Quantitative multiplexing with nano-self-assemblies in SERS.

Abstract:

:Multiplexed or simultaneous detection of multiple analytes is a valuable tool in many analytical applications. However, complications caused by the presence of interfering compounds in a sample form a major drawback in existing molecular sensor technologies, particularly in multi-analyte systems. Although separating analytes through extraction or chromatography can partially address the problem of interferents, there remains a need for developing direct observational tools capable of multiplexing that can be applied in situ. Surface-enhanced Raman Spectroscopy (SERS) is an optical molecular finger-printing technique that has the ability to resolve analytes from within mixtures. SERS has attracted much attention for its potential in multiplexed sensing but it has been limited in its quantitative abilities. Here, we report a facile supramolecular SERS-based method for quantitative multiplex analysis of small organic molecules in aqueous environments such as human urine.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Kasera S,Herrmann LO,del Barrio J,Baumberg JJ,Scherman OA

doi

10.1038/srep06785

subject

Has Abstract

pub_date

2014-10-30 00:00:00

pages

6785

issn

2045-2322

pii

srep06785

journal_volume

4

pub_type

杂志文章
  • Stem cells catalyze cartilage formation by neonatal articular chondrocytes in 3D biomimetic hydrogels.

    abstract::Cartilage loss is a leading cause of disability among adults and effective therapy remains elusive. Neonatal chondrocytes (NChons) are an attractive allogeneic cell source for cartilage repair, but their clinical translation has been hindered by scarce donor availability. Here we examine the potential for catalyzing c...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep03553

    authors: Lai JH,Kajiyama G,Smith RL,Maloney W,Yang F

    更新日期:2013-12-19 00:00:00

  • Non-random distribution of homo-repeats: links with biological functions and human diseases.

    abstract::The biological function of multiple repetitions of single amino acids, or homo-repeats, is largely unknown, but their occurrence in proteins has been associated with more than 20 hereditary diseases. Analysing 122 bacterial and eukaryotic genomes, we observed that the number of proteins containing homo-repeats is sign...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep26941

    authors: Lobanov MY,Klus P,Sokolovsky IV,Tartaglia GG,Galzitskaya OV

    更新日期:2016-06-03 00:00:00

  • The histone 3 lysine 9 methyltransferase inhibitor chaetocin improves prognosis in a rat model of high salt diet-induced heart failure.

    abstract::Histone acetylation has been linked to cardiac hypertrophy and heart failure. However, the pathological implications of changes in histone methylation and the effects of interventions with histone methyltransferase inhibitors for heart failure have not been fully clarified. Here, we focused on H3K9me3 status in the he...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep39752

    authors: Ono T,Kamimura N,Matsuhashi T,Nagai T,Nishiyama T,Endo J,Hishiki T,Nakanishi T,Shimizu N,Tanaka H,Ohta S,Suematsu M,Ieda M,Sano M,Fukuda K,Kaneda R

    更新日期:2017-01-04 00:00:00

  • Physiologic heart rate dependency of the PQ interval and its sex differences.

    abstract::On standard electrocardiogram (ECG) PQ interval is known to be moderately heart rate dependent, but no physiologic details of this dependency have been established. At the same time, PQ dynamics is a clear candidate for non-invasive assessment of atrial abnormalities including the risk of atrial fibrillation. We studi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59480-8

    authors: Toman O,Hnatkova K,Smetana P,Huster KM,Šišáková M,Barthel P,Novotný T,Schmidt G,Malik M

    更新日期:2020-02-13 00:00:00

  • Sequentially hetero-functional, topological polymers by step-growth thiol-yne approach.

    abstract::Sequence-controlled polymers (SCPs) such as DNA and proteins play an important role in biology. Many efforts have been devoted to synthesize SCPs in the past half a century. However, to our knowledge, the artificial sequences containing independently functional groups have never been reported. Here, we present a facil...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep04387

    authors: Han J,Zheng Y,Zhao B,Li S,Zhang Y,Gao C

    更新日期:2014-03-17 00:00:00

  • On the first evidence of exchange-bias feature in magnetically contrasted consolidates made from CoFe2O4-CoO core-shell nanoparticles.

    abstract::Hetero-nanostructures based on magnetic contrast oxides have been prepared as highly dense nanoconsolidates. Cobalt ferrite-cobalt oxide core-shell type nanoparticles (NPs) were synthesized by seed mediated growth in polyol and subsequently consolidated by Spark Plasma Sintering (SPS) at 500 °C for a few minutes while...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-55649-y

    authors: Flores-Martinez N,Franceschin G,Gaudisson T,Haj-Khlifa S,Derouich SG,Yaacoub N,Grenèche JM,Menguy N,Valenzuela R,Ammar S

