Long-term use of ceftriaxone sodium induced changes in gut microbiota and immune system.

abstract：:Dietary information is lacking in most of small to mid-sized carnivores due to their elusive predatory behaviour and versatile feeding habits. The leopard cat (LPC; Prionailurus bengalensis) and the Asiatic golden cat (AGC; Catopuma temminckii) are two important yet increasingly endangered carnivore species in the tem...

journal_title：Scientific reports

authors： Xiong M,Wang D,Bu H,Shao X,Zhang D,Li S,Wang R,Yao M

更新日期：2017-02-14 00:00:00

abstract：:This research aimed to explore the potential and mechanism of heat modified sawdust combined with Festuca arundinacea for the remediation of Pb-contaminated soil. We determined Pb concentration and biochemical indices in plants and soils, analyzed microbial communities in soil, and studied Pb distribution in subcellul...

journal_title：Scientific reports

authors： Zhang Y,Wang X,Ji H

更新日期：2020-03-13 00:00:00

abstract：:The biodosimetric information is critical for evaluating the human health hazards caused by radon and its progeny. Here, we demonstrated that the formation of phosphorylated histone variant H2AX (γ-H2AX), p53-binding protein 1 (53BP1) and phosphorylated KRAB-associated protein 1 (pKAP-1) foci and their linear tracks i...

journal_title：Scientific reports

authors： Ding D,Zhang Y,Wang J,Wang X,Fan D,He L,Zhang X,Gao Y,Li Q,Chen H

更新日期：2016-12-06 00:00:00

abstract：:Indoor microbial communities play an important role in everyday human health, especially in the intensive care units (ICUs) of hospitals. We used amplicon pyrosequencing to study the ICU microbiome and were able to detect diverse sequences, in comparison to the currently used standard cultivation technique that only d...

journal_title：Scientific reports

authors： Oberauner L,Zachow C,Lackner S,Högenauer C,Smolle KH,Berg G

更新日期：2013-01-01 00:00:00

abstract：:Crystallization is the bottleneck in macromolecular crystallography; even when a protein crystallises, crystal packing often influences ligand-binding and protein-protein interaction interfaces, which are the key points of interest for functional and drug discovery studies. The human hypoxia-inducible factor prolyl hy...

journal_title：Scientific reports

authors： Chowdhury R,Abboud MI,McAllister TE,Banerji B,Bhushan B,Sorensen JL,Kawamura A,Schofield CJ

更新日期：2020-12-15 00:00:00

abstract：:Massive gully land consolidation projects, launched in China's Loess Plateau, aim to restore 2667 [Formula: see text] agricultural lands in total by consolidating 2026 highly eroded gullies. This effort represents a social engineering project where the economic development and livelihood of the farming families are cl...

journal_title：Scientific reports

authors： Yan Q,Kumar P,Wang Y,Zhao Y,Lin H,Ran Q,An Z,Zhou W

更新日期：2020-10-09 00:00:00

abstract：:Light-inducible gene regulation has great potential for remote and noninvasive control of the fate and function of target cells. One method to achieve such control is delivery of heat shock protein (HSP) promoter-driven protein expression vectors and photothermal heaters into the cells, followed by activation by illum...

journal_title：Scientific reports

authors： Nakatsuji H,Kawabata Galbraith K,Kurisu J,Imahori H,Murakami T,Kengaku M

更新日期：2017-07-05 00:00:00

abstract：:We investigate, for the first time, navigation on networks with a Lévy walk strategy such that the step probability scales as pij ~ dij(-α), where dij is the Manhattan distance between nodes i and j, and α is the transport exponent. We find that the optimal transport exponent α(opt) of such a diffusion process is dete...

journal_title：Scientific reports

authors： Weng T,Small M,Zhang J,Hui P

更新日期：2015-11-25 00:00:00

abstract：:Fertilizer application for rice production has increased significantly in southern China to raise yields, but has led to problems with lodging, quality decline and environmental pollution. Therefore, research on fertilizer-saving cultivation technologies for high-yielding rice is necessary. A two-factor experiment was...

journal_title：Scientific reports

authors： Liu Y,Li C,Fang B,Fang Y,Chen K,Zhang Y,Zhang H

更新日期：2019-01-24 00:00:00

abstract：:We demonstrate fluorescent Fe embedded magnetic nanodiamonds by ion implantation and two-step annealing. The diamond characteristics with a highly ordered core and a graphite surface layer are maintained after the implantation process. After the two-step annealing process, a bright red fluorescence associated with nit...

journal_title：Scientific reports

authors： Lin BR,Kunuku S,Chen CH,Chen TY,Hsiao TY,Yu HK,Chang YJ,Liao LC,Niu H,Lee CP

