Role of Early PET/CT Imaging with 68Ga-PSMA in Staging and Restaging of Prostate Cancer.

abstract：:Psychological factors, specific lifestyles and environmental stressors may influence etiopathogenesis and evolution of chronic diseases. We investigate the association between Chronic Inflammatory Bowel Diseases (IBD) and psychological dimensions such as personality traits, defence mechanisms, and Alexithymia, i.e. de...

journal_title：Scientific reports

authors： La Barbera D,Bonanno B,Rumeo MV,Alabastro V,Frenda M,Massihnia E,Morgante MC,Sideli L,Craxì A,Cappello M,Tumminello M,Miccichè S,Nastri L

更新日期：2017-02-02 00:00:00

abstract：:Despite recent advances, the myocardial microstructure remains imperfectly understood. In particular, bundles of cardiomyocytes have been observed but their three-dimensional organisation remains debated and the associated mechanical consequences unknown. One of the major challenges remains to perform multiscale obser...

journal_title：Scientific reports

authors： Tueni N,Vizet J,Genet M,Pierangelo A,Allain JM

更新日期：2020-11-25 00:00:00

abstract：:Understanding cancer-prone environments is important to efficiently detect and prevent cancers. The associations between miRNA and cancer-prone environments are still largely unknown in gastric cancer (GC). Six miRNAs that are differentially expressed during gastric carcinogenesis were selected, and quantitative real-...

journal_title：Scientific reports

authors： Kim B,Jang J,Heo YJ,Kang SY,Yoo H,Sohn I,Min BH,Kim KM

更新日期：2020-04-20 00:00:00

abstract：:Liver stage Plasmodium parasites reside in a parasitophorous vacuole (PV) that associates with lysosomes. It has previously been shown that these organelles can have beneficial as well as harmful effects on the parasite. Yet it is not clear how the association of lysosomes with the parasite is controlled and how inter...

journal_title：Scientific reports

authors： Niklaus L,Agop-Nersesian C,Schmuckli-Maurer J,Wacker R,Grünig V,Heussler VT

更新日期：2019-05-28 00:00:00

abstract：:The anti-diabetic biguanide drugs metformin (METF) and phenformin (PHEN) may have anti-cancer effects. Biguanides suppress plasma growth factors, but nonetheless, the view that these mitochondrial inhibitors accumulate in tumor tissue to an extent that leads to severe energetic stress or alleviation of hypoxia-induced...

journal_title：Scientific reports

authors： Iversen AB,Horsman MR,Jakobsen S,Jensen JB,Garm C,Jessen N,Breining P,Frøkiær J,Busk M

更新日期：2017-08-25 00:00:00

abstract：:One-carbon metabolism is essential for multiple cellular processes and can be assessed by the concentration of folate metabolites in the blood. One-carbon metabolites serve as methyl donors that are required for epigenetic regulation. Deficiencies in these metabolites are associated with a variety of poor health outco...

journal_title：Scientific reports

authors： Knight AK,Park HJ,Hausman DB,Fleming JM,Bland VL,Rosa G,Kennedy EM,Caudill MA,Malysheva O,Kauwell GPA,Sokolow A,Fisher S,Smith AK,Bailey LB

更新日期：2018-11-15 00:00:00

abstract：:Renewable natural resources, such as solar radiation, rainfall, wind, and geothermal heat, together with ecosystem services, provide the elementary supports for the sustainable development of human society. To improve regional sustainability, we studied the spatial distributions and quantities of renewable natural res...

journal_title：Scientific reports

authors： Wang C,Zhang S,Yan W,Wang R,Liu J,Wang Y

更新日期：2016-11-18 00:00:00

abstract：:There is a need for noninvasive repeatable biomarkers to detect early cancer treatment response and spare non-responders unnecessary morbidities and costs. Here, we introduce three-dimensional (3D) dynamic contrast enhanced ultrasound (DCE-US) perfusion map characterization as inexpensive, bedside and longitudinal ind...

journal_title：Scientific reports

authors： El Kaffas A,Hoogi A,Zhou J,Durot I,Wang H,Rosenberg J,Tseng A,Sagreiya H,Akhbardeh A,Rubin DL,Kamaya A,Hristov D,Willmann JK

更新日期：2020-04-24 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Mougi A

更新日期：2018-08-10 00:00:00

abstract：:Agamococcidians are enigmatic and poorly studied parasites of marine invertebrates with unexplored diversity and unclear relationships to other sporozoans such as the human pathogens Plasmodium and Toxoplasma. It is believed that agamococcidians are not capable of sexual reproduction, which is essential for life cycle...

journal_title：Scientific reports

authors： Miroliubova TS,Simdyanov TG,Mikhailov KV,Aleoshin VV,Janouškovec J,Belova PA,Paskerova GG

