Abstract：
:Type-III secreted effectors (T3Es) play critical roles during bacterial pathogenesis in plants. Plant recognition of certain T3Es can trigger defence, often accompanied by macroscopic cell death, termed the hypersensitive response (HR). Economically important species of kiwifruit are susceptible to Pseudomonas syringae pv. actinidiae (Psa), the causal agent of kiwifruit bacterial canker. Although Psa is non-pathogenic in Arabidopsis thaliana, we observed that a T3E, HopZ5 that is unique to a global outbreak clade of Psa, triggers HR and defence in Arabidopsis accession Ct-1. Ws-2 and Col-0 accessions are unable to produce an HR in response to Pseudomonas-delivered HopZ5. While Ws-2 is susceptible to virulent bacterial strain Pseudomonas syringae pv. tomato DC3000 carrying HopZ5, Col-0 is resistant despite the lack of an HR. We show that HopZ5, like other members of the YopJ superfamily of acetyltransferases that it belongs to, autoacetylates lysine residues. Through comparisons to other family members, we identified an acetyltransferase catalytic activity and demonstrate its requirement for triggering defence in Arabidopsis and Nicotiana species. Collectively, data herein indicate that HopZ5 is a plasma membrane-localized acetyltransferase with autoacetylation activity required for avirulence.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Jayaraman J,Choi S,Prokchorchik M,Choi DS,Spiandore A,Rikkerink EH,Templeton MD,Segonzac C,Sohn KHdoi
10.1038/s41598-017-03704-xsubject
Has Abstractpub_date
2017-06-15 00:00:00pages
3557issue
1issn
2045-2322pii
10.1038/s41598-017-03704-xjournal_volume
7pub_type
杂志文章abstract：:Sulfonylureas are commonly used to treat type 2 diabetes mellitus. Despite awareness of their effects on cardiac physiology, a knowledge gap exists regarding their effects on cardiovascular events in real-world populations. Prior studies reported sulfonylurea-associated cardiovascular death but not serious arrhythmoge...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66668-5
更新日期：2020-06-22 00:00:00
abstract：:SiO2 is the most significantly used insulator layer in semiconductor devices. Its functionality was recently extended to resistance switching random access memory, where the defective SiO2 played an active role as the resistance switching (RS) layer. In this report, the bias-polarity-dependent RS behaviours in the top...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22216
更新日期：2016-02-26 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-35364-w
更新日期：2018-11-16 00:00:00
abstract：:Objectives were to evaluate the role of canonical WNT signaling in development of the preimplantation embryo. Signaling was activated with 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine (AMBMP) and inhibited with Dickkopf-related protein 1 (DKK1). Treatment of bovine embryos with AMBMP at da...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01266
更新日期：2013-01-01 00:00:00
abstract：:Central visual field (CVF) loss has been linked to poorer vision-related quality of life in eyes with open-angle glaucoma (OAG) and can occur even in early-stage OAG eyes. The present study investigated whether the detection of choroidal microvasculature dropout (CMvD) during follow-up, which may be a sign of perfusio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44942-5
更新日期：2019-06-12 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-57826-w
更新日期：2020-01-15 00:00:00
abstract：:Glucocorticoid receptor (GR) is a hormone-activated transcription regulatory protein involved in metabolism as well as adrenocortical responses to psychosocial stress. Ligand-activated GR localizes to the nucleus, where GR homodimers regulate gene transcription via direct binding to glucocorticoid response elements (G...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25393-w
更新日期：2018-05-10 00:00:00
abstract：:The lack of vaccines and antiviral treatment, along with the increasing number of cases of Zika virus (ZIKV) and Chikungunya virus (CHIKV) infections, emphasize the need for searching for new therapeutic strategies. In this context, the marine brown seaweed Canistrocarpus cervicornis has been proved to hold great anti...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65357-7
更新日期：2020-05-19 00:00:00
abstract：:Complex systems, arising in many contexts in the computer, life, social, and physical sciences, have not shared a generally-accepted complexity measure playing a fundamental role as the Shannon entropy H in statistical mechanics. Superficially-conflicting criteria of complexity measurement, i.e. complexity-randomness ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01585
更新日期：2013-01-01 00:00:00
abstract：:Facial beauty and moral beauty have been suggested to be two significant forms of social aesthetics. However, it remains unknown the extent to which there are neural underpinnings of the integration of these two forms of beauty. In the present study, participants were asked to make general aesthetic judgments of facia...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38553-3
更新日期：2019-02-13 00:00:00
abstract：:The oxidative stress regulator Spx is ubiquitously found among Gram-positive bacteria. Previously, we reported identification of two Spx proteins in Streptococcus mutans - SpxA1 was the primary activator of oxidative stress genes whereas SpxA2 served a backup role. Here, we used RNA sequencing to uncover the scope of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16367-5
更新日期：2017-11-22 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-63941-5
更新日期：2020-05-18 00:00:00
abstract：:Control of genetic regulatory networks is challenging to define and quantify. Previous control centrality metrics, which aim to capture the ability of individual nodes to control the system, have been found to suffer from plausibility and applicability problems. Here we present a new approach to control centrality bas...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09746
更新日期：2015-06-11 00:00:00
abstract：:Circulating miRNAs have attracted attention as serum biomarkers for several diseases. In this study, we aimed to evaluate the diagnostic value of circulating miRNA-21 (miR-21) as a novel biomarker for elderly patients with type 2 cardiorenal syndrome (CRS-2). A total of 157 elderly patients with chronic heart failure ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61836-z
更新日期：2020-03-17 00:00:00