更新日期：2019-02-04 00:00:00

abstract：:The Serra Gaúcha region is the most important temperate fruit-producing area in southern Brazil. Despite mealybugs (Hemiptera: Pseudococcidae) infesting several host plants in the region, there is a lack of information about the composition of species damaging different crops. A survey of mealybug species associated w...

journal_title：Scientific reports

authors： Pacheco da Silva VC,Kaydan MB,Malausa T,Germain JF,Palero F,Botton M

更新日期：2017-11-16 00:00:00

abstract：:The sex-determining gene SRY induces SOX9 expression in the testes of eutherian mammals via two pathways. SRY binds to testis-specific enhancer of Sox9 (TESCO) with SF1 to activate SOX9 transcription. SRY also up-regulates ER71 expression, and ER71 activates Sox9 transcription. After the initiation of testis different...

journal_title：Scientific reports

authors： Otake T,Kuroiwa A

更新日期：2016-09-09 00:00:00

abstract：:p53 is a representative transcription factor that activates multiple target genes. To realize stimulus-dependent specificities, p53 has to recognize targets with structural variety, of which molecular mechanisms are largely unknown. Here, we conducted a series of long-time scale (totally more than 100-ms) coarse-grain...

journal_title：Scientific reports

authors： Terakawa T,Takada S

更新日期：2015-11-24 00:00:00

abstract：:Visfatin/extracellular-nicotinamide-phosphoribosyltranferase-(eNampt) is a multifaceted adipokine enhanced in type-2-diabetes and obesity. Visfatin/eNampt cause in vitro endothelial dysfunction and vascular inflammation, although whether the same effects are achieved in vivo is unknown. Toll-like receptor-4 (TLR4), a ...

journal_title：Scientific reports

authors： Romacho T,Valencia I,Ramos-González M,Vallejo S,López-Esteban M,Lorenzo O,Cannata P,Romero A,San Hipólito-Luengo A,Gómez-Cerezo JF,Peiró C,Sánchez-Ferrer CF

更新日期：2020-03-25 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) patients have poor prognosis and poor response to treatment. This is largely due to PDAC being associated with a dense and active stroma and tumor fibrosis (desmoplasia). Desmoplasia is characterized by excessive degradation and formation of the extracellular matrix (ECM) genera...

journal_title：Scientific reports

authors： Willumsen N,Ali SM,Leitzel K,Drabick JJ,Yee N,Polimera HV,Nagabhairu V,Krecko L,Ali A,Maddukuri A,Moku P,Ali A,Poulose J,Menon H,Pancholy N,Costa L,Karsdal MA,Lipton A

更新日期：2019-12-24 00:00:00

abstract：:Transition metal oxides potentially present higher specific capacities than the current anodes based on carbon, providing an increasing energy density as compared to commercial Li-ion batteries. However, many parameters could influence the performance of the batteries, which depend on the processing of the electrode m...

journal_title：Scientific reports

authors： Prado FD,Andersen HF,Taeño M,Mæhlen JP,Ramírez-Castellanos J,Maestre D,Karazhanov S,Cremades A

更新日期：2020-03-26 00:00:00

abstract：:TiO2/graphene (TiO2-x/GR) composites, which are Ti(3+) self-doped TiO2 nanorods decorated on boron doped graphene sheets, were synthesized via a simple one-step hydrothermal method using low-cost NaBH4 as both a reducing agent and a boron dopant on graphene. The resulting TiO2 nanorods were about 200 nm in length with...

journal_title：Scientific reports

authors： Xing M,Li X,Zhang J

更新日期：2014-06-30 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Hegde A,Suresh S,Mitra R

更新日期：2020-10-06 00:00:00

abstract：:Transient ischemia produces postischemic tingling sensation. Ischemia also produces nerve conduction block that may modulate spinal neural circuits. In the present study, reduced mechanical thresholds for hindpaw-withdrawal reflex were found in mice after transient hindpaw ischemia, which was produced by a high pressu...

journal_title：Scientific reports

authors： Watanabe T,Sasaki M,Komagata S,Tsukano H,Hishida R,Kohno T,Baba H,Shibuki K

更新日期：2015-07-13 00:00:00

abstract：:Activity-regulated cytoskeleton-associated protein (Arc; also known as Arg3.1) is an immediate early gene product that is transcribed in dendritic spines and, to date, has been best characterized as a positive regulator of AMPAR endocytosis during long-term depression (LTD) through interaction with endocytic proteins....

