Delivery Room Quality Improvement Project Improved Compliance with Best Practices for a Community NICU.

abstract：:Biological networks play a key role in determining biological function and therefore, an understanding of their structure and dynamics is of central interest in systems biology. In Boolean models of such networks, the status of each molecule is either "on" or "off" and along with the molecules interact with each other...

journal_title：Scientific reports

authors： Chen H,Wang G,Simha R,Du C,Zeng C

更新日期：2016-01-29 00:00:00

abstract：:The auditory steady-state response (ASSR) has been used to detect auditory processing deficits in patients with psychiatric disorders. However, the methodology of ASSR recording from the brain surface has not been standardized in preclinical studies, limiting its use as a translational biomarker. The sites of maximal ...

journal_title：Scientific reports

authors： Kozono N,Honda S,Tada M,Kirihara K,Zhao Z,Jinde S,Uka T,Yamada H,Matsumoto M,Kasai K,Mihara T

更新日期：2019-06-11 00:00:00

abstract：:Human respiratory syncytial virus (RSV) A ON1 genotype, first detected in 2010 in Ontario, Canada, has been documented in 21 countries to date. This study investigated persistence and transmission dynamics of ON1 by grouping 406 randomly selected RSV-positive specimens submitted to Public Health Ontario from August 20...

journal_title：Scientific reports

authors： Duvvuri VR,Granados A,Rosenfeld P,Bahl J,Eshaghi A,Gubbay JB

更新日期：2015-09-30 00:00:00

abstract：:Metabolic syndrome (MS) could be associated with liver function. Our study aimed to investigate the association between liver function and MS in a large cohort of Chinese men and women. We enrolled 32,768 ostensibly healthy participants. The associations between liver function and MS of both genders were analyzed sepa...

journal_title：Scientific reports

authors： Wang S,Zhang J,Zhu L,Song L,Meng Z,Jia Q,Li X,Liu N,Hu T,Zhou P,Zhang Q,Liu L,Song K,Jia Q

更新日期：2017-03-20 00:00:00

abstract：:X-linked severe combined immunodeficiency (SCID-X1) caused by mutations in interleukin 2 receptor gamma (IL2RG) gene threatens the survival of affected boys during the first year of life unless hematopoietic stem cell transplantation is provided. Although viral vector-mediated gene therapy has been successfully perfor...

journal_title：Scientific reports

authors： Matsubara Y,Chiba T,Kashimada K,Morio T,Takada S,Mizutani S,Asahara H

更新日期：2014-05-23 00:00:00

abstract：:The L-iduronic acid (IdoA) residue is a critically important structural component in heparan sulphate polysaccharide for the biological functions. The pyranose ring of IdoA is present in (1)C4-chair, (2)SO-skew boat, and less frequently, in (4)C1-chair conformations. Here, we analyzed the conformation of IdoA residue ...

journal_title：Scientific reports

authors： Hsieh PH,Thieker DF,Guerrini M,Woods RJ,Liu J

更新日期：2016-07-14 00:00:00

abstract：:Horseradish peroxidase (HRP) mediates efficient conversion of many phenolic contaminants and thus has potential applications for pollution control. Such potentially important applications suffer however from the fact that the enzyme becomes quickly inactivated during phenol oxidation and polymerization. The work here ...

journal_title：Scientific reports

authors： Mao L,Luo S,Huang Q,Lu J

更新日期：2013-11-04 00:00:00

abstract：:The airways of individuals with cystic fibrosis (CF) are abundantly colonised by Staphylococcus aureus and Pseudomonas aeruginosa. Co-infecting hypoxic regions of static mucus within CF airways, together with decreases in pulmonary function, mucus plugging and oxygen consumption by host neutrophils gives rise to regio...

journal_title：Scientific reports

authors： Pallett R,Leslie LJ,Lambert PA,Milic I,Devitt A,Marshall LJ

更新日期：2019-05-01 00:00:00

abstract：:Transcriptionally silent heterochromatin is associated with repetitive DNA. It is poorly understood whether and how heterochromatin differs between different organisms and whether its structure can be remodelled in response to environmental signals. Here, we address this question by analysing the chromatin state assoc...

journal_title：Scientific reports

authors： Freire-Benéitez V,Price RJ,Tarrant D,Berman J,Buscaino A

更新日期：2016-03-14 00:00:00

abstract：:We present a comparative study of plasmonic antennas fabricated by electron beam lithography and direct focused ion beam milling. We have investigated optical and structural properties and chemical composition of gold disc-shaped plasmonic antennas on a silicon nitride membrane fabricated by both methods to identify t...

