Abstract：
:Everyone experiences common events differently. This leads to personal memories that presumably provide neural signatures of individual identity when events are reimagined. We present initial evidence that these signatures can be read from brain activity. To do this, we progress beyond previous work that has deployed generic group-level computational semantic models to distinguish between neural representations of different events, but not revealed interpersonal differences in event representations. We scanned 26 participants' brain activity using functional Magnetic Resonance Imaging as they vividly imagined themselves personally experiencing 20 common scenarios (e.g., dancing, shopping, wedding). Rather than adopting a one-size-fits-all approach to generically model scenarios, we constructed personal models from participants' verbal descriptions and self-ratings of sensory/motor/cognitive/spatiotemporal and emotional characteristics of the imagined experiences. We demonstrate that participants' neural representations are better predicted by their own models than other peoples'. This showcases how neuroimaging and personalized models can quantify individual-differences in imagined experiences.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Anderson AJ,McDermott K,Rooks B,Heffner KL,Dodell-Feder D,Lin FVdoi
10.1038/s41467-020-19630-ysubject
Has Abstractpub_date
2020-11-20 00:00:00pages
5916issue
1issn
2041-1723pii
10.1038/s41467-020-19630-yjournal_volume
11pub_type
杂志文章abstract：:Although substantial progress has been made in cancer biology and treatment, clinical outcomes of bladder carcinoma (BC) patients are still not satisfactory. The tumor microenvironment (TME) is a potential target. Here, by single-cell RNA sequencing on 8 BC tumor samples and 3 para tumor samples, we identify 19 differ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-18916-5
更新日期：2020-10-08 00:00:00
abstract：:Metal halide perovskites feature crystalline-like electronic band structures and liquid-like physical properties. The crystal-liquid duality enables optoelectronic devices with unprecedented performance and a unique opportunity to chemically manipulate the structure with low energy input. In this work, we leverage the...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-19009-z
更新日期：2020-10-16 00:00:00
abstract：:Alcohol oxidation reactions are widely used for the preparation of aldehydes and ketones. The electrolysis of alcohols to carbonyl compounds have been underutilized owing to low efficiency. Herein, we report an electrochemical oxidation of various alcohols in a continuous-flow reactor without external oxidants, base o...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-10928-0
更新日期：2019-06-26 00:00:00
abstract：:Various viruses enter host cells via endocytosis, but the molecular mechanisms underlying the specific internalization pathways remain unclear. Here we show that influenza A viruses (IAVs) enter cells via redundant pathways of clathrin-mediated and clathrin-independent endocytosis, with intracellular Ca(2+) having a c...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms3763
更新日期：2013-01-01 00:00:00
abstract：:Despite the fundamental importance of efficient and selective synthesis of widely useful alkylarenes, the direct catalytic C(sp2)-H alkylation of unactivated arenes with a readily available alkyl halide remains elusive. Here, we report the catalytic C(sp2)-H alkylation reactions of unactivated arenes with alkyl bromid...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-19038-8
更新日期：2020-10-19 00:00:00
abstract：:During meiosis, homologous chromosomes synapse and recombine at sites marked by the binding of the mismatch repair protein MLH1. In hexaploid wheat, the Ph1 locus has a major effect on whether crossover occurs between homologues or between related homoeologues. Here we report that--in wheat-rye hybrids where homologue...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms5580
更新日期：2014-08-06 00:00:00
abstract：:Efficient organic light-emitting diodes have been developed using emitters containing rare metals, such as platinum and iridium complexes. However, there is an urgent need to develop emitters composed of more abundant materials. Here we show a thermally activated delayed fluorescence material for organic light-emittin...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms9476
