Abstract：
:This study aimed to compare the antimicrobial activities of topical agents against Propionibacterium acnes isolated from patients admitted to a hospital in Shanghai, China. The minimal inhibitory concentrations of the cultured P. acnes were determined in accordance with the Clinical and Laboratory Standards Institute. Susceptibilities to clindamycin and erythromycin were compared in terms of gender, age, disease duration, previous treatment, and disease severity. A total of 69 P. acnes strains were isolated from 98 patients (70.41%). The susceptibility to triple antibiotic ointment (neomycin/bacitracin/polymyxin B) and bacitracin was 100%. The susceptibility to fusidic acid was 92.7%. The resistance rates to neomycin sulfate, erythromycin, and clindamycin were 11.7%, 49.3%, and 33.4%, respectively. The high resistance rate to clindamycin and erythromycin was significantly affected by gender, previous treatment, and disease severity rather than by age and disease duration. Topical antibiotics should not be used separately for long-term therapy to avoid multiresistance. The use of topical antibiotics should be determined by clinicians on the basis of clinical conditions.
journal_name
Front Medjournal_title
Frontiers of medicineauthors
Ma Y,Zhang N,Wu S,Huang H,Cao Ydoi
10.1007/s11684-016-0480-9subject
Has Abstractpub_date
2016-12-01 00:00:00pages
517-521issue
4eissn
2095-0217issn
2095-0225pii
10.1007/s11684-016-0480-9journal_volume
10pub_type
杂志文章,随机对照试验abstract：:The COVID-19 caused by a novel strain of coronavirus has been spreading rapidly since its occurrence in December 2019. It is highly communicable through human-to-human transmission. China has been making unprecedented efforts in treating the confirmed cases, identifying and isolating their close contacts and suspected...
journal_title：Frontiers of medicine
pub_type： 杂志文章
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journal_title：Frontiers of medicine
pub_type： 杂志文章
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abstract：:Chromosomal aberrations have been associated with cancer development since their discovery more than a hundred years ago. Chromosomal translocations, a type of particular structural changes involving heterologous chromosomes, have made a critical impact on diagnosis, prognosis and treatment of cancers. For example, th...
journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
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journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
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journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
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abstract：:Perioperative parecoxib administration reduces postoperative pain, opioid consumption, and adverse events in adult patients. However, the efficacy and safety of parecoxib in children remain unclear. This metaanalysis included related published studies to address this concern. Eight databases in the literature until Fe...
journal_title：Frontiers of medicine
pub_type： 杂志文章,meta分析
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pub_type： 杂志文章
doi：10.1007/s11684-016-0461-z
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journal_title：Frontiers of medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/s11684-016-0441-3
更新日期：2016-06-01 00:00:00
abstract：:An effective eradication therapy of Helicobacter pylori (H. pylori) should be used for the first time. In this study, we assessed whether tailored therapy based on antibiotic susceptibility testing is more effective than traditional therapy. We also evaluated the factors that cause treatment failure in high-resistance...
journal_title：Frontiers of medicine
pub_type： 杂志文章,多中心研究,随机对照试验
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pub_type： 杂志文章
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更新日期：2019-10-01 00:00:00
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pub_type： 杂志文章,评审
doi：10.1007/s11684-018-0628-x
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pub_type： 杂志文章
doi：10.1007/s11684-018-0647-7
更新日期：2018-08-01 00:00:00
abstract：:Inappropriate cell proliferation during oncogenesis is often accompanied by inactivation of components involved in the cell cycle machinery. Here, we report that cyclin-dependent kinase inhibitor 2C (CDKN2C) as a member of the cyclin-dependent kinase inhibitors is a target of the PML/RARα oncofusion protein in leukemo...
journal_title：Frontiers of medicine
pub_type： 杂志文章
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journal_title：Frontiers of medicine
pub_type： 杂志文章,多中心研究,随机对照试验
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pub_type： 杂志文章,评审
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pub_type： 杂志文章,评审
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pub_type： 杂志文章
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journal_title：Frontiers of medicine
pub_type： 杂志文章
doi：10.1007/s11684-011-0118-x
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journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
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journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
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pub_type： 杂志文章
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journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
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journal_title：Frontiers of medicine
pub_type： 杂志文章
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journal_title：Frontiers of medicine
pub_type： 杂志文章,评审
doi：10.1007/s11684-018-0646-8
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