journal_title：Scientific reports

authors： Horák M,Bukvišová K,Švarc V,Jaskowiec J,Křápek V,Šikola T

更新日期：2018-06-25 00:00:00

abstract：:Bile acid (BA) signatures are altered in many disease states. BA metabolism is an important microbial function to assist gut colonization and persistence, as well as microbial survival during gastro intestinal (GI) transit and it is an important criteria for potential probiotic bacteria. Microbes that express bile sal...

journal_title：Scientific reports

authors： Prete R,Long SL,Gallardo AL,Gahan CG,Corsetti A,Joyce SA

更新日期：2020-01-24 00:00:00

abstract：:The 28,000-year-old remains of a woolly mammoth, named 'Yuka', were found in Siberian permafrost. Here we recovered the less-damaged nucleus-like structures from the remains and visualised their dynamics in living mouse oocytes after nuclear transfer. Proteomic analyses demonstrated the presence of nuclear components ...

journal_title：Scientific reports

authors： Yamagata K,Nagai K,Miyamoto H,Anzai M,Kato H,Miyamoto K,Kurosaka S,Azuma R,Kolodeznikov II,Protopopov AV,Plotnikov VV,Kobayashi H,Kawahara-Miki R,Kono T,Uchida M,Shibata Y,Handa T,Kimura H,Hosoi Y,Mitani T,Matsumo

更新日期：2019-03-11 00:00:00

abstract：:There is a global concern about the effects of climate change driven shifts in species phenology on crop pests. Using geographically and temporally extensive data set of moth trap catches and temperatures across the cotton growing states of India, we predicted the phenology of cotton pink bollworm Pectinophora gossypi...

journal_title：Scientific reports

authors： Fand BB,Nagrare VS,Bal SK,Naik VCB,Naikwadi BV,Mahule DJ,Gokte-Narkhedkar N,Waghmare VN

更新日期：2021-01-11 00:00:00

abstract：:Plant defensins (PDFs) are cysteine-rich peptides that have a range of biological functions, including defence against fungal pathogens. However, little is known about their role in defence against bacteria. In this study, we showed that the protein encoded by ARABIDOPSIS THALIANA PLANT DEFENSIN TYPE 1.1 (AtPDF1.1) is...

journal_title：Scientific reports

authors： Hsiao PY,Cheng CP,Koh KW,Chan MT

更新日期：2017-08-23 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Guo S,Pridham KJ,Virbasius CM,He B,Zhang L,Varmark H,Green MR,Sheng Z

更新日期：2019-06-10 00:00:00

abstract：:Episodic memories are long lasting and full of detail, yet imperfect and malleable. We quantitatively evaluated recollection of short audiovisual segments from movies as a proxy to real-life memory formation in 161 subjects at 15 minutes up to a year after encoding. Memories were reproducible within and across individ...

journal_title：Scientific reports

authors： Tang H,Singer J,Ison MJ,Pivazyan G,Romaine M,Frias R,Meller E,Boulin A,Carroll J,Perron V,Dowcett S,Arellano M,Kreiman G

更新日期：2016-09-30 00:00:00

abstract：:A correction has been published and is appended to both the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Crollen V,Albouy G,Lepore F,Collignon O

更新日期：2017-12-04 00:00:00

abstract：:Methods to repair bone defects arising from trauma, resection, or disease, continue to be sought after. Cyclic mechanical loading is well established to influence bone (re)modelling activity, in which bone formation and resorption are correlated to micro-scale strain. Based on this, the application of mechanical stimu...

journal_title：Scientific reports

authors： Malhotra A,Walle M,Paul GR,Kuhn GA,Müller R

更新日期：2021-01-21 00:00:00

abstract：:The G protein-coupled pituitary adenylate cyclase-activating polypeptide receptor (PAC1R) is a potential therapeutic target for endocrine, metabolic and stress-related disorders. However, many questions regarding the protein structure and dynamics of PAC1R remain largely unanswered. Using microsecond-long simulations,...

journal_title：Scientific reports

authors： Liao C,Zhao X,Brewer M,May V,Li J

更新日期：2017-07-14 00:00:00

abstract：:The aim of the study was to investigate the role of endogenous sulfur dioxide (SO2)/ aspartate aminotransferase 1 (AAT1) pathway in stretch-induced excessive collagen expression and its mechanism. The mechanical stretch downregulated SO2/AAT1 pathway and increased collagen I and III protein expression. Importantly, AA...

journal_title：Scientific reports

authors： Liu J,Yu W,Liu Y,Chen S,Huang Y,Li X,Liu C,Zhang Y,Li Z,Du J,Tang C,Du J,Jin H

更新日期：2016-02-16 00:00:00

abstract：:Chinese liquor aroma components were characterized during the aging process using gas chromatography (GC). Principal component and cluster analysis (PCA, CA) were used to discriminate the Chinese liquor age which has a great economic value. Of a total of 21 major aroma components identified and quantified, 13 componen...

