Pretreatment brain volumes can affect the effectiveness of deep brain stimulation in Parkinson's disease patients.

abstract：:Structural materials used for safety critical applications require high strength and simultaneously high resistance against crack growth, referred to as damage tolerance. However, the two properties typically exclude each other and research efforts towards ever stronger materials are hampered by drastic loss of fractu...

journal_title：Scientific reports

authors： Hohenwarter A,Völker B,Kapp MW,Li Y,Goto S,Raabe D,Pippan R

更新日期：2016-09-14 00:00:00

abstract：:Breast cancer (BC) has a higher incidence in young Lebanese woman as compared to the West. We assessed the microRNA (miRNA) microarray profile of tissues derived from Lebanese patients with early BC and performed mRNA-miRNA integration analysis. 173 miRNAs were significantly dysregulated in 45 BC versus 17 normal adja...

journal_title：Scientific reports

authors： Nassar FJ,Talhouk R,Zgheib NK,Tfayli A,El Sabban M,El Saghir NS,Boulos F,Jabbour MN,Chalala C,Boustany RM,Kadara H,Zhang Z,Zheng Y,Joyce B,Hou L,Bazarbachi A,Calin G,Nasr R

更新日期：2017-12-04 00:00:00

abstract：:All-trans-retinoic acid (atRA), the active metabolite of vitamin A, is a critical signaling molecule during embryonic and fetal development and is necessary for maternal health. Fetal exposure to endogenous atRA is tightly regulated during gestation in a tissue specific manner and maternal exposure to exogenous retino...

journal_title：Scientific reports

authors： Topletz AR,Zhong G,Isoherranen N

更新日期：2019-03-15 00:00:00

abstract：:We investigated retinal structure and function in eyes with optic nerve hypoplasia (ONH). Twenty-nine eyes of 18 patients with ONH and 21 eyes of 21 control patients were analyzed. Spectral-domain optical coherence tomography (SD-OCT), full-field electroretinography (FF-ERG), and focal macular ERG (FM-ERG) were perfor...

journal_title：Scientific reports

authors： Katagiri S,Nishina S,Yokoi T,Mikami M,Nakayama Y,Tanaka M,Azuma N

更新日期：2017-02-16 00:00:00

abstract：:Identification of different isomer structures of atomic and molecular clusters has long been a challenging task in the field of cluster science. Here we present a three-dimensional (3D) assignment method, combining the energy (1D) and simulated (2D) spectra to assure the assignment of the global minimum structure. Thi...

journal_title：Scientific reports

authors： Liu YR,Huang T,Gai YB,Zhang Y,Feng YJ,Huang W

更新日期：2015-12-03 00:00:00

abstract：:Achieving 180° magnetization reversal with an electric field rather than a current or magnetic field is a fundamental challenge and represents a technological breakthrough towards new memory cell designs. Here we propose a mesoscale morphological engineering approach to accomplishing full 180° magnetization reversals ...

journal_title：Scientific reports

authors： Wang JJ,Hu JM,Ma J,Zhang JX,Chen LQ,Nan CW

更新日期：2014-12-16 00:00:00

abstract：:The oral cavity contains different types of microbial species that colonize human host via extensive cell-to-cell interactions and biofilm formation. Candida albicans-a yeast-like fungus that inhabits mucosal surfaces-is also a significant colonizer of subgingival sites in patients with chronic periodontitis. It is no...

journal_title：Scientific reports

authors： Bartnicka D,Karkowska-Kuleta J,Zawrotniak M,Satała D,Michalik K,Zielinska G,Bochenska O,Kozik A,Ciaston I,Koziel J,Dutton LC,Nobbs AH,Potempa B,Baster Z,Rajfur Z,Potempa J,Rapala-Kozik M

更新日期：2019-03-13 00:00:00

abstract：:The endocannabinoid 2-arachidonoylglycerol (2-AG) functions as a retrograde signaling molecule mediating synaptic transmission and plasticity at both inhibitory and excitatory synapses. However, little is known about whether 2-AG signaling is involved in homeostatic regulation of miniature synaptic events at excitator...

journal_title：Scientific reports

authors： Song Y,Zhang J,Chen C

更新日期：2015-11-06 00:00:00

abstract：:We conducted two online surveys about antibiotics targeted at the Japanese general population in March 2017 and February 2018. In total, 6,982 participants completed the questionnaire. Factors associated with knowledge of antibiotics, knowledge of antimicrobial resistance (AMR) and appropriate behavioural changes were...

journal_title：Scientific reports

authors： Tsuzuki S,Fujitsuka N,Horiuchi K,Ijichi S,Gu Y,Fujitomo Y,Takahashi R,Ohmagari N

更新日期：2020-02-26 00:00:00

abstract：:Genome editing has emerged as a technology with a potential to revolutionize plant breeding. In this study, we report on generating, in less than ten months, Tomelo, a non-transgenic tomato variety resistant to the powdery mildew fungal pathogen using the CRISPR/Cas9 technology. We used whole-genome sequencing to show...

