What will the future hold for artificial organs in the service of assisted reproduction: prospects and considerations.

abstract：:Foodborne disease is one of the most important public health issues worldwide. China faces various and unprecedented challenges in all aspects of the food chain. Data from laboratory-based foodborne disease surveillance systems from 2013 to 2016, as well as different regions and ages, can be found along with differenc...

journal_title：Frontiers of medicine

authors： Liu J,Bai L,Li W,Han H,Fu P,Ma X,Bi Z,Yang X,Zhang X,Zhen S,Deng X,Liu X,Guo Y

更新日期：2018-02-01 00:00:00

abstract：:Ventricular hypertrophy is a powerful and independent predictor of cardiovascular morbid events. The vascular properties of low-dose acetyl salicylic acid (aspirin) provide cardiovascular benefits through the irreversible inhibition of platelet cyclooxygenase 1; however, the possible anti-hypertrophic properties and p...

journal_title：Frontiers of medicine

authors： Gitau SC,Li X,Zhao D,Guo Z,Liang H,Qian M,Lv L,Li T,Xu B,Wang Z,Zhang Y,Xu C,Lu Y,Du Z,Shan H,Yang B

更新日期：2015-12-01 00:00:00

abstract：:We observed the effect of Dianxianning, which was used as additive treatment to treat 206 epilepsy patients, on the epilepsy seizure rate. Based on a multicenter, prospective, randomized, and controlled clinical trial design, we used the seizure rate of epilepsy as the main index. For the treatment group comprising 13...

journal_title：Frontiers of medicine

authors： He L,Wen T,Yan S,Li R,Liu Z,Ren H,Liu J,Zhang F,Wu J,Liu J

更新日期：2011-06-01 00:00:00

abstract：:γδ T cells display unique developmental, distributional, and functional patterns and can rapidly respond to various insults and contribute to diverse diseases. Different subtypes of γδ T cells are produced in the thymus prior to their migration to peripheral tissues. γδ T cells are enriched in the liver and exhibit li...

journal_title：Frontiers of medicine

authors： Wang X,Tian Z

更新日期：2018-06-01 00:00:00

abstract：:A phase II study (A2202) was performed to evaluate the efficacy and safety of JAK inhibitor ruxolitinib in 63 Chinese MF patients. Ruxolitinib was given twice a day (bid) at a starting dose of 15 mg (n = 25) or 20 mg (n = 38) based on a baseline platelet count. About 94.7% of the patients achieved a reduction in splee...

journal_title：Frontiers of medicine

authors： Du X,Zhou D

更新日期：2016-12-01 00:00:00

abstract：:This study aimed to evaluate the efficacy of Chinese herbal medicine (CHM) in patients with severe/critical coronavirus disease 2019 (COVID-19). In this retrospective study, data were collected from 662 patients with severe/critical COVID-19 who were admitted to a designated hospital to treat patients with severe COVI...

journal_title：Frontiers of medicine

authors： Chen G,Su W,Yang J,Luo D,Xia P,Jia W,Li X,Wang C,Lang S,Meng Q,Zhang Y,Ke Y,Fan A,Yang S,Zheng Y,Fan X,Qiao J,Lian F,Wei L,Tong X

更新日期：2020-12-01 00:00:00

abstract：:It is well documented that patients can show significant heterogeneous responses to treatments so the best treatment strategies may require adaptation over individuals and time. Recently, a number of new statistical methods have been developed to tackle the important problem of estimating personalized treatment rules ...

journal_title：Frontiers of medicine

authors： Zhao Y,Zeng D

更新日期：2013-03-01 00:00:00

abstract：:As a promising method in artificial intelligence, deep learning has been proven successful in several domains ranging from acoustics and images to natural language processing. With medical imaging becoming an important part of disease screening and diagnosis, deep learning-based approaches have emerged as powerful tec...

journal_title：Frontiers of medicine

authors： Ma J,Song Y,Tian X,Hua Y,Zhang R,Wu J

更新日期：2020-08-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is currently the fifth most common malignancy and the third leading cause of cancer-related mortalities worldwide. In the last few years, treatments for HCC have significantly improved from a mere surgical resection to a series of minimally invasive therapies and targeted drugs. However,...

journal_title：Frontiers of medicine

authors： Yu M,Li Z

更新日期：2017-12-01 00:00:00

abstract：:Grading of Recommendations Assessment, Development, and Evaluation (GRADE) offers a worldwide approach to guideline development for clinical practice. For the clinical practice of acupuncture therapy, 18 evidence-based guidelines have been developed in China using GRADE. In this study, we review the advantages and lim...

