Abstract：
:This study aimed to evaluate the efficacy of comprehensive therapy based on traditional Chinese medicine (TCM) patterns on older patients with chronic obstructive pulmonary disease (COPD) through a fourcenter, open-label, randomized controlled trial. Patients were divided into the trial group treated using conventional western medicine and Bu-Fei Jian-Pi granules, Bu-Fei Yi-Shen granules, and Yi-Qi Zi-Shen granules based on TCM patterns respectively; and the control group treated using conventional western medicine. A total of 136 patients ≥ 65 years completed the study, with 63 patients comprising the trial group and 73 comprising the control group. After the six-month treatment and the 12-month follow-up period, significant differences were observed between the trial and control groups in the following aspects: frequency of acute exacerbation (P ≤ 0.040), duration of acute exacerbation (P = 0.034), symptoms (P ≤ 0.034), 6-min walking distance (6MWD) (P ≤ 0.039), dyspnea scale (P ≤ 0.036); physical domain (P ≤ 0.019), psychological domain (P ≤ 0.033), social domain (P ≤ 0.020), and environmental domain (P ≤ 0.044) of the WHOQOL-BREF questionnaire; and daily living ability domain (P ≤ 0.007), social activity domain (P ≤ 0.018), depression symptoms domain (P ≤ 0.025), and anxiety symptoms domain (P ≤ 0.037) of the COPD-QOL. No differences were observed between the trial and control groups with regard to FVC, FEV1, and FEV1%.
journal_name
Front Medjournal_title
Frontiers of medicineauthors
Wang M,Li J,Li S,Xie Ydoi
10.1007/s11684-014-0360-0subject
Has Abstractpub_date
2014-09-01 00:00:00pages
368-75issue
3eissn
2095-0217issn
2095-0225journal_volume
8pub_type
杂志文章,多中心研究,随机对照试验abstract：:Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as an important respiratory disease with high fatality rates of 40%-60%. Despite the increased number of cases over subsequent years, the number of pediatric cases remained low. A review of studies conducted from June 2012 to April ...
journal_title：Frontiers of medicine
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abstract：:Childhood obesity and obesity-related metabolic complications are induced by a high-fat postnatal diet. The lack of a suitable animal model, however, remains a considerable challenge in obesity studies. In the current study, we provided high-fat diet (HFD) to dams during lactation and to pups after weaning. We also de...
journal_title：Frontiers of medicine
pub_type： 杂志文章
doi：10.1007/s11684-017-0530-y
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abstract：:This study aimed to define the most consistent white matter microarchitecture pattern in Parkinson's disease (PD) reflected by fractional anisotropy (FA), addressing clinical profiles and methodology-related heterogeneity. Web-based publication databases were searched to conduct a meta-analysis of whole-brain diffusio...
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pub_type： 杂志文章,评审
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abstract：:Transforming growth factor (TGF)-β regulates a wide variety of cellular responses, including cell growth arrest, apoptosis, cell differentiation, motility, invasion, extracellular matrix production, tissue fibrosis, angiogenesis, and immune function. Although tumor-suppressive roles of TGF-β have been extensively stud...
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pub_type： 杂志文章,评审
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abstract：:The ongoing pandemic of Coronavirus disease 19 (COVID-19) is caused by a newly discovered β Coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). How long the adaptive immunity triggered by SARS-CoV-2 can last is of critical clinical relevance in assessing the probability of second infection ...
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abstract：:Although many drugs and therapeutic strategies have been developed for rheumatoid arthritis (RA) treatment, numerous patients with RA fail to respond to currently available agents. In this review, we provide an overview of the complexity of this autoimmune disease by showing the rapidly increasing number of genes asso...
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pub_type： 杂志文章,评审
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journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
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更新日期：2011-12-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2019-04-01 00:00:00
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更新日期：2019-02-01 00:00:00
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journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
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更新日期：2012-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：2014-03-01 00:00:00
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更新日期：2017-03-01 00:00:00
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更新日期：2011-03-01 00:00:00
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pub_type： 杂志文章,评审
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pub_type： 杂志文章,评审
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journal_title：Frontiers of medicine
pub_type： 杂志文章,meta分析
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pub_type： 杂志文章
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journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
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pub_type： 杂志文章,多中心研究
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更新日期：2020-02-01 00:00:00
