A Poroelastic Model of a Fibrous-Porous Tissue Engineering Scaffold.

abstract：:The transfer of the flexor hallucis longus tendon or flexor digitorum longus tendon is frequently used for the treatment of posterior tibial tendon insufficiency or chronic Achilles tendinopathy. According to several anatomical studies, harvesting the flexor hallucis longus (FHL) tendon may cause nerve injury. Sixty-e...

journal_title：Scientific reports

authors： Mao H,Dong W,Shi Z,Yin W,Xu D,Wapner KL

更新日期：2017-10-27 00:00:00

abstract：:Given new distribution patterns of the endangered North Atlantic right whale (NARW; Eubalaena glacialis) population in recent years, an improved understanding of spatio-temporal movements are imperative for the conservation of this species. While so far visual data have provided most information on NARW movements, pas...

journal_title：Scientific reports

authors： Davis GE,Baumgartner MF,Bonnell JM,Bell J,Berchok C,Bort Thornton J,Brault S,Buchanan G,Charif RA,Cholewiak D,Clark CW,Corkeron P,Delarue J,Dudzinski K,Hatch L,Hildebrand J,Hodge L,Klinck H,Kraus S,Martin B,Mellin

更新日期：2017-10-18 00:00:00

abstract：:In total, 303 randomly selected clinical Mycobacterium tuberculosis (MTB) isolates from 303 patients (collected January to December 2012) in central Taiwan were examined. The major lineages found were Beijing (N = 114, 37.62%), Haarlem (N = 76, 25.08%) and East African-Indian (EAI) (N = 42, 13.86%). Notably, younger p...

journal_title：Scientific reports

authors： Chen YY,Chang JR,Wu CD,Yeh YP,Yang SJ,Hsu CH,Lin MC,Tsai CF,Lin MS,Su IJ,Dou HY

更新日期：2017-07-14 00:00:00

abstract：:Liquid foams are classified into a dry foam and a wet foam, empirically judging from the liquid fraction or the shape of the gas bubbles. It is known that physical properties such as elasticity and diffusion are different between the dry foam and the wet foam. Nevertheless, definitions of those states have been vague ...

journal_title：Scientific reports

authors： Furuta Y,Oikawa N,Kurita R

更新日期：2016-11-22 00:00:00

abstract：:The alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) is known to trigger the adaptive response by inducing the ada-regulon - consisting of three DNA repair enzymes Ada, AlkB, AlkA and the enigmatic AidB. We have applied custom designed tiling arrays to study transcriptional changes in Escherichia coli foll...

journal_title：Scientific reports

authors： Booth JA,Thomassen GO,Rowe AD,Weel-Sneve R,Lagesen K,Kristiansen KI,Bjørås M,Rognes T,Lindvall JM

更新日期：2013-10-25 00:00:00

abstract：:The natural alkaloid berberine has several pharmacological properties and recently received attention as a potential anticancer agent. In this work, we investigated the molecular mechanisms underlying the anti-tumor effect of berberine on glioblastoma U343 and pancreatic carcinoma MIA PaCa-2 cells. Human dermal fibrob...

journal_title：Scientific reports

authors： Agnarelli A,Natali M,Garcia-Gil M,Pesi R,Tozzi MG,Ippolito C,Bernardini N,Vignali R,Batistoni R,Bianucci AM,Marracci S

更新日期：2018-07-13 00:00:00

abstract：:Deep venous thrombosis (DVT) is a common complication of orthopedic surgery. Genetic risk factors and high heritability carried a substantial risk of DVT. In this study, we aimed to investigate the potential association in the Han Chinese population between the polymorphisms of BDKRB2 and KNG1 and DVT after orthopedic...

journal_title：Scientific reports

authors： Wang Q,Cheng G,Wang X,Wang D,Yang Y,Chen K,Ye J,Qing Z

更新日期：2018-11-26 00:00:00

abstract：:With modern scanning probe microscopes, it is possible to manipulate surface structures even at the atomic level. However, manipulation of nanoscale objects such as clusters is often more relevant and also more challenging due to the complicated interactions between the surface, cluster and apparatus. We demonstrate t...

journal_title：Scientific reports

authors： Hynninen T,Cabailh G,Foster AS,Barth C

更新日期：2013-01-01 00:00:00

abstract：:The eg-orbital double-exchange mechanism as the core of physics of colossal magnetoresistance (CMR) manganites is well known, which usually covers up the role of super-exchange at the t2g-orbitals. The role of the double-exchange mechanism is maximized in La0.7Ca0.3MnO3, leading to the concurrent metal-insulator trans...

