Spinal mechanisms underlying potentiation of hindpaw responses observed after transient hindpaw ischemia in mice.

abstract：:Episodic ataxia is an autosomal dominant ion channel disorder characterized by episodes of imbalance and incoordination. The disease is genetically heterogeneous and is classified as episodic ataxia type 2 (EA2) when it is caused by a mutation in the CACNA1A gene, encoding the α1A subunit of the P/Q-type voltage-gated...

journal_title：Scientific reports

authors： Sintas C,Carreño O,Fernàndez-Castillo N,Corominas R,Vila-Pueyo M,Toma C,Cuenca-León E,Barroeta I,Roig C,Volpini V,Macaya A,Cormand B

更新日期：2017-05-31 00:00:00

abstract：:(R-)miniCHOP therapy, which delivers approximately half-doses of the (R-)CHOP regimen, has shown efficacy and safety in patients who are more than 80 years old. This study aimed to compare the area under the plasma concentration-time curves (AUCs) of vincristine (VCR), doxorubicin (DXR), and cyclophosphamide (CPA) bet...

journal_title：Scientific reports

authors： Nakagawa J,Takahata T,Hyodo R,Chen Y,Hasui K,Sasaki K,Saito K,Ueno K,Hosoi K,Terui K,Sato A,Niioka T

更新日期：2021-01-12 00:00:00

abstract：:By using silver nanoplatelets with a widely tunable localized surface plasmon resonance (LSPR), and their corresponding local field enhancement, here we show large manipulation of plasmonic enhanced upconversion in NaYF4:Yb(3+)/Er(3+) nanocrystals at the single particle level. In particular, we show that when the plas...

journal_title：Scientific reports

authors： Wang YL,Mohammadi Estakhri N,Johnson A,Li HY,Xu LX,Zhang Z,Alù A,Wang QQ,Shih CK

更新日期：2015-05-15 00:00:00

abstract：:Abnormal dopaminergic transmission has been implicated as a risk determinant of HIV-1-associated neurocognitive disorders. HIV-1 Tat protein increases synaptic dopamine (DA) levels by directly inhibiting DA transporter (DAT) activity, ultimately leading to dopaminergic neuron damage. Through integrated computational m...

journal_title：Scientific reports

authors： Quizon PM,Sun WL,Yuan Y,Midde NM,Zhan CG,Zhu J

更新日期：2016-12-14 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Caldwell DJ,Cronin JA,Wu J,Weaver KE,Ko AL,Rao RPN,Ojemann JG

更新日期：2019-12-27 00:00:00

abstract：:Antimonite [Sb(III)]-oxidizing bacteria can transform the toxic Sb(III) into the less toxic antimonate [Sb(V)]. Recently, the cytoplasmic Sb(III)-oxidase AnoA and the periplasmic arsenite [As(III)] oxidase AioAB were shown to responsible for bacterial Sb(III) oxidation, however, disruption of each gene only partially ...

journal_title：Scientific reports

authors： Li J,Yang B,Shi M,Yuan K,Guo W,Wang Q,Wang G

更新日期：2017-03-02 00:00:00

abstract：:High abundance and widespread distribution of the archaeal phylum Bathyarchaeota in marine environment have been recognized recently, but knowledge about Bathyarchaeota in terrestrial settings and their correlation with environmental parameters is fairly limited. Here we reported the abundance of Bathyarchaeota member...

journal_title：Scientific reports

authors： Xiang X,Wang R,Wang H,Gong L,Man B,Xu Y

更新日期：2017-03-21 00:00:00

abstract：:Recombinant protein and virus-like particle (VLP) production based on the baculovirus expression vector system is fast, flexible, and offers high yields. Independent from the product, a multitude of parameters are screened during process development/optimisation. Early development acceleration is a key requirement for...

journal_title：Scientific reports

authors： Strobl F,Ghorbanpour SM,Palmberger D,Striedner G

更新日期：2020-01-23 00:00:00

abstract：:The experimental study deals with the investigation of the effect of diverse crystallinity of imidazolium ionic-liquid-based SPE on conductivity and current fluctuations. The experimental study was carried out on samples consisting of [EMIM][TFSI] as ionic liquid, PVDF as a polymer matrix and NMP as a solvent. After t...

journal_title：Scientific reports

authors： Sedlak P,Gajdos A,Macku R,Majzner J,Holcman V,Sedlakova V,Kubersky P

更新日期：2020-12-03 00:00:00

abstract：:The bronchoscopy, though usually safe, is occasionally associated with complications, such as pneumonia. However, the use of prophylactic antibiotics is not recommended by the guidelines of the British Thoracic Society. Thus far there are few reports of the risk factors for post-bronchoscopy pneumonia; the purpose of ...

journal_title：Scientific reports

authors： Sato Y,Murata K,Yamamoto M,Ishiwata T,Kitazono-Saitoh M,Wada A,Takamori M

