Abstract：
:Episodic memories are long lasting and full of detail, yet imperfect and malleable. We quantitatively evaluated recollection of short audiovisual segments from movies as a proxy to real-life memory formation in 161 subjects at 15 minutes up to a year after encoding. Memories were reproducible within and across individuals, showed the typical decay with time elapsed between encoding and testing, were fallible yet accurate, and were insensitive to low-level stimulus manipulations but sensitive to high-level stimulus properties. Remarkably, memorability was also high for single movie frames, even one year post-encoding. To evaluate what determines the efficacy of long-term memory formation, we developed an extensive set of content annotations that included actions, emotional valence, visual cues and auditory cues. These annotations enabled us to document the content properties that showed a stronger correlation with recognition memory and to build a machine-learning computational model that accounted for episodic memory formation in single events for group averages and individual subjects with an accuracy of up to 80%. These results provide initial steps towards the development of a quantitative computational theory capable of explaining the subjective filtering steps that lead to how humans learn and consolidate memories.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Tang H,Singer J,Ison MJ,Pivazyan G,Romaine M,Frias R,Meller E,Boulin A,Carroll J,Perron V,Dowcett S,Arellano M,Kreiman Gdoi
10.1038/srep30175subject
Has Abstractpub_date
2016-09-30 00:00:00pages
30175issn
2045-2322pii
srep30175journal_volume
6pub_type
杂志文章abstract：:Third-generation sequencing technologies allow to sequence long reads of tens of kbp, that are expected to solve various problems. However, they display high error rates, currently capped around 10%. Self-correction is thus regularly used in long reads analysis projects. We introduce CONSENT, a new self-correction met...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80757-5
更新日期：2021-01-12 00:00:00
abstract：:Application of acute kidney injury (AKI) biomarkers with consideration of nonrenal conditions and systemic severity has not been sufficiently determined. Herein, urinary neutrophil gelatinase-associated lipocalin (NGAL), L-type fatty acid-binding protein (L-FABP) and nonrenal disorders, including inflammation, hypoper...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33077
更新日期：2016-09-08 00:00:00
abstract：:This study was intended to determine the efficacy of nivolumab, we evaluated treatment response with respect to PD-1/PD-L1 SNPs among patients with NSCLC. A total of 50 patients with NSCLC were treated with nivolumab and were also evaluated for PD-1/PD-L1 single nucleotide polymorphisms (SNPs) from plasma DNA. We inve...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45124
更新日期：2017-03-23 00:00:00
abstract：:A new concept for treatment of infections is induction of our own antimicrobial peptides and the presented novel class of inducer, aroylated phenylenediamines (APDs), gives up to 20 to 30-fold induction of the human antimicrobial peptide LL-37, in vitro. In addition, oral administration of an APD in a rabbit model of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36692
更新日期：2016-11-09 00:00:00
abstract：:State of charge (SOC) is a crucial index used in the assessment of electric vehicle (EV) battery storage systems. Thus, SOC estimation of lithium-ion batteries has been widely investigated because of their fast charging, long-life cycle, and high energy density characteristics. However, precise SOC assessment of lithi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61464-7
更新日期：2020-03-13 00:00:00
abstract：:Dry eye disease (DED) is a highly prevalent, ocular disorder characterized by an abnormal tear film and ocular surface. Recent experimental data has suggested that the underlying pathology of DED involves inflammation of the lacrimal functional unit (LFU), comprising the cornea, conjunctiva, lacrimal gland and interco...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17869-y
更新日期：2017-12-13 00:00:00
abstract：:The heterogeneity of metabolic reactions leads to a non-uniform distribution of temperature in different parts of the living cell. The demand to study normal functioning and pathological abnormalities of cellular processes requires the development of new visualization methods. Previously, we have shown that the 35-kDa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45421-7
更新日期：2019-06-20 00:00:00
abstract：:This work aimed to use artificial intelligence to predict subjective refraction from wavefront aberrometry data processed with a novel polynomial decomposition basis. Subjective refraction was converted to power vectors (M, J0, J45). Three gradient boosted trees (XGBoost) algorithms were trained to predict each power ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65417-y
更新日期：2020-05-22 00:00:00
abstract：:Detecting neuroplastic changes during locomotor neurorehabilitation is crucial for independent primal motor behaviours. However, long-term locomotor training-related neuroplasticity remains unexplored. We compared the effects of end-effector robot-assisted gait training (E-RAGT) and bodyweight-supported treadmill trai...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41598-020-69367-3
更新日期：2020-07-27 00:00:00
abstract：:Here, we report direct band gap transition for Gallium Phosphide (GaP) when alloyed with just 1-2 at% antimony (Sb) utilizing both density functional theory based computations and experiments. First principles density functional theory calculations of GaSbxP(1-x) alloys in a 216 atom supercell configuration indicate t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20822
更新日期：2016-02-10 00:00:00
abstract：:The number of magnetoelectric multiferroic materials reported to date is scarce, as magnetic structures that break inversion symmetry and induce an improper ferroelectric polarization typically arise through subtle competition between different magnetic interactions. The (NH4)2[FeCl5(H2O)] compound is a rare case wher...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14475
更新日期：2015-09-29 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-64447-w
更新日期：2020-05-05 00:00:00
abstract：:This work presents a new method for assisting in the identification process of missing persons in several contexts, such as enforced disappearances. We apply a Bayesian technique to incorporate non-genetic variables in the construction of prior information. In that way, we can learn from the already-solved cases of a ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59841-3
更新日期：2020-03-19 00:00:00
