Drought and plant neighbourhood interactively determine herbivore consumption and performance.

abstract：:The mechanisms by which the airborne pathogen Mycobacterium tuberculosis spreads within the lung and leaves its primary niche to colonize other organs, thus inducing extrapulmonary forms of tuberculosis (TB) in humans, remains poorly understood. Herein, we used a transcriptomic approach to investigate the host cell ge...

journal_title：Scientific reports

authors： Polena H,Boudou F,Tilleul S,Dubois-Colas N,Lecointe C,Rakotosamimanana N,Pelizzola M,Andriamandimby SF,Raharimanga V,Charles P,Herrmann JL,Ricciardi-Castagnoli P,Rasolofo V,Gicquel B,Tailleux L

更新日期：2016-09-12 00:00:00

abstract：:The use of nanocarriers composed of polyethylene glycol- and polyvinyl alcohol-coated vesicles encapsulating active molecules in place of conventional chemotherapy drugs can reduce many of the chemotherapy-associated challenges because of the increased drug concentration at the diseased area in the body. The present s...

journal_title：Scientific reports

authors： Ebadi M,Bullo S,Buskara K,Hussein MZ,Fakurazi S,Pastorin G

更新日期：2020-12-09 00:00:00

abstract：:cAMP is one of the most important second messengers in biological processes. Cellular dynamics of cAMP have been investigated using a series of fluorescent indicators; however, their sensitivity was sub-optimal for detecting cAMP dynamics at a low concentration range, due to a low ligand affinity and/or poor dynamic r...

journal_title：Scientific reports

authors： Ohta Y,Furuta T,Nagai T,Horikawa K

更新日期：2018-01-30 00:00:00

abstract：:Spliced leader dependent trans-splicing (SLTS) has been described as an important RNA regulatory process that occurs in different organisms, including the trematode Schistosoma mansoni. We identified more than seven thousand putative SLTS sites in the parasite, comprising genes with a wide spectrum of functional class...

journal_title：Scientific reports

authors： Boroni M,Sammeth M,Gava SG,Jorge NAN,Macedo AM,Machado CR,Mourão MM,Franco GR

更新日期：2018-03-01 00:00:00

abstract：:The lack of a precisely-dated, unequivocal climate proxy from northern China, where precipitation variability is traditionally considered as an East Asian summer monsoon (EASM) indicator, impedes our understanding of the behaviour and dynamics of the EASM. Here we present a well-dated, pollen-based, ~20-yr-resolution ...

journal_title：Scientific reports

authors： Chen F,Xu Q,Chen J,Birks HJ,Liu J,Zhang S,Jin L,An C,Telford RJ,Cao X,Wang Z,Zhang X,Selvaraj K,Lu H,Li Y,Zheng Z,Wang H,Zhou A,Dong G,Zhang J,Huang X,Bloemendal J,Rao Z

更新日期：2015-06-18 00:00:00

abstract：:Elastography plays a key role in characterizing soft media such as biological tissue. Although this technology has found widespread use in both clinical diagnostics and basic science research, nearly all methods require direct physical contact with the object of interest and can even be invasive. For a number of appli...

journal_title：Scientific reports

authors： Ambroziński Ł,Song S,Yoon SJ,Pelivanov I,Li D,Gao L,Shen TT,Wang RK,O'Donnell M

更新日期：2016-12-23 00:00:00

abstract：:Type 2 diabetes (T2D) is emerging as one of the serious public health issues in both developed and developing counties. Here, we surveyed the worldwide population differentiation in T2D-associated variants and assessed the genetic burden of the disease in an ongoing Tehran Cardio-Metabolic Genetic Study (TCGS) cohort ...

journal_title：Scientific reports

authors： Moazzam-Jazi M,Najd Hassan Bonab L,Zahedi AS,Daneshpour MS

更新日期：2020-08-19 00:00:00

abstract：:The accurate calculation of decimal fractions is still a challenge for the binary-coded computations that rely on von Neumann paradigm. Here, we report a kind of memristive abacus based on synaptic Ag-Ge-Se device, in which the memristive long-term potentiation and depression are caused by a chemically driven phase tr...

journal_title：Scientific reports

authors： Xu H,Xia Y,Yin K,Lu J,Yin Q,Yin J,Sun L,Liu Z

更新日期：2013-01-01 00:00:00

abstract：:Microalgal harvesting and dewatering are the main bottlenecks that need to be overcome to tap the potential of microalgae for production of valuable compounds. Water surface-floating microalgae form robust biofilms, float on the water surface along with gas bubbles entrapped under the biofilms, and have great potentia...

journal_title：Scientific reports

authors： Maeda Y,Nojima D,Sakurai M,Nomaguchi T,Ichikawa M,Ishizuka Y,Tanaka T

更新日期：2019-08-01 00:00:00

abstract：:Oxaliplatin is a key chemotherapy drug in patients with colorectal cancer. Administration of oxaliplatin via a peripheral vein often causes vascular pain. However, no studies have evaluated vascular pain in patients with colorectal cancer in relation to peripheral venous administration of chemotherapy with or without ...

