Angiotensin II and its different receptor subtypes in placenta and fetal membranes.

abstract：BACKGROUND:In humans, it is known that blood flow is directed to the gravid uterus from two (right and left) pelvic uterine arteries. The extent of supply from the tubo-ovarian anastomosis (joining of the ovarian and uterine arteries) is unknown. The aim of this study was to delineate the arterial blood supply to the p...

journal_title：Placenta

authors： Balasuriya H,Bell P,Waugh R,Thompson J,Gillin A,Hennessy A,Makris A

更新日期：2010-01-01 00:00:00

abstract：:Endotheliochorial placentas occur in orders from all four major clades of eutherian mammal. Species with this type of placenta include one of the smallest (pygmy shrew) and largest (African elephant) land mammals. The endotheliochorial placenta as a definitive form has an interhemal area consisting of maternal endothe...

journal_title：Placenta

authors： Enders AC,Carter AM

更新日期：2012-05-01 00:00:00

abstract：:The implantation of the blastocyst and early development of the placenta are crucial for the success of implantation and pregnancy. However, the formative stages of human placental development are largely unknown because of their existence in a 'black box' where access to samples is extremely limited for ethical reaso...

journal_title：Placenta

authors： James JL,Carter AM,Chamley LW

更新日期：2012-05-01 00:00:00

abstract：:This study examines the vasorelaxation of isolated human placental chorionic plate arteries and the perfused fetal-placental vasculature, in vitro, to a variety of nitrovasodilator compounds including glyceryl trinitrate (GTN) sodium nitroprusside (SNP), S-nitroso-N-acetylpenicillamine (SNAP), S-nitroso-N-glutathione ...

journal_title：Placenta

authors： Zhang XQ,Kwek K,Read MA,Donoghue JF,Walters WA

更新日期：2001-04-01 00:00:00

abstract：INTRODUCTION:Maternal nutrition is an extremely important health issue. We evaluated the impact of maternal high fat diet (HFD) on pregnancy outcomes, elucidated how the rat placenta and fetus respond to diet manipulation based on fetal sex, and identified candidate genes and pathways. METHODS:Rats were fed a normal o...

journal_title：Placenta

authors： Lin YJ,Huang LT,Tsai CC,Sheen JM,Tiao MM,Yu HR,Lin IC,Tain YL

更新日期：2019-03-01 00:00:00

abstract：:During pregnancy, leptin concentrations in the maternal circulation are elevated in both humans and rodents but decrease to pre-pregnancy levels at birth, suggesting a role for leptin in the maintenance of pregnancy. Synthesis of leptin by the human placenta is established but whether the murine placenta synthesizes l...

journal_title：Placenta

authors： Malik NM,Carter ND,Wilson CA,Scaramuzzi RJ,Stock MJ,Murray JF

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Receptor-activator of NF-κB ligand (TNFSF11, also known as RANKL) and its receptor RANK are essential regulators on bone remodeling, mammary gland development and hormone-associated breast cancer development. However, the expression pattern and role of RANKL/RANK axis in decidual stromal cells (DSCs) are uncl...

journal_title：Placenta

authors： Meng YH,Li H,Chen X,Liu LB,Shao J,Chang KK,Du MR,Jin LP,Li MQ,Li DJ

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:To compare the distribution of placental protein 13 (PP13) in fetal and maternal blood and amnionic fluid and to correlate it with PP13 protein and mRNA in the placenta. METHODS:Umbilical arterial serum, amnionic fluid, maternal venous serum and placental tissues were collected from normal outcome pregnanci...

journal_title：Placenta

authors： Sammar M,Nisemblat S,Fleischfarb Z,Golan A,Sadan O,Meiri H,Huppertz B,Gonen R

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Histologic placental and/or intra-amniotic inflammation is frequently documented during ascending intra-uterine infections in patients with preterm labor and intact membranes. Placenta previa can be a clinical situation that shows the successive schema of histologic placental and intra-amniotic inflammation d...

journal_title：Placenta

authors： Park CW,Moon KC,Park JS,Jun JK,Yoon BH

更新日期：2009-07-01 00:00:00

abstract：:Chemokines are small polypeptides that attract specific leukocyte subsets by binding to cell-surface receptors. In reproductive biology, they have been implicated in ovulation, menstruation, and embryo implantation, and pathological processes such as preterm delivery, HIV infection, and endometriosis. It is known that...