journal_title：Scientific reports

authors： Xu ML,Yu Y,Ramaswamy HS,Zhu SM

更新日期：2017-01-06 00:00:00

abstract：:Two-dimensional (2D) cell cultures growing on plastic do not recapitulate the three dimensional (3D) architecture and complexity of human tumors. More representative models are required for drug discovery and validation. Here, 2D culture and 3D mono- and stromal co-culture models of increasing complexity have been est...

journal_title：Scientific reports

authors： Stock K,Estrada MF,Vidic S,Gjerde K,Rudisch A,Santo VE,Barbier M,Blom S,Arundkar SC,Selvam I,Osswald A,Stein Y,Gruenewald S,Brito C,van Weerden W,Rotter V,Boghaert E,Oren M,Sommergruber W,Chong Y,de Hoogt R,Grae

更新日期：2016-07-01 00:00:00

abstract：:We used swept-source (SS) optical coherence tomography (OCT) and OCT angiography (OCTA) to investigate the effects of moderate physical exercise on retinal and choroidal vessel densities (VDs) and thicknesses in children. One eye in each of 40 myopic children (mean age, 11.70 years) and 18 emmetropic children (mean ag...

journal_title：Scientific reports

authors： Li S,Pan Y,Xu J,Li X,Spiegel DP,Bao J,Chen H

更新日期：2021-01-21 00:00:00

abstract：:The brain lacks a traditional lymphatic system for metabolite clearance. The existence of a "glymphatic system" where metabolites are removed from the brain's extracellular space by convective exchange between interstitial fluid (ISF) and cerebrospinal fluid (CSF) along the paravascular spaces (PVS) around cerebral bl...

journal_title：Scientific reports

authors： Kedarasetti RT,Drew PJ,Costanzo F

更新日期：2020-06-22 00:00:00

abstract：:We perform this meta-analysis to compare the efficacy and safety of cryoablation versus radiofrequency ablation for patients with cavotricuspid valve isthmus dependent atrial flutter. By searching EMBASE, MEDLINE, PubMed and Cochrane electronic databases from March 1986 to September 2014, 7 randomized clinical trials ...

journal_title：Scientific reports

authors： Chen YH,Lin H,Xie CL,Zhang XT,Li YG

更新日期：2015-06-03 00:00:00

abstract：:Surface enhanced Raman scattering (SERS) is generally and widely used to enhance the vibrational fingerprint of molecules located at the vicinity of noble metal nanoparticles. In this work, SERS is originally used to enhance the own vibrational density of states (VDOS) of nude and isolated gold nanoparticles. This off...

journal_title：Scientific reports

authors： Carles R,Benzo P,Pécassou B,Bonafos C

更新日期：2016-12-16 00:00:00

abstract：:Improving dewaterability of sludge is important for the disposal of sludge in wastewater treatment plants (WWTPs). This study, for the first time, investigated the Fe(II) activated oxidization processes in improving anaerobically digested sludge (ADS) dewaterability. The combination of Fe(II) (0-100 mg/g total solids ...

journal_title：Scientific reports

authors： Song K,Zhou X,Liu Y,Gong Y,Zhou B,Wang D,Wang Q

更新日期：2016-04-25 00:00:00

abstract：:The potential for epigenetic changes in host cells following microbial infection has been widely suggested, but few examples have been reported. We assessed genome-wide patterns of DNA methylation in human macrophage-like U937 cells following infection with Burkholderia pseudomallei, an intracellular bacterial pathoge...

journal_title：Scientific reports

authors： Cizmeci D,Dempster EL,Champion OL,Wagley S,Akman OE,Prior JL,Soyer OS,Mill J,Titball RW

更新日期：2016-08-03 00:00:00

abstract：:Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and the depletion of the glutathione (GSx) stores in neural tissue. The use of N-acetylcysteine (NAC) has been recently p...

journal_title：Scientific reports

authors： Faria M,Prats E,Gómez-Canela C,Hsu CY,Arick MA 2nd,Bedrossiantz J,Orozco M,Garcia-Reyero N,Ziv T,Ben-Lulu S,Admon A,Gómez-Oliván LM,Raldúa D

更新日期：2019-11-11 00:00:00

abstract：:Monoclonal antibodies (mAbs) are attractive therapeutics for treating a wide range of human disorders, and bind to the antigen through their complementarity-determining regions (CDRs). Small stable proteins containing structurally retained CDRs are promising alternatives to mAbs. In this report, we present a method to...

journal_title：Scientific reports

authors： Kadonosono T,Yimchuen W,Ota Y,See K,Furuta T,Shiozawa T,Kitazawa M,Goto Y,Patil A,Kuchimaru T,Kizaka-Kondoh S

更新日期：2020-01-21 00:00:00