Abstract:
:Laparoscopic liver surgery has been increasingly used for the treatment of pediatric liver diseases over the past decade due to the development of special laparoscopic instruments and improvements in the technique. A number of factors are considered when electing to undergo the surgical process, including age, type of liver disease, and so on. Especially in children with liver masses, the number of trocars used and the position of their placement must be carefully designed to achieve successful outcomes. In the current review, the application of various laparoscopic instruments and the methods used for the laparoscopic treatment of liver diseases in children over the past decade are summarized.
journal_name
Front Medjournal_title
Frontiers of medicineauthors
Wei J,Feng Jdoi
10.1007/s11684-011-0165-3subject
Has Abstractpub_date
2011-12-01 00:00:00pages
388-94issue
4eissn
2095-0217issn
2095-0225journal_volume
5pub_type
杂志文章,评审abstract::A phase II study (A2202) was performed to evaluate the efficacy and safety of JAK inhibitor ruxolitinib in 63 Chinese MF patients. Ruxolitinib was given twice a day (bid) at a starting dose of 15 mg (n = 25) or 20 mg (n = 38) based on a baseline platelet count. About 94.7% of the patients achieved a reduction in splee...
journal_title:Frontiers of medicine
pub_type: 杂志文章,多中心研究
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abstract::γδ T cells display unique developmental, distributional, and functional patterns and can rapidly respond to various insults and contribute to diverse diseases. Different subtypes of γδ T cells are produced in the thymus prior to their migration to peripheral tissues. γδ T cells are enriched in the liver and exhibit li...
journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
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abstract::Ventricular hypertrophy is a powerful and independent predictor of cardiovascular morbid events. The vascular properties of low-dose acetyl salicylic acid (aspirin) provide cardiovascular benefits through the irreversible inhibition of platelet cyclooxygenase 1; however, the possible anti-hypertrophic properties and p...
journal_title:Frontiers of medicine
pub_type: 杂志文章
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abstract::This study aimed to explore the association of maternal depression with nutrient intake, growth, and development of preterm infants. A cohort study of 201 infants was conducted in Beijing. Based on the gestational age of an infant and status of the mother, the infants were divided into four groups: non-depression-full...
journal_title:Frontiers of medicine
pub_type: 杂志文章
doi:10.1007/s11684-017-0591-y
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abstract::Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as an important respiratory disease with high fatality rates of 40%-60%. Despite the increased number of cases over subsequent years, the number of pediatric cases remained low. A review of studies conducted from June 2012 to April ...
journal_title:Frontiers of medicine
pub_type: 杂志文章
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更新日期:2019-02-01 00:00:00
abstract::The mammalian MOF (male absent on the first), a member of the MYST (MOZ, YBF2, SAS2, and Tip60) family of histone acetyltransferases (HATs), is the major enzyme that catalyzes the acetylation of histone H4 on lysine 16. Acetylation of K16 is a prevalent mark associated with chromatin decondensation. MOF has recently b...
journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
doi:10.1007/s11684-014-0314-6
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abstract::This study aimed to compare the antimicrobial activities of topical agents against Propionibacterium acnes isolated from patients admitted to a hospital in Shanghai, China. The minimal inhibitory concentrations of the cultured P. acnes were determined in accordance with the Clinical and Laboratory Standards Institute....
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pub_type: 杂志文章,随机对照试验
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更新日期:2016-12-01 00:00:00
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journal_title:Frontiers of medicine
pub_type: 杂志文章
doi:10.1007/s11684-015-0417-8
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abstract::Inappropriate cell proliferation during oncogenesis is often accompanied by inactivation of components involved in the cell cycle machinery. Here, we report that cyclin-dependent kinase inhibitor 2C (CDKN2C) as a member of the cyclin-dependent kinase inhibitors is a target of the PML/RARα oncofusion protein in leukemo...
journal_title:Frontiers of medicine
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journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
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abstract::S100A9, a calcium-binding protein, participates in the inflammatory process and development of various tumors, thus attracting much attention in the field of cancer biology. This study aimed to investigate the regulatory mechanism of S100A9 and its function involvement in APL. We used real-time quantitative PCR to det...
journal_title:Frontiers of medicine
pub_type: 杂志文章
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abstract::It has been known that, the novel coronavirus, 2019-nCoV, which is considered similar to SARS-CoV, invades human cells via the receptor angiotensin converting enzyme II (ACE2). Moreover, lung cells that have ACE2 expression may be the main target cells during 2019-nCoV infection. However, some patients also exhibit no...