更新日期：2015-10-19 00:00:00
abstract：:The leaf economics spectrum (LES) describes consistent correlations among a variety of leaf traits that reflect a gradient from conservative to acquisitive plant strategies. So far, whether the LES holds in wetland plants at a global scale has been unclear. Using data on 365 wetland species from 151 studies, we find t...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-18354-3
更新日期：2020-09-09 00:00:00
abstract：:Sphingomyelin phosphodiesterase acid-like 3b (SMPDL3b) is a lipid raft enzyme that regulates plasma membrane (PM) fluidity. Here we report that SMPDL3b excess, as observed in podocytes in diabetic kidney disease (DKD), impairs insulin receptor isoform B-dependent pro-survival insulin signaling by interfering with insu...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-10584-4
更新日期：2019-06-19 00:00:00
abstract：:Homologous recombination deficiency (HRD) is a defining characteristic in BRCA-deficient breast tumors caused by genetic or epigenetic alterations in key pathway genes. We investigated the frequency of BRCA1 promoter hypermethylation in 237 triple-negative breast cancers (TNBCs) from a population-based study using rep...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-17537-2
更新日期：2020-07-27 00:00:00
abstract：:Foxp3+ regulatory T (Treg) cells are essential for maintaining peripheral tolerance and preventing autoimmunity. While genetic factors may predispose for autoimmunity, additional environmental triggers, such as viral infections, are usually required to initiate the onset of disease. Here, we show that viral infection ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-15309-6
更新日期：2020-03-23 00:00:00
abstract：:Subduction zone magmas are more oxidised on eruption than those at mid-ocean ridges. This is attributed either to oxidising components, derived from subducted lithosphere (slab) and added to the mantle wedge, or to oxidation processes occurring during magma ascent via differentiation. Here we provide direct evidence f...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-05804-2
更新日期：2018-08-29 00:00:00
abstract：:How developmental programs reactivate in regeneration is a fundamental question in biology. We addressed this question through the study of Wound Induced Hair follicle Neogenesis (WIHN), an adult organogenesis model where stem cells regenerate de novo hair follicles following deep wounding. The exact mechanism is unce...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-10811-y
更新日期：2019-06-26 00:00:00
abstract：:Many regulatory and signaling proteins have multiple modification sites. In bacterial chemotaxis, each chemoreceptor has multiple methylation sites that are responsible for adaptation. However, whether the ordering of the multisite methylation process affects adaptation remains unclear. Furthermore, the benefit of hav...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-16644-4
更新日期：2020-06-08 00:00:00
abstract：:For over 50 years, the great tit (Parus major) has been a model species for research in evolutionary, ecological and behavioural research; in particular, learning and cognition have been intensively studied. Here, to provide further insight into the molecular mechanisms behind these important traits, we de novo assemb...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms10474
更新日期：2016-01-25 00:00:00
abstract：:Macrophages play crucial roles in host defence and tissue homoeostasis, processes in which both environmental stimuli and intracellularly generated metabolites influence activation of macrophages. Activated macrophages are classified into M1 and M2 macrophages. It remains unclear how intracellular nutrition sufficienc...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms13130
更新日期：2016-10-12 00:00:00
abstract：:In the original version of this Article, an incorrect sample size was provided for the number of relict species (443 instead of 442) and the number of relict forests (423 instead of 422). These errors have been corrected in both the PDF and HTML versions of the Article. ...