journal_title：Frontiers of medicine

authors： Zhao H,Liang F,Fang Y,Liu B

更新日期：2017-12-01 00:00:00

abstract：:An effective eradication therapy of Helicobacter pylori (H. pylori) should be used for the first time. In this study, we assessed whether tailored therapy based on antibiotic susceptibility testing is more effective than traditional therapy. We also evaluated the factors that cause treatment failure in high-resistance...

journal_title：Frontiers of medicine

authors： Pan J,Shi Z,Lin D,Yang N,Meng F,Lin L,Jin Z,Zhou Q,Wu J,Zhang J,Li Y

更新日期：2020-02-01 00:00:00

abstract：:A high level of social support can improve long-term diabetes self-management. Support from a single source has been evaluated. This study aims to analyze support from multiple and multilevel sources for diabetic patients by using the Chronic Illness Resources Survey (CIRS). Factors influencing the utilization of the ...

journal_title：Frontiers of medicine

authors： Zhong H,Shao Y,Fan L,Zhong T,Ren L,Wang Y

更新日期：2016-06-01 00:00:00

abstract：:Antitumor angiogenic therapy has been shown promising in the treatment of several advanced cancers since the approval of the first antiangiogenic drug Avastin in 2004. Although the current antiangiogenic drugs reduce the density of tumor blood vessels and result in tumor shrinkage at the early stage of treatment, rece...

journal_title：Frontiers of medicine

authors： Shang B,Cao Z,Zhou Q

更新日期：2012-03-01 00:00:00

abstract：:The rationale for the antibiotic treatment of viral community-acquired pneumonia (CAP) in adults was analyzed to develop a clinical reference standard for this condition. Clinical data from 166 patients diagnosed with viral pneumonia across 14 hospitals in Beijing from November 2010 to December 2017 were collected. Th...

journal_title：Frontiers of medicine

authors： Jiang R,Han B,Dou C,Zhou F,Cao B,Li X

更新日期：2020-06-13 00:00:00

abstract：:Cleft lip and palate (CLP) is the most common craniofacial congenital deformity. The etiology of CLP is multifactorial and involves complex interactions between environmental and genetic factors. Millard's rotation advancement technique has long been considered as state-of-the-art for unilateral cleft lip repair. Howe...

journal_title：Frontiers of medicine

authors： Xu Y,Li J,Shi B

更新日期：2013-12-01 00:00:00

abstract：:Tissue factor pathway inhibitor (TFPI) is the main inhibitor of tissue factor-mediated coagulation. TFPI is expressed by endothelial and smooth muscle cells in the vasculature. Endothelium-derived TFPI has been reported to play a regulatory role in arterial thrombosis. However, the role of endogenous TFPI in vascular ...

journal_title：Frontiers of medicine

authors： Yang J,Jin K,Xiao J,Ma J,Ma D

更新日期：2017-09-01 00:00:00

abstract：:The teeth are highly differentiated chewing organs formed by the development of tooth germ tissue located in the jaw and consist of the enamel, dentin, cementum, pulp, and periodontal tissue. Moreover, the teeth have a complicated regulatory mechanism, special histologic origin, diverse structure, and important functi...

journal_title：Frontiers of medicine

authors： Zhai Q,Dong Z,Wang W,Li B,Jin Y

更新日期：2019-04-01 00:00:00

abstract：:The ongoing pandemic of Coronavirus disease 19 (COVID-19) is caused by a newly discovered β Coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). How long the adaptive immunity triggered by SARS-CoV-2 can last is of critical clinical relevance in assessing the probability of second infection ...

journal_title：Frontiers of medicine

authors： Tan Y,Liu F,Xu X,Ling Y,Huang W,Zhu Z,Guo M,Lin Y,Fu Z,Liang D,Zhang T,Fan J,Xu M,Lu H,Chen S

更新日期：2020-12-01 00:00:00

abstract：:The prevalence of the risk factors and the risk of cardiac failure are both increasing in China. This might be the consequence of the changes of the life conditions (emigration to the urban areas, changes in the diet and life style, lack of physical exercise, etc.). The wide range of clinical presentations of cardiac ...

journal_title：Frontiers of medicine

authors： Loisance D

更新日期：2011-03-01 00:00:00

abstract：:Identification of the driver mutations in cancer has resulted in the development of a new category of molecularly targeted anti-cancer drugs. However, as was the case with conventional chemotherapies, the effectiveness of these drugs is limited by the emergence of drug-resistant variants. While most cancer therapies a...