abstract：:Although the growth of graphene by chemical vapor deposition is a production technique that guarantees high crystallinity and superior electronic properties on large areas, it is still a challenge for manufacturers to efficiently scale up the production to the industrial scale. In this context, issues related to the p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09811-z
更新日期：2017-08-30 00:00:00
abstract：:Aquatic phytoplankton experience large fluctuations in environmental conditions during seasonal succession and across salinity gradients, but the impact of this variation on their diversity is poorly understood. We examined spatio-temporal variation in nano- and microphytoplankton (> 2 µm) community structure using al...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74428-8
更新日期：2020-10-19 00:00:00
abstract：:The histological spectrum of nonalcoholic fatty liver diseases (NAFLD) ranges from hepatic steatosis to steatohepatitis and fibrosis. Berberine (BBR) is known for its therapeutic effect on obesity, hyperglycaemia and dyslipidaemia; however, its effect on NAFLD has yet to be thoroughly explored. Db/db mice and methioni...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20848
更新日期：2016-02-09 00:00:00
abstract：:Glutamine metabolism and the mechanistic target of rapamycin (mTOR) pathway are activated cooperatively in the differentiation and activation of inflammatory immune cells. But the combined inhibition of both pathways was rarely investigated. This study investigated how inhibiting both glutamine metabolism with 6-diazo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42932-1
更新日期：2019-04-23 00:00:00
abstract：:Diabetes mellitus (DM) is associated with higher risk of tendinopathy, which reduces tolerance to exercise and functional activities and affects lifestyle and glycemic control. Expression of tendon-related genes and matrix metabolism in tenocytes are essential for maintaining physiological functions of tendon. However...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44199
更新日期：2017-03-07 00:00:00
abstract：:The Great East Japan Earthquake on 11 March 2011, caused the release of radioactive materials from the Fukushima Daiichi Nuclear Power Plant (FDNPP), contaminating eastern Japan, particularly in part of Fukushima Prefecture. In 2012 and 2014, the radiocaesium concentration in brown rice did not exceed regulatory level...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20386
更新日期：2016-02-04 00:00:00
abstract：:Metallic glasses are disordered materials that offer the unique ability to perform thermoplastic forming operations at low thermal budget while preserving excellent mechanical properties such as high strength, large elastic strain limits, and wear resistance owing to the metallic nature of bonding and lack of internal...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19530
更新日期：2016-01-20 00:00:00
abstract：:More and more researchers are interested in and focused on how a limited repertoire of antibodies can bind and correspondingly protect against an almost limitless diversity of invading antigens. In this work, a series of 200-ns molecular dynamics (MD) simulations followed by principal component (PC) analysis and free ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36900
更新日期：2016-11-10 00:00:00
abstract：:The quantum Internet enables networking based on the fundamentals of quantum mechanics. Here, methods and procedures of resource prioritization and resource balancing are defined for the quantum Internet. We define a model for resource consumption optimization in quantum repeaters, and a strongly-entangled network str...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78960-5
更新日期：2020-12-28 00:00:00
abstract：:Kefir peptides, generated by kefir grain fermentation of milk proteins, showed positive antioxidant effects, lowered blood pressure and modulated the immune response. In this study, kefir peptide was evaluated regarding their anti-inflammatory effects on particulate matter <4 μm (PM4.0)-induced lung inflammation in NF...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47872-4
更新日期：2019-08-08 00:00:00
abstract：:Surface soil moisture plays a crucial role on the terrestrial water, energy, and carbon cycles. Characterizing its variability in space and time is critical to increase our capability to forecast extreme weather events, manage water resources, and optimize agricultural practices. Global estimates of surface soil moist...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52650-3
更新日期：2019-11-06 00:00:00
abstract：:Molecular imaging is a powerful tool for investigating intracellular signalling, but it is difficult to acquire conventional fluorescence imaging from photoreceptive cells. Here we demonstrated that human opsin5 (OPN5) photoreceptor mediates light-induced Ca(2+) response in human embryonic kidney (HEK293) and mouse ne...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05352
更新日期：2014-06-19 00:00:00
abstract：:The unfolded protein response (UPR) not only resolves endoplasmic reticulum (ER) stress, but also regulates cellular physiological functions. In this study, we first linked the UPR to the physiological roles of brown adipose tissue (BAT). BAT is one of the tissues that control energy homeostasis in the body. Brown adi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16580
更新日期：2015-11-16 00:00:00
abstract：:The aims of this study were to explore whether DNA methylation at INSR and IGF2 mediated the association of prenatal exposure to the Chinese great famine with adulthood waist circumference (WC) and BMI. A total of 235 subjects were selected into the present study from severely affected province and a neighbor province...
journal_title：Scientific reports
pub_type： 历史文章,杂志文章
doi：10.1038/s41598-020-69120-w
更新日期：2020-07-22 00:00:00
abstract：:Electromyography (EMG) is the standard technology for monitoring muscle activity in laboratory environments, either using surface electrodes or fine wire electrodes inserted into the muscle. Due to limitations such as cost, complexity, and technical factors, including skin impedance with surface EMG and the invasive n...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41860-4
更新日期：2019-04-03 00:00:00
abstract：:In quenched disordered out-of-equilibrium many-body colloidal systems, there are important distinctions between the glass transition, which is related to the onset of nonergodicity and loss of low-frequency relaxations caused by crowding, and the jamming transition, which is related to the dramatic increase in elastic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13584-w
更新日期：2017-11-08 00:00:00
abstract：:Early-life social experiences cause lasting changes in behavior and health for a variety of animals including humans, but it is not well understood how social information ''gets under the skin'' resulting in these effects. Adult honey bees (Apis mellifera) exhibit socially coordinated collective nest defense, providin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep15572
更新日期：2015-10-23 00:00:00
