microRNA Expression in Ethnic Specific Early Stage Breast Cancer: an Integration and Comparative Analysis.

abstract：:We characterised wool traits, and skin gene expression profiles of fine wool Super Merino (SM) and coarse wool Small Tail Han (STH) sheep. SM sheep had a significantly higher total density of wool follicles, heavier fleeces, finer fibre diameter, and increased crimp frequency, staple length and wool grease (lanolin) p...

journal_title：Scientific reports

authors： Zhang L,Sun F,Jin H,Dalrymple BP,Cao Y,Wei T,Vuocolo T,Zhang M,Piao Q,Ingham AB

更新日期：2017-10-30 00:00:00

abstract：:The consumption of bovine milk and meat is considered a risk factor for colon- and breast cancer formation, and milk consumption has also been implicated in an increased risk for developing Multiple Sclerosis (MS). A number of highly related virus-like DNAs have been recently isolated from bovine milk and sera and fro...

journal_title：Scientific reports

authors： Eilebrecht S,Hotz-Wagenblatt A,Sarachaga V,Burk A,Falida K,Chakraborty D,Nikitina E,Tessmer C,Whitley C,Sauerland C,Gunst K,Grewe I,Bund T

更新日期：2018-02-12 00:00:00

abstract：:Uveitis, the pathologic condition of inflammation of the uvea, frequently leads to severe vision loss and blindness. S100A8 is a calcium-binding protein which mainly expresses in granulocytes and monocytes and plays a prominent role in the regulation of inflammatory processes and immune response. Here, we determined t...

journal_title：Scientific reports

authors： Wang Y,Zhang Z,Zhang L,Li X,Lu R,Xu P,Zhang X,Dai M,Dai X,Qu J,Lu F,Chi Z

更新日期：2016-10-27 00:00:00

abstract：:Measurement-based quantum computing is one of the most promising quantum computing models. Although various universal resource states have been proposed so far, it was open whether only two Pauli bases are enough for both of universal measurement-based quantum computing and its verification. In this paper, we construc...

journal_title：Scientific reports

authors： Takeuchi Y,Morimae T,Hayashi M

更新日期：2019-09-19 00:00:00

abstract：:Increasing population has posed insurmountable challenges to agriculture in the provision of future food security, particularly in the Middle East and North Africa (MENA) region where biophysical conditions are not well-suited for agriculture. Iran, as a major agricultural country in the MENA region, has long been in ...

journal_title：Scientific reports

authors： Mesgaran MB,Madani K,Hashemi H,Azadi P

更新日期：2017-08-09 00:00:00

abstract：:There has been much interest in understanding collective dynamics in networks of brain regions due to their role in behavior and cognitive function. Here we show that a simple, homogeneous system of densely connected oscillators, representing the aggregate activity of local brain regions, can exhibit a rich variety of...

journal_title：Scientific reports

authors： Singh R,Menon SN,Sinha S

更新日期：2016-02-26 00:00:00

abstract：:The melting of glaciers and ice sheets is nowadays considered a symbol of climate change. Many complex mechanisms are involved in the melting of ice, and, among these processes, surface darkening due to organic material on bare ice has recently received attention from the scientific community. The presence of microbes...

journal_title：Scientific reports

authors： Di Mauro B,Garzonio R,Baccolo G,Franzetti A,Pittino F,Leoni B,Remias D,Colombo R,Rossini M

更新日期：2020-03-16 00:00:00

abstract：:Vascular leakage is a life-threatening complication of dengue virus (DENV) infection. Previously, association between "paracellular" endothelial hyperpermeability and plasma leakage had been extensively investigated. However, whether "transcellular" endothelial leakage is involved in dengue hemorrhagic fever (DHF) and...

journal_title：Scientific reports

authors： Chanthick C,Kanlaya R,Kiatbumrung R,Pattanakitsakul SN,Thongboonkerd V

更新日期：2016-08-22 00:00:00

abstract：:Ovule-derived haploid culture is an effective and important method for genetic study and plant breeding. Gerbera hybrida is a highly heterozygous species, and the lack of homozygous lines presents a challenge for molecular genetic research. Therefore, we performed haploid induction through unpollinated ovule culture a...

journal_title：Scientific reports

authors： Li F,Cheng Y,Zhao X,Yu R,Li H,Wang L,Li S,Shan Q

更新日期：2020-02-03 00:00:00

abstract：:Sunflower see/ds (Helianthus annuus L.) were roasted in an electric forced air oven for 15, 30, 45, and 60 min at 125, 135 and 145 °C. The effect of temperature and time on the flavor profile of the samples were evaluated by headspace solid-phase microextraction coupled with gas chromatography-mass spectroscopy (HS-SP...