abstract：:Intravitreal Conbercept (IVC) is the latest applied and effective treatment for the management of retinopathy of prematurity (ROP). However, conbercept escapes from the vitreous into the general circulation and reduce systemic VEGF concentrations. Thus, there are concerns about systemic complications, in these prematu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28987-6
更新日期：2018-07-16 00:00:00
abstract：:We demonstrated an abnormal double-peak (annular shaped) energy deposition through dual-wavelength synthesis of the fundamental frequency (ω) and the second-harmonic frequency (2ω) of a femtosecond (fs) Ti:sapphire laser. The annular shaped distribution of the dual-wavelength fs laser was confirmed through real beam s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16374-6
更新日期：2017-12-11 00:00:00
abstract：:Cellvibrio mixtus strain J3-8 is a gram-negative, xylanase-producing aerobic soil bacterium isolated from giant snails in Singapore. It is able to produce up to 10.1 U ml(-1) of xylanase, which is comparable to xylanase production from known bacterial and fungal strains. Genome sequence analysis of strain J3-8 reveals...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10521
更新日期：2015-05-21 00:00:00
abstract：:We have developed an optimized protocol for plasma targeted mRNA sequencing in our previous study. Here, we performed plasma targeted mRNA sequencing for 40 colorectal adenoma patients and 39 colonoscopy-proven normal controls in order to find potential circulating mRNA markers for colorectal adenoma. Results showed t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49445-x
更新日期：2019-09-10 00:00:00
abstract：:No licensed human vaccines are currently available against leishmaniasis. Several anti-leishmanial vaccines are currently undergoing testing, including genetically modified live-attenuated parasite vaccines. Studies with live attenuated Leishmania vaccines such as centrin deleted Leishmania donovani parasites (LdCen -...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05088-4
更新日期：2017-07-05 00:00:00
abstract：:Patients with chronic kidney disease have a greater risk of cognitive impairment. Cerebral uremic solute accumulation causes uremic encephalopathy; however, the association of protein-bound uremic toxins on cognitive function remains unclear. The present study aimed to investigate the association of two protein-bound ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-57004-7
更新日期：2019-12-31 00:00:00
abstract：:In Taiwan, beginning in 2013, the 13-valent pneumococcal conjugate vaccine (PCV13) was provided free of charge to children 2-5 years of age. In 2014, this was extended to children 1-5 years old. During 2012-2014, 953 cases of culture-confirmed pneumococcal disease (CCPD), including 104 invasive pneumococcal disease (I...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep15843
更新日期：2015-11-02 00:00:00
abstract：:The binding of metal ions at the interface of protein complexes presents a unique and poorly understood mechanism of molecular assembly. A remarkable example is the Rad50 zinc hook domain, which is highly conserved and facilitates the Zn2+-mediated homodimerization of Rad50 proteins. Here, we present a detailed analys...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36346
更新日期：2016-11-03 00:00:00
abstract：:The fungal communities of different soil compartments in mangrove ecosystem are poorly studied. We sequenced the internal transcribed spacer (ITS) regions to characterize the fungal communities in Avicennia marina root-associated soils (rhizosphere and pneumatophore) and bulk soil compartments. The rhizosphere but not...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09281-3
更新日期：2017-08-17 00:00:00
abstract：:Resolving the immunogenicity of cells derived from induced pluripotent stem cells (iPSCs) remains an important challenge for cell transplant strategies that use banked allogeneic cells. Thus, we evaluated the immunogenicity of mouse fetal neural stem/progenitor cells (fetus-NSPCs) and iPSC-derived neural stem/progenit...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13522-w
更新日期：2017-10-11 00:00:00
abstract：:It is frequently assumed that in the limit of vanishing cooling rate, the glass transition phenomenon becomes a thermodynamic transition at a temperature TK. However, with any finite cooling rate, the system falls out of equilibrium at temperatures near Tg(>TK), implying that the very existence of the putative thermod...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12577
更新日期：2015-07-24 00:00:00
abstract：:Knowledge of the structure-property-function relationship of humic substances (HSs) is key for understanding their role in soil. Despite progress, studies on this topic are still under discussion. We analyzed 37 humic fractions with respect to their isotopic composition, structural characteristics, and properties resp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20798
更新日期：2016-02-10 00:00:00
abstract：:Studies of morphological integration and modularity, and of anatomical complexity in human evolution typically focus on skeletal tissues. Here we provide the first network analysis of the musculoskeletal anatomy of both the fore- and hindlimbs of the two species of chimpanzee and humans. Contra long-accepted ideas, ne...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25262-6
更新日期：2018-05-02 00:00:00
abstract：:The Japanese macaque (Macaca fuscata) exhibits a species-specific communication sound called the "coo call" to locate group members and maintain within-group contact. Monkeys have been demonstrated to be capable of discriminating between individuals based only on their voices, but there is still debate regarding how t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep32042
更新日期：2016-08-23 00:00:00
abstract：:The mammalian retina encodes the visual world in action potentials generated by 20-50 functionally and anatomically-distinct types of retinal ganglion cell (RGC). Individual RGC types receive synaptic input from distinct presynaptic circuits; therefore, their responsiveness to specific features in the visual scene ari...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45048-8
更新日期：2019-06-18 00:00:00
abstract：:Bursaphelenchus xylophilus is a quarantined migratory endoparasite known to cause severe economic losses in pine forest ecosystems. The study presents the nematicidal effects of halogenated indoles on B. xylophilus and their action mechanisms. 5-Iodoindole and abamectin (positive control) at low concentration (10 µg/m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07074-2
更新日期：2017-07-28 00:00:00