journal_title：Scientific reports

authors： Matsuoka T,Yoshida Y,Aisu N,Yamada T,Mogi A,Komono A,Sakamoto R,Kojima D,Yoshimatsu G,Kiyomi F,Kodama S,Hasegawa S

更新日期：2019-02-12 00:00:00

abstract：:Ubiquinol-cytochrome c reductase hinge protein (UQCRH) is the hinge protein for the multi-subunit complex III of the mitochondrial electron transport chain and is involved in the electron transfer reaction between cytochrome c1 and c. Recent genome-wide transcriptomic and epigenomic profiling of clear cell renal cell ...

journal_title：Scientific reports

authors： Luo Y,Medina Bengtsson L,Wang X,Huang T,Liu G,Murphy S,Wang C,Koren J 3rd,Schafer Z,Lu X

更新日期：2020-09-14 00:00:00

abstract：:Treponema pallidum subsp. pallidum, the causative agent of syphilis, is a highly invasive spirochete pathogen that uses the vasculature to disseminate throughout the body. Identification of bacterial factors promoting dissemination is crucial for syphilis vaccine development. An important step in dissemination is bact...

journal_title：Scientific reports

authors： Kao WA,Pětrošová H,Ebady R,Lithgow KV,Rojas P,Zhang Y,Kim YE,Kim YR,Odisho T,Gupta N,Moter A,Cameron CE,Moriarty TJ

更新日期：2017-05-08 00:00:00

abstract：:COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. We investigated celecoxib (a COX-2 inhibitor) alone and with standard anti-tuberc...

journal_title：Scientific reports

authors： Naftalin CM,Verma R,Gurumurthy M,Hee KH,Lu Q,Yeo BCM,Tan KH,Lin W,Yu B,Seng KY,Lee LS,Paton NI

更新日期：2018-09-10 00:00:00

abstract：:Three-dimensional (3D) bioprinting is driving major innovations in the area of cartilage tissue engineering. Extrusion-based 3D bioprinting necessitates a phase change from a liquid bioink to a semi-solid crosslinked network achieved by a photo-initiated free radical polymerization reaction that is known to be cytotox...

journal_title：Scientific reports

authors： Duchi S,Onofrillo C,O'Connell CD,Blanchard R,Augustine C,Quigley AF,Kapsa RMI,Pivonka P,Wallace G,Di Bella C,Choong PFM

更新日期：2017-07-19 00:00:00

abstract：:Lower respiratory infections, such as community-acquired pneumonia (CAP), and chronic obstructive pulmonary disease (COPD) rank among the most frequent causes of death worldwide. Improved diagnostics and profound pathophysiological insights are urgent clinical needs. In our cohort, we analysed transcriptional networks...

journal_title：Scientific reports

authors： Bertrams W,Griss K,Han M,Seidel K,Klemmer A,Sittka-Stark A,Hippenstiel S,Suttorp N,Finkernagel F,Wilhelm J,Greulich T,Vogelmeier CF,Vera J,Schmeck B

更新日期：2020-01-14 00:00:00

abstract：:Intracontinental biotic divisions across the vast Palaearctic region are not well-characterized. Past research has revealed patterns ranging from a lack of population structure to deep divergences along varied lines of separation. Here we compared biogeographic patterns of two Palaearctic shorebirds with different hab...

journal_title：Scientific reports

authors： Tan HZ,Ng EYX,Tang Q,Allport GA,Jansen JJFJ,Tomkovich PS,Rheindt FE

更新日期：2019-12-03 00:00:00

abstract：:We sequenced coding regions of the cluster of differentiation 36 (CD36) gene in 184 French individuals of European ancestry presenting simultaneously with type 2 diabetes (T2D), arterial hypertension, dyslipidemia, and coronary heart disease. We identified rare missense mutations (p.Pro191Leu/rs143150225 and p.Ala252V...

journal_title：Scientific reports

authors： Meyre D,Andress EJ,Sharma T,Snippe M,Asif H,Maharaj A,Vatin V,Gaget S,Besnard P,Choquet H,Froguel P,Linton KJ

更新日期：2019-11-20 00:00:00

abstract：:Mid-infrared spectroscopy is of great importance in many areas and its integration with thin-film technology can economically enrich the functionalities of many existing devices. In this paper we propose a graphene-based ultra-compact spectrometer (several micrometers in size) that is compatible with complementary met...

journal_title：Scientific reports

authors： Wang X,Chen C,Pan L,Wang J

更新日期：2016-08-30 00:00:00

abstract：:A new miniplate applied differently from conventional application method for bone fixation has been developed. The novel approach is the insertion of the screw into the bone before miniplate installation. This study aimed to assess the stress distribution of a newly designed Yang's Keyhole (YK)- plate for segmental-bo...

journal_title：Scientific reports

authors： Kim JW,Park KN,Lee CH,Kim YS,Kim YH,Yang BE

更新日期：2018-06-12 00:00:00

abstract：:Membrane fouling remains an obstacle to wide-spread applications of membrane bioreactors (MBRs) for wastewater treatment and reclamation. Herein, we report a simple method to prepare a composite conductive microfiltration (MF) membrane by introducing a stainless steel mesh into a polymeric MF membrane and to effective...