更新日期：2020-11-17 00:00:00

abstract：:A clinical study was designed to record a wide range of physiological values from patients undergoing haemodialysis treatment in the Renal Unit of the Churchill Hospital in Oxford. Video was recorded for a total of 84 dialysis sessions from 40 patients during the course of 1 year, comprising an overall video recording...

journal_title：Scientific reports

authors： Villarroel M,Jorge J,Meredith D,Sutherland S,Pugh C,Tarassenko L

更新日期：2020-10-28 00:00:00

abstract：:The aim of this study was to fabricate a novel polymer-free everolimus-eluting stent with nanostructure using a femtosecond laser (FSL). The stent were coated with everolimus (EVL) using FSL and electrospinning processes. The surface was rendered hydrophobic, which negatively affected both platelet adhesion (82.1%) an...

journal_title：Scientific reports

authors： Bae IH,Jeong MH,Lim KS,Park DS,Shim JW,Park JK,Oh KH,Jin MR,Sim DS

更新日期：2018-05-09 00:00:00

abstract：:Circular Dichroism data are often decomposed into their constituent spectra to quantify the secondary structure of peptides or proteins but the estimation of the secondary structure content fails when light scattering leads to spectral distortion. If peptide-induced liposome self-association occurs, subtracting contro...

journal_title：Scientific reports

authors： Vermeer LS,Marquette A,Schoup M,Fenard D,Galy A,Bechinger B

更新日期：2016-12-22 00:00:00

abstract：:The monitoring and early detection of abnormalities or variations in the cardiac cycle functionality are very critical practices and have significant impact on the prevention of heart diseases and their associated complications. Currently, in the field of biomedical engineering, there is a growing need for devices cap...

journal_title：Scientific reports

authors： Ahmad MA

更新日期：2016-11-17 00:00:00

abstract：:The Antarctic silverfish (Pleuragramma antarctica) is a critically important forage species with a circumpolar distribution and is unique among other notothenioid species for its wholly pelagic life cycle. Previous studies have provided mixed evidence of population structure over regional and circumpolar scales. The a...

journal_title：Scientific reports

authors： Caccavo JA,Papetti C,Wetjen M,Knust R,Ashford JR,Zane L

更新日期：2018-12-14 00:00:00

abstract：:We investigated the extent to which pre-pregnancy obesity mediates the association between maternal place of birth and severe pre-eclampsia in the PreCARE cohort of pregnant women in Paris (n = 9,579). Adjusted path analysis logistic regression models were used to assess the role of pre-pregnancy obesity as a mediator...

journal_title：Scientific reports

authors： Siddiqui A,Deneux-Tharaux C,Luton D,Schmitz T,Mandelbrot L,Estellat C,Howell EA,Khoshnood B,Bertille N,Azria E

更新日期：2020-03-23 00:00:00

abstract：:Mechanistic disease progression studies using animal models require objective and quantifiable assessment of tissue pathology. Currently quantification relies heavily on staining methods which can be expensive, labor/time-intensive, inconsistent across laboratories and batch, and produce uneven staining that is prone ...

journal_title：Scientific reports

authors： Ternes L,Huang G,Lanciault C,Thibault G,Riggers R,Gray JW,Muschler J,Chang YH

更新日期：2020-12-01 00:00:00

abstract：:In chickens, the sensory organs for taste are the taste buds in the oral cavity, of which there are ~240-360 in total number as estimated by scanning electron microscopy (SEM). There is not an easy way to visualize all taste buds in chickens. Here, we report a highly efficient method for labeling chicken taste buds in...

journal_title：Scientific reports

authors： Rajapaksha P,Wang Z,Venkatesan N,Tehrani KF,Payne J,Swetenburg RL,Kawabata F,Tabata S,Mortensen LJ,Stice SL,Beckstead R,Liu HX

更新日期：2016-11-17 00:00:00

abstract：:We report on measurements of the switching current distributions on two-dimensional superconducting NbTiN strips that are 5 nm thick and 80 nm wide. We observe that the width of the switching current distributions has a non-monotonous temperature dependence, where it is constant at the lowest temperatures up to about ...

journal_title：Scientific reports

authors： Ejrnaes M,Salvoni D,Parlato L,Massarotti D,Caruso R,Tafuri F,Yang XY,You LX,Wang Z,Pepe GP,Cristiano R

更新日期：2019-05-29 00:00:00

abstract：:Parental age is increasing rapidly in many countries. Analysis of this potentially important influence on offspring well-being is hampered by strong secular trends and socioeconomic patterning and by a shortage of follow-up data for adult offspring. We used Swedish national data on up to 3,653,938 offspring to conside...

journal_title：Scientific reports

authors： Carslake D,Tynelius P,van den Berg G,Davey Smith G,Rasmussen F

更新日期：2017-03-27 00:00:00

abstract：:Electrolyte concentration in sweat depends on environmental context and physical condition but also on the pathophysiological status. Sweat analyzers may be therefore the future way for biological survey although how sweat electrolyte composition can reflect plasma composition remains unclear. We recruited 10 healthy ...