journal_title：Frontiers of medicine

authors： Wang L,Bernards R

更新日期：2018-08-01 00:00:00

abstract：:Although type 2 diabetes is a disease often associated with aging, the global prevalence of early-onset diabetes has been increasing due to man's sedentary lifestyle, low-physical activity, obesity, and some nonmodifiable risk factors. Many studies have found that individuals with early-onset type 2 diabetes were at h...

journal_title：Frontiers of medicine

authors： Pan J,Jia W

更新日期：2018-12-01 00:00:00

abstract：:This study evaluated the immunogenicity and protective immunity of a Hemophilus influenzae b (Hib) polysaccharide conjugate vaccine with the pneumococcal surface adhesin A (PsaA) protein carrier in young mice. The Hib polysaccharide was conjugated with the rPsaA protein carrier, which was produced using recombinant DN...

journal_title：Frontiers of medicine

authors： Chen Z,Guo R,Xu J,Qiu C

更新日期：2016-12-01 00:00:00

abstract：:Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as an important respiratory disease with high fatality rates of 40%-60%. Despite the increased number of cases over subsequent years, the number of pediatric cases remained low. A review of studies conducted from June 2012 to April ...

journal_title：Frontiers of medicine

authors： Alfaraj SH,Al-Tawfiq JA,Altuwaijri TA,Memish ZA

更新日期：2019-02-01 00:00:00

abstract：:Real world study (RWS) has become a hotspot for clinical research. Data quality plays a vital role in research achievement and other clinical research fields. In this paper, the common quality problems in the RWS of traditional Chinese medicine are discussed, and a countermeasure is proposed. ...

journal_title：Frontiers of medicine

authors： Zhang R,Wang Y,Liu B,Song G,Zhou X,Fan S,Pan X

更新日期：2014-09-01 00:00:00

abstract：:Netrin-1 (NT-1) is one of the axon-guiding molecules that are critical for neuronal development. Because of its structural homology to the endothelial mitogens, NT-1 may have similar effects on vascular network formation. NT-1 was shown to be able to stimulate the proliferation and migration of human cerebral endothel...

journal_title：Frontiers of medicine

authors： Lu H,Wang Y,Yuan F,Liu J,Zeng L,Yang GY

更新日期：2011-03-01 00:00:00

abstract：:Electroacupuncture (EA) at Zhongliao (BL33) can improve the symptoms of overactive bladder (OAB), such as urinary frequency, urgency, and incontinence. However, its performance compared with other acupoints remains unclear. This study investigated the effects of EA at BL33 with deep needling on rats with OAB by detect...

journal_title：Frontiers of medicine

authors： Yang L,Wang Y,Mo Q,Liu Z

更新日期：2017-03-01 00:00:00

abstract：:MicroRNAs (miRNAs), an important class of small non-coding RNAs, regulate gene expression at the post-transcriptional level. miRNAs are involved in a wide range of biological processes and implicated in different diseases, including cancers. In this study, miRNA profiling and qRT-PCR validation revealed that miR-142-3...

journal_title：Frontiers of medicine

authors： Tsang FH,Au SL,Wei L,Fan DN,Lee JM,Wong CC,Ng IO,Wong CM

更新日期：2015-09-01 00:00:00

abstract：:Sickle cell disease (SCD) is an inherited disorder of hemoglobin in which the abnormal hemoglobin S polymerizes when deoxygenated. This polymerization of hemoglobin S not only results in hemolysis and vasoocclusion but also precipitates inflammation, oxidative stress and chronic organ dysfunction. Oxidative stress is ...

journal_title：Frontiers of medicine

authors： Owusu-Ansah A,Choi SH,Petrosiute A,Letterio JJ,Huang AY

更新日期：2015-03-01 00:00:00

abstract：:This study aimed to explore the association of maternal depression with nutrient intake, growth, and development of preterm infants. A cohort study of 201 infants was conducted in Beijing. Based on the gestational age of an infant and status of the mother, the infants were divided into four groups: non-depression-full...

journal_title：Frontiers of medicine

authors： Wang H,Zhou H,Zhang Y,Wang Y,Sun J

更新日期：2018-10-01 00:00:00

abstract：:Laparoscopic liver surgery has been increasingly used for the treatment of pediatric liver diseases over the past decade due to the development of special laparoscopic instruments and improvements in the technique. A number of factors are considered when electing to undergo the surgical process, including age, type of...

journal_title：Frontiers of medicine

authors： Wei J,Feng J

更新日期：2011-12-01 00:00:00