Profile and outcome of post stroke patients managed at selected public primary care health centres in Peninsular Malaysia: A retrospective observational study.

Abstract:

:Data on post stroke outcomes in developing countries are scarce due to uncoordinated healthcare delivery systems. In Malaysia, the national stroke clinical practice guideline does not address transfer of care and longer term post stroke care beyond tertiary care. Hence, post stroke care delivery may be delivered at either tertiary or primary care facilities. This study aimed at describing patients' characteristics and outcomes of post stroke care delivered by the primary care teams at public primary care healthcentres across Peninsular Malaysia. Multi staged sampling was done to select public primary care health centres to recruit post stroke patients. At each health centre, convenience sampling was done to recruit adult patients (≥18 years) who received post stroke care between July-December 2012. Baseline measurements were recorded at recruitment and retrospective medical record review was done simultaneously, for details on medical and / or rehabilitation treatment at health centre. Changes in the measurements for post stroke care were compared using paired t-tests and Wilcoxon Rank test where appropriate. Total of 151 patients were recruited from ten public primary care healthcentres. The mean age at stroke presentation was 55.8 ± 9.8 years. Median duration of follow up was 2.3 (IQR 5.1) years. Majority co-resided with a relative (80.8%), and a family member was primary caregiver (75.%). Eleven percent were current smokers. Almost 71.0% of patients achieved BP ≤ 140/90 mmHg. Only 68.9% of the patients had been referred for neurorehabilitation. Percentage of recorded data was highest for blood pressure (88.1%) while lowest was HbA1c (43.0%). For clinical outcomes, systolic and diastolic blood pressure, triglyceride level and calculated GFR (eGFR) showed statistically significant changes during follow up (p < 0.05). Post stroke care at public primary care healthcentres showed benefits in stroke risk factors control (i.e. hypertension and dyslipidaemia) but deterioration in renal function. A more structured coordination is needed to optimise post stroke care beyond acute phase management for patients who reside at home in the community.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Abdul Aziz AF,Ali MF,Yusof MF,Che' Man Z,Sulong S,Aljunid SM

doi

10.1038/s41598-018-36154-0

subject

Has Abstract

pub_date

2018-12-19 00:00:00

pages

17965

issue

1

issn

2045-2322

pii

10.1038/s41598-018-36154-0

journal_volume

8

pub_type

杂志文章
  • Micelle-stabilized Olfactory Receptors for a Bioelectronic Nose Detecting Butter Flavors in Real Fermented Alcoholic Beverages.

    abstract::A bioelectronic nose device based on micelle-stabilized olfactory receptors is developed for the selective discrimination of a butter flavor substance in commercial fermented alcoholic beverages. In this work, we have successfully overexpressed ODR-10, a type of olfactory receptor, from Caenorhabditis elegans using a ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-65900-6

    authors: Shin N,Lee SH,Pham Ba VA,Park TH,Hong S

    更新日期:2020-06-03 00:00:00

  • Chloropicophyceae, a new class of picophytoplanktonic prasinophytes.

    abstract::Prasinophytes are a paraphyletic group of nine lineages of green microalgae that are currently classified either at the class or order level or as clades without formal taxonomic description. Prasinophyte clade VII comprises picoplanktonic algae that are important components of marine phytoplankton communities, partic...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-12412-5

    authors: Lopes Dos Santos A,Pollina T,Gourvil P,Corre E,Marie D,Garrido JL,Rodríguez F,Noël MH,Vaulot D,Eikrem W

    更新日期:2017-10-25 00:00:00

  • Revisiting metallization boundary of warm dense helium in a wide ρ-T regime from ab initio study.

    abstract::The knowledge of the metallization of warm dense helium has important implications for understanding the thermal histories, stellar structure and magnetic field environment of giant planets. However, it is also a pendent scientific topic. For a revisiting into the properties of warm dense helium, we performed extensiv...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41885

    authors: Zhang W,Li Z,Fu Z,Dai J,Chen Q,Cai L

    更新日期:2017-02-03 00:00:00

  • A bacterial acetyltransferase triggers immunity in Arabidopsis thaliana independent of hypersensitive response.

    abstract::Type-III secreted effectors (T3Es) play critical roles during bacterial pathogenesis in plants. Plant recognition of certain T3Es can trigger defence, often accompanied by macroscopic cell death, termed the hypersensitive response (HR). Economically important species of kiwifruit are susceptible to Pseudomonas syringa...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-03704-x

    authors: Jayaraman J,Choi S,Prokchorchik M,Choi DS,Spiandore A,Rikkerink EH,Templeton MD,Segonzac C,Sohn KH