    更新日期:2019-12-19 00:00:00

  • Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3.

    abstract::Phelan McDermid Syndrome (PMDS) is a genetic disorder characterized by features of Autism spectrum disorders. Similar to reports of Zn deficiency in autistic children, we have previously reported high incidence of Zn deficiency in PMDS. However, the underlying mechanisms are currently not well understood. Here, using ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep45190

    authors: Pfaender S,Sauer AK,Hagmeyer S,Mangus K,Linta L,Liebau S,Bockmann J,Huguet G,Bourgeron T,Boeckers TM,Grabrucker AM

    更新日期:2017-03-27 00:00:00

  • Membrane glycerolipidome of soybean root hairs and its response to nitrogen and phosphate availability.

    abstract::Root hairs are tubular extensions of specific root epidermal cells important in plant nutrition and water absorption. To determine membrane glycerolipids in root hairs and roots may differ, as well as their respective response to nutrient availability, this study analyzed the membrane glycerolipid species in soybean r...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep36172

    authors: Wei F,Fanella B,Guo L,Wang X

    更新日期:2016-11-04 00:00:00

  • Exploring the effect of nsSNPs in human YPEL3 gene in cellular senescence.

    abstract::YPEL3 that induces cellular senescence in both normal and tumour cells of humans may show altered expression under the influence of incidental mutations. In this study, we proposed the first structure of Native YPEL3 protein and its five possible deleterious mutants-V40M, C61Y, G98R, G108S, and A131T and predicted the...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-72333-8

    authors: Singh A,Thakur M,Singh SK,Sharma LK,Chandra K

    更新日期:2020-09-17 00:00:00

  • Tactile perception of randomly rough surfaces.

    abstract::Most everyday surfaces are randomly rough and self-similar on sufficiently small scales. We investigated the tactile perception of randomly rough surfaces using 3D-printed samples, where the topographic structure and the statistical properties of scale-dependent roughness were varied independently. We found that the t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-72890-y

    authors: Sahli R,Prot A,Wang A,Müser MH,Piovarči M,Didyk P,Bennewitz R

    更新日期:2020-09-25 00:00:00

  • Linked colour imaging benefits the endoscopic diagnosis of distal gastric diseases.

    abstract::Gastric diseases are common in China, and gastroduodenoscopy could provide accurate diagnoses. Our previous study verified that linked colour imaging (LCI) can improve endoscopic diagnostic accuracy. This study aimed for the first time to establish an LCI-based endoscopic model called colour-microstructure-vessel (CMV...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05847-3

    authors: Sun X,Bi Y,Dong T,Min M,Shen W,Xu Y,Liu Y

    更新日期:2017-07-17 00:00:00

  • Hepatocellular carcinoma: thyroid hormone promotes tumorigenicity through inducing cancer stem-like cell self-renewal.

    abstract::Cancer stem-like cells (CSCs) play a key role in maintaining the aggressiveness of hepatocellular carcinoma (HCC), but the cell-biological regulation of CSCs is unclear. In the study, we report that thyroid hormone (TH) promotes cell self-renewal in HCC cells. TH also increases the percentage of CD90 + HCC cells and p...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25183

    authors: Wang T,Xia L,Ma S,Qi X,Li Q,Xia Y,Tang X,Cui D,Wang Z,Chi J,Li P,Feng YX,Xia Q,Zhai B

    更新日期:2016-05-12 00:00:00

  • Nano-structured glaucoma drainage implant safely and significantly reduces intraocular pressure in rabbits via post-operative outflow modulation.

    abstract::Glaucoma is a leading cause of irreversible vision loss predicted to affect more than 100 million people by 2040. Intraocular pressure (IOP) reduction prevents development of glaucoma and vision loss from glaucoma. Glaucoma surgeries reduce IOP by facilitating aqueous humor outflow through a vent fashioned from the wa...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-69687-4

    authors: Parikh KS,Josyula A,Omiadze R,Ahn JY,Ha Y,Ensign LM,Hanes J,Pitha I

    更新日期:2020-07-31 00:00:00

  • In-situ ToF-SIMS analyses of deuterium re-distribution in austenitic steel AISI 304L under mechanical load.

    abstract::Hydrocarbons fuel our economy. Furthermore, intermediate goods and consumer products are often hydrocarbon-based. Beside all the progress they made possible, hydrogen-containing substances can have severe detrimental effects on materials exposed to them. Hydrogen-assisted failure of iron alloys has been recognised mor...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-60370-2

    authors: Röhsler A,Sobol O,Hänninen H,Böllinghaus T

    更新日期:2020-02-27 00:00:00

  • Cell type specific gene expression profiling reveals a role for complement component C3 in neutrophil responses to tissue damage.