journal_title：Nature communications
pub_type： 杂志文章,已发布勘误
doi：10.1038/s41467-018-07727-4
更新日期：2018-12-04 00:00:00
abstract：:Long duration gamma-ray bursts (GRBs), the brightest events since the Big Bang itself, are believed to originate in an ultra-relativistic jet breaking out from a massive stellar envelope. Despite decades of study, there is still no consensus on their emission mechanism. One unresolved question is the origin of the tig...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-09281-z
更新日期：2019-04-03 00:00:00
abstract：:Striated muscle contraction is regulated by the translocation of troponin-tropomyosin strands over the thin filament surface. Relaxation relies partly on highly-favorable, conformation-dependent electrostatic contacts between actin and tropomyosin, which position tropomyosin such that it impedes actomyosin association...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-15922-5
更新日期：2020-05-15 00:00:00
abstract：:Interaction between light and matter results in new quantum states whose energetics can modify chemical kinetics. In the regime of ensemble vibrational strong coupling (VSC), a macroscopic number [Formula: see text] of molecular transitions couple to each resonant cavity mode, yielding two hybrid light-matter (polarit...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-12636-1
更新日期：2019-10-15 00:00:00
abstract：:Polarization-driven resistive switching in ferroelectric tunnel junctions (FTJs)--structures composed of two electrodes separated by an ultrathin ferroelectric barrier--offers new physics and materials functionalities, as well as exciting opportunities for the next generation of non-volatile memories and logic devices...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms6518
更新日期：2014-11-24 00:00:00
abstract：:Intestinal intraepithelial T cells contribute to the regulation of inflammatory responses in the intestine; however, the molecular basis for their development and maintenance is unknown. The aryl hydrocarbon receptor complexes with the aryl hydrocarbon receptor nuclear translocator (ARNT) and senses environmental fact...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms3112
更新日期：2013-01-01 00:00:00
abstract：:Dynamics are fundamental to the functions of biomolecules and can occur on a wide range of time and length scales. Here we develop and apply high-speed AFM height spectroscopy (HS-AFM-HS), a technique whereby we monitor the sensing of a HS-AFM tip at a fixed position to directly detect the motions of unlabeled molecul...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-07512-3
更新日期：2018-11-26 00:00:00
abstract：:This corrects the article DOI: 10.1038/ncomms15317. ...
journal_title：Nature communications
pub_type： 杂志文章,已发布勘误
doi：10.1038/ncomms16128
更新日期：2017-06-30 00:00:00
abstract：:Atropisomers are important organic frameworks in bioactive natural products, drugs as well as chiral catalysts. Meanwhile, silanols display unique properties compared to their alcohol analogs, however, the catalytic synthesis of atropisomers bearing silanol groups is challenging. Here, we show a rhodium-catalyzed tors...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-18273-3
更新日期：2020-09-07 00:00:00
abstract：:Oceanic anoxic events have been associated with warm climates in Earth history, and there are concerns that current ocean deoxygenation may eventually lead to anoxia. Here we show results of a multi-millennial global-warming simulation that reveal, after a transitory deoxygenation, a marine oxygen inventory 6% higher ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-10813-w
更新日期：2019-06-26 00:00:00
abstract：:The interoceanic transfer of seawater between the Indian Ocean and the Atlantic, 'Agulhas leakage', forms a choke point for the overturning circulation in the global ocean. Here, by combining output from a series of high-resolution ocean and climate models with in situ and satellite observations, we construct a time s...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms10082
更新日期：2015-12-10 00:00:00
abstract：:Transcription of eukaryotic protein-coding genes requires passage of RNA polymerase II (Pol II) through nucleosomes, but it is unclear how this is achieved. Here we report the cryo-EM structure of transcribing Saccharomyces cerevisiae Pol II engaged with a downstream nucleosome core particle at an overall resolution o...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-07870-y
更新日期：2018-12-21 00:00:00
abstract：:Type I CRISPR-Cas loci provide prokaryotes with a nucleic-acid-based adaptive immunity against foreign DNA. Immunity involves adaptation, the integration of ~30-bp DNA fragments, termed prespacers, into the CRISPR array as spacers, and interference, the targeted degradation of DNA containing a protospacer. Interferenc...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-12417-w
更新日期：2019-10-10 00:00:00
abstract：:The cell adhesion molecule Neuroligin2 (NL2) is localized selectively at GABAergic synapses, where it interacts with the scaffolding protein gephyrin in the post-synaptic density. However, the role of this interaction for formation and plasticity of GABAergic synapses is unclear. Here, we demonstrate that endogenous N...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms6066
更新日期：2014-10-09 00:00:00
