Abstract：
:Combined neutron scattering and diffusion nuclear magnetic resonance experiments have been used to reveal significant interregional asymmetries (lateralization) in bovine brain hemispheres in terms of myelin arrangement and water dynamics at micron to atomic scales. Thicker myelin sheaths were found in the left hemisphere using neutron diffraction. 4.7 T dMRI and quasi-elastic neutron experiments highlighted significant differences in the properties of water dynamics in the two hemispheres. The results were interpreted in terms of hemisphere-dependent cellular composition (number of neurons, cell distribution, etc.) as well as specificity of neurological functions (such as preferential networking).
journal_name
Sci Repjournal_title
Scientific reportsauthors
Natali F,Dolce C,Peters J,Stelletta C,Demé B,Ollivier J,Leduc G,Cupane A,Barbier ELdoi
10.1038/s41598-019-51022-1subject
Has Abstractpub_date
2019-10-11 00:00:00pages
14694issue
1issn
2045-2322pii
10.1038/s41598-019-51022-1journal_volume
9pub_type
杂志文章abstract：:INK4 locus at chromosome 9p21 has been reported to be associated with primary open angle glaucoma (POAG) and its subtypes along with the associated optic disc parameters across the populations of European, Japanese and African ancestries. The locus encodes three tumor suppressor genes namely CDKN2A, ARF, CDKN2B and a ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05115
更新日期：2014-05-30 00:00:00
abstract：:In this study, we describe a web-based resource, developed for assisting the scientific community in designing an effective therapeutics against the Ebola virus. Firstly, we predicted and identified experimentally validated epitopes in each of the antigens/proteins of the five known ebolaviruses. Secondly, we generate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24782
更新日期：2016-04-26 00:00:00
abstract：:Turner syndrome (TS) is associated with decreased bone mineral density and increased fracture rate. However, the developmental trajectory of bone density or body composition in patients with TS is still unclear. The present study tested the hypothesis that different karyotypes and/or age contributes to abnormal body c...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/srep38026
更新日期：2016-11-30 00:00:00
abstract：:Raman microspectroscopy provides the means to obtain local orientations on polycrystalline materials at the submicrometer level. The present work demonstrates how orientation-distribution maps composed of Raman intensity distributions can be acquired on large areas of several hundreds of square micrometers. A polycrys...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18410
更新日期：2015-12-17 00:00:00
abstract：:Understanding the complex dynamics of cardio-respiratory coupling sheds light on the underlying mechanisms governing the communication between these two physiological systems. Previous research has predominantly considered the coupling at respiratory rates slower than the heart rate and shown that respiratory oscillat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38058-5
更新日期：2019-02-07 00:00:00
abstract：:The Goos-Hänchen (GH) shifts in the reflected light are investigated both for p and s polarized partial coherent light beams incident on epsilon-near-zero (ENZ) metamaterials. In contrary to the coherent counterparts, the magnitude of GH shift becomes non-zero for p polarized partial coherent light beam; while GH shif...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26504
更新日期：2016-05-23 00:00:00
abstract：:We have studied the transformation of carbides in AISI M42 high-speed steels in the temperature window used for forging. The annealing was found to result in the partial transformation of the large, metastable M2C carbides into small, more stable grains of M6C, with an associated change in the crystal orientation. In ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16202
更新日期：2015-11-05 00:00:00
abstract：:Through combined three-dimensional electromagnetic and particle tracking simulations we demonstrate a THz driven electron streak camera featuring a temporal resolution on the order of a femtosecond. The ultrafast streaking field is generated in a resonant THz sub-wavelength antenna which is illuminated by an intense s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05645
更新日期：2014-07-10 00:00:00
abstract：:Amino acid biosynthesis pathways observed in nature typically require enzymes that are made with the amino acids they produce. For example, Escherichia coli produces cysteine from serine via two enzymes that contain cysteine: serine acetyltransferase (CysE) and O-acetylserine sulfhydrylase (CysK/CysM). To solve this c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-19920-y
更新日期：2018-01-29 00:00:00
abstract：:The crystal structure of the Sb6O13 oxide, exhibiting a defect pyrochlore crystal structure with atomic vacancies, has been studied using a complete set of state-of-the-art techniques. The degree of antimony disproportionation in Sb3+ and Sb5+ valence states has been directly determined around 36% and 64%, respectivel...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73860-0
更新日期：2020-10-12 00:00:00
abstract：:We conducted extensive molecular dynamics simulations to investigate the thermal conductivity of polycrystalline hexagonal boron-nitride (h-BN) films. To this aim, we constructed large atomistic models of polycrystalline h-BN sheets with random and uniform grain configuration. By performing equilibrium molecular dynam...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13228
更新日期：2015-08-19 00:00:00
abstract：:This corrects the article DOI: 10.1038/srep34617. ...