    abstract::Tissue damage induces rapid recruitment of leukocytes and changes in the transcriptional landscape that influence wound healing. However, the cell-type specific transcriptional changes that influence leukocyte function and tissue repair have not been well characterized. Here, we employed translating ribosome affinity ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-72750-9

    authors: Houseright RA,Rosowski EE,Lam PY,Tauzin SJM,Mulvaney O,Dewey CN,Huttenlocher A

    更新日期:2020-09-24 00:00:00

  • Ocular Manifestations of Leukemia and Results of Treatment with Intravitreal Methotrexate.

    abstract::Ocular involvement in leukemia is considered rare. Ocular symptoms can be the presenting signs of leukemia, they can appear after diagnosis has been established, or they can be the first manifestation of a relapse after remission. We report, to the best of our knowledge for the first time, the ocular manifestation of ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-58654-8

    authors: Vishnevskia-Dai V,Sella King S,Lekach R,Fabian ID,Zloto O

    更新日期:2020-02-06 00:00:00

  • Binding of mycotoxins to proteins involved in neuronal plasticity: a combined in silico/wet investigation.

    abstract::We have applied a combined computational procedure based on inverse and direct docking in order to identify putative protein targets of a panel of mycotoxins and xenobiotic compounds that can contaminate food and that are known to have several detrimental effects on human health. This procedure allowed us to identify ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-15148-4

    authors: Scafuri B,Varriale A,Facchiano A,D'Auria S,Raggi ME,Marabotti A

    更新日期:2017-11-09 00:00:00

  • In vitro inactivation of SARS-CoV-2 by commonly used disinfection products and methods.

    abstract::Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is currently a global pandemic, and there are limited laboratory studies targeting pathogen resistance. This study aimed to investigate the effect of selected disinfection products and methods on the inactivation of SARS-CoV-2 in the laboratory. We...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-021-82148-w

    authors: Xiling G,Yin C,Ling W,Xiaosong W,Jingjing F,Fang L,Xiaoyan Z,Yiyue G,Ying C,Lunbiao C,Liubo Z,Hong S,Yan X

    更新日期:2021-01-28 00:00:00

  • Phenotyping and susceptibility of established porcine cells lines to African Swine Fever Virus infection and viral production.

    abstract::African swine fever virus (ASFV) is a highly pathogenic, double-stranded DNA virus with a marked tropism for cells of the monocyte-macrophage lineage, affecting swine species and provoking severe economic losses and health threats. In the present study, four established porcine cell lines, IPAM-WT, IPAM-CD163, C∆2+ an...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-09948-x

    authors: Sánchez EG,Riera E,Nogal M,Gallardo C,Fernández P,Bello-Morales R,López-Guerrero JA,Chitko-McKown CG,Richt JA,Revilla Y

    更新日期:2017-09-04 00:00:00

  • COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1.

    abstract::Fibrillar collagen COL6α3 in adipose tissue has been associated with obesity, inflammation, insulin resistance and cancer. We here aimed to identify novel transcriptional regulators of COL6A3 expression. Based on a transcriptome dataset of adipose tissue, we identified strong correlations for 56 genes with COL6A3 mRNA...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-77406-2

    authors: Dankel SN,Grytten E,Bjune JI,Nielsen HJ,Dietrich A,Blüher M,Sagen JV,Mellgren G

    更新日期:2020-11-19 00:00:00

  • Preparation of Zr(Mo,W)2O8 with a larger negative thermal expansion by controlling the thermal decomposition of Zr(Mo,W)2(OH,Cl)2∙2H2O.

    abstract::Solid solutions of Zr(Mo,W)2O7(OH,Cl)2∙2H2O with a preset ratio of components were prepared by a hydrothermal method. The chemical composition of the solutions was determined by energy dispersive X-ray spectroscopy (EDX). For all the samples of ZrMoxW2-xO7(OH,Cl)2∙2H2O (x = 0.0, 0.2, 0.4, 0.6, 0.8, 1.0, 1.2, 1.4, 1.6,...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-23529-6

    authors: Petrushina MY,Dedova ES,Filatov EY,Plyusnin PE,Korenev SV,Kulkov SN,Derevyannikova EA,Sharafutdinov MR,Gubanov AI

    更新日期:2018-03-28 00:00:00

  • Enhanced STAT3 phosphorylation and PD-L1 expression in myeloid dendritic cells indicate impaired IL-27Ralpha signaling in type 1 diabetes.

    abstract::Interleukin 27 (IL-27), a member of the IL-12 family, is important for T cell differentiation; however, little is known about its effect on dendritic cells (DCs). IL-27 can activate multiple signaling cascades, including the JAK/STAT pathway, and depending on the setting it can both promote and antagonize inflammatory...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-57507-8

    authors: Parackova Z,Vrabcova P,Zentsova I,Kayserova J,Richtrova I,Sojka L,Stechova K,Sumnik Z,Sediva A