journal_title：Scientific reports

authors： Huang J,Wang Z,Zhang J,Zhang X,Ma J,Wu Z

更新日期：2015-03-18 00:00:00

abstract：:Knee osteoarthritis (OA) is the most common musculoskeletal disorder. OA diagnosis is currently conducted by assessing symptoms and evaluating plain radiographs, but this process suffers from subjectivity. In this study, we present a new transparent computer-aided diagnosis method based on the Deep Siamese Convolution...

journal_title：Scientific reports

authors： Tiulpin A,Thevenot J,Rahtu E,Lehenkari P,Saarakkala S

更新日期：2018-01-29 00:00:00

abstract：:Seed size/weight is a major agronomic trait which determine crop productivity in legumes. To understand the genetic basis of seed size determination, we sought to identify DNA polymorphisms between two small (Himchana 1 and Pusa 362) and two large-seeded (JGK 3 and PG 0515) chickpea cultivars via whole genome resequen...

journal_title：Scientific reports

authors： Rajkumar MS,Garg R,Jain M

更新日期：2018-11-14 00:00:00

abstract：:Tissue fibrosis underlies the majority of human mortality to date with close to half of all reported deaths having a fibrotic etiology. The progression of fibrosis is very complex and reputed irreversible once established. Although some preventive options are being reported, therapeutic options are still scarce and in...

journal_title：Scientific reports

authors： Nono JK,Fu K,Mpotje T,Varrone G,Aziz NA,Mosala P,Hlaka L,Kamdem SD,Xu D,Spangenberg T,Brombacher F

更新日期：2020-06-30 00:00:00

abstract：:CD147/EMMPRIN (extracellular matrix metalloproteinase inducer) plays an important role in tumor progression and a number of studies have suggested that it is an indicator of tumor prognosis. This current meta-analysis systematically reevaluated the predictive potential of CD147/EMMPRIN in various cancers. We searched ...

journal_title：Scientific reports

authors： Xin X,Zeng X,Gu H,Li M,Tan H,Jin Z,Hua T,Shi R,Wang H

更新日期：2016-09-09 00:00:00

abstract：:Epoxyeicosatrienoic acids (EETs) are produced by cytochrome P450 epoxygenases from arachidonic acid, and their rapid metabolism is mainly through soluble epoxide hydrolase (sEH). EETs exert vasodilatory, anti-inflammatory, anti-apoptotic, and pro-angiogenic effects. Administration of sEH inhibitors before or at the on...

journal_title：Scientific reports

authors： Tu R,Armstrong J,Lee KSS,Hammock BD,Sapirstein A,Koehler RC

更新日期：2018-03-27 00:00:00

abstract：:Plasma free amino acid (PFAA) profile is highlighted in its association with visceral obesity and hyperinsulinemia, and future diabetes. Indeed PFAA profiling potentially can evaluate individuals' future risks of developing lifestyle-related diseases, in addition to diabetes. However, few studies have been performed e...

journal_title：Scientific reports

authors： Yamakado M,Nagao K,Imaizumi A,Tani M,Toda A,Tanaka T,Jinzu H,Miyano H,Yamamoto H,Daimon T,Horimoto K,Ishizaka Y

更新日期：2015-07-09 00:00:00

abstract：:Ceramide is one of the most important intercellular components responsible for the barrier and moisture retention functions of the skin. Because of the risks involved with using products of animal origin and the low productivity of plants, the availability of ceramides is currently limited. In this study, we successfu...

journal_title：Scientific reports

authors： Murakami S,Shimamoto T,Nagano H,Tsuruno M,Okuhara H,Hatanaka H,Tojo H,Kodama Y,Funato K

更新日期：2015-11-17 00:00:00

abstract：:Angiogenesis is one of the hallmarks of cancer and, as such, one of the alternative general targets for anticancer therapy. Since angiogenesis is a complex process involving a high number of interconnected components, a network approach would be a convenient systemic way to analyse responses to directed drug attacks. ...

journal_title：Scientific reports

authors： Montañez R,Sánchez-Jiménez F,Quesada AR,Medina MÁ

更新日期：2011-01-01 00:00:00

abstract：:Laser-driven ultrafast electron emission offers the possibility of manipulation and control of coherent electron motion in ultrashort spatiotemporal scales. Here, an analytical solution is constructed for the highly nonlinear electron emission from a dc biased metal surface illuminated by a single frequency laser, by ...

journal_title：Scientific reports

authors： Zhang P,Lau YY

更新日期：2016-01-28 00:00:00

abstract：:We investigate the growth of Cu films on two different Cu seed layers: one with regular <111>-oriented grains and the other with very strong <111>-preferred orientation. It is found that densely-packed nanotwinned Cu (nt-Cu) can be grown by pulsed electroplating on the strong <111>-oriented Cu seed layer without a ran...

journal_title：Scientific reports

authors： Liu CM,Lin HW,Lu CL,Chen C

更新日期：2014-08-19 00:00:00