journal_title：Scientific reports

authors： Guo S,Na Jom K,Ge Y

更新日期：2019-08-05 00:00:00

abstract：:The Next-Generation Sequencing (NGS) platforms provide a major approach to obtaining millions of short reads from samples. NGS has been used in a wide range of analyses, such as for determining genome sequences, analyzing evolutionary processes, identifying gene expression and resolving metagenomic analyses. Usually, ...

journal_title：Scientific reports

authors： Gaia ASC,de Sá PHCG,de Oliveira MS,Veras AAO

更新日期：2019-08-12 00:00:00

abstract：:Antibiotic administration, while facilitating clearance of targeted infections, also perturbs commensal microbial communities. Previous studies have all focused on the effects of short term use of antibiotics. Here, we focus on the effects of long term use of antibiotic on gut microbiota and immunity. BALB/c mice rece...

journal_title：Scientific reports

authors： Guo Y,Yang X,Qi Y,Wen S,Liu Y,Tang S,Huang R,Tang L

更新日期：2017-02-21 00:00:00

abstract：:Channelrhodopsins are light-gated ion channels of green algae used for the precise temporal and spatial control of transmembrane ion fluxes. The channelrhodopsin Chrimson from Chlamydomonas noctigama allows unprecedented deep tissue penetration due to peak absorption at 590 nm. We demonstrate by electrophysiological r...

journal_title：Scientific reports

authors： Vierock J,Grimm C,Nitzan N,Hegemann P

更新日期：2017-08-30 00:00:00

abstract：:We report the transient memory device by means of a water soluble SSG (solid sodium with glycerine) paper. This material has a hydroscopic property hence it can be soluble in water. In terms of physical security of memory devices, prompt abrogation of a memory device which stored a large number of data is crucial when...

journal_title：Scientific reports

authors： Bae H,Lee BH,Lee D,Seol ML,Kim D,Han JW,Kim CK,Jeon SB,Ahn D,Park SJ,Park JY,Choi YK

更新日期：2016-12-05 00:00:00

abstract：:MicroRNAs (miRNAs) have been considered to be potent biomarkers for early disease diagnosis and for cancer therapy. The rapid and selective detection of miRNAs without reverse transcription and labelling is highly desired. Herein, we report a simple and label-free miRNA detection method that is based on the Duplex-Spe...

journal_title：Scientific reports

authors： Yan L,Yan Y,Pei L,Wei W,Zhao J

更新日期：2014-12-10 00:00:00

abstract：:An efficient [4 + 1] annulation between α-bromooximes and sulfur ylides via in situ generation of nitrosoalkenes under mild basic reaction conditions has been developed, providing an expeditious and scalable approach to synthesize biologically interesting isoxazoline derivatives with good to excellent yields. ...

journal_title：Scientific reports

authors： Hua TB,Liu CX,Hu WM,Wang L,Yang QQ

更新日期：2021-01-22 00:00:00

abstract：:We aimed to assess the ankle-brachial index (ABI) in patients with Graves' disease. In the cross-sectional assessments, 81 patients with drug-naïve Graves' disease and 235 with euthyroidism were enrolled. ABI and vascular cell adhesion molecule-1 (VCAM-1) levels were assessed. In the prospective follow-up, 32 patients...

journal_title：Scientific reports

authors： Li YH,Lee IT

更新日期：2020-10-13 00:00:00

abstract：:E. coli is the main causative agent of mastitis in dairy cows, but the mechanism of molecular regulation underlying the occurrence and development of mastitis has not yet been fully elucidated. In this study, an E. coli-induced mastitis model was created and RNASeq technology was used to measure the miRNA expression p...

journal_title：Scientific reports

authors： Luoreng ZM,Wang XP,Mei CG,Zan LS

更新日期：2018-08-23 00:00:00

abstract：:Recent advances in next-generation sequencing technologies have paved the path for a considerable amount of sequencing data at a relatively low cost. This has revolutionized the genomics and transcriptomics studies. However, different challenges are now created in handling such data with available bioinformatics platf...

journal_title：Scientific reports

authors： Naranpanawa DNU,Chandrasekara CHWMRB,Bandaranayake PCG,Bandaranayake AU

更新日期：2020-10-26 00:00:00

abstract：:The introduction of antiretroviral drugs (ARVd) changed the prognosis of HIV infection from a deadly disease to a chronic disease. However, even with undetectable viral loads, patients still develop a wide range of pathologies, including cerebrovascular complications and stroke. It is hypothesized that toxic side effe...

journal_title：Scientific reports

authors： Bertrand L,Dygert L,Toborek M

更新日期：2016-12-23 00:00:00

abstract：:Transgenic rice producing insecticidal proteins from Bacillus thuringiensis (Bt) could help protect the plants from damage by lepidopteran pests. However, one concern is the potential of Bt rice to harm non-target natural enemies, which play a vital role in pest control. In the present study, the potential effects of ...

