Abstract:
:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Yan FF,Hou F,Lu ZL,Hu X,Huang CBdoi
10.1038/s41598-019-42527-wsubject
Has Abstractpub_date
2019-04-12 00:00:00pages
6240issue
1issn
2045-2322pii
10.1038/s41598-019-42527-wjournal_volume
9pub_type
已发布勘误abstract::Foot-and-mouth disease (FMD) is a highly contagious disease of livestock affecting animal production and trade throughout Asia and Africa. Understanding FMD virus (FMDV) global movements and evolution can help to reconstruct the disease spread between endemic regions and predict the risks of incursion into FMD-free co...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32693-8
更新日期:2018-10-02 00:00:00
abstract::Magnetic-charge ordering and corresponding magnetic/monopole phase transitions in spin ices are the emergent topics of condensed matter physics. In this work, we investigate a series of magnetic-charge (monopole) phase transitions in artificial square spin ice model using the conserved monopole density algorithm. It i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15875
更新日期:2015-10-29 00:00:00
abstract::Mitochondria act as a platform for antiviral innate immunity, and the immune system depends on activation of the retinoic acid-inducible gene I (RIG-I)-like receptors (RLR) signaling pathway via an adaptor molecule, mitochondrial antiviral signaling. We report that RLR-mediated antiviral innate immunity requires oxida...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05808-w
更新日期:2017-07-14 00:00:00
abstract::Partial thrombosis of the false lumen in uncomplicated type B aortic dissection (uTBAD) is associated with an increased late mortality risk. Whether the serum cortisol level can affect false lumen thrombosis in patients with uTBAD has not been well characterized. This study was performed on 87 patients with uTBAD. A c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19691-6
更新日期:2018-01-19 00:00:00
abstract::The expression of legumain which has been shown overexpressed in patients with metastatic gastric cancer is positively correlated to both disease progression and outcome, and negatively correlated to microRNA (miR)-3978 expression. The RNA-binding protein, poly r(C) binding protein 1 (PCBP1) was the most downregulated...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15448-9
更新日期:2017-11-14 00:00:00
abstract::Centromeres usually contain large amounts of tandem repeat DNA. Alpha satellite DNA (AS) is the most abundant tandem repeat DNA found in the centromeres of simian primates. The AS of humans contains sequences organized into higher-order repeat (HOR) structures, which are tandem arrays of larger repeat units consisting...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10315
更新日期:2015-05-14 00:00:00
abstract::Long-read sequencing technologies such as Pacific Biosciences and Oxford Nanopore MinION are capable of producing long sequencing reads with average fragment lengths of over 10,000 base-pairs and maximum lengths reaching 100,000 base- pairs. Compared with short reads, the assemblies obtained from long-read sequencing ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03996-z
更新日期:2017-06-21 00:00:00
abstract::Polysialic acid (PSA) is a large negatively charged glycan mainly attached to the neural cell adhesion molecule (NCAM). Several studies have shown that it is important for correct formation of brain circuitries during development and for synaptic plasticity, learning and memory in the adult. PSA also plays a major rol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26927
更新日期:2016-06-21 00:00:00
abstract::In North America, red blood cells (RBCs) are cryopreserved in a clinical setting using high glycerol concentrations (40% w/v) with slow cooling rates (~1°C/min) prior to storage at -80°C, while European protocols use reduced glycerol concentrations with rapid freezing rates. After thawing and prior to transfusion, gly...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09692
更新日期:2015-04-08 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-28707-0
更新日期:2018-08-07 00:00:00
abstract::Besides clinical characteristics, easy-accessible laboratory markers could be of value to refine risk stratification in peripheral artery disease. In the current study, we investigated whether α-hydroxybutyrate dehydrogenase (HBDH) is associated with atherothrombotic events in 83 stable patients undergoing infrainguin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54899-0
更新日期:2019-12-03 00:00:00
abstract::Up to now, full tunability of waveforms was possible only in electronics, up to radio-frequencies. Here we propose a new concept of producing few-cycle terahertz (THz) pulses with widely tunable waveforms. It is based on control of the phase delay between different parts of the THz wavefront using linear diffractive o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43852-w
更新日期:2019-05-15 00:00:00
abstract::Ruminants obtain nutrients from microbial fermentation of plant material, primarily in their rumen, a multilayered forestomach. How the different layers of the rumen wall respond to diet and influence microbial fermentation, and how these process are regulated, is not well understood. Gene expression correlation netwo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39022
更新日期:2016-12-14 00:00:00
abstract::A better understanding of the mechanisms of action of human adjuvants could inform a rational development of next generation vaccines for human use. Here, we exploited a genome wide transcriptomics analysis combined with a systems biology approach to determine the molecular signatures induced by four clinically tested...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39097
更新日期:2016-12-13 00:00:00
abstract::Untreated pathological cardiac hypertrophy, which can be caused by sustained systemic hypertension, may lead to heart failure. In the present study, we investigated whether AS-1 had attenuating effects on hypertension-induced cardiac hypertrophy, and whether this process was mediated by the regulation of miRNA-143. To...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-42936-x
更新日期:2019-04-23 00:00:00
