Abstract:
:Recent successes in malaria control have been largely attributable to the deployment of insecticide-based vector control tools such as bed nets and indoor residual spraying. Pyrethroid-treated bed nets are acutely neurotoxic to mosquitoes, inducing symptoms such as loss of coordination, paralysis, and violent spasms. One result of pyrethroid exposure often seen in laboratory tests is mosquito leg loss, a condition that has thus far been assumed to equate to mortality, as females are not expected to blood feed. However, whilst limb loss is unlikely to be adaptive, females with missing limbs may play a role in the propagation of both their species and pathogens. To test the hypothesis that leg loss inhibits mosquitoes from biting and reproducing, mosquitoes with one, two, or six legs were evaluated for their success in feeding upon a human. These experiments demonstrated that insecticide-induced leg loss had no significant effect upon blood feeding or egg laying success. We conclude that studies of pyrethroid efficacy should not discount mosquitoes that survive insecticide exposure with fewer than six legs, as they may still be capable of biting humans, reproducing, and contributing to malaria transmission.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Isaacs AT,Lynd A,Donnelly MJdoi
10.1038/srep46674subject
Has Abstractpub_date
2017-04-25 00:00:00pages
46674issn
2045-2322pii
srep46674journal_volume
7pub_type
杂志文章abstract::Maize rough dwarf virus (MRDV) is one of the main yield-limiting factors of maize in the Mediterranean. However, knowledge about the interactions between the agroecosystem and the virus-vector-host relationship continues to be limited. We used multi-model inference to test a landscape-scale approach together with vari...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79994-5
更新日期:2021-01-13 00:00:00
abstract::Cardiac contractility is enhanced by phosphorylation of myosin light chain 2 (MLC2) by cardiac-specific MLC kinase (cMLCK), located at the neck region of myosin heavy chain. In normal mouse and human hearts, the level of phosphorylation is maintained relatively constant, at around 30-40% of total MLC2, likely by well-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48884-w
更新日期:2019-08-29 00:00:00
abstract::The actinopterygians comprise nearly one-half of all extant vertebrate species and are very important for human well-being. However, the phylogenetic relationships among certain groups within the actinopterygians are still uncertain, and debates about these relationships have continued for a long time. Along with the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00665
更新日期:2012-01-01 00:00:00
abstract::Sickle cell anaemia (SCA) is characterized by reduced red blood cell (RBC) deformability and nitric oxide (NO) bioavailability. The aim of the study was to investigate whether exercise might affect these parameters in SCA. SCA patients and healthy controls (AA) performed an acute submaximal exercise test until subject...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48364-1
更新日期:2019-08-14 00:00:00
abstract::Ga-68 Prostate-Specific Membrane Antigen PET/CT is a new tool for the assessment of prostate cancer. Standard imaging time is 60 minutes post injection of radiotracer. At 60 minutes, there is physiologic accumulation of radiotracer in the urinary bladder which may cause some lesions in its vicinity to be obscured. Our...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59296-6
更新日期:2020-02-17 00:00:00
abstract::Melon (Cucumis melo L.) is a very important crop throughout the world and has great economic importance, in part due to its nutritional properties. It prefers well-drained soil with low acidity and has a strong demand for water during fruit set. Therefore, a correct water balance-involving aquaporins-is necessary to m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79250-w
更新日期:2020-12-17 00:00:00
abstract::Bast fibres are long extraxylary cells which mechanically support the phloem and they are divided into xylan- and gelatinous-type, depending on the composition of their secondary cell walls. The former, typical of jute/kenaf bast fibres, are characterized by the presence of xylan and a high degree of lignification, wh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05200-8
更新日期:2017-07-10 00:00:00
abstract::We successfully realised plasmon-driven selective reduction reactions of 2-amino-5-nitrobenzenethiol (2A-5-NBT) to 3,3'-dimercapto-4,4'-diaminoazobenzene , an azobenzene derivative, using surface-enhanced Raman scattering (SERS) spectroscopy, and supported by the theoretical calculations. The SERS spectra demonstrated...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10269
更新日期:2015-06-01 00:00:00
abstract::Applications of ferroelectric materials in modern microelectronics will be greatly encouraged if the thermal incompatibility between inorganic ferroelectrics and semiconductor devices is overcome. Here, solution-processable layers of the most commercial ferroelectric compound--morphotrophic phase boundary lead zircona...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep20143
更新日期:2016-02-03 00:00:00
abstract::Method for production of alpha emitter 149Tb by irradiation of 151Eu with 70 MeV 3He nuclei is proposed. For the first time, the cross sections for the formation of isotopes 149,150,151,152Tb were measured experimentally using a stack foil technique in the 3He particles energy range 70 → 12 MeV. The thick target yield...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-57436-6
更新日期:2020-01-16 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-57959-y
更新日期:2020-02-05 00:00:00
abstract::Given new distribution patterns of the endangered North Atlantic right whale (NARW; Eubalaena glacialis) population in recent years, an improved understanding of spatio-temporal movements are imperative for the conservation of this species. While so far visual data have provided most information on NARW movements, pas...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13359-3
更新日期:2017-10-18 00:00:00
abstract::Modeling the dynamic nature of protein-ligand binding with atomistic simulations is one of the main challenges in computational biophysics, with important implications in the drug design process. Although in the past few years hardware and software advances have significantly revamped the use of molecular simulations,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08445-5
更新日期:2017-08-16 00:00:00
abstract::Dosimetry models using preclinical positron emission tomography (PET) data are commonly employed to predict the clinical radiological safety of novel radiotracers. However, unbiased clinical safety profiling remains difficult during the translational exercise from preclinical research to first-in-human studies for nov...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72830-w
