Abstract：
:Food constitutes a fuel of life for human beings. It is therefore of chief importance that their recognition system readily identifies the most relevant properties of food by drawing on semantic memory. One of the most relevant properties to be considered is the level of processing impressed by humans on food. We hypothesized that recognition of raw food capitalizes on sensory properties and that of transformed food on functional properties, consistently with the hypothesis of a sensory-functional organization of semantic knowledge. To test this hypothesis, patients with Alzheimer's disease, frontotemporal dementia, primary progressive aphasia, and healthy controls performed lexical-semantic tasks with food (raw and transformed) and non-food (living and nonliving) stimuli. Correlations between task performance and local grey matter concentration (VBM) and white matter fractional anisotropy (TBSS) led to two main findings. First, recognition of raw food and living things implicated occipital cortices, typically involved in processing sensory information and, second, recognition of processed food and nonliving things implicated the middle temporal gyrus and surrounding white matter tracts, regions that have been associated with functional properties. In conclusion, the present study confirms and extends the hypothesis of a sensory and a functional organization of semantic knowledge.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Vignando M,Aiello M,Rinaldi A,Cattarruzza T,Mazzon G,Manganotti P,Eleopra R,Rumiati RIdoi
10.1038/s41598-019-43919-8subject
Has Abstractpub_date
2019-05-15 00:00:00pages
7439issue
1issn
2045-2322pii
10.1038/s41598-019-43919-8journal_volume
9pub_type
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