Abstract:
:A protein immunologically identical to the major basic protein (MBP) of eosinophil granules is present in the plasma of pregnant women and has been localized to human placental X cells using immunofluorescence. This study demonstrates the presence of similar immunoreactive molecules in the placental X cells from several non-human primates. We also describe the presence of increased plasma levels of MBP in the pregnant gorilla and in pregnant cynomolgus and rhesus monkeys as compared to non-pregnant counterparts. Such findings suggest that non-human primates are a suitable animal model for the study of the X cell function and in particular the physiological importance of MBP in pregnancy.
journal_name
Placentajournal_title
Placentaauthors
Wasmoen TL,Benirschke K,Gleich GJdoi
10.1016/0143-4004(87)90052-xsubject
Has Abstractpub_date
1987-05-01 00:00:00pages
283-92issue
3eissn
0143-4004issn
1532-3102pii
0143-4004(87)90052-Xjournal_volume
8pub_type
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