Genetic analysis of the molecular regulation of electric fields-guided glia migration.

abstract：:The extreme miniaturization of biological and chemical assays in aqueous-droplet compartments enables spatiotemporal control for large-scale parallel experimentation and can thus permit new capabilities for "digitizing" directed molecular evolution methodologies. We report a remarkably facile bulk method to generate m...

journal_title：Scientific reports

authors： Sharma B,Takamura Y,Shimoda T,Biyani M

更新日期：2016-05-20 00:00:00

abstract：:Macro-fungi play important roles in the soil elemental cycle in terrestrial ecosystems. Many researchers have focused on the interactions between mycorrhizal fungi and host plants, whilst comparatively few studies aim to characterise the relationships between macro-fungi and bacteria in situ. In this study, we detecte...

journal_title：Scientific reports

authors： Liu Y,Sun Q,Li J,Lian B

更新日期：2018-08-03 00:00:00

abstract：:The standard treatment for most acute myeloid leukemia (AML) is chemotherapy, which is often associated with severe adverse effects. One strategy to reduce the adverse effects is targeted therapy that can selectively deliver anticancer drugs to tumor cells. Immature laminin receptor protein (OFA/iLRP) is a potential t...

journal_title：Scientific reports

authors： An Y,Hu Y,Li X,Li Z,Duan J,Yang XD

更新日期：2019-05-14 00:00:00

abstract：:Membrane-embedded proteins are critical to the establishment, survival and persistence in the host of the Lyme disease bacterium Borrelia burgdorferi (Bb), but to date, there are no solved structures of transmembrane proteins representing these attractive therapeutic targets. All available structures from the genus Bo...

journal_title：Scientific reports

authors： Robertson KE,Truong CD,Craciunescu FM,Yang JH,Chiu PL,Fromme P,Hansen DT

更新日期：2019-11-26 00:00:00

abstract：:Finding strategies to preserve quantum resources in open systems is nowadays a main requirement for reliable quantum-enhanced technologies. We address this issue by considering structured cavities embedding qubits driven by a control technique known as frequency modulation. We first study a single qubit in a lossy cav...

journal_title：Scientific reports

authors： Mortezapour A,Lo Franco R

更新日期：2018-09-24 00:00:00

abstract：:Metal-organic frameworks (MOFs) are intriguing host materials in composite electrolytes due to their ability for tailoring host-guest interactions by chemical tuning of the MOF backbone. Here, we introduce particularly high sodium ion conductivity into the zeolitic imidazolate framework ZIF-8 by impregnation with the ...

journal_title：Scientific reports

authors： Nozari V,Calahoo C,Tuffnell JM,Adelhelm P,Wondraczek K,Dutton SE,Bennett TD,Wondraczek L

更新日期：2020-02-26 00:00:00

abstract：:The recent reaching of 20% of conversion efficiency by solar cells based on metal hybrid perovskites (MHP), e.g., the methylammonium (MA) lead iodide, CH3NH3PbI3 (MAPbI3), has excited the scientific community devoted to the photovoltaic materials. However, the toxicity of Pb is a hindrance for large scale commercial o...

journal_title：Scientific reports

authors： Guedes-Sobrinho D,Guilhon I,Marques M,Teles LK

更新日期：2019-07-30 00:00:00

abstract：:Control of parasite transmission is critical for the eradication of malaria. However, most antimalarial drugs are not active against P. falciparum gametocytes, responsible for the spread of malaria. Consequently, patients can remain infectious for weeks after the clearance of asexual parasites and clinical symptoms. H...

journal_title：Scientific reports

authors： Sun W,Tanaka TQ,Magle CT,Huang W,Southall N,Huang R,Dehdashti SJ,McKew JC,Williamson KC,Zheng W

更新日期：2014-01-17 00:00:00

abstract：:An investigation was carried out to assess the effect of the P content on the microstructure and mechanical properties of ZCuPb20Sn5 alloy. Alloys of various compositions, (0.05, 0.1, 0.2, 0.3, 0.5% wt.% P) were melted in a melting furnace under 1200 °C and cast into metal mould, the hardness, strength and elongation ...

journal_title：Scientific reports

authors： Ren XY,Zhang X,Hong X,Ren J

更新日期：2019-09-16 00:00:00

abstract：:The study of postsynaptic excitation to inhibition (E/I ratio) imbalances in human brain diseases, is a highly relevant functional measurement poorly investigated due to postmortem degradation of synaptic receptors. We show that near-simultaneous recording of microtransplanted synaptic receptors after simulated morgue...

journal_title：Scientific reports

authors： Scaduto P,Sequeira A,Vawter MP,Bunney W,Limon A

更新日期：2020-05-25 00:00:00

abstract：:The establishment of a healthy gastrointestinal milieu may not only offer an opportunity to reduce swine production costs but could also open the way for a lifetime of human health improvement. This study investigates the effects of feeding soluble fibre from flaxseed meal-containing diet (FM) and insoluble fibre from...

