日期：2016-09-30 00:00:00

abstract：:The amount of Paper Board Mill Effluent Treatment Plant Sludge (PBM-ETPS) dumped from paper mills are huge and its conversion into hydrochar for the purpose of energy has broad prospects. This study investigated the optimum conditions for the production of PBM-ETPS derived hydrochar (PBM-ETPSH) through Reponse Surface...

journal_title：Scientific reports

authors： Oumabady S,S PS,Kamaludeen SPB,Ramasamy M,Kalaiselvi P,Parameswari E

更新日期：2020-01-21 00:00:00

abstract：:The proinflammatory cytokine Interleukin 17A (hereafter named IL-17A) or IL-17A producing cells are elevated in breast tumors environment and correlate with poor prognosis. Increased IL-17A is associated with ER(-) or triple negative tumors and reduced Disease Free Survival. However, the pathophysiological role of IL-...

journal_title：Scientific reports

authors： Cochaud S,Giustiniani J,Thomas C,Laprevotte E,Garbar C,Savoye AM,Curé H,Mascaux C,Alberici G,Bonnefoy N,Eliaou JF,Bensussan A,Bastid J

更新日期：2013-12-09 00:00:00