Acoustic tweezing cytometry for live-cell subcellular modulation of intracellular cytoskeleton contractility.

abstract：:A topical medication combining calcipotriol (Cal) and betamethasone dipropionate (BDP) has proven effective in a number of randomized controlled trials performed in patients with psoriasis, but its mechanism of action has not been fully elucidated. We investigated whether the combination of Cal and BDP (Cal/BDP) in th...

journal_title：Scientific reports

authors： Satake K,Amano T,Okamoto T

更新日期：2019-11-08 00:00:00

abstract：:The CoCrMo matrix composites with nano-TiO2 particle (2 wt.%, 4 wt.% and 6 wt.%) were fabricated by using a powder metallurgy technique (P/M), and the nano-TiO2 content was optimized in matrix. The microstructures, mechanical and high-temperature tribological properties of the synthesized composites were systematicall...

journal_title：Scientific reports

authors： Cui G,Liu Y,Li S,Liu H,Gao G,Kou Z

更新日期：2020-04-22 00:00:00

abstract：:Two-dimensional (2D) porous carbon AC-SPN-3 possessing of amazing high micropore volume ratio of 83% and large surface area of about 1069 m(2) g(-1) is high-yield obtained by pyrolysis of natural waste Pistachio nutshells with KOH activation. The AC-SPN-3 has a curved 2D lamellar morphology with the thickness of each ...

journal_title：Scientific reports

authors： Xu J,Gao Q,Zhang Y,Tan Y,Tian W,Zhu L,Jiang L

更新日期：2014-07-02 00:00:00

abstract：:The remineralization mechanism in dental caries lesions is not completely understood. This study reports on ultrastructural and chemical changes observed within arrested caries lesions. Carious human teeth were observed using scanning electron microscopy (SEM) and focused-ion-beam (FIB)-SEM. The crystals detected in t...

journal_title：Scientific reports

authors： Yoshihara K,Nagaoka N,Nakamura A,Hara T,Hayakawa S,Yoshida Y,Van Meerbeek B

更新日期：2020-03-09 00:00:00

abstract：:Surface-enhanced Raman scattering (SERS) can significantly boost the inherently weak Raman scattering signal and provide detailed structural information and binding nature of the molecules on the surface. Despite the long history of this technology, SERS has yet to become a sophisticated analytical tool in practical a...

journal_title：Scientific reports

authors： Liu X,Wang J,Wu Y,Fan T,Xu Y,Tang L,Ying Y

更新日期：2015-11-30 00:00:00

abstract：:Schizophrenia is a common neuropsychiatric disorder with a lifetime risk of 1%. Accumulation of common polygenic variations has been found to be an important risk factor. Recent studies showed a role for the enrichment of minor alleles (MAs) of SNPs in complex diseases such as Parkinson's disease. Here we similarly st...

journal_title：Scientific reports

authors： He P,Lei X,Yuan D,Zhu Z,Huang S

更新日期：2017-09-15 00:00:00

abstract：:Dissolved organic carbon (DOC) concentrations and water colour are increasing in many inland waters across northern Europe and northeastern North America. This inland-water "browning" has profound physical, chemical and biological repercussions for aquatic ecosystems affecting water quality, biological community struc...

journal_title：Scientific reports

authors： Meyer-Jacob C,Michelutti N,Paterson AM,Cumming BF,Keller WB,Smol JP

更新日期：2019-11-13 00:00:00

abstract：:Lophatheri Herba (LH), dried leaf of Lophatherum gracile Brongn, has long been used to reduce thirst and treat fever and inflammation in Chinese medicine. Recent studies have shown that LH has anti-viral, anti-bacterial, anti-cancer, anti-oxidant, diuretic, and hyperglycemic properties. However, the effects of an etha...

journal_title：Scientific reports

authors： Kim A,Im M,Gu MJ,Ma JY

更新日期：2016-11-03 00:00:00

abstract：:Symblepharon due to chemical burns affects ocular surface health, and there are currently no satisfactory treatments. To improve our understanding of symblepharon, an appropriate animal model is urgently needed. We established a rabbit model of superior conjunctival sac alkaline burn to evaluate symblepharon severity....

journal_title：Scientific reports

authors： Kang Y,Li S,Liu C,Liu M,Shi S,Xu M,He J,Zhang T

更新日期：2019-09-25 00:00:00

abstract：:We have studied differentially regulated nuclear proteome of the clinical tissue specimens of glioblastoma (GBM, WHO Grade IV) and lower grades of gliomas (Grade II and III) using high resolution mass spectrometry- based quantitative proteomics approach. The results showed altered expression of many regulatory protein...

journal_title：Scientific reports

authors： Gupta MK,Polisetty RV,Sharma R,Ganesh RA,Gowda H,Purohit AK,Ankathi P,Prasad K,Mariswamappa K,Lakshmikantha A,Uppin MS,Sundaram C,Gautam P,Sirdeshmukh R