journal_title：Scientific reports

authors： Ndou SP,Tun HM,Kiarie E,Walsh MC,Khafipour E,Nyachoti CM

更新日期：2018-04-12 00:00:00

abstract：:Why humans cooperate in large groups and with non-kin remains a puzzle for researchers across the natural and social sciences. Investigating whether cooperation is sexually selected could contribute to an understanding of the evolution of human cooperation. Competition for access to mates could indeed select for coope...

journal_title：Scientific reports

authors： Tognetti A,Dubois D,Faurie C,Willinger M

更新日期：2016-07-14 00:00:00

abstract：:Modulation of photoluminescence of atomically thin transition metal dichalcogenide two-dimensional materials is critical for their integration in optoelectronic and photonic device applications. By coupling with different plasmonic array geometries, we have shown that the photoluminescence intensity can be enhanced an...

journal_title：Scientific reports

authors： Mukherjee B,Kaushik N,Tripathi RP,Joseph AM,Mohapatra PK,Dhar S,Singh BP,Kumar GV,Simsek E,Lodha S

更新日期：2017-01-30 00:00:00

abstract：:Phelan-McDermid Syndrome (PMS), which is defined by a deletion within 22q13, demonstrates significant phenotypic variation. Given that six mitochondrial genes are located within 22q13, including complex I and IV genes, we hypothesize that mitochondrial complex activity abnormalities may explain phenotypic variation in...

journal_title：Scientific reports

authors： Frye RE,Cox D,Slattery J,Tippett M,Kahler S,Granpeesheh D,Damle S,Legido A,Goldenthal MJ

更新日期：2016-01-29 00:00:00

abstract：:Antimonite [Sb(III)]-oxidizing bacteria can transform the toxic Sb(III) into the less toxic antimonate [Sb(V)]. Recently, the cytoplasmic Sb(III)-oxidase AnoA and the periplasmic arsenite [As(III)] oxidase AioAB were shown to responsible for bacterial Sb(III) oxidation, however, disruption of each gene only partially ...

journal_title：Scientific reports

authors： Li J,Yang B,Shi M,Yuan K,Guo W,Wang Q,Wang G

更新日期：2017-03-02 00:00:00

abstract：:We isolated a novel bacterial strain from a prokaryotic consortium associated to the psychrophilic marine ciliate Euplotes focardii, endemic of the Antarctic coastal seawater. The 16S rDNA sequencing and the phylogenetic analysis revealed the close evolutionary relationship to the Antarctic marine bacterium Marinomona...

journal_title：Scientific reports

authors： John MS,Nagoth JA,Ramasamy KP,Ballarini P,Mozzicafreddo M,Mancini A,Telatin A,Liò P,Giuli G,Natalello A,Miceli C,Pucciarelli S

更新日期：2020-06-23 00:00:00

abstract：:Data on post stroke outcomes in developing countries are scarce due to uncoordinated healthcare delivery systems. In Malaysia, the national stroke clinical practice guideline does not address transfer of care and longer term post stroke care beyond tertiary care. Hence, post stroke care delivery may be delivered at ei...

journal_title：Scientific reports

authors： Abdul Aziz AF,Ali MF,Yusof MF,Che' Man Z,Sulong S,Aljunid SM

更新日期：2018-12-19 00:00:00

abstract：:Once activated, the intracellular receptor NLRP3 assembles an inflammasome protein complex that facilitates the caspase-1-mediated maturation of IL-1β and IL-18. Inactive NLRP3 is guarded by a protein complex containing Hsp90. In response to stress stimuli, Hsp90 is released, and NLRP3 can be activated to promote infl...

journal_title：Scientific reports

authors： Piippo N,Korhonen E,Hytti M,Skottman H,Kinnunen K,Josifovska N,Petrovski G,Kaarniranta K,Kauppinen A

更新日期：2018-04-30 00:00:00

abstract：:The high hydrophobicity of poly(vinylidene fluoride) (PVDF) membrane remains an obstacle to be applied in some purification processes of water or wastewater. Herein, a highly hydrophilic hybrid mesoporous titania membrane composed of mesoporous anatase titania (meso-TiO2) materials inside the three-dimensional (3D) ma...

journal_title：Scientific reports

authors： Wang M,Yang G,Jin P,Tang H,Wang H,Chen Y

更新日期：2016-01-12 00:00:00

abstract：:Many behaviors of cancer, such as progression, metastasis and drug resistance etc., cannot be fully understood by genetic mutations or intracellular signaling alone. Instead, they are emergent properties of the cell community which forms a tumor. Studies of tumor heterogeneity reveal that many cancer behaviors critica...

journal_title：Scientific reports

authors： Zhou JX,Taramelli R,Pedrini E,Knijnenburg T,Huang S

更新日期：2017-08-18 00:00:00

abstract：:Marine pollution is a significant issue in recent decades, with the increase in industries and their waste harming the environment and ecosystems. Notably, the rise in shellfish industries contributes to tons of shellfish waste composed of up to 58% chitin. Chitin, the second most ample polymer next to cellulose, is i...