journal_title：Scientific reports

authors： Nekrasov V,Wang C,Win J,Lanz C,Weigel D,Kamoun S

更新日期：2017-03-28 00:00:00

abstract：:Congenital ptosis may be associated with abnormalities of visual development and function, including amblyopia, strabismus and refractive errors. However, the prevalence estimates of these abnormalities vary widely. We performed a systematic review and meta-analysis to estimate the prevalence of amblyopia, strabismus ...

journal_title：Scientific reports

authors： Wang Y,Xu Y,Liu X,Lou L,Ye J

更新日期：2018-05-29 00:00:00

abstract：:A Quality Improvement bundle was implemented with the goal of standardizing the multidisciplinary approach to delivery room management. We used a Pre-Post Quality Improvement initiative with the following aims: (1) Placement of a functioning pulse oximeter by two minutes after birth, (2) Delayed intubation, (3) Normot...

journal_title：Scientific reports

authors： Sauer CW,Boutin MA,Fatayerji AN,Proudfoot JA,Fatayerji NI,Golembeski DJ

更新日期：2016-11-21 00:00:00

abstract：:Abnormal dopaminergic transmission has been implicated as a risk determinant of HIV-1-associated neurocognitive disorders. HIV-1 Tat protein increases synaptic dopamine (DA) levels by directly inhibiting DA transporter (DAT) activity, ultimately leading to dopaminergic neuron damage. Through integrated computational m...

journal_title：Scientific reports

authors： Quizon PM,Sun WL,Yuan Y,Midde NM,Zhan CG,Zhu J

更新日期：2016-12-14 00:00:00

abstract：:To understand the mechanism controlling cultivar differences in the accumulation of ciprofloxacin (CIP) in Chinese flowering cabbage (Brassica parachinensis L.), low-molecular-weight organic acids (LMWOAs) secreted from the roots of high- and low-CIP cultivars (Sijiu and Cutai, respectively) and their effects on the b...

journal_title：Scientific reports

authors： Zhao HM,Xiang L,Wu XL,Jiang YN,Li H,Li YW,Cai QY,Mo CH,Liu JS,Wong MH

更新日期：2017-08-31 00:00:00

abstract：:The human β-defensin-1 (HBD1) is an antimicrobial peptide constitutively expressed by epithelial cells at mucosal surfaces. In addition to its microbicidal properties, the loss of HBD1 expression in several cancers suggests that it may also have an anti-tumor activity. Here, we investigated the link between HBD1 expre...

journal_title：Scientific reports

authors： Bonamy C,Sechet E,Amiot A,Alam A,Mourez M,Fraisse L,Sansonetti PJ,Sperandio B

更新日期：2018-12-21 00:00:00

abstract：:Glycan-protein lateral interactions have gained increased attention as important modulators of receptor function, by regulating surface residence time and endocytosis of membrane glycoproteins. The pathogen-recognition receptor DC-SIGN is highly expressed at the membrane of antigen-presenting dendritic cells, where it...

journal_title：Scientific reports

authors： Te Riet J,Joosten B,Reinieren-Beeren I,Figdor CG,Cambi A

更新日期：2017-07-27 00:00:00

abstract：:Tuberculosis (TB) is a leading infectious cause of death globally. Drug treatment and vaccination, in particular with Bacillus Calmette-Guérin (BCG), remain the main strategies to control TB. With the emergence of drug resistance, it has been proposed that a combination of TB vaccination with pharmacological treatment...

journal_title：Scientific reports

authors： Prabowo SA,Zelmer A,Stockdale L,Ojha U,Smith SG,Seifert K,Fletcher HA

更新日期：2019-03-19 00:00:00

abstract：:Baeyer-Villiger monooxygenases (BVMOs) are able to catalyze regiospecific Baeyer-Villiger oxygenation of a variety of cyclic and linear ketones to generate the corresponding lactones and esters, respectively. However, the enzymes are usually difficult to express in a functional form in microbial cells and are rather u...

journal_title：Scientific reports

authors： Seo JH,Kim HH,Jeon EY,Song YH,Shin CS,Park JB

更新日期：2016-06-17 00:00:00

abstract：:Survivors of Ebola virus infection may become subclinically infected, but whether animal models recapitulate this complication is unclear. Using histology in combination with immunohistochemistry and in situ hybridization in a retrospective review of a guinea pig confirmation-of-virulence study, we demonstrate for the...

journal_title：Scientific reports

authors： Cooper TK,Huzella L,Johnson JC,Rojas O,Yellayi S,Sun MG,Bavari S,Bonilla A,Hart R,Jahrling PB,Kuhn JH,Zeng X