    更新日期:2017-06-15 00:00:00

  • The estrogenicity of methylparaben and ethylparaben at doses close to the acceptable daily intake in immature Sprague-Dawley rats.

    abstract::The estrogenicity of parabens at human exposure levels has become a focus of concern due to the debate over whether the estrogenicity of parabens is strong enough to play a role in the increased incidence of breast cancer. In this study, the uterotrophic activities of methylparaben (MP) and ethylparaben (EP) at doses ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25173

    authors: Sun L,Yu T,Guo J,Zhang Z,Hu Y,Xiao X,Sun Y,Xiao H,Li J,Zhu D,Sai L,Li J

    更新日期:2016-04-28 00:00:00

  • Acoustic illusion near boundaries of arbitrary curved geometry.

    abstract::We have proposed a scheme and presented the first experimental demonstration of acoustic illusion, by using anisotropic metamaterials to manipulate the acoustic field near boundaries of arbitrary curved geometry. Numerical simulations and experimental results show that in the presence of an illusion cloak, any object ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep01427

    authors: Kan W,Liang B,Zhu X,Li R,Zou X,Wu H,Yang J,Cheng J

    更新日期:2013-01-01 00:00:00

  • Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training.

    abstract::Regular exercise elicits advantageous metabolic adaptations in skeletal muscle, such as improved insulin sensitivity. However, the underpinning molecular mechanisms and the effect of diet on muscle exercise training benefits are unclear. We therefore characterized the skeletal muscle proteome following exercise traini...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-28540-5

    authors: Kleinert M,Parker BL,Jensen TE,Raun SH,Pham P,Han X,James DE,Richter EA,Sylow L

    更新日期:2018-07-16 00:00:00

  • Target-distractor competition cannot be resolved across a saccade.

    abstract::When a distractor is presented in close spatial proximity to a target, a saccade tends to land in between the two objects rather than on the target. This robust phenomenon (also referred to as the global effect) is thought to reflect unresolved competition between target and distractor. It is unclear whether this land...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-34120-4

    authors: Arkesteijn K,Smeets JBJ,Donk M,Belopolsky AV

    更新日期:2018-10-24 00:00:00

  • Inducible Antibacterial Activity in the Bacillales by Triphenyl Tetrazolium Chloride.

    abstract::The world is in the midst of an antimicrobial resistance crisis, driving a need to discover novel antibiotic substances. Using chemical cues as inducers to unveil a microorganism's full metabolic potential is considered a successful strategy. To this end, we investigated an inducible antagonistic behavior in multiple ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-62236-z

    authors: Sierra-Zapata L,Álvarez JC,Romero-Tabarez M,Silby MW,Traxler MF,Behie SW,Pessotti RC,Villegas-Escobar V

    更新日期:2020-03-27 00:00:00

  • Remote control of resistive switching in TiO2 based resistive random access memory device.

    abstract::We report on the magnetic field control of a bipolar resistive switching in Ag/TiO2/FTO based resistive random access memory device through I-V characteristics. Essentially, in the presence of magnetic field and in the low resistance state, an abrupt change in the resistance of the device demands higher voltage, hinti...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17607-4

    authors: Sahu DP,Jammalamadaka SN

    更新日期:2017-12-08 00:00:00

  • HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system.

    abstract::Despite the effectiveness of combined anti-retroviral therapy, human immunodeficiency virus (HIV) infected-patients frequently report diarrhea and neuropsychological deficits. It is claimed that the viral HIV-1 Trans activating factor (HIV-1 Tat) protein is responsible for both diarrhea and neurotoxic effects, but the...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05245-9

    authors: Esposito G,Capoccia E,Gigli S,Pesce M,Bruzzese E,D'Alessandro A,Cirillo C,di Cerbo A,Cuomo R,Seguella L,Steardo L,Sarnelli G

    更新日期:2017-08-10 00:00:00

  • Early antiretroviral therapy on reducing HIV transmission in China: strengths, weaknesses and next focus of the program.

    abstract::Early antiretroviral therapy (ART) initiation is a recommended public health approach for the prevention of HIV-1 transmission. In this cohort study, we included 13132 serodiscordant couples. ART was initiated for patients with CD4+ T cell counts less than 200 cells/uL, 350 cells/uL, and 500 cells/uL respectively. Thi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-21791-2

    authors: Liu P,Tang Z,Lan G,Zhu Q,Chen H,You Y,Yang X,Liang S,Chen Y,Xing H,Liao L,Feng Y,Shen Z,Ruan Y,Shao Y

    更新日期:2018-02-21 00:00:00

  • Pathway and kinetics of malachite green biodegradation by Pseudomonas veronii.