abstract::Frequency-modulated sounds play an important role in our daily social life. However, it currently remains unclear whether frequency modulation rates affect neural activity in the human auditory cortex. In the present study, using magnetoencephalography, we investigated the auditory evoked N1m and sustained field respo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18143
更新日期:2015-12-14 00:00:00
abstract::The vertical migration of zooplankton and micronekton (hereafter 'zooplankton') has ramifications throughout the food web. Here, we present the first evidence that climate fluctuations affect the vertical migration of zooplankton in the Southern Ocean, based on multi-year acoustic backscatter data from one of the deep...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46423-1
更新日期:2019-07-12 00:00:00
abstract::Liquid foams are classified into a dry foam and a wet foam, empirically judging from the liquid fraction or the shape of the gas bubbles. It is known that physical properties such as elasticity and diffusion are different between the dry foam and the wet foam. Nevertheless, definitions of those states have been vague ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37506
更新日期:2016-11-22 00:00:00
abstract::Appropriate isolation methods are essential for unravelling the relative contribution of extracellular vesicles (EVs) and the EV-free secretome to homeostasis and disease. We hypothesized that ultrafiltration followed by size exclusion chromatography (UF-SEC) provides well-matched concentrates of EVs and free secreted...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15717-7
更新日期:2017-11-10 00:00:00
abstract::Endosymbioses are driving forces underlying cell evolution. The endosymbiosis exhibited by Paramecium bursaria is an excellent model with which to study symbiosis. A single-cell microscopic analysis of P. bursaria reveals that endosymbiont numbers double when the host is in the division phase. Consequently, endosymbio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31638
更新日期:2016-08-17 00:00:00
abstract::Interaction between the epithelium and mesenchyme coordinates patterning and differentiation of oral cavity structures including teeth, palatal rugae and tongue papillae. SHH is one of the key signaling molecules for this interaction. Epithelial expression of Shh in the tooth buds and tongue papillae is regulated by a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12532-y
更新日期:2017-10-11 00:00:00
abstract::To investigate the mechanism underlying AT1-AA-induced retinopathy in severe preeclampsia by measuring the positive rate and titer of AT1-AA in plasma from women with severe preeclampsia and normal pregnant women to see whether AT1-AA titer was correlated with the grade of retinopathy. A preeclampsia rat model was als...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29036
更新日期:2016-07-06 00:00:00
abstract::Published data have shown inconsistent results about the pharmacogenetics of XRCC1 gene on clinical outcomes of advanced lung cancer patients treated with platinum-based chemotherapy. This meta-analysis aimed to summarize published findings and provide more reliable association. A total of 53 eligible studies includin...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/srep16482
更新日期:2015-11-20 00:00:00
abstract::Chronic sleep fragmentation (SF) commonly occurs in human populations, and although it does not involve circadian shifts or sleep deprivation, it markedly alters feeding behaviors ultimately promoting obesity and insulin resistance. These symptoms are known to be related to the host gut microbiota. Mice were exposed t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35405
更新日期:2016-10-14 00:00:00
abstract::A two-dimensional electron gas (2DEG) with equal-strength Rashba and Dresselhaus spin-orbit coupling sustains persistent helical spin-wave states, which have remarkably long lifetimes. In the presence of an in-plane magnetic field, there exist single-particle excitations that have the character of propagating helical ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21818-8
更新日期:2018-02-22 00:00:00
abstract::Despite the fact that 2015 was the international year of light, no mention was made of the fact that radiation contains entropy as well as energy, with different spectral distributions. Whereas the energy function has been vastly studied, the radiation entropy distribution has not been analysed at the same speed. The ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01622-6
更新日期:2017-05-10 00:00:00
abstract::Dopamine is an important neurotransmitter that plays a key role in a wide range of both locomotive and cognitive functions in humans. Disturbances on the dopaminergic system cause, among others, psychosis, Parkinson's disease and Huntington's disease. Antipsychotics are drugs that interact primarily with the dopamine ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78446-4
更新日期:2020-12-09 00:00:00
abstract::Combined neutron scattering and diffusion nuclear magnetic resonance experiments have been used to reveal significant interregional asymmetries (lateralization) in bovine brain hemispheres in terms of myelin arrangement and water dynamics at micron to atomic scales. Thicker myelin sheaths were found in the left hemisp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-51022-1
更新日期:2019-10-11 00:00:00
abstract::mRNAs lacking 5' untranslated regions (leaderless mRNAs) are molecular relics of an ancient translation initiation pathway. Nevertheless, they still represent a significant portion of transcriptome in some taxons, including a number of eukaryotic species. In bacteria and archaea, the leaderless mRNAs can bind non-diss...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37905
更新日期:2016-11-28 00:00:00
abstract::The ends of eukaryotic chromosomes are capped by telomeres which consist of tandem G-rich DNA repeats stabilized by the shelterin protein complex. Telomeres shorten progressively in most normal cells due to the end replication problem. In more than 85% of cancers however, the telomere length is maintained by telomeras...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06391
更新日期:2014-09-29 00:00:00