更新日期：2019-07-29 00:00:00

abstract：:Visceral adiposity is a risk factor for cardiovascular disorders, type 2 diabetes mellitus (T2D) and associated metabolic diseases. Sub-cutaneous fat is believed to be intrinsically different from visceral fat. To understand molecular mechanisms involved in metabolic advantages of fat transplantation, we studied a rat...

journal_title：Scientific reports

authors： Satoor SN,Puranik AS,Kumar S,Williams MD,Ghale M,Rahalkar A,Karandikar MS,Shouche Y,Patole M,Bhonde R,Yajnik CS,Hardikar AA

更新日期：2011-01-01 00:00:00

abstract：:In the Ultimatum Game, two players are offered a chance to win a pie. The proposer suggests how to split the pie. The responder can either accept or reject the deal. If an agreement is not reached, neither player gets anything. Both game theory and evolutionary game theory predict the rational solution that the propos...

journal_title：Scientific reports

authors： Wang X,Chen X,Wang L

更新日期：2014-04-01 00:00:00

abstract：:Dengue virus (DENV) is currently the most prevalent mosquito-borne viral pathogen. DENVs naturally exist as highly heterogeneous populations. Even though the descriptions on DENV diversity are plentiful, only a few studies have narrated the dynamics of intra-epidemic virus diversity at a fine scale. Such accounts are ...

journal_title：Scientific reports

authors： Hapuarachchi HC,Koo C,Kek R,Xu H,Lai YL,Liu L,Kok SY,Shi Y,Chuen RL,Lee KS,Maurer-Stroh S,Ng LC

更新日期：2016-03-04 00:00:00

abstract：:Rassf1A/5 tumor suppressors serve as adaptor proteins possessing a modular architecture with the C-terminal consisting of a coiled-coil SARAH (Salvador-Rassf-Hippo) domain and the central portion being composed of Ras associated (RA) domain. Here, we investigate the effect of Rassf effectors on Mst1 function by mappin...

journal_title：Scientific reports

authors： Bitra A,Sistla S,Mariam J,Malvi H,Anand R

更新日期：2017-03-22 00:00:00

abstract：:Silicon nanocrystals offer huge advantages compared to other semi-conductor quantum dots as they are made from an abundant, non-toxic material and are compatible with silicon devices. Besides, among a wealth of extraordinary properties ranging from catalysis to nanomedicine, metal nanoparticles are known to increase t...

journal_title：Scientific reports

authors： Goffard J,Gérard D,Miska P,Baudrion AL,Deturche R,Plain J

更新日期：2013-01-01 00:00:00

abstract：:Stroke is one of the main causes of human disabilities. Experimental observations indicate that several mechanisms are activated during the recovery of functional activity after a stroke. Here we unveil how the brain recovers by explaining the role played by three mechanisms: Plastic adaptation, hyperexcitability and ...

journal_title：Scientific reports

authors： Berger D,Varriale E,van Kessenich LM,Herrmann HJ,de Arcangelis L

更新日期：2019-11-01 00:00:00

abstract：:We estimated the prevalence of anemia among school children and investigated factors associated with this problem in Kuwait. A cross-sectional study was conducted on 1415 adolescents randomly selected from middle schools in Kuwait. Hemoglobin, iron, ferritin, folate and vitamin B12, in addition to many other laborator...

journal_title：Scientific reports

authors： Shaban L,Al-Taiar A,Rahman A,Al-Sabah R,Mojiminiyi O

更新日期：2020-04-03 00:00:00

abstract：:The mammalian central nervous system (CNS) contains various types of neurons with different neuronal functions. In contrast to established roles of cell type-specific transcription factors on neuronal specification and maintenance, whether ubiquitous transcription factors have conserved or differential neuronal functi...

journal_title：Scientific reports

authors： Yamanaka T,Tosaki A,Miyazaki H,Kurosawa M,Koike M,Uchiyama Y,Maity SN,Misawa H,Takahashi R,Shimogori T,Hattori N,Nukina N

更新日期：2016-09-30 00:00:00

abstract：:IL-37 is a novel pro-angiogenic cytokine that potently promotes endothelial cell activation and pathological angiogenesis in our previous study, but the mechanisms behind the pro-angiogenic effect of IL-37 are less well understood. Extending our observations, we found that TGF-β interacts with IL-37, and potently enha...

journal_title：Scientific reports

authors： Zhao M,Hu Y,Jin J,Yu Y,Zhang S,Cao J,Zhai Y,Wei R,Shou J,Cai W,Liu S,Yang X,Xu GT,Yang J,Corry DB,Su SB,Liu X,Yang T

更新日期：2017-07-21 00:00:00

abstract：:Recent successes in malaria control have been largely attributable to the deployment of insecticide-based vector control tools such as bed nets and indoor residual spraying. Pyrethroid-treated bed nets are acutely neurotoxic to mosquitoes, inducing symptoms such as loss of coordination, paralysis, and violent spasms. ...