    更新日期:2020-01-16 00:00:00

  • Frequency-noise measurements of optical frequency combs by multiple fringe-side discriminator.

    abstract::The frequency noise of an optical frequency comb is routinely measured through the hetherodyne beat of one comb tooth against a stable continuous-wave laser. After frequency-to-voltage conversion, the beatnote is sent to a spectrum analyzer to retrive the power spectral density of the frequency noise. Because narrow-l...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep16338

    authors: Coluccelli N,Cassinerio M,Gambetta A,Laporta P,Galzerano G

    更新日期:2015-11-09 00:00:00

  • Synchronization to a bouncing ball with a realistic motion trajectory.

    abstract::Daily music experience involves synchronizing movements in time with a perceived periodic beat. It has been established for over a century that beat synchronization is less stable for the visual than for the auditory modality. This auditory advantage of beat synchronization gives rise to the hypotheses that the neural...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep11974

    authors: Gan L,Huang Y,Zhou L,Qian C,Wu X

    更新日期:2015-07-07 00:00:00

  • Mast Cell-Intervertebral disc cell interactions regulate inflammation, catabolism and angiogenesis in Discogenic Back Pain.

    abstract::Low back pain (LBP) is a widespread debilitating disorder of significant socio-economic importance and intervertebral disc (IVD) degeneration has been implicated in its pathogenesis. Despite its high prevalence the underlying causes of LBP and IVD degeneration are not well understood. Recent work in musculoskeletal de...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-12666-z

    authors: Wiet MG,Piscioneri A,Khan SN,Ballinger MN,Hoyland JA,Purmessur D

    更新日期:2017-10-02 00:00:00

  • Quantitative bioassay to identify antimicrobial drugs through drug interaction fingerprint analysis.

    abstract::Drug interaction analysis, which reports the extent to which the presence of one drug affects the efficacy of another, is a powerful tool to select potent combinatorial therapies and predict connectivity between cellular components. Combinatorial effects of drug pairs often vary even for drugs with similar mechanism o...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep42644

    authors: Weinstein ZB,Zaman MH

    更新日期:2017-02-16 00:00:00

  • Low on-treatment diastolic blood pressure and cardiovascular outcome: A post-hoc analysis using NHLBI SPRINT Research Materials.

    abstract::Recent studies including the SPRINT trial have shown beneficial effects of intensive systolic blood pressure reduction over the standard approach. The awareness of the J-curve for diastolic blood pressure (DBP) causes some uncertainty regarding the net clinical effects of blood pressure reduction. The current analysis...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-49557-4

    authors: Sobieraj P,Lewandowski J,Siński M,Gaciong Z

    更新日期:2019-09-10 00:00:00

  • The oldest freshwater crabs: claws on dinosaur bones.

    abstract::With approximately 1,500 extant species, freshwater crabs (Decapoda: Brachyura) are among the most diverse decapod crustaceans. Nevertheless, their fossil record is extremely limited: only Potamidae, Potamonautidae and Trichodactylidae are reported up to the Eocene of the Neotropics so far. This work documents unusual...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-56180-w

    authors: Robin N,van Bakel BWM,Hyžný M,Cincotta A,Garcia G,Charbonnier S,Godefroit P,Valentin X

    更新日期:2019-12-27 00:00:00

  • High pressure die casting of Fe-based metallic glass.

    abstract::Soft ferromagnetic Fe-based bulk metallic glass key-shaped specimens with a maximum and minimum width of 25.4 and 5 mm, respectively, were successfully produced using a high pressure die casting (HPDC) method, The influence of die material, alloy temperature and flow rate on the microstructure, thermal stability and s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep35258

    authors: Ramasamy P,Szabo A,Borzel S,Eckert J,Stoica M,Bárdos A

    更新日期:2016-10-11 00:00:00

  • Significant effect of HIV/HAART on oral microbiota using multivariate analysis.

    abstract::Persons infected with HIV are particularly vulnerable to a variety of oral microbial diseases. Although various study designs and detection approaches have been used to compare the oral microbiota of HIV-negative and HIV-positive persons, both with and without highly active antiretroviral therapy (HAART), methods have...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-55703-9

    authors: Griffen AL,Thompson ZA,Beall CJ,Lilly EA,Granada C,Treas KD,DuBois KR 3rd,Hashmi SB,Mukherjee C,Gilliland AE,Vazquez JA,Hagensee ME,Leys EJ,Fidel PL Jr

    更新日期:2019-12-27 00:00:00