更新日期：2020-09-28 00:00:00

abstract：:There is a pressing need for novel and innovative therapeutic strategies to address infections caused by intracellular pathogens. Peptide nucleic acids (PNAs) present a novel method to target intracellular pathogens due to their unique mechanism of action and their ability to be conjugated to cell penetrating peptides...

journal_title：Scientific reports

authors： Abushahba MF,Mohammad H,Thangamani S,Hussein AA,Seleem MN

更新日期：2016-02-10 00:00:00

abstract：:Amyloid-β (Aβ) deposition is known to starts decades before the onset of clinical symptoms of Alzheimer's disease (AD), however, the detailed pathophysiological processes underlying this preclinical period are not well understood. This study aimed to investigate functional network alterations in cognitively intact eld...

journal_title：Scientific reports

authors： Nakamura A,Cuesta P,Kato T,Arahata Y,Iwata K,Yamagishi M,Kuratsubo I,Kato K,Bundo M,Diers K,Fernández A,Maestú F,Ito K

更新日期：2017-07-26 00:00:00

abstract：:Graphene, a two-dimensional structure of carbon, due to its structure has unique physico-chemical properties that can be used in numerous research and industry areas. Although this structure is already well known, there are still technological (and cost) barriers which do not allow to produce this material in large qu...

journal_title：Scientific reports

authors： Głuchowski P,Tomala R,Jeżowski A,Szewczyk D,Macalik B,Smolina I,Kurzynowski T,Stręk W

更新日期：2020-07-06 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) plays a crucial role in breakdown of the blood-retinal barrier due to hyperpermeability in diabetic retinopathy (DR). However, the distinct signaling driven by VEGF and PlGF in the pathogenesis of DR remains unclear. In this study, we investi...

journal_title：Scientific reports

authors： Jiao W,Ji JF,Xu W,Bu W,Zheng Y,Ma A,Zhao B,Fan Q

更新日期：2019-10-25 00:00:00

abstract：:Utilization of computational approach in the study of social behaviour of animals is increasing and we attempted such an approach in our study of tree-dwelling bats. These bats live in highly dynamic fission-fusion societies that share multiple roosts in a common home range. The key behavioural component associated wi...

journal_title：Scientific reports

authors： Zelenka J,Kasanický T,Budinská I,Kaňuch P

更新日期：2020-10-08 00:00:00

abstract：:In the present work, a catalyst-free physical vapour deposition method is used to synthesize high yield of Bi2Se3 nanoribbons. By replacing standard glass or quartz substrates with aluminium covered with ultrathin porous anodized aluminium oxide (AAO), the number of synthesized nanoribbons per unit area can be increas...

journal_title：Scientific reports

authors： Kunakova G,Meija R,Andzane J,Malinovskis U,Petersons G,Baitimirova M,Bechelany M,Bauch T,Lombardi F,Erts D

更新日期：2019-08-05 00:00:00

abstract：:We compared commercial kits for extraction of genomic DNA from the Gram-negative bacterium Klebsiella pneumoniae for subsequent Miseq sequencing. Purification of DNA was based on matrix binding (silica or anion exchange resin) or differential precipitation (salting out), respectively. The choice of extraction kit had ...

journal_title：Scientific reports

authors： Becker L,Steglich M,Fuchs S,Werner G,Nübel U

更新日期：2016-06-17 00:00:00

abstract：:Heating on the microscale using focused lasers gave rise to recent applications, e.g., in biomedicine, biology and microfluidics, especially using gold nanoparticles as efficient nanoabsorbers of light. However, such an approach naturally leads to nonuniform, Gaussian-like temperature distributions due to the diffusiv...

journal_title：Scientific reports

authors： Durdevic L,Robert HML,Wattellier B,Monneret S,Baffou G

更新日期：2019-03-15 00:00:00

abstract：:Thyroid nodules can be classified into benign and malignant tumors. However, distinguishing between these two types of tumors can be challenging in clinics. Since malignant nodules require surgical intervention whereas asymptomatic benign tumors do not, there is an urgent need for new techniques that enable accurate d...

journal_title：Scientific reports

authors： Tian Y,Nie X,Xu S,Li Y,Huang T,Tang H,Wang Y

更新日期：2015-10-21 00:00:00

abstract：:From the 1950s, the Po delta, one of the largest anthropogenic world deltas, has been subjected to a fast degradation and shoreline retreat due a marked reduction of sediment supply, mainly controlled by human impacts/factors, including subsidence. Through the interpretation of satellite images, coupled with the analy...

journal_title：Scientific reports

authors： Ninfo A,Ciavola P,Billi P

更新日期：2018-02-22 00:00:00

abstract：:Boiling histotripsy (BH) is a High Intensity Focused Ultrasound (HIFU) method for precise mechanical disintegration of target tissue using millisecond-long pulses containing shocks. BH treatments with real-time ultrasound (US) guidance allowed by BH-generated bubbles were previously demonstrated ex vivo and in vivo in...

