Abstract:
:Multiplexed or simultaneous detection of multiple analytes is a valuable tool in many analytical applications. However, complications caused by the presence of interfering compounds in a sample form a major drawback in existing molecular sensor technologies, particularly in multi-analyte systems. Although separating analytes through extraction or chromatography can partially address the problem of interferents, there remains a need for developing direct observational tools capable of multiplexing that can be applied in situ. Surface-enhanced Raman Spectroscopy (SERS) is an optical molecular finger-printing technique that has the ability to resolve analytes from within mixtures. SERS has attracted much attention for its potential in multiplexed sensing but it has been limited in its quantitative abilities. Here, we report a facile supramolecular SERS-based method for quantitative multiplex analysis of small organic molecules in aqueous environments such as human urine.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Kasera S,Herrmann LO,del Barrio J,Baumberg JJ,Scherman OAdoi
10.1038/srep06785subject
Has Abstractpub_date
2014-10-30 00:00:00pages
6785issn
2045-2322pii
srep06785journal_volume
4pub_type
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