journal_title：Scientific reports
pub_type： 杂志文章,已发布勘误
doi：10.1038/srep42267
更新日期：2017-09-27 00:00:00
abstract：:Increasing grain zinc (Zn) concentration of cereals for minimizing Zn malnutrition in two billion people represents an important global humanitarian challenge. Grain Zn in field-grown wheat at the global scale ranges from 20.4 to 30.5 mg kg-1, showing a solid gap to the biofortification target for human health (40 mg ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07484-2
更新日期：2017-08-01 00:00:00
abstract：:Unlike the constant nature of elastic coefficients of isotropic bulk materials, the Young's (E) and shear (μ) moduli of nano-structured (NS) gyroid metamaterials change with relative density (ρ), but at different rates depending on the cell size of the structure. These elastic behaviors displayed by E and μ cause cros...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10978-8
更新日期：2017-09-05 00:00:00
abstract：:Both plant neighbourhood composition and drought have well-known independent effects on insect herbivore performance, but their interactive effects remain elusive. In this study we performed a laboratory experiment to investigate the independent and combined effects of plant neighbourhood composition and drought on th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24299-x
更新日期：2018-04-12 00:00:00
abstract：:Our data about pathogenesis of hepatic steatosis after liver transplantation is scarce. This study aimed to investigate the association between serum adipokines and insulin resistance with hepatic steatosis in liver transplant recipients. We investigated the association between insulin resistance, serum adiponectin, i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69571-1
更新日期：2020-07-29 00:00:00
abstract：:Stem cell therapy has long been considered a promising mode of treatment for many incurable diseases. Human mesenchymal stem cells (hMSCs) have provided the most promising results to date for regenerative medicine. Nevertheless, due to several obstacles such as difficulty in sourcing and characterizing hMSCs, they rem...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42669-x
更新日期：2019-04-16 00:00:00
abstract：:Understanding cell-bubble interactions is crucial for preventing bubble related pathologies and harnessing their potential therapeutic benefits. Bubbles can occur in the body as a result of therapeutic intravenous administration, surgery, infections or decompression. Subsequent interactions with living cells, may resu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06678-y
更新日期：2017-07-24 00:00:00
abstract：:Amplification and sequencing of 16S amplicons are widely used for profiling the structure of oral microbiota. However, it remains not clear whether and to what degree DNA extraction and targeted 16S rRNA hypervariable regions influence the analysis. Based on a mock community consisting of five oral bacterial species i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34294-x
更新日期：2018-11-05 00:00:00
abstract：:Differential scanning fluorimetry is a popular method to estimate the stability of a protein in distinct buffer conditions by determining its 'melting point'. The method requires a temperature controlled fluorescence spectrometer or a RT-PCR machine. Here, we introduce a low-budget version of a microcontroller based h...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-19702-6
更新日期：2018-01-23 00:00:00
abstract：:The aim of the present study was to evaluate the association between statin use and the risk of age-related macular degeneration (AMD). A systematic search of the PubMed, EMBASE and ISI web of science databases was used to identify eligible published literatures without language restrictions up to April 2015. Summary ...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/srep18280
更新日期：2015-12-14 00:00:00
abstract：:In this work, we report our study of protein expression in rat peri-infarct tissue, 48 h after the induction of permanent focal cerebral ischemia. Two proteomic approaches, gel electrophoresis with mass spectrometry and combined fractional diagonal chromatography (COFRADIC), were performed using tissue samples from th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12030
更新日期：2015-07-08 00:00:00
abstract：:Why humans cooperate in large groups and with non-kin remains a puzzle for researchers across the natural and social sciences. Investigating whether cooperation is sexually selected could contribute to an understanding of the evolution of human cooperation. Competition for access to mates could indeed select for coope...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29819
更新日期：2016-07-14 00:00:00
abstract：:The chemokine CCL3 is frequently overexpressed in malignancies and overexpression leads to microenvironmental dysfunction. In murine models of chronic myelogenous leukemia (CML), CCL3 is critical for the maintenance of a leukemia stem cell population, and leukemia progression. With CCL3 implicated as a potentially via...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32978-y
更新日期：2018-10-02 00:00:00
abstract：:Cas13 endonuclease activity depends on the RNA local secondary structure with strong preference for single-stranded (SS) regions. Hence, it becomes indispensable to identify the SS regions for effective Cas13 mediated RNA knockdown. We herein present rational gRNA design by integrating experimental structure-seq data ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68459-4
更新日期：2020-07-14 00:00:00
abstract：:Intracerebroventricular (ICV) administration of ouabain, an inhibitor of the Na, K-ATPase, is an approach used to study the physiological functions of the Na, K-ATPase and cardiotonic steroids in the central nervous system, known to cause mania-like hyperactivity in rats. We describe a mouse model of ouabain-induced m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52058-z
更新日期：2019-10-30 00:00:00
abstract：:We have developed a framework to convert an arbitrary integer factorization problem to an executable Ising model by first writing it as an optimization function then transforming the k-bit coupling (k ≥ 3) terms to quadratic terms using ancillary variables. Our resource-efficient method uses [Formula: see text] binary...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36058-z
更新日期：2018-12-05 00:00:00
abstract：:The vertical migration of zooplankton and micronekton (hereafter 'zooplankton') has ramifications throughout the food web. Here, we present the first evidence that climate fluctuations affect the vertical migration of zooplankton in the Southern Ocean, based on multi-year acoustic backscatter data from one of the deep...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46423-1
更新日期：2019-07-12 00:00:00
abstract：:Sixty-six million years ago, an asteroid approximately 9 km in diameter hit the hydrocarbon- and sulfur-rich sedimentary rocks in what is now Mexico. Recent studies have shown that this impact at the Yucatan Peninsula heated the hydrocarbon and sulfur in these rocks, forming stratospheric soot and sulfate aerosols and...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14199-x
更新日期：2017-11-09 00:00:00
abstract：:X-ray phase-contrast imaging (XPCI) can dramatically improve soft tissue contrast in X-ray medical imaging. Despite worldwide efforts to develop novel XPCI systems, a numerical framework to rigorously predict the performance of a clinical XPCI system at a human scale is not yet available. We have developed such a tool...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12011
更新日期：2015-07-14 00:00:00