journal_title：Scientific reports

authors： Vairo D,Bruzzese L,Marlinge M,Fuster L,Adjriou N,Kipson N,Brunet P,Cautela J,Jammes Y,Mottola G,Burtey S,Ruf J,Guieu R,Fenouillet E

更新日期：2017-09-18 00:00:00

abstract：:Saponins represent a promising class of vaccine adjuvant. Together with the TLR4-ligand MPL, QS-21 is part of the Adjuvant System AS01, a key component of the malaria and zoster candidate vaccines that display demonstrated clinical efficacy. However, the mechanism of action of QS-21 in this liposomal formulation is po...

journal_title：Scientific reports

authors： Detienne S,Welsby I,Collignon C,Wouters S,Coccia M,Delhaye S,Van Maele L,Thomas S,Swertvaegher M,Detavernier A,Elouahabi A,Goriely S,Didierlaurent AM

更新日期：2016-12-20 00:00:00

abstract：:Amyloids are cross-β-sheet fibrillar aggregates, associated with various human diseases and native functions such as protein/peptide hormone storage inside secretory granules of neuroendocrine cells. In the current study, using amyloid detecting agents, we show that growth hormone (GH) could be stored as amyloid in th...

journal_title：Scientific reports

authors： Jacob RS,Das S,Ghosh S,Anoop A,Jha NN,Khan T,Singru P,Kumar A,Maji SK

更新日期：2016-03-23 00:00:00

abstract：:Transcription factors (TFs) binding to specific DNA sequences or motifs, are elementary to the regulation of transcription. The gene is regulated by a combination of TFs in close proximity. Analysis of co-TFs is an important problem in understanding the mechanism of transcriptional regulation. Recently, ChIP-seq in ma...

journal_title：Scientific reports

authors： Pan G,Tang J,Guo F

更新日期：2017-02-27 00:00:00

abstract：:Accurate measurements of autonomic nerve regulation in heart failure (HF) were unresolved. The discriminating performance of deceleration and acceleration capacities of heart rate in HF was evaluated in 130 HF patients and 212 controls. Acceleration capacity and deceleration capacity were independent risk factors for ...

journal_title：Scientific reports

authors： Hu W,Jin X,Zhang P,Yu Q,Yin G,Lu Y,Xiao H,Chen Y,Zhang D

更新日期：2016-03-23 00:00:00

abstract：:Tomato spotted wilt virus is a wide-spread plant disease in the world. It can threaten thousands of plants with a persistent and propagative manner. Early disease detection is expected to be able to control the disease spread, to facilitate management practice, and further to guarantee accompanying economic benefits. ...

journal_title：Scientific reports

authors： Wang D,Vinson R,Holmes M,Seibel G,Bechar A,Nof S,Tao Y

更新日期：2019-03-13 00:00:00

abstract：:Nowadays, increasing awareness of environment and fossil fuels protection stimulates intensive research on clean and renewable sources of energy. Production of hydrogen from water through solar-driven splitting reactions is one of the most promising approaches in the field of photoelectrochemistry (PEC). In this work ...

journal_title：Scientific reports

authors： Zare M,Solaymani S,Shafiekhani A,Kulesza S,Ţălu Ş,Bramowicz M

更新日期：2018-07-18 00:00:00

abstract：:Quantum key distribution involving decoy-states is a significant application of quantum information. By using three-intensity decoy-states of single-photon-added coherent sources, we propose a practically realizable scheme on quantum key distribution which approaches very closely the ideal asymptotic case of an infini...

journal_title：Scientific reports

authors： Wang D,Li M,Guo GC,Wang Q

更新日期：2015-10-14 00:00:00

abstract：:Recent studies have shown that the representation of an item in visual working memory (VWM) can bias the deployment of attention to stimuli in the visual scene possessing the same features. When multiple item representations are simultaneously held in VWM, whether these representations, especially those held in a non-...

journal_title：Scientific reports

authors： Zhang B,Liu S,Doro M,Galfano G

更新日期：2018-09-17 00:00:00

abstract：:Interleukin-27 (IL-27) is an important cytokine in inflammatory diseases, including coronary artery disease (CAD). To explore the precise role of IL-27 in CAD, we investigated the genetic association between IL27 and CAD in the GeneID Chinese Han population. A two-stage case control association analysis was performed ...

journal_title：Scientific reports

authors： Fan Q,Nie S,Li S,Liao Y,Zhang H,Zha L,Wang F,Tang T,Xia N,Xu C,Wang P,Xie T,Xie J,Lu Q,Li Q,Qian J,Li B,Wu G,Wu Y,Yang Y,Wang QK,Tu X,Cheng X

更新日期：2016-05-12 00:00:00