journal_title：Scientific reports

authors： Subramanian K,Sadaiappan B,Aruni W,Kumarappan A,Thirunavukarasu R,Srinivasan GP,Bharathi S,Nainangu P,Renuga PS,Elamaran A,Balaraman D,Subramanian M

更新日期：2020-07-17 00:00:00

abstract：:PC4 is an abundant single-strand DNA binding protein that has been implicated in transcription and DNA repair. Here, we show that PC4 is involved in the cellular DNA damage response. To elucidate the role, we used the DT40 chicken B cell model, which produces clustered DNA lesions at Ig loci via the action of activati...

journal_title：Scientific reports

authors： Caldwell RB,Braselmann H,Schoetz U,Heuer S,Scherthan H,Zitzelsberger H

更新日期：2016-07-04 00:00:00

abstract：:Sensitive High-Resolution Ion Microprobe (SHRIMP) U-Pb analyses of zircons from Paleoarchean (~3.4 Ga) tonalite-gneiss called the Older Metamorphic Tonalitic Gneiss (OMTG) from the Champua area of the Singhbhum Craton, India, reveal 4.24-4.03 Ga xenocrystic zircons, suggesting that the OMTG records the hitherto unknow...

journal_title：Scientific reports

authors： Chaudhuri T,Wan Y,Mazumder R,Ma M,Liu D

更新日期：2018-05-04 00:00:00

abstract：:Despite the effectiveness of combined anti-retroviral therapy, human immunodeficiency virus (HIV) infected-patients frequently report diarrhea and neuropsychological deficits. It is claimed that the viral HIV-1 Trans activating factor (HIV-1 Tat) protein is responsible for both diarrhea and neurotoxic effects, but the...

journal_title：Scientific reports

authors： Esposito G,Capoccia E,Gigli S,Pesce M,Bruzzese E,D'Alessandro A,Cirillo C,di Cerbo A,Cuomo R,Seguella L,Steardo L,Sarnelli G

更新日期：2017-08-10 00:00:00

abstract：:High-throughput single-stranded DNA sequencing (ssDNA-seq) of cell-free DNA from plasma and other bodily fluids is a powerful method for non-invasive prenatal testing, and diagnosis of cancers and other diseases. Here, we developed a facile ssDNA-seq method, which exploits a novel template-switching activity of thermo...

journal_title：Scientific reports

authors： Wu DC,Lambowitz AM

更新日期：2017-08-21 00:00:00

abstract：:A mathematical model is proposed for the autonomic control of cardiovascular system, which takes into account two separated self-exciting sympathetic control loops of heart rate and peripheral vascular tone. The control loops are represented by self-exciting time-delay systems and their tone depends on activity of the...

journal_title：Scientific reports

authors： Ishbulatov YM,Karavaev AS,Kiselev AR,Simonyan MA,Prokhorov MD,Ponomarenko VI,Mironov SA,Gridnev VI,Bezruchko BP,Shvartz VA

更新日期：2020-10-05 00:00:00

abstract：:Nitrogen-Vacancy (NV) centers in diamond are promising solid-state quantum emitters that can be utilized for photonic quantum applications. Various diamond nanophotonic devices have been fabricated for efficient extraction of single photons emitted from NV centers to a single guided mode. However, for constructing sca...

journal_title：Scientific reports

authors： Yonezu Y,Wakui K,Furusawa K,Takeoka M,Semba K,Aoki T

更新日期：2017-10-11 00:00:00

abstract：:Mechanical forces are critical to modulate cell spreading, contractility, gene expression, and even stem cell differentiation. Yet, existing tools that can apply controllable subcellular forces to a large number of single cells simultaneously are still limited. Here we report a novel ultrasound tweezing cytometry util...

journal_title：Scientific reports

authors： Fan Z,Sun Y,Di Chen,Tay D,Chen W,Deng CX,Fu J

更新日期：2013-01-01 00:00:00

abstract：:Effective quality assurance is essential in any screening programme. This article provides a unique insight into key quality indicators of five rounds of the first population-based colorectal cancer screening programme implemented in Spain (2000-2012), providing the results according to the type of screening (prevalen...

journal_title：Scientific reports

authors： Binefa G,Garcia M,Milà N,Fernández E,Rodríguez-Moranta F,Gonzalo N,Benito L,Clopés A,Guardiola J,Moreno V

更新日期：2016-01-20 00:00:00

abstract：:Human NAD-dependent isocitrate dehydrogenase catalyzes the decarboxylation of isocitrate (ICT) into α-ketoglutarate in the Krebs cycle. It exists as the α2βγ heterotetramer composed of the αβ and αγ heterodimers. Previously, we have demonstrated biochemically that the α2βγ heterotetramer and αγ heterodimer can be allo...

journal_title：Scientific reports

authors： Ma T,Peng Y,Huang W,Ding J

更新日期：2017-01-18 00:00:00