journal_title：Scientific reports

authors： Khokhlova TD,Schade GR,Wang YN,Buravkov SV,Chernikov VP,Simon JC,Starr F,Maxwell AD,Bailey MR,Kreider W,Khokhlova VA

更新日期：2019-12-27 00:00:00

abstract：:Biomarkers reflecting the extent of Mycobacterium tuberculosis-induced pathology and normalization during anti-tuberculosis treatment (ATT) would considerably facilitate trials of new treatment regimens and the identification of patients with treatment failure. Therefore, in a cohort of 99 Indian children with intrath...

journal_title：Scientific reports

authors： Jenum S,Bakken R,Dhanasekaran S,Mukherjee A,Lodha R,Singh S,Singh V,Haks MC,Ottenhoff TH,Kabra SK,Doherty TM,Ritz C,Grewal HM

更新日期：2016-12-12 00:00:00

abstract：:CD4(+)CD25(+) T cells are critical for maintenance of immunologic self-tolerance. We measured the number of CD4(+)CD25(+) cells in the patients with primary malignant hypertension related kidney injury, to explore the molecular pathogenesis of this disease. We selected 30 patients with primary malignant hypertension r...

journal_title：Scientific reports

authors： Huang H,Luo Y,Liang Y,Long X,Peng Y,Liu Z,Wen X,Jia M,Tian R,Bai C,Li C,He F,Lin Q,Wang X,Dong X

更新日期：2016-06-09 00:00:00

abstract：:Caffeine modifies vascular/cardiac contractility. Embryonic exposure to caffeine altered cardiac functions in offspring. This study determined chronic influence of prenatal caffeine on vessel functions in offspring. Pregnant Sprague-Dawley rats (5-month-old) were exposed to high dose of caffeine, their offspring (5-mo...

journal_title：Scientific reports

authors： Li N,Li Y,Gao Q,Li D,Tang J,Sun M,Zhang P,Liu B,Mao C,Xu Z

更新日期：2015-08-17 00:00:00

abstract：:Quantum Key Distribution is carving its place among the tools used to secure communications. While a difficult technology, it enjoys benefits that set it apart from the rest, the most prominent is its provable security based on the laws of physics. QKD requires not only the mastering of signals at the quantum level, b...

journal_title：Scientific reports

authors： Martinez-Mateo J,Elkouss D,Martin V

更新日期：2013-01-01 00:00:00

abstract：:A spontaneous exchange bias (SEB) discovered by Wang et al. [Phys. Rev. Lett. 106 (2011) 077203.] after zero-field cooling (ZFC) has attracted recent attention due to its interesting physics. In this letter, we report a giant SEB tuned by Sb-doping in Ni50Mn38Ga12-xSbx Heusler alloys. Such an SEB was switched on below...

journal_title：Scientific reports

authors： Tian F,Cao K,Zhang Y,Zeng Y,Zhang R,Chang T,Zhou C,Xu M,Song X,Yang S

更新日期：2016-08-01 00:00:00

abstract：:Caspase-1, also known as interleukin-1β (IL-1β)-converting enzyme (ICE), regulates antimicrobial host defense, tissue repair, tumorigenesis, metabolism and membrane biogenesis. On activation within an inflammasome complex, caspase-1 induces pyroptosis and converts pro-IL-1β and pro-IL-18 into their biologically active...

journal_title：Scientific reports

authors： Man SM,Karki R,Briard B,Burton A,Gingras S,Pelletier S,Kanneganti TD

更新日期：2017-03-27 00:00:00

abstract：:Bisphenol A (BPA) is widely used in the manufacture of plastics and epoxy resins and is prevalent in the aquatic environment. BPA disrupts endocrine pathways in fish, but the long-term developmental implications are unknown. We demonstrate that BPA deposition in the eggs of rainbow trout (Oncorhynchus mykiss), an ecol...

journal_title：Scientific reports

authors： Sadoul B,Birceanu O,Aluru N,Thomas JK,Vijayan MM

更新日期：2017-10-26 00:00:00

abstract：:We evaluated the effect of separately adding two sources of lanthanum (La), LaCl3 and La(NO3)3 × 6H2O at a concentration of 40 µM each, to the preservative solution of 15 cut tulip flower varieties. Ascorbic acid (AsA; 0.2 g/L) was used as a reference solution, while distilled water was used as control. The variety La...

journal_title：Scientific reports

authors： Gómez-Merino FC,Ramírez-Martínez M,Castillo-González AM,Trejo-Téllez LI

更新日期：2020-03-06 00:00:00

abstract：:How exponentially growing cells maintain size homeostasis is an important fundamental problem. Recent single-cell studies in prokaryotes have uncovered the adder principle, where cells add a fixed size (volume) from birth to division, irrespective of their size at birth. To mechanistically explain the adder principle,...

journal_title：Scientific reports

authors： Ghusinga KR,Vargas-Garcia CA,Singh A

更新日期：2016-07-26 00:00:00