Abstract:
:Biochemical and histopathologic parameters of nephrotoxicity were measured in groups of male Fischer-344 rats after a 2-week, 5-days-a-week schedule of oral administration (0.5 ml/kg) of the following substances: aviation gasoline (grade 100) (AVG), automobile regular unleaded gasoline (ULG) and 2,2,4-trimethylpentane (TMP). Results of renal histopathologic examinations and biochemical parameters were compatible with the following order of increasing nephrotoxicity: ULG less than TMP less than AVG. The high nephrotoxic potential of aviation gasoline may be related to its elevated content in branched hydrocarbons.
journal_name
Toxicol Lettjournal_title
Toxicology lettersauthors
Gérin M,Viau C,Talbot D,Greselin Edoi
10.1016/0378-4274(88)90124-5subject
Has Abstractpub_date
1988-11-01 00:00:00pages
13-9issue
1-2eissn
0378-4274issn
1879-3169pii
0378-4274(88)90124-5journal_volume
44pub_type
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