更新日期:2020-09-29 00:00:00
abstract::Although the association between visual acuity (VA) and vision-related quality of life (VRQoL) has been well reported in patients with type 2 diabetes mellitus (T2DM), little is known about how unilateral and bilateral VA affects daily performance in such patients. For this cross-sectional study, patients were recruit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79483-9
更新日期:2021-01-11 00:00:00
abstract::Direct growth of MoS2 nanowalls on vapor grown carbon nanofibers (VGCNFs) has been achieved using a microwave-assisted hydrothermal (MAH) method under an acidic condition. The acidic condition was obtained through the addition of an HCl aqueous solution. We demonstrate that the HCl not only modifies the pH value for l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05805-z
更新日期:2017-07-20 00:00:00
abstract::We show a hybrid structure consisting of Si film with photonic crystal surface and random triangular gold grooves reflector at the bottom, which is capable of realizing efficient, broad-band, wide-angle optical absorption. It is numerically demonstrated that the enhanced absorption in a broad wavelength range (0.3-9.9...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12794
更新日期:2015-08-04 00:00:00
abstract::Food constitutes a fuel of life for human beings. It is therefore of chief importance that their recognition system readily identifies the most relevant properties of food by drawing on semantic memory. One of the most relevant properties to be considered is the level of processing impressed by humans on food. We hypo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43919-8
更新日期:2019-05-15 00:00:00
abstract::Microbial life below the seafloor has changed over geological time, but these changes are often not obvious, as they are not recorded in the sediment. Sulphur (S) isotope values in pyrite extracted from a Plio- to Holocene sequence of the Peru Margin (Ocean Drilling Program, ODP, Site 1229) show a down-core pattern th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36943-7
更新日期:2019-01-24 00:00:00
abstract::Seeded polymerisation of proteins forming amyloid fibres and their spread in tissues has been implicated in the pathogenesis of multiple neurodegenerative diseases: so called "prion-like" mechanisms. While ex vivo mammalian prions, composed of multichain assemblies of misfolded host-encoded prion protein (PrP), act as...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36700-w
更新日期:2019-01-23 00:00:00
abstract::Elevated nitrogen associated with global change is believed to promote the invasion of many vigorous exotic plants. However, it is unclear how a weak exotic plant will respond to elevated nitrogen in the future. In this study, the competitive outcome of a weak invasive plant (Galinsoga quadriradiata) and two non-invas...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21546-z
更新日期:2018-02-16 00:00:00
abstract::Interactions between human cytomegalovirus (HCMV) infection and environmental factors can increase susceptibility to essential hypertension (EH). Although endothelial dysfunction is the initial factor of EH, the epigenetic mechanisms through which HCMV infection induces endothelial cell dysfunction are poorly understo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58680-6
更新日期:2020-02-10 00:00:00
abstract::The study of postsynaptic excitation to inhibition (E/I ratio) imbalances in human brain diseases, is a highly relevant functional measurement poorly investigated due to postmortem degradation of synaptic receptors. We show that near-simultaneous recording of microtransplanted synaptic receptors after simulated morgue...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65377-3
更新日期:2020-05-25 00:00:00
abstract::We propose a mechanism of ultrahigh-Q metallic nanocavity resonances that involves an efficient loss-compensation scheme favorable for room-temperature operation. We theoretically show that surface plasmon-polaritons excited on the entrance and exit interfaces of a metallic nanocavity array efficiently transfer extern...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07124
更新日期:2014-11-20 00:00:00
abstract::The effect of substitution of Nb by Mo in Nb40Ti30Ni30 was investigated with respect to microstructural features and hydrogen dissolution, diffusion and permeation. As-cast Nb40-xMoxTi30Ni30 (x = 0, 5, 10) alloys consist of primary bcc-Nb phase and binary eutectic (bcc-Nb + B2-TiNi). The substitution of Nb by Mo reduc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00335-0
更新日期:2017-03-16 00:00:00
abstract::Oxidative stress plays a role in the progression of chronic heart failure (CHF). We investigated whether systemic oxidative stress is linked to exercise intolerance and skeletal muscle abnormalities in patients with CHF. We recruited 30 males: 17 CHF patients, 13 healthy controls. All participants underwent blood test...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81736-0
更新日期:2021-01-26 00:00:00
abstract::In this study, novel ZnS@In2S3 core@shell hollow nanospheres were fabricated by a facile refluxing method for the first time, and the formation mechanism of hollow structure with interior architecture was discussed based on ion-exchange Ostwald ripening. As the photocatalytic material for degradation of gaseous o-Dich...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16732-4
更新日期:2017-11-27 00:00:00
abstract::De novo uridine-diphosphate-N-acetylglucosamine (UDP-GlcNAc) biosynthesis requires glucose, glutamine, acetyl-CoA and uridine, however GlcNAc salvaged from glycoconjugate turnover and dietary sources also makes a significant contribution to the intracellular pool. Herein we ask whether dietary GlcNAc regulates nutrien...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23043
更新日期:2016-03-14 00:00:00
abstract::Lateral organ boundaries domain (LBD) proteins are plant-specific transcription factors that play a crucial role in growth and development, as well as metabolic processes. However, knowledge of the function of LBD proteins in Camellia sinensis is limited, and no systematic investigations of the LBD family have been re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52027-6
更新日期:2019-10-30 00:00:00
abstract::Higher and lower levels of alertness typically lead to a leftward and rightward bias in attention, respectively. This relationship between alertness and spatial attention potentially has major implications for health and safety. The current study examined alertness and spatial attention under simulated shiftworking co...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-020-71800-6
更新日期:2020-09-11 00:00:00