journal_title：Scientific reports

authors： Liu MF,Du ZZ,Xie YL,Li X,Yan ZB,Liu JM

更新日期：2015-04-24 00:00:00

abstract：:Clostridium ljungdahlii derives energy by lithotrophic and organotrophic acetogenesis. C. ljungdahlii was grown organotrophically with fructose and also lithotrophically, either with syngas - a gas mixture containing hydrogen (H2), carbon dioxide (CO2), and carbon monoxide (CO), or with H2 and CO2. Gene expression was...

journal_title：Scientific reports

authors： Aklujkar M,Leang C,Shrestha PM,Shrestha M,Lovley DR

更新日期：2017-10-13 00:00:00

abstract：:Calcium oxalate monohydrate (COM) crystals cause kidney stone disease by still unclear mechanisms. The present study aimed to characterize changes in secretion of proteins from basolateral compartment of renal tubular epithelial cells after exposure to COM crystals and then correlated them with the stone pathogenesis....

journal_title：Scientific reports

authors： Chiangjong W,Thongboonkerd V

更新日期：2016-04-05 00:00:00

abstract：:Propofol sedation has been applied during esophagogastroduodenoscopy procedures, but whether topical pharyngeal anesthesia should be administered at the same time has rarely been reported. Our study examined the role of topical pharyngeal anesthesia in sedated endoscopies in a randomized controlled double-blinded clin...

journal_title：Scientific reports

authors： Sun X,Xu Y,Zhang X,Li A,Zhang H,Yang T,Liu Y

更新日期：2018-04-27 00:00:00

abstract：:Ancient statues are usually fragile and have a tendency to deteriorate over time, developing cracks, corrosion, and losing color. Before any intervention on the object of art, a conservator must map degradation and take measurements. Deterioration mapping is an extremely long process, as the conservator or restorer mu...

journal_title：Scientific reports

authors： Nasri A,Huang X

更新日期：2020-12-14 00:00:00

abstract：:Multiplexed or simultaneous detection of multiple analytes is a valuable tool in many analytical applications. However, complications caused by the presence of interfering compounds in a sample form a major drawback in existing molecular sensor technologies, particularly in multi-analyte systems. Although separating a...

journal_title：Scientific reports

authors： Kasera S,Herrmann LO,del Barrio J,Baumberg JJ,Scherman OA

更新日期：2014-10-30 00:00:00

abstract：:The relative effects of internal fixation strategies for intertrochanteric fracture after operation remain uncertain. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to address this important issue. We searched PubMed, EMBASE and CENTRAL for RCTs that compared different intern...

journal_title：Scientific reports

authors： Yu J,Zhang C,Li L,Kwong JS,Xue L,Zeng X,Tang L,Li Y,Sun X

更新日期：2015-12-11 00:00:00

abstract：:Post-transcriptional gene regulation by microRNAs (miRNAs) is involved in memory formation. However, the roles of individual miRNAs in these processes remain largely unknown. In this study, we want to clarify the role of miR-181a in hippocampus-dependent memory formation. A transient increase in miR-181a expression wa...

journal_title：Scientific reports

authors： Zhang SF,Chen JC,Zhang J,Xu JG

更新日期：2017-08-16 00:00:00

abstract：:Micronutrients are essential for survival and growth for all the organisms including pathogens. In this manuscript, we report that zinc (Zn) chelator N,N,N',N'-tetrakis(2-pyridinylmethyl)-1,2-ethylenediamine (TPEN) affects growth and viability of intracellular pathogen Leishmania donovani (LD) by a concentration and t...

journal_title：Scientific reports

authors： Saini S,Bharati K,Shaha C,Mukhopadhyay CK

更新日期：2017-09-05 00:00:00

abstract：:Recent clinical trials have investigated the benefit of combining tyrosine kinase inhibitors (TKIs) and cytoreductive nephrectomy (CN) in patients with metastatic renal cell carcinoma. Our goal is to determine whether the perioperative use of TKIs increases the postoperative morbidity following CN in renal cell carcin...

journal_title：Scientific reports

authors： Carvalho FLF,Zheng C,Witmer K,O'neill J,Lynch JH,Kowalczyk KJ

更新日期：2019-10-24 00:00:00

abstract：:In eye movement perimetry (EMP), the saccadic reaction time (SRT) to 'seen' visual stimuli are delayed in glaucoma. Evaluating SRT behaviour in hemi-field sectors could refine its clinical implication. The development phase included 60 controls retrospectively and for the test cohort in evaluation phase, another 30 he...

journal_title：Scientific reports

authors： Mazumdar D,Meethal NSK,George R,Pel JJM

更新日期：2021-01-29 00:00:00

abstract：:Evasion of the potent tumour suppressor activity of p53 is one of the hurdles that must be overcome for cancer cells to escape normal regulation of cellular proliferation and survival. In addition to frequent loss of function mutations, p53 wild-type activity can also be suppressed post-translationally through several...