journal_title：Placenta

authors： Dominguez F,Pellicer A,Simon C

更新日期：2003-10-01 00:00:00

abstract：:Prior studies have shown that levels of corticotrophin-releasing hormone (CRH) in the umbilical cord blood of infants born after pregnancies complicated by pre-eclampsia are significantly higher than fetal plasma CRH concentrations in uncomplicated pregnancies. In the present study we have measured CRH by radioimmunoa...

journal_title：Placenta

authors： Goland RS,Conwell IM,Jozak S

更新日期：1995-06-01 00:00:00

abstract：:During early pregnancy, intermediate (extravillous) trophoblast infiltrates the basal plate and invades the spiral arteries, a physiological process required to establish the maternal-fetal circulation. Immunostaining studies have shown that differentiation of trophoblast into this invasive subpopulation is associated...

journal_title：Placenta

authors： Shih IeM,Hsu MY,Oldt RJ 3rd,Herlyn M,Gearhart JD,Kurman RJ

更新日期：2002-11-01 00:00:00

abstract：:Despite the vital and diverse roles of the placenta, remarkably little is known about its actual composition. Moreover, as placentophagy becomes increasingly popular, understanding the nutritional and heavy metal composition of the human placenta has practical implications. Here we evaluated the carbohydrate, sugar, p...

journal_title：Placenta

authors： Chang S,Lodico L,Williams Z

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:Preterm birth is a heterogeneous phenotype, with placental abnormalities underlying many cases. The etiology of preterm births that occur in the absence of placental abnormalities, however, remain enigmatic and we considered that early pregnancy biomarkers may provide clues. METHODS:Women from a hospital-...

journal_title：Placenta

authors： Sun B,Parks WT,Simhan HN,Bertolet M,Catov JM

更新日期：2020-01-01 00:00:00

abstract：:The human placenta contains two types of 11beta-hydroxysteroid dehydrogenase (11beta-HSD). The exclusive oxidase 11beta-HSD2 has been suggested to protect the fetus from high levels of maternal glucocorticoids by converting cortisol to inactive cortisone. Perfused term human placenta was used to examine the activity o...

journal_title：Placenta

authors： Sun K,Adamson SL,Yang K,Challis JR

更新日期：1999-01-01 00:00:00

abstract：:Ovarian, endometrial and breast cancers are associated with several risk factors, such as low parity, infertility, early age at menarche, and late age at menopause. Frequently most of these risk factors coexist in infertile patients and some studies suggested that the different infertility causes can be involved in ca...

journal_title：Placenta

authors： Cetin I,Cozzi V,Antonazzo P

更新日期：2008-10-01 00:00:00

abstract：:In primates and rodents, trophoblast cells synthesize and secrete into the maternal circulation a family of proteins known as pregnancy specific glycoproteins (PSG). The current study was undertaken to characterize the receptor for two members of the murine PSG family, PSG17 and PSG23. Binding of recombinant PSG17 and...

journal_title：Placenta

authors： Sulkowski GN,Warren J,Ha CT,Dveksler GS

更新日期：2011-08-01 00:00:00

abstract：:Use of cocaine during pregnancy is known to have harmful effects on the mother and her fetus. Currently available models describing the pathogenesis of these effects focus on the involvement of cocaine target systems, primarily the noradrenaline transporter, in the mother and the fetus. The placenta which lies between...

journal_title：Placenta

authors： Ganapathy V,Leibach FH

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are small single-stranded RNA molecules working as post-transcriptional modulators of gene expression. Trophoblast cells are a heterogenous group of fetal cells forming the feto-maternal interface and displaying a wide spectrum of functions. The regulation of their behavior may partly unde...

journal_title：Placenta

authors： Morales-Prieto DM,Chaiwangyen W,Ospina-Prieto S,Schneider U,Herrmann J,Gruhn B,Markert UR

更新日期：2012-09-01 00:00:00

abstract：:Maternal feed allowance during pregnancy can affect the development of the ovine placenta and fetus. The impact of variations in feed allowance prior to as well as throughout pregnancy has received less attention. Ewes were offered 0.6 (R), 1.2 (C) or 1.8 (AL) maintenance requirements from 89 days before conception un...

journal_title：Placenta

authors： Quigley SP,Kleemann DO,Walker SK,Speck PA,Rudiger SR,Nattrass GS,DeBlasio MJ,Owens JA

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Discrepancies in the results from studies of early events in human trophoblast invasion of decidua have been acknowledged and are attributed largely to deficiencies in the accuracy of sampling of the decidual tissue used in the research. We describe a novel technique of biopsy of decidua parietalis and basal...