    abstract::Malachite green is a common environmental pollutant that poses a great threat to non-target organisms, including humans. This study reports the characterization of a bacterial strain, Pseudomonas veronii JW3-6, which was isolated from a malachite green enrichment culture. This strain degraded malachite green efficient...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-61442-z

    authors: Song J,Han G,Wang Y,Jiang X,Zhao D,Li M,Yang Z,Ma Q,Parales RE,Ruan Z,Mu Y

    更新日期:2020-03-11 00:00:00

  • Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research.

    abstract::Although re-sequencing of gene panels and mRNA expression profiling are now firmly established in clinical laboratories, in-depth proteome analysis has remained a niche technology, better suited for studying model systems rather than challenging materials such as clinical trial samples. To address this limitation, we ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep34949

    authors: Hughes CS,McConechy MK,Cochrane DR,Nazeran T,Karnezis AN,Huntsman DG,Morin GB

    更新日期:2016-10-07 00:00:00

  • Gene set of chemosensory receptors in the polyembryonic endoparasitoid Macrocentrus cingulum.

    abstract::Insects are extremely successful animals whose odor perception is very prominent due to their sophisticated olfactory system. The main chemosensory organ, antennae play a critical role in detecting odor in ambient environment before initiating appropriate behavioral responses. The antennal chemosensory receptor genes ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24078

    authors: Ahmed T,Zhang T,Wang Z,He K,Bai S

    更新日期:2016-04-19 00:00:00

  • The coelacanth rostral organ is a unique low-resolution electro-detector that facilitates the feeding strike.

    abstract::The cartilaginous and non-neopterygian bony fishes have an electric sense typically comprised of hundreds or thousands of sensory canals distributed in broad clusters over the head. This morphology facilitates neural encoding of local electric field intensity, orientation, and polarity, used for determining the positi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep08962

    authors: Berquist RM,Galinsky VL,Kajiura SM,Frank LR

    更新日期:2015-03-11 00:00:00

  • Hidden parasite diversity in a European freshwater system.

    abstract::Parasites comprise a huge part of the biodiversity on earth. However, on a local scale, not much is known about their diversity and community structure. Here, we assess the diversity of larval trematode communities in an interconnected freshwater system of the River Ruhr in Germany and analyse how the parasites are sp...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59548-5

    authors: Selbach C,Soldánová M,Feld CK,Kostadinova A,Sures B

    更新日期:2020-02-14 00:00:00

  • Five-month-old infants detect affiliation in colaughter.

    abstract::Colaughter-simultaneous laughter between two or more individuals-allows listeners across different cultures and languages to quickly evaluate affiliation within a social group. We examined whether infants are sensitive to acoustic information in colaughter that indicates affiliation, specifically whether they can diff...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-38954-4

    authors: Vouloumanos A,Bryant GA

    更新日期:2019-03-11 00:00:00

  • New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.

    abstract::Roquins are a family of highly conserved RNA-binding proteins that also contain a RING-type E3 ubiquitin ligase domain. They repress constitutive decay elements containing mRNAs and play a critical role in RNA homeostasis and immunological self-tolerance. Here we present the crystal structures of the RNA-binding regio...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep15660

    authors: Zhang Q,Fan L,Hou F,Dong A,Wang YX,Tong Y

    更新日期:2015-10-22 00:00:00

  • Searching for signatures across microbial communities: Metagenomic analysis of soil samples from mangrove and other ecosystems.

    abstract::In this study, we categorize the microbial community in mangrove sediment samples from four different locations within a vast mangrove system in Kerala, India. We compared this data to other samples taken from the other known mangrove data, a tropical rainforest, and ocean sediment. An examination of the microbial com...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-09254-6

    authors: Imchen M,Kumavath R,Barh D,Azevedo V,Ghosh P,Viana M,Wattam AR

    更新日期:2017-08-18 00:00:00

  • A compact silicon grating coupler based on hollow tapered spot-size converter.

    abstract::A new compact silicon grating coupler enabling fibre-to-chip light coupling at a minimized taper length is proposed. The proposed coupler, which incorporates a hollow tapered waveguide, converts the spot-size of optical modes from micro- to nano-scales by reducing the lateral dimension from 15 µm to 300 nm at a length...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-20875-3

    authors: Asaduzzaman M,Bakaul M,Skafidas E,Khandokar MRH

    更新日期:2018-02-07 00:00:00

  • Liberalizing the killing of endangered wolves was associated with more disappearances of collared individuals in Wisconsin, USA.

    abstract::Although poaching (illegal killing) is an important cause of death for large carnivores globally, the effect of lethal management policies on poaching is unknown for many populations. Two opposing hypotheses have been proposed: liberalizing killing may decrease poaching incidence ('tolerance hunting') or increase it (...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-70837-x

    authors: Santiago-Ávila FJ,Chappell RJ,Treves A

    更新日期:2020-08-17 00:00:00

  • MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression.