journal_title：Scientific reports

authors： Gerhart SV,Kellner WA,Thompson C,Pappalardi MB,Zhang XP,Montes de Oca R,Penebre E,Duncan K,Boriack-Sjodin A,Le B,Majer C,McCabe MT,Carpenter C,Johnson N,Kruger RG,Barbash O

更新日期：2018-06-26 00:00:00

abstract：:Identification of AD (Alzheimer's disease)-related genes obtained from blood samples is crucial for early AD diagnosis. We used three public datasets, ADNI, AddNeuroMed1 (ANM1), and ANM2, for this study. Five feature selection methods and five classifiers were used to curate AD-related genes and discriminate AD patien...

journal_title：Scientific reports

authors： Lee T,Lee H

更新日期：2020-02-26 00:00:00

abstract：:Multisensory integration is a powerful mechanism for constructing body awareness and key for the sense of selfhood. Recent evidence has shown that the specialised C tactile modality that gives rise to feelings of pleasant, affective touch, can enhance the experience of body ownership during multisensory integration. N...

journal_title：Scientific reports

authors： Panagiotopoulou E,Filippetti ML,Tsakiris M,Fotopoulou A

更新日期：2017-10-10 00:00:00

abstract：:In the present work, the mechanisms involved in the recently reported antiviral activity of zebrafish C-reactive protein-like protein (CRP1-7) against the spring viraemia of carp rhabdovirus (SVCV) in fish are explored. The results neither indicate blocking of the attachment or the binding step of the viral replicatio...

journal_title：Scientific reports

authors： Bello-Perez M,Pereiro P,Coll J,Novoa B,Perez L,Falco A

更新日期：2020-01-17 00:00:00

abstract：:The mechanisms underlying the discovery of abstract rules like those found in natural language may be evolutionarily tuned to speech, according to previous research. When infants hear speech sounds, they can learn rules that govern their combination, but when they hear non-speech sounds such as sine-wave tones, they f...

journal_title：Scientific reports

authors： Ferguson B,Lew-Williams C

更新日期：2016-05-06 00:00:00

abstract：:Weathered granite of ion-adsorption rare earth elements (REEs) ore collected at Jiangxi Province, China was investigated to identify the minerals abundant in REEs. The analyses of scanning electron microscopy (SEM)-energy dispersive spectrometry (EDS) and laser ablation inductively coupled plasma mass spectrometry (LA...

journal_title：Scientific reports

authors： Mukai H,Kon Y,Sanematsu K,Takahashi Y,Ito M

更新日期：2020-11-19 00:00:00

abstract：:Hepatic metabolic stability is a key pharmacokinetic parameter in drug discovery. Metabolic stability is usually assessed in microsomal fractions and only the best compounds progress in the drug discovery process. A high-throughput single time point substrate depletion assay in rat liver microsomes (RLM) is employed a...

journal_title：Scientific reports

authors： Siramshetty VB,Shah P,Kerns E,Nguyen K,Yu KR,Kabir M,Williams J,Neyra J,Southall N,Nguyễn ÐT,Xu X

更新日期：2020-11-26 00:00:00

abstract：:Growth factors have great therapeutic potential for various disease therapy and tissue engineering applications. However, their clinical efficacy is hampered by low bioavailability, rapid degradation in vivo and non-specific biodistribution. Nanoparticle based delivery systems are being evaluated to overcome these lim...

journal_title：Scientific reports

authors： Choi WI,Sahu A,Vilos C,Kamaly N,Jo SM,Lee JH,Tae G

更新日期：2017-10-30 00:00:00

abstract：:Ophidian accidents are considered an important neglected tropical disease by the World Health Organization. Particularly in Latin America, Bothrops snakes are responsible for the majority of the snakebite envenomings that are not efficiently treated by conventional serum therapy. Thus, the search for simple and effici...

journal_title：Scientific reports

authors： Salvador GHM,Cardoso FF,Gomes AA,Cavalcante WLG,Gallacci M,Fontes MRM

更新日期：2019-01-24 00:00:00

abstract：:Several microbes, including Staphylococcus epidermidis (S. epidermidis), a Gram-positive bacterium, live inside the human nasal cavity as commensals. The role of these nasal commensals in host innate immunity is largely unknown, although bacterial interference in the nasal microbiome may promote ecological competition...

journal_title：Scientific reports

authors： Chen HW,Liu PF,Liu YT,Kuo S,Zhang XQ,Schooley RT,Rohde H,Gallo RL,Huang CM

更新日期：2016-06-16 00:00:00

abstract：:Alzheimer disease and other dementias have become the 7th cause of death worldwide. Still lacking a cure, an early detection of the disease in order to provide the best intervention is crucial. To develop an assessment system for the general public, speech analysis is the optimal solution since it reflects the speaker...

journal_title：Scientific reports

authors： Chien YW,Hong SY,Cheah WT,Yao LH,Chang YL,Fu LC

更新日期：2019-12-20 00:00:00