journal_title：Scientific reports

authors： Isaacs AT,Lynd A,Donnelly MJ

更新日期：2017-04-25 00:00:00

abstract：:Interfacial charge transfer from photoexcited ruthenium-based N3 dye molecules into ZnO thin films received controversial interpretations. To identify the physical origin for the delayed electron transfer in ZnO compared to TiO2, we probe directly the electronic structure at both dye-semiconductor interfaces by applyi...

journal_title：Scientific reports

authors： Borgwardt M,Wilke M,Kampen T,Mähl S,Xiao M,Spiccia L,Lange KM,Kiyan IY,Aziz EF

更新日期：2016-04-13 00:00:00

abstract：:Systems of closely-spaced resonators can be strongly coupled by interactions mediated by scattered electromagnetic fields. In large systems the resulting response has been shown to be more sensitive to these collective interactions than to the detailed structure of individual resonators. Attempts to describe such syst...

journal_title：Scientific reports

authors： Watson DW,Jenkins SD,Fedotov VA,Ruostekoski J

更新日期：2019-04-05 00:00:00

abstract：:Weight regain is one of the most common problems in the long-term after bariatric surgery. It is unknown if high-intensity exercise programs applied in late phases of post-surgical follow-up could counteract this trend. After a 3-year follow-up, 21 patients underwent sleeve gastrectomy were randomized into an exercise...

journal_title：Scientific reports

authors： Marc-Hernández A,Ruiz-Tovar J,Aracil A,Guillén S,Moya-Ramón M

更新日期：2020-02-20 00:00:00

abstract：:The selective destruction of large-scale brain networks by pathogenic protein spread is a ubiquitous theme in neurodegenerative disease. Characterising the circuit architecture of these diseases could illuminate both their pathophysiology and the computational architecture of the cognitive processes they target. Howev...

journal_title：Scientific reports

authors： Benhamou E,Marshall CR,Russell LL,Hardy CJD,Bond RL,Sivasathiaseelan H,Greaves CV,Friston KJ,Rohrer JD,Warren JD,Razi A

更新日期：2020-10-01 00:00:00

abstract：:Pitch is a complex hearing phenomenon that results from elicited and self-generated cochlear vibrations. Read-off vibrational information is relayed higher up the auditory pathway, where it is then condensed into pitch sensation. How this can adequately be described in terms of physics has largely remained an open que...

journal_title：Scientific reports

authors： Martignoli S,Gomez F,Stoop R

更新日期：2013-01-01 00:00:00

abstract：:Cu removal by a novel multi-amines decorated resin (PAMD) from wastewater in the absence or presence of citric acid (CA) was examined. Adsorption capacity of Cu onto PAMD markedly increased by 186% to 5.07 mmol/g in the presence of CA, up to 7 times of that onto four commercial resins under the same conditions. Preloa...

journal_title：Scientific reports

authors： Ling C,Liu F,Pei Z,Zhang X,Wei M,Zhang Y,Zheng L,Zhang J,Li A,Xing B

更新日期：2015-05-12 00:00:00

abstract：:In the human visual system, different attributes of an object, such as shape and color, are separately processed in different modules and then integrated to elicit a specific response. In this process, different attributes are thought to be temporarily "bound" together by focusing attention on the object; however, how...

journal_title：Scientific reports

authors： Ishizaki T,Morita H,Morita M

更新日期：2015-03-12 00:00:00

abstract：:Support from human genetics increases the probability of success in drug development. However, few examples exist of successful genomically-driven drug repositioning. Given that a Mendelian form of severe enterocolitis is due to up-regulation of the interleukin-18 (IL18) signaling pathway, and pharmacologic inhibition...

journal_title：Scientific reports

authors： Mokry LE,Zhou S,Guo C,Scott RA,Devey L,Langenberg C,Wareham N,Waterworth D,Cardon L,Sanseau P,Davey Smith G,Richards JB

更新日期：2019-06-28 00:00:00

abstract：:Plasmonic photothermal therapy (PPTT) using plasmonic nanoparticles as efficient photoabsorbing agents has been proposed previously. One critical step in PPTT is to effectively deliver gold nanoparticles into the cells. This study demonstrates that the delivery of gold nanorods (AuNRs) can be greatly enhanced by combi...

journal_title：Scientific reports

authors： Wang YH,Chen SP,Liao AH,Yang YC,Lee CR,Wu CH,Wu PC,Liu TM,Wang CR,Li PC

更新日期：2014-07-14 00:00:00

abstract：:The natural bacterial diversity is regarded as a treasure trove for natural products. However, accessing complex cell mixtures derived from environmental samples in standardized high-throughput screenings is challenging. Here, we present a droplet-based microfluidic platform for ultrahigh-throughput screenings able to...

journal_title：Scientific reports

authors： Mahler L,Wink K,Beulig RJ,Scherlach K,Tovar M,Zang E,Martin K,Hertweck C,Belder D,Roth M

更新日期：2018-08-30 00:00:00