journal_title：Scientific reports

authors： Tian JC,Romeis J,Liu K,Zhang FC,Zheng XS,Xu HX,Chen GH,He XC,Lu ZX

更新日期：2017-08-10 00:00:00

abstract：:The exact roles of acid-sensing ion channels (ASICs) in synaptic plasticity remain elusive. Here, we address the contribution of ASIC1a to five forms of synaptic plasticity in the mouse hippocampus using an in vitro multi-electrode array recording system. We found that genetic deletion or pharmacological blockade of A...

journal_title：Scientific reports

authors： Liu MG,Li HS,Li WG,Wu YJ,Deng SN,Huang C,Maximyuk O,Sukach V,Krishtal O,Zhu MX,Xu TL

更新日期：2016-03-21 00:00:00

abstract：:The general disease burden associated with the restrictive spirometric pattern (RSP) is substantial. However, the impact of RSP by its severity on general health problems and quality of life has not been well elucidated. This study aimed to analyse nutrition, physical activity, and quality of life in subjects who part...

journal_title：Scientific reports

authors： Chung SJ,Kim HI,Yang B,Kim T,Sim YS,Kang HK,Kim SH,Yoon HJ,Choi H,Lee H

更新日期：2020-11-12 00:00:00

abstract：:The human cytomegalovirus developed distinct evasion mechanisms from the cellular antiviral response involving vMIA, a virally-encoded protein that is not only able to prevent cellular apoptosis but also to inhibit signalling downstream from mitochondrial MAVS. vMIA has been shown to localize at mitochondria and to tr...

journal_title：Scientific reports

authors： Magalhães AC,Ferreira AR,Gomes S,Vieira M,Gouveia A,Valença I,Islinger M,Nascimento R,Schrader M,Kagan JC,Ribeiro D

更新日期：2016-05-16 00:00:00

abstract：:Visceral adiposity is a risk factor for cardiovascular disorders, type 2 diabetes mellitus (T2D) and associated metabolic diseases. Sub-cutaneous fat is believed to be intrinsically different from visceral fat. To understand molecular mechanisms involved in metabolic advantages of fat transplantation, we studied a rat...

journal_title：Scientific reports

authors： Satoor SN,Puranik AS,Kumar S,Williams MD,Ghale M,Rahalkar A,Karandikar MS,Shouche Y,Patole M,Bhonde R,Yajnik CS,Hardikar AA

更新日期：2011-01-01 00:00:00

abstract：:High-resolution microscopy is a valuable tool for studying cellular processes, such as signalling, membrane trafficking, or cytoskeleton remodelling. Several techniques of inclined illumination microscopy allow imaging at a near single molecular level; however, the application of these methods to plant cells is limite...

journal_title：Scientific reports

authors： Kozgunova E,Goshima G

更新日期：2019-10-23 00:00:00

abstract：:Influenza viruses are among the most common pathogens that threaten the health of humans and animals worldwide. Various anti-viral therapeutic agents are currently used for treatment and prophylaxis of influenza virus, but the targets of these drugs are easily mutated and result in resistance. Therefore, medications t...

journal_title：Scientific reports

authors： Pang B,Cheung NN,Zhang W,Dai J,Kao RY,Zhang H,Hao Q

更新日期：2016-07-11 00:00:00

abstract：:Thermo-elasticity couples the deformation of an elastic (solid) body to its temperature and vice-versa. It is a solid-like property. Highlighting such property in liquids is a paradigm shift: it requires long-range collective interactions that are not considered in current liquid descriptions. The present microthermal...

journal_title：Scientific reports

authors： Kume E,Baroni P,Noirez L

更新日期：2020-08-07 00:00:00

abstract：:The human pathogen Legionella pneumophila delivers a large array of the effector proteins into host cells using the Dot/Icm type IVB secretion system. Among the proteins composing the Dot/Icm system, an inner membrane protein DotI is known to be crucial for the secretion function but its structure and role in type IV ...

journal_title：Scientific reports

authors： Kuroda T,Kubori T,Thanh Bui X,Hyakutake A,Uchida Y,Imada K,Nagai H

更新日期：2015-06-03 00:00:00

abstract：:Viruses use a strategy of high mutational rates to adapt to environmental and therapeutic pressures, circumventing the deleterious effects of random single-point mutations by coevolved compensatory mutations, which restore protein fold, function or interactions damaged by initial ones. This mechanism has been identifi...

journal_title：Scientific reports

authors： Khwaja A,Galilee M,Marx A,Alian A

更新日期：2016-04-22 00:00:00