更新日期：2018-01-19 00:00:00

abstract：:Since its recent foundation, phase-coherent caloritronics has sparkled continuous interest giving rise to numerous concrete applications. This research field deals with the coherent manipulation of heat currents in mesoscopic superconducting devices by mastering the Josephson phase difference. Here, we introduce a new...

journal_title：Scientific reports

authors： Guarcello C,Solinas P,Braggio A,Giazotto F

更新日期：2018-08-16 00:00:00

abstract：:Size effect is of great importance in micro forming processes. In this paper, micro cylinder compression was conducted to investigate the deformation behavior of bulk metallic glasses (BMGs) in supercooled liquid region with different deformation variables including sample size, temperature and strain rate. It was fou...

journal_title：Scientific reports

authors： Yao D,Deng L,Zhang M,Wang X,Tang N,Li J

更新日期：2015-01-28 00:00:00

abstract：:Dirt and microorganisms are the major problems in textiles which can generate unpleasant odor during their growth. Here, zinc oxide (ZnO) nanoparticles prepared by sol-gel method were loaded on the cotton fabrics using spin coating technique to enhance their antimicrobial properties and water repellency. The effects o...

journal_title：Scientific reports

authors： Shaban M,Mohamed F,Abdallah S

更新日期：2018-03-02 00:00:00

abstract：:Studies on the phenomenon of magnetoresistance (MR) have produced intriguing and application-oriented outcomes for decades-colossal MR, giant MR and recently discovered extremely large MR of millions of percents in semimetals can be taken as examples. We report here the discovery of novel multiple sign changes versus ...

journal_title：Scientific reports

authors： Pandey A,Mazumdar C,Ranganathan R,Johnston DC

更新日期：2017-02-17 00:00:00

abstract：:Osmosis is the movement of solvent across a permselective membrane induced by a solute-concentration gradient. Now in 'Forward Osmosis' it is empirically observed that the diffusion of the solute is counter to that of the solvent i.e. there is so-called "reverse salt diffusion". However it has been recently suggested,...

journal_title：Scientific reports

authors： Wu JJ,Field RW

更新日期：2019-11-11 00:00:00

abstract：:Memory performance results from plasticity, the ability to change with experience. We show that benefit from practice over a few trials, learning slope, is predictive of long-term recall and hippocampal volume across a broad age range and a long period of time, relates to memory training benefit, and is heritable. Fir...

journal_title：Scientific reports

authors： Walhovd KB,Bråthen ACS,Panizzon MS,Mowinckel AM,Sørensen Ø,de Lange AG,Krogsrud SK,Håberg A,Franz CE,Kremen WS,Fjell AM

更新日期：2020-12-03 00:00:00

abstract：:Two hundred and six strains of avian infectious bronchitis virus (IBV) were isolated from chickens showing signs of disease in southern China during the period from 2013-2015. The nucleotide and amino acid sequences from the isolated field strains were compared to 42 published references. Nucleotide homologies ranged ...

journal_title：Scientific reports

authors： Feng K,Wang F,Xue Y,Zhou Q,Chen F,Bi Y,Xie Q

更新日期：2017-07-26 00:00:00

abstract：:Antibiotic administration, while facilitating clearance of targeted infections, also perturbs commensal microbial communities. Previous studies have all focused on the effects of short term use of antibiotics. Here, we focus on the effects of long term use of antibiotic on gut microbiota and immunity. BALB/c mice rece...

journal_title：Scientific reports

authors： Guo Y,Yang X,Qi Y,Wen S,Liu Y,Tang S,Huang R,Tang L

更新日期：2017-02-21 00:00:00

abstract：:We demonstrate synthesis of Ni/CuOx/Ni nanowires (NWs) by electrochemical deposition on anodized aluminum oxide (AAO) membranes. AAO with pore diameter of ~70 nm and pore length of ~50 μm was used as the template for synthesis of NWs. After deposition of Au as the seed layer, NWs with a structure of Ni/CuOx/Ni were gr...

journal_title：Scientific reports

authors： Park K,Lee JS

更新日期：2016-03-15 00:00:00

abstract：:Sleep has been hypothesised to maintain a close relationship with metabolism. Here we focus on the brain structure that triggers slow-wave sleep, the ventrolateral preoptic nucleus (VLPO), to explore the cellular and molecular signalling pathways recruited by an increase in glucose concentration. We used infrared vide...

journal_title：Scientific reports

authors： Scharbarg E,Daenens M,Lemaître F,Geoffroy H,Guille-Collignon M,Gallopin T,Rancillac A

更新日期：2016-01-12 00:00:00

abstract：:Other than hard bones and shells, it is rare for soft tissues to fossilize, but occasionally they are well-preserved in amber. Here, we focus on both modern and fossilized species of the land snail superfamily Cyclophoroidea. Phylogenetic relationships within the Cyclophoroidea were previously studied using extant spe...

journal_title：Scientific reports

authors： Hirano T,Asato K,Yamamoto S,Takahashi Y,Chiba S

更新日期：2019-11-04 00:00:00