journal_title：Scientific reports

authors： Goo BMSS,Sanstrum BJ,Holden DZY,Yu Y,James NG

更新日期：2018-10-02 00:00:00

abstract：:Telomere DNA ends with a single-stranded 3' overhang. Long 3' overhangs may cause aberrant DNA damage responses and accelerate telomere attrition, which is associated with cancer and aging, respectively. Genetic studies have indicated several important players in preventing 5' end hyper-resection, yet detailed knowled...

journal_title：Scientific reports

authors： Runnberg R,Narayanan S,Cohn M

更新日期：2017-08-18 00:00:00

abstract：:Loss of regenerative capacity plays a critical role in age-related autoimmune hepatitis. Evidence implicates SIRT1 and p66shc in cell senescence, apoptosis, oxidative stress, and proliferation. This study investigated the effect of resveratrol on concanavalin A (Con A)-induced hepatitis in aged mice and the roles of S...

journal_title：Scientific reports

authors： Huang TH,Chen CC,Liu HM,Lee TY,Shieh SH

更新日期：2017-06-02 00:00:00

abstract：:Submillimetre-sized plastic particles (microplastics and nanoplastics) of waste origin in the environment have been repeatedly suggested in recent years to have severe impact on living organisms. While the uptake of these materials has been unequivocally evidenced for animals, so far no adverse effects have been obser...

journal_title：Scientific reports

authors： Hollóczki O,Gehrke S

更新日期：2019-11-05 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Alam MK,Zheng L,Liu R,Papagerakis S,Papagerakis P,Geyer CR

更新日期：2020-09-09 00:00:00

abstract：:This paper describes an origami-inspired self-folding method to form three-dimensional (3D) microstructures of co-cultured cells. After a confluent monolayer of fibroblasts (NIH/3T3 cells) with loaded hepatocytes (HepG2 cells) was cultured onto two-dimensional (2D) microplates, degradation of the alginate sacrificial ...

journal_title：Scientific reports

authors： He Q,Okajima T,Onoe H,Subagyo A,Sueoka K,Kuribayashi-Shigetomi K

更新日期：2018-03-14 00:00:00

abstract：:Zika virus (ZIKV) is a recently re-emerged flavivirus transmitted to humans by mosquito bites but also from mother to fetus and by sexual intercourse. We here show that primary human endometrial stromal cells (HESC) are highly permissive to ZIKV infection and support its in vitro replication. ZIKV envelope expression ...

journal_title：Scientific reports

authors： Pagani I,Ghezzi S,Ulisse A,Rubio A,Turrini F,Garavaglia E,Candiani M,Castilletti C,Ippolito G,Poli G,Broccoli V,Panina-Bordignon P,Vicenzi E

更新日期：2017-03-10 00:00:00

abstract：:In this study we characterise three tandem promoters (PR1-1, PR1-2 and PR1-3) within the PR1 regulatory region of the Escherichia coli kps capsule gene cluster. Transcription from promoter PR1-2 was dependent on the activity of the upstream promoter PR1-1, which activated PR1-2 via transcription coupled DNA supercoili...

journal_title：Scientific reports

authors： Jia J,King JE,Goldrick MC,Aldawood E,Roberts IS

更新日期：2017-12-20 00:00:00

abstract：:The characteristics of aortic valvular outflow jet affect aortopathy in the bicuspid aortic valve (BAV). This study aimed to elucidate the effects of BAV morphology on the aortic valvular outflow jets. Morphotype-specific valve-devising apparatuses were developed to create aortic valve models. A magnetic resonance ima...

journal_title：Scientific reports

authors： Hattori K,Nakama N,Takada J,Nishimura G,Moriwaki R,Kawasaki E,Nagao M,Goto Y,Niinami H,Iwasaki K

更新日期：2021-01-22 00:00:00

abstract：:Sublingual immunization is emerging as an alternative to nasal immunization and induction of mucosal IgA responses. Using Bacillus anthracis edema toxin (EdTx) as an adjuvant, we previously showed that innate responses triggered after sublingual immunization could limit generation of IgA responses. We tested whether c...

journal_title：Scientific reports

authors： Rowe JC,Attia Z,Kim E,Cormet-Boyaka E,Boyaka PN

更新日期：2019-01-24 00:00:00

abstract：:In solid state science, multifunctional materials and especially multiferroics have attracted a great deal of attention, as they open the possibility for next generation spintronic and data storage devices. Interestingly, while many of them host coexisting 3d and 4f elements, the role of the coupling between these two...

journal_title：Scientific reports

authors： Chattopadhyay S,Petit S,Ressouche E,Raymond S,Balédent V,Yahia G,Peng W,Robert J,Lepetit MB,Greenblatt M,Foury-Leylekian P

更新日期：2017-11-06 00:00:00