journal_title：Placenta

authors： Talaulikar VS,Bax BE,Page NM,Manyonda I

更新日期：2012-06-01 00:00:00

abstract：:Human endothelial dysfunction is a common feature in many diseases of pregnancy, such as gestational diabetes (GD). Metabolic changes include abnormal synthesis of nitric oxide (NO) and abnormal membrane transport of l-arginine and adenosine in primary cultures of human umbilical vein (HUVEC, macrovascular) and placen...

journal_title：Placenta

authors： Sobrevia L,Abarzúa F,Nien JK,Salomón C,Westermeier F,Puebla C,Cifuentes F,Guzmán-Gutiérrez E,Leiva A,Casanello P

更新日期：2011-03-01 00:00:00

abstract：:The possible roles of the allantoic sac in metabolism of uteroferrin, the iron-containing, purple phosphatase, were examined. This protein, which originates in the maternal endometrium, was measured in allantoic fluid by a specific double-antibody radioimmunoassay and by its beta-mercaptoethanol-activated acid phospha...

journal_title：Placenta

authors： Buhi WC,Ducsay CA,Bartol FF,Bazer FW,Roberts RM

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether DNA-associated micro-particles (MPs) in maternal plasma express fetal-derived human leukocyte antigen-G (HLA-G) or placental alkaline phosphatase (PLAP) and whether the levels differ between women with normotensive pregnancies and preeclampsia. METHODS:DNA-asso...

journal_title：Placenta

authors： Orozco AF,Jorgez CJ,Ramos-Perez WD,Popek EJ,Yu X,Kozinetz CA,Bischoff FZ,Lewis DE

更新日期：2009-10-01 00:00:00

abstract：:The deportation of trophoblast debris from the placenta was first documented over 100 years ago, and today we know that the deported material ranges from multinucleated syncytial knots/sprouts to trophoblast-derived nanoparticles. However little is known about the effect of trophoblast debris on maternal physiology si...

journal_title：Placenta

authors： Pantham P,Askelund KJ,Chamley LW

更新日期：2011-10-01 00:00:00

abstract：:Amino acid transport System A (SysA) activity is present within the rodent and human placentas. Inhibition of this transport system is associated with fetal growth retardation. Several cDNAs encoding SysA transport proteins have been discovered, and their presence documented within the human placenta. We have demonstr...

journal_title：Placenta

authors： Novak D,Lehman M,Bernstein H,Beveridge M,Cramer S

更新日期：2006-04-01 00:00:00

abstract：:During the first trimester of pregnancy the human placenta develops in an hypoxic environment caused by the occlusion of uterine spiral arterioles by extravillous trophoblasts (EVT). This period of low oxygen tension is crucial for successful pregnancy. In low oxygen environments, Hypoxia Inducible Factors (HIF) are t...

journal_title：Placenta

authors： Patel J,Landers K,Mortimer RH,Richard K

更新日期：2010-11-01 00:00:00

abstract：:Intrauterine growth and development can impact upon the long-term health of an individual. The fetus is dependent upon the placenta for its supply of nutrients and oxygen from the mother. In turn, the functional capacity of the placenta to supply that demand is under the control of the fetal and maternal genomes. Rece...

journal_title：Placenta

authors： Angiolini E,Fowden A,Coan P,Sandovici I,Smith P,Dean W,Burton G,Tycko B,Reik W,Sibley C,Constância M

更新日期：2006-04-01 00:00:00

abstract：:Several recent publications have focused on the association between the occurrence of twin-to-twin transfusion syndrome (TTTS) in diamniotic-monochorionic twins and the presence of a number of selected anatomic placental characteristics (distribution of vascular territory, cord insertion, type and number of inter-twin...

journal_title：Placenta

authors： De Paepe ME,DeKoninck P,Friedman RM

更新日期：2005-07-01 00:00:00

abstract：:Apart from during the prepartal period, the main oestrogen produced by the bovine trophoblast is oestrone sulphate (E1S) which does not bind to nuclear oestrogen receptors (ER). High steroid sulphatase (StS) activities previously detected in the maternal part of bovine placentomes (caruncles) suggest the local activat...

journal_title：Placenta

authors： Greven H,Kowalewski MP,Hoffmann B,Geyer J,Rex-Haffner M,Ugele B,Schuler G

更新日期：2007-08-01 00:00:00