Abstract:
:Submillimetre-sized plastic particles (microplastics and nanoplastics) of waste origin in the environment have been repeatedly suggested in recent years to have severe impact on living organisms. While the uptake of these materials has been unequivocally evidenced for animals, so far no adverse effects have been observed in the corresponding animal experiments. In this study, we show that nanoplastics are prone to interact with proteins, and this interaction fundamentally changes the functionally crucial secondary structure of these biomolecules, and thereby denaturates them. These results show, for the first time, that the interplay between plastic waste and biological matter can induce significant cellular and thereby ecological damages. Observing these remarkable microscopic level changes highlights the urgent need to extend investigating the effects of these materials through further modelling and molecular biological methods.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Hollóczki O,Gehrke Sdoi
10.1038/s41598-019-52495-wsubject
Has Abstractpub_date
2019-11-05 00:00:00pages
16013issue
1issn
2045-2322pii
10.1038/s41598-019-52495-wjournal_volume
9pub_type
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journal_title:Scientific reports
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 已发布勘误
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pub_type: 杂志文章
doi:10.1038/s41598-019-42669-x
更新日期:2019-04-16 00:00:00
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pub_type: 杂志文章
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journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08957-0
更新日期:2017-08-23 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1038/s41598-018-26323-6
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journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51715-7
更新日期:2019-10-31 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
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pub_type: 已发布勘误
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更新日期:2018-02-19 00:00:00
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journal_title:Scientific reports
pub_type: 杂志文章
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更新日期:2016-06-20 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2017-06-16 00:00:00
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pub_type: 杂志文章
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journal_title:Scientific reports
pub_type: 杂志文章
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更新日期:2018-05-08 00:00:00
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journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27290-8
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2016-04-07 00:00:00