    abstract::Precise mitotic spindle orientation is essential for both cell fate and tissue organization while defects in this process are associated with tumorigenesis and other diseases. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral microtubules to position...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-24682-8

    authors: Vodicska B,Cerikan B,Schiebel E,Hoffmann I

    更新日期:2018-04-20 00:00:00

  • Enhanced transparency, mechanical durability, and antibacterial activity of zinc nanoparticles on glass substrate.

    abstract::Homogeneously distributed zinc nanoparticles (NPs) on the glass substrate were investigated for the transmittance, mechanical durability, and antibacterial effect. The buffered Ti NPs between Zn NPs and glass substrate were studied for an enhancement of the transmittance and mechanical endurance. The Ti NPs buffered Z...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep06271

    authors: Choi HJ,Choi JS,Park BJ,Eom JH,Heo SY,Jung MW,An KS,Yoon SG

    更新日期:2014-09-03 00:00:00

  • An efficient micropropagation protocol for an endangered ornamental tree species (Magnolia sirindhorniae Noot. & Chalermglin) and assessment of genetic uniformity through DNA markers.

    abstract::Magnolia sirindhorniae Noot. & Chalermglin is an endangered species with high ornamental and commercial value that needs to be urgently protected and judiciously commercialized. In this study, a protocol for efficient regeneration of this species is standardized. The lateral buds of the M. sirindhorniae plant were use...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-46050-w

    authors: Cui Y,Deng Y,Zheng K,Hu X,Zhu M,Deng X,Xi R

    更新日期:2019-07-03 00:00:00

  • Asymmetric paralog evolution between the "cryptic" gene Bmp16 and its well-studied sister genes Bmp2 and Bmp4.

    abstract::The vertebrate gene repertoire is characterized by "cryptic" genes whose identification has been hampered by their absence from the genomes of well-studied species. One example is the Bmp16 gene, a paralog of the developmental key genes Bmp2 and -4. We focus on the Bmp2/4/16 group of genes to study the evolutionary dy...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-40055-1

    authors: Feiner N,Motone F,Meyer A,Kuraku S

    更新日期:2019-02-28 00:00:00

  • The depleted mineralization of the fungicide chlorothalonil derived from loss in soil microbial diversity.

    abstract::There are lack of studies regarding the effects of microbial diversity on specific soil functions, such as pesticides degradation. This study evaluated the role of bacterial community diversity and biochar on chlorothalonil (CTN) degradation, using 'dilution to extinction' approach, PCR-DGGE/16S rRNA gene technique, a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-14803-0

    authors: de Souza AJ,de Andrade PAM,de Araújo Pereira AP,Andreote FD,Tornisielo VL,Regitano JB

    更新日期:2017-11-07 00:00:00

  • Electron beam-assisted healing of nanopores in magnesium alloys.

    abstract::Nanopore-based sensing has emerged as a promising candidate for affordable and powerful DNA sequencing technologies. Herein, we demonstrate that nanopores can be successfully fabricated in Mg alloys via focused electron beam (e-beam) technology. Employing in situ high-resolution transmission electron microscopy techni...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep01920

    authors: Zheng H,Liu Y,Cao F,Wu S,Jia S,Cao A,Zhao D,Wang J

    更新日期:2013-01-01 00:00:00

  • Deletion of biosynthetic genes, specific SNP patterns and differences in transcript accumulation cause variation in hydroxynitrile glucoside content in barley cultivars.

    abstract::Barley (Hordeum vulgare L.) produces five leucine-derived hydroxynitrile glucosides, potentially involved in alleviating pathogen and environmental stresses. These compounds include the cyanogenic glucoside epiheterodendrin. The biosynthetic genes are clustered. Total hydroxynitrile glucoside contents were previously ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-41884-w

    authors: Ehlert M,Jagd LM,Braumann I,Dockter C,Crocoll C,Motawia MS,Møller BL,Lyngkjær MF

    更新日期:2019-04-05 00:00:00

  • Integration of fish culture and poultry rearing in transplanted rice for nutritional security in smallholder farms.

    abstract::Agriculture provides livelihood for 65% of Nepal's population contributing for 27% of its GDP. Smallholder farms constitute 60% of farming segment. Distress farming, with inadequate minimum support price, subsidies and inadequate revenue generation force 29% of the general population to be malnourished. Farming system...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-67657-4

    authors: Ramanathan K,Sangeeviraman V,Chandrahasan P,Chaudhary BN,Ramachandra SS

    更新日期:2020-06-29 00:00:00