journal_title:Frontiers of medicine
pub_type: 杂志文章
doi:10.1007/s11684-020-0754-0
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abstract::The rationale for the antibiotic treatment of viral community-acquired pneumonia (CAP) in adults was analyzed to develop a clinical reference standard for this condition. Clinical data from 166 patients diagnosed with viral pneumonia across 14 hospitals in Beijing from November 2010 to December 2017 were collected. Th...
journal_title:Frontiers of medicine
pub_type: 杂志文章
doi:10.1007/s11684-019-0736-2
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abstract::Obstructive sleep apnea syndrome (OSAS) increases the risk of post-surgery complications. This study uses Berlin Questionnaire (BQ) to identify Chinese adult surgical patients who are at a high risk of OSAS and to determine if the BQ could be used to detect potential high risk of adverse respiratory events in the post...
journal_title:Frontiers of medicine
pub_type: 杂志文章
doi:10.1007/s11684-017-0533-8
更新日期:2018-04-01 00:00:00
abstract::Alternative splicing plays a fundamental role in the development and physiological function of the inner ear. Inner-ear-specific gene splicing is necessary to establish the identity and maintain the function of the inner ear. For example, exon 68 of Cadherin 23 (Cdh23) gene is subject to inner-ear-specific alternative...
journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
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abstract::Antitumor angiogenic therapy has been shown promising in the treatment of several advanced cancers since the approval of the first antiangiogenic drug Avastin in 2004. Although the current antiangiogenic drugs reduce the density of tumor blood vessels and result in tumor shrinkage at the early stage of treatment, rece...
journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
doi:10.1007/s11684-012-0176-8
更新日期:2012-03-01 00:00:00
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journal_title:Frontiers of medicine
pub_type: 杂志文章
doi:10.1007/s11684-016-0489-0
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journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
doi:10.1007/s11684-013-0251-9
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pub_type: 杂志文章,评审
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journal_title:Frontiers of medicine
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journal_title:Frontiers of medicine
pub_type: 杂志文章
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journal_title:Frontiers of medicine
pub_type: 杂志文章
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abstract::Our preliminary studies demonstrated that Metacavir has potential to become a new anti-HBV agent. The main targets of the toxic effects of Metacavir, in rhesus monkeys, were gastrointestinal tracts, liver, blood, and kidneys, which were not related to mitochondrial effects. In this study, the maternal toxicity, embryo...
journal_title:Frontiers of medicine
pub_type: 杂志文章
doi:10.1007/s11684-015-0376-0
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abstract::Assisted reproduction provides a wide spectrum of treatments and strategies addressing infertility. However, distinct groups of infertile patients with unexplained infertility, congenital disorders, and other complex cases pose a challenge in in vitro fertilization (IVF) practices. This special cohort of patients is a...
journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
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abstract::Gliomas are the most common primary intracranial tumors in adults. Anaplastic gliomas (WHO grade III) and glioblastomas (WHO grade IV) represent the major groups of malignant gliomas in the brain. Several diagnostic, predictive, and prognostic biomarkers for malignant gliomas have been reported over the last few decad...
journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
doi:10.1007/s11684-013-0267-1
更新日期:2013-06-01 00:00:00
abstract::As a promising method in artificial intelligence, deep learning has been proven successful in several domains ranging from acoustics and images to natural language processing. With medical imaging becoming an important part of disease screening and diagnosis, deep learning-based approaches have emerged as powerful tec...
journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
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abstract::Zebrafish is an emerging animal model for studies on auditory system. This model presents high comparability with humans, good accessibility to the hearing organ, and high throughput capacity. To better utilize this animal model, methodologies need to be used to quantify the hearing function of the zebrafish. Zebrafis...
journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
doi:10.1007/s11684-017-0507-x
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abstract::This study aimed to evaluate the efficacy of comprehensive therapy based on traditional Chinese medicine (TCM) patterns on older patients with chronic obstructive pulmonary disease (COPD) through a fourcenter, open-label, randomized controlled trial. Patients were divided into the trial group treated using conventiona...
journal_title:Frontiers of medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s11684-014-0360-0
更新日期:2014-09-01 00:00:00
abstract::Hearing impairment is considered as the most prevalent impairment worldwide. Almost 600 million people in the world suffer from mild or moderate hearing impairment, an estimated 10% of the human population. Genetic factors play an important role in the pathogenesis of this disorder. Hereditary hearing loss is divided ...
journal_title:Frontiers of medicine
pub_type: 杂志文章,评审
doi:10.1007/s11684-016-0449-8
更